| Chain sequence(s) |
H: QVQLQESGPGLVKPSQTLSLTCTVSGGSISSFNYYWSWIRHHPGKGLEWIGYIYYSGSTYSNPSLKSRVTISVDTSKNQFSLTLSSVTAADTAVYYCARGYNWNYFDYWGQGTLVTVS L: EIVMTQSPATLSVSPGERATLSCRASQSVDNNLVWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWPPWTFGQGTKVEIK |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | E | L | -1.3795 | |
| 2 | I | L | -0.0634 | |
| 3 | V | L | 0.9308 | |
| 4 | M | L | 0.0000 | |
| 5 | T | L | -0.4654 | |
| 6 | Q | L | 0.0000 | |
| 7 | S | L | -0.6489 | |
| 8 | P | L | -0.4653 | |
| 9 | A | L | -0.4848 | |
| 10 | T | L | -0.6422 | |
| 11 | L | L | -0.4126 | |
| 12 | S | L | -0.8675 | |
| 13 | V | L | 0.0000 | |
| 14 | S | L | -1.6628 | |
| 15 | P | L | -1.9771 | |
| 16 | G | L | -2.3088 | |
| 17 | E | L | -3.5143 | |
| 18 | R | L | -3.1788 | |
| 19 | A | L | 0.0000 | |
| 20 | T | L | -0.7354 | |
| 21 | L | L | 0.0000 | |
| 22 | S | L | -0.7719 | |
| 23 | C | L | 0.0000 | |
| 24 | R | L | -1.7225 | |
| 25 | A | L | -0.8905 | |
| 26 | S | L | -0.7774 | |
| 27 | Q | L | -1.5477 | |
| 28 | S | L | -1.8932 | |
| 29 | V | L | 0.0000 | |
| 30 | D | L | -3.0794 | |
| 31 | N | L | -2.5500 | |
| 32 | N | L | -2.0134 | |
| 33 | L | L | 0.0000 | |
| 34 | V | L | 0.0000 | |
| 35 | W | L | 0.0000 | |
| 36 | Y | L | 0.0000 | |
| 37 | Q | L | -1.0255 | |
| 38 | Q | L | 0.0000 | |
| 39 | K | L | -1.6697 | |
| 40 | P | L | -1.0636 | |
| 41 | G | L | -1.4872 | |
| 42 | Q | L | -2.2692 | |
| 43 | A | L | -1.6198 | |
| 44 | P | L | 0.0000 | |
| 45 | R | L | -2.2155 | |
| 46 | L | L | 0.0000 | |
| 47 | L | L | 0.0000 | |
| 48 | I | L | 0.0000 | |
| 49 | Y | L | -0.4931 | |
| 50 | G | L | -0.9752 | |
| 51 | A | L | 0.0000 | |
| 52 | S | L | -0.9746 | |
| 53 | T | L | -0.9122 | |
| 54 | R | L | -1.5573 | |
| 55 | A | L | -1.0886 | |
| 56 | T | L | -0.6409 | |
| 57 | G | L | -0.6226 | |
| 58 | I | L | -0.6708 | |
| 59 | P | L | -0.4399 | |
| 60 | A | L | -0.4823 | |
| 61 | R | L | -0.9606 | |
| 62 | F | L | 0.0000 | |
| 63 | S | L | -0.6210 | |
| 64 | G | L | -0.6129 | |
| 65 | S | L | -0.8906 | |
| 66 | G | L | -1.5730 | |
| 67 | S | L | -2.0924 | |
| 68 | G | L | -2.2135 | |
| 69 | T | L | -2.1984 | |
| 70 | E | L | -2.7262 | |
| 71 | F | L | 0.0000 | |
| 72 | T | L | -0.8163 | |
| 73 | L | L | 0.0000 | |
| 74 | T | L | -0.6212 | |
| 75 | I | L | 0.0000 | |
| 76 | S | L | -1.6416 | |
| 77 | S | L | -2.1630 | |
| 78 | L | L | 0.0000 | |
| 79 | Q | L | -2.3375 | |
| 80 | S | L | -1.4672 | |
| 81 | E | L | -2.0541 | |
| 82 | D | L | 0.0000 | |
| 83 | F | L | -0.7893 | |
| 84 | A | L | 0.0000 | |
| 85 | V | L | -0.6558 | |
| 86 | Y | L | 0.0000 | |
| 87 | Y | L | 0.0000 | |
| 88 | C | L | 0.0000 | |
| 89 | Q | L | 0.0000 | |
| 90 | Q | L | 0.0000 | |
| 91 | Y | L | -0.9544 | |
| 92 | N | L | -2.0343 | |
| 93 | N | L | -1.4298 | |
| 94 | W | L | -0.2192 | |
| 95 | P | L | -0.1482 | |
| 95A | P | L | -0.5036 | |
| 96 | W | L | 0.0000 | |
| 97 | T | L | -0.1275 | |
| 98 | F | L | 0.1111 | |
| 99 | G | L | 0.0000 | |
| 100 | Q | L | -1.3830 | |
| 101 | G | L | 0.0000 | |
| 102 | T | L | 0.0000 | |
| 103 | K | L | -1.3751 | |
| 104 | V | L | 0.0000 | |
| 105 | E | L | -0.8473 | |
| 106 | I | L | 0.2046 | |
| 107 | K | L | -1.3148 | |
| 1 | Q | H | -1.5155 | |
| 2 | V | H | -1.2402 | |
| 3 | Q | H | -1.8704 | |
| 4 | L | H | 0.0000 | |
| 5 | Q | H | -1.9417 | |
| 6 | E | H | -1.4616 | |
| 7 | S | H | -0.8274 | |
| 8 | G | H | -0.2379 | |
| 9 | P | H | 0.1281 | |
| 10 | G | H | 0.7706 | |
| 11 | L | H | 1.1706 | |
| 12 | V | H | 0.0000 | |
| 13 | K | H | -1.8310 | |
| 14 | P | H | -1.4453 | |
| 15 | S | H | -1.1920 | |
| 16 | Q | H | -1.4662 | |
| 17 | T | H | -0.8937 | |
| 18 | L | H | 0.0000 | |
| 19 | S | H | -0.4250 | |
| 20 | L | H | 0.0000 | |
| 21 | T | H | -0.5490 | |
| 22 | C | H | 0.0000 | |
| 23 | T | H | -1.4199 | |
| 24 | V | H | 0.0000 | |
| 25 | S | H | -1.4486 | |
| 26 | G | H | -1.2313 | |
| 27 | G | H | -1.1164 | |
| 28 | S | H | -0.8980 | |
| 29 | I | H | 0.0000 | |
| 30 | S | H | -0.2397 | |
| 31 | S | H | 0.4297 | |
| 31A | F | H | 1.3654 | |
| 31B | N | H | -0.2797 | |
| 32 | Y | H | 0.1323 | |
| 33 | Y | H | 0.0000 | |
| 34 | W | H | 0.0000 | |
| 35 | S | H | 0.0000 | |
| 36 | W | H | 0.0000 | |
| 37 | I | H | 0.0000 | |
| 38 | R | H | 0.0000 | |
| 39 | H | H | -0.8147 | |
| 40 | H | H | -0.9909 | |
| 41 | P | H | -0.9084 | |
| 42 | G | H | -1.5230 | |
| 43 | K | H | -2.4645 | |
| 44 | G | H | -1.6589 | |
| 45 | L | H | 0.0000 | |
| 46 | E | H | -0.8310 | |
| 47 | W | H | 0.0000 | |
| 48 | I | H | 0.0000 | |
| 49 | G | H | 0.0000 | |
| 50 | Y | H | 0.0000 | |
| 51 | I | H | 0.0000 | |
| 52 | Y | H | 0.3187 | |
| 53 | Y | H | 0.2575 | |
| 54 | S | H | -0.0878 | |
| 55 | G | H | -0.2171 | |
| 56 | S | H | -0.1071 | |
| 57 | T | H | -0.0109 | |
| 58 | Y | H | 0.1625 | |
| 59 | S | H | -0.5363 | |
| 60 | N | H | -0.7999 | |
| 61 | P | H | -1.0560 | |
| 62 | S | H | -0.8157 | |
| 63 | L | H | -1.0457 | |
| 64 | K | H | -1.8889 | |
| 65 | S | H | -1.2665 | |
| 66 | R | H | -1.1201 | |
| 67 | V | H | -0.7615 | |
| 68 | T | H | -0.4180 | |
| 69 | I | H | 0.0000 | |
| 70 | S | H | -0.2277 | |
| 71 | V | H | -0.4958 | |
| 72 | D | H | -1.3930 | |
| 73 | T | H | -1.2468 | |
| 74 | S | H | -1.4203 | |
| 75 | K | H | -2.2726 | |
| 76 | N | H | -1.6495 | |
| 77 | Q | H | -1.3979 | |
| 78 | F | H | 0.0000 | |
| 79 | S | H | -0.3085 | |
| 80 | L | H | 0.0000 | |
| 81 | T | H | -0.1896 | |
| 82 | L | H | 0.0000 | |
| 82A | S | H | -0.6041 | |
| 82B | S | H | -0.9058 | |
| 82C | V | H | 0.0000 | |
| 83 | T | H | -0.6365 | |
| 84 | A | H | -0.3038 | |
| 85 | A | H | -0.0203 | |
| 86 | D | H | 0.0000 | |
| 87 | T | H | 0.3372 | |
| 88 | A | H | 0.0000 | |
| 89 | V | H | 0.5205 | |
| 90 | Y | H | 0.0000 | |
| 91 | Y | H | 0.0000 | |
| 92 | C | H | 0.0000 | |
| 93 | A | H | 0.0000 | |
| 94 | R | H | -0.1552 | |
| 95 | G | H | 0.0000 | |
| 96 | Y | H | 0.1171 | |
| 97 | N | H | -0.2342 | |
| 98 | W | H | 0.5518 | |
| 99 | N | H | 0.0757 | |
| 100 | Y | H | -0.0156 | |
| 100A | F | H | 0.0000 | |
| 101 | D | H | -1.0277 | |
| 102 | Y | H | -0.8599 | |
| 103 | W | H | -1.1202 | |
| 104 | G | H | 0.0000 | |
| 105 | Q | H | -1.8453 | |
| 106 | G | H | -0.8165 | |
| 107 | T | H | 0.1394 | |
| 108 | L | H | 1.4712 | |
| 109 | V | H | 0.0000 | |
| 110 | T | H | 0.4923 | |
| 111 | V | H | 0.0000 | |
| 112 | S | H | -0.5649 |