Project name: 4g6j:L
Status: done
submitted: 2019-03-20 20:16:34, status changed: 2019-03-20 20:28:44
Settings
|
Chain sequence(s)
|
L: EIVLTQSPDFQSVTPKEKVTITCRASQSIGSSLHWYQQKPDQSPKLLIKYASQSFSGVPSRFSGSGSGTDFTLTINSLEAEDAAAYYCHQSSSLPFTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6185
-
Maximal score value
-
2.6204
-
Average score
-
-0.7709
-
Total score value
-
-163.4291
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
L |
-0.8970 |
|
| 2 |
I |
L |
0.2893 |
|
| 3 |
V |
L |
1.2988 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.4684 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-1.0262 |
|
| 8 |
P |
L |
-0.9412 |
|
| 9 |
D |
L |
-1.6565 |
|
| 10 |
F |
L |
-0.3376 |
|
| 11 |
Q |
L |
-0.6565 |
|
| 12 |
S |
L |
-0.4714 |
|
| 13 |
V |
L |
-1.3340 |
|
| 14 |
T |
L |
-1.9438 |
|
| 15 |
P |
L |
-2.6690 |
|
| 16 |
K |
L |
-3.4871 |
|
| 17 |
E |
L |
-3.6185 |
|
| 18 |
K |
L |
-3.1880 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6910 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.7997 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.1966 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-0.9323 |
|
| 27 |
Q |
L |
-1.5624 |
|
| 28 |
S |
L |
-1.3788 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
G |
L |
-0.7513 |
|
| 31 |
S |
L |
-0.2321 |
|
| 32 |
S |
L |
-0.0360 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
H |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.3316 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.3924 |
|
| 39 |
K |
L |
-1.9778 |
|
| 40 |
P |
L |
-2.0802 |
|
| 41 |
D |
L |
-2.7038 |
|
| 42 |
Q |
L |
-2.4413 |
|
| 43 |
S |
L |
-1.6780 |
|
| 44 |
P |
L |
-1.5058 |
|
| 45 |
K |
L |
-1.5106 |
|
| 46 |
L |
L |
-0.3240 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
K |
L |
-0.2039 |
|
| 50 |
Y |
L |
0.4946 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.7010 |
|
| 53 |
Q |
L |
-1.0478 |
|
| 54 |
S |
L |
-0.4446 |
|
| 55 |
F |
L |
0.4344 |
|
| 56 |
S |
L |
-0.0510 |
|
| 57 |
G |
L |
-0.2276 |
|
| 58 |
V |
L |
-0.0881 |
|
| 59 |
P |
L |
-0.3173 |
|
| 60 |
S |
L |
-0.6682 |
|
| 61 |
R |
L |
-1.3133 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.8209 |
|
| 64 |
G |
L |
-0.5785 |
|
| 65 |
S |
L |
-0.6394 |
|
| 66 |
G |
L |
-0.8995 |
|
| 67 |
S |
L |
-0.7559 |
|
| 68 |
G |
L |
-1.2690 |
|
| 69 |
T |
L |
-1.7468 |
|
| 70 |
D |
L |
-2.0109 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7440 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.8170 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
N |
L |
-2.6955 |
|
| 77 |
S |
L |
-2.9016 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
E |
L |
-3.4560 |
|
| 80 |
A |
L |
-2.9820 |
|
| 81 |
E |
L |
-3.0894 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
A |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
A |
L |
-0.2965 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.4071 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
H |
L |
1.1987 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
S |
L |
1.0420 |
|
| 92 |
S |
L |
0.3046 |
|
| 93 |
S |
L |
0.7299 |
|
| 94 |
L |
L |
1.6924 |
|
| 95 |
P |
L |
1.1290 |
|
| 96 |
F |
L |
2.6204 |
|
| 97 |
T |
L |
2.0610 |
|
| 98 |
F |
L |
2.5733 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
P |
L |
0.0410 |
|
| 101 |
G |
L |
-0.2167 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-0.6901 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
D |
L |
0.0000 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.3465 |
|
| 108 |
R |
L |
-1.1162 |
|
| 109 |
T |
L |
-0.1477 |
|
| 110 |
V |
L |
0.4863 |
|
| 111 |
A |
L |
-0.0080 |
|
| 112 |
A |
L |
-0.2690 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1309 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.1885 |
|
| 117 |
I |
L |
1.1853 |
|
| 118 |
F |
L |
1.4381 |
|
| 119 |
P |
L |
0.0064 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.7504 |
|
| 122 |
D |
L |
-3.2224 |
|
| 123 |
E |
L |
-3.4492 |
|
| 124 |
Q |
L |
-2.4092 |
|
| 125 |
L |
L |
-2.3904 |
|
| 126 |
K |
L |
-3.0649 |
|
| 127 |
S |
L |
-1.9398 |
|
| 128 |
G |
L |
-1.3496 |
|
| 129 |
T |
L |
-1.1450 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0613 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7359 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.4528 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6533 |
|
| 138 |
N |
L |
-1.3226 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.6527 |
|
| 142 |
R |
L |
-2.8317 |
|
| 143 |
E |
L |
-3.0693 |
|
| 144 |
A |
L |
-2.2584 |
|
| 145 |
K |
L |
-2.3077 |
|
| 146 |
V |
L |
-1.1673 |
|
| 147 |
Q |
L |
-0.6685 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.5617 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.6744 |
|
| 152 |
N |
L |
-1.2278 |
|
| 153 |
A |
L |
-0.1793 |
|
| 154 |
L |
L |
0.7430 |
|
| 155 |
Q |
L |
-0.1090 |
|
| 156 |
S |
L |
-0.5342 |
|
| 157 |
G |
L |
-0.9639 |
|
| 158 |
N |
L |
-0.8855 |
|
| 159 |
S |
L |
-1.4127 |
|
| 160 |
Q |
L |
-2.3010 |
|
| 161 |
E |
L |
-2.2956 |
|
| 162 |
S |
L |
-1.2420 |
|
| 163 |
V |
L |
-0.5291 |
|
| 164 |
T |
L |
-1.1020 |
|
| 165 |
E |
L |
-2.4221 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.5876 |
|
| 168 |
S |
L |
-2.8272 |
|
| 169 |
K |
L |
-3.0028 |
|
| 170 |
D |
L |
-2.1517 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9421 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4329 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5995 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.4530 |
|
| 181 |
L |
L |
-0.6347 |
|
| 182 |
S |
L |
-0.9862 |
|
| 183 |
K |
L |
-1.8812 |
|
| 184 |
A |
L |
-1.7553 |
|
| 185 |
D |
L |
-2.5005 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.3154 |
|
| 188 |
K |
L |
-3.5329 |
|
| 189 |
H |
L |
-3.0928 |
|
| 190 |
K |
L |
-3.1466 |
|
| 191 |
V |
L |
-1.5945 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.8693 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.1832 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.5417 |
|
| 200 |
G |
L |
-0.4237 |
|
| 201 |
L |
L |
-0.2411 |
|
| 202 |
S |
L |
-0.4400 |
|
| 203 |
S |
L |
-0.4035 |
|
| 204 |
P |
L |
-0.5399 |
|
| 205 |
V |
L |
-0.0318 |
|
| 206 |
T |
L |
-0.5227 |
|
| 207 |
K |
L |
-0.6457 |
|
| 208 |
S |
L |
-0.5717 |
|
| 209 |
F |
L |
-0.8602 |
|
| 210 |
N |
L |
-2.1780 |
|
| 211 |
R |
L |
-2.5025 |
|
| 212 |
G |
L |
-1.6469 |
|