Project name: 3vfg:H

Chain sequence(s)	H: QVQLKESGPGLVAPSQSLSITCTVSGFSVTNYGVHWVRQPPGKGLEWLGVIWAGGITNYNSAFMSRLSISKDNSKSQVFLKMNSLQIDDTAMYYCASRGGHYGYALDYWGQGTSVTVSSASTKGPSVYPLVPGCTSGSSVTLGCLVKGYFPEPVTVKWNYGALSSGVRTVSSVLQSGFYSLSSLVTVPSSTWPSQTVICNVAHPASKTELIKRIEPR
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9082
• Maximal score value: 2.2727
• Average score: -0.4141
• Total score value: -89.8506

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.2504
2	V	H	-0.6477
3	Q	H	-1.2234
4	L	H	0.0000
5	K	H	-1.8034
6	E	H	0.0000
7	S	H	-0.7979
8	G	H	-0.5382
9	P	H	-0.3930
10	G	H	-0.2933
11	L	H	-0.0619
12	V	H	0.0000
13	A	H	-0.4720
14	P	H	-0.7041
15	S	H	-1.1984
16	Q	H	-1.8178
17	S	H	-1.5290
18	L	H	0.0000
19	S	H	-0.7120
20	I	H	0.0000
21	T	H	-0.3969
22	C	H	0.0000
23	T	H	-1.0508
24	V	H	0.0000
25	S	H	-0.8916
26	G	H	-0.8163
27	F	H	-0.4067
28	S	H	-0.6919
29	V	H	0.0000
30	T	H	-1.1236
31	N	H	-1.1802
32	Y	H	-0.2309
33	G	H	0.0940
34	V	H	0.0000
35	H	H	0.0919
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.5277
40	P	H	-1.1852
41	P	H	-1.3582
42	G	H	-1.4443
43	K	H	-2.0887
44	G	H	-0.9760
45	L	H	0.5445
46	E	H	-0.0216
47	W	H	0.5294
48	L	H	0.0000
49	G	H	0.0000
50	V	H	0.0000
51	I	H	0.0000
52	W	H	0.5472
53	A	H	-0.2274
54	G	H	-0.0576
55	G	H	0.3608
56	I	H	1.6594
57	T	H	0.5864
58	N	H	-0.2067
59	Y	H	0.1507
60	N	H	0.0273
61	S	H	0.0969
62	A	H	0.2521
63	F	H	0.0000
64	M	H	0.8424
65	S	H	0.0460
66	R	H	-0.5661
67	L	H	-0.3907
68	S	H	-0.5898
69	I	H	0.0000
70	S	H	-0.3800
71	K	H	-1.3013
72	D	H	-2.1937
73	N	H	-2.6845
74	S	H	-2.0326
75	K	H	-2.6153
76	S	H	-1.8833
77	Q	H	-1.6443
78	V	H	0.0000
79	F	H	-0.0414
80	L	H	0.0000
81	K	H	-1.1072
82	M	H	0.0000
82A	N	H	-1.7869
82B	S	H	-1.4832
82C	L	H	0.0000
83	Q	H	-1.1874
84	I	H	0.4893
85	D	H	-1.2270
86	D	H	0.0000
87	T	H	-0.2507
88	A	H	0.0000
89	M	H	0.1191
90	Y	H	0.0000
91	Y	H	-0.0237
92	C	H	0.0000
93	A	H	0.0000
94	S	H	0.0000
95	R	H	-0.5763
96	G	H	-0.5490
97	G	H	-0.5996
98	H	H	-0.4795
99	Y	H	0.6261
100	G	H	0.4598
100A	Y	H	1.1310
100B	A	H	0.4497
100C	L	H	0.0382
101	D	H	-0.7531
102	Y	H	-0.3415
103	W	H	-0.2174
104	G	H	-0.8759
105	Q	H	-1.4675
106	G	H	-0.7925
107	T	H	-0.5716
108	S	H	-0.3710
109	V	H	0.0000
110	T	H	-0.0909
111	V	H	0.0000
112	S	H	0.1328
113	S	H	-0.0294
114	A	H	-0.3872
115	S	H	-0.6348
116	T	H	-0.9459
117	K	H	-1.6484
118	G	H	-1.6815
119	P	H	-0.8229
120	S	H	-0.3950
121	V	H	0.0000
122	Y	H	0.6098
123	P	H	-0.0197
124	L	H	0.5223
125	V	H	-0.3365
126	P	H	-0.4747
127	G	H	-0.4078
128	C	H	0.0025
131	T	H	-0.2732
132	S	H	-0.5531
133	G	H	-0.8176
134	S	H	-0.7067
135	S	H	-0.6613
136	V	H	0.0000
137	T	H	0.0033
138	L	H	0.0000
139	G	H	0.0000
140	C	H	0.0000
141	L	H	0.5978
142	V	H	0.0000
143	K	H	-0.3653
144	G	H	-0.8009
145	Y	H	0.0000
146	F	H	0.0000
147	P	H	0.0000
148	E	H	-0.4828
149	P	H	-0.4887
150	V	H	-0.2909
151	T	H	-0.4890
152	V	H	-0.4533
153	K	H	-0.6847
154	W	H	0.0000
155	N	H	-0.0677
156	Y	H	0.8663
157	G	H	-0.0272
158	A	H	0.1032
159	L	H	0.0289
160	S	H	-0.5105
161	S	H	-0.5645
162	G	H	-0.7355
163	V	H	-0.6580
164	R	H	-1.4792
165	T	H	-0.4748
166	V	H	0.4864
167	S	H	0.5572
168	S	H	1.0437
169	V	H	2.2727
170	L	H	1.7169
171	Q	H	-0.0343
172	S	H	-0.4647
173	G	H	-0.0125
174	F	H	0.3025
175	Y	H	0.6076
176	S	H	0.5095
177	L	H	0.7599
178	S	H	0.3632
179	S	H	0.0000
180	L	H	-0.1738
181	V	H	0.0000
182	T	H	-0.4146
183	V	H	0.0000
184	P	H	-0.6020
185	S	H	-0.6709
186	S	H	-0.7168
187	T	H	-0.7568
188	W	H	0.0000
189	P	H	-1.3105
190	S	H	-1.1888
191	Q	H	-1.4537
192	T	H	-1.4887
193	V	H	0.0000
194	I	H	0.0000
195	C	H	0.0000
196	N	H	0.0000
197	V	H	0.0000
198	A	H	-1.0544
199	H	H	0.0000
200	P	H	-1.3555
201	A	H	-1.1035
202	S	H	-1.6430
203	K	H	-2.2410
204	T	H	-1.9161
205	E	H	-1.9042
206	L	H	-0.4787
207	I	H	-0.0751
208	K	H	-1.0060
209	R	H	-2.3676
210	I	H	0.0000
211	E	H	-2.9082
212	P	H	-2.1371
213	R	H	-2.2324