Project name: 5c_KB

Chain sequence(s)	A: MLQALLTGSFLILFRLFPGQAQVPIQANFDASQFQGTWYVVGVASDDQSFLDSKDNMKMPVVLVTSLANGDLGLKFGYPTLDGRCQKMDMTFTKGATEGQFSNPAMAQTDIRVAFTDYQHFALLYFKTQKGDVQNIWLQLYARAPELFPEGAQKMQLLASQVGLSPSQGALLPKSGKGCPPSALQAC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7406
• Maximal score value: 3.1837
• Average score: -0.4661
• Total score value: -87.1696

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	2.7353
2	L	A	2.6429
3	Q	A	1.1412
4	A	A	1.7593
5	L	A	3.1837
6	L	A	2.7897
7	T	A	1.8084
8	G	A	2.2137
9	S	A	0.0000
10	F	A	2.5195
11	L	A	1.7540
12	I	A	2.0444
13	L	A	1.5362
14	F	A	2.1913
15	R	A	1.8275
16	L	A	1.8343
17	F	A	0.0000
18	P	A	0.0000
19	G	A	-0.1637
20	Q	A	0.0000
21	A	A	-0.4888
22	Q	A	-0.8296
23	V	A	0.0000
24	P	A	-0.2037
25	I	A	0.0608
26	Q	A	-0.2484
27	A	A	-0.6900
28	N	A	-1.6204
29	F	A	0.0000
30	D	A	-1.4635
31	A	A	-1.0994
32	S	A	-1.0809
33	Q	A	-1.9406
34	F	A	0.0000
35	Q	A	-1.0525
36	G	A	-0.7426
37	T	A	-0.0167
38	W	A	0.0000
39	Y	A	-0.1301
40	V	A	0.0000
41	V	A	0.0000
42	G	A	0.0000
43	V	A	0.0000
44	A	A	0.0000
45	S	A	0.0000
46	D	A	-1.2087
47	D	A	-1.4771
48	Q	A	-2.0715
49	S	A	-1.7745
50	F	A	-1.2051
51	L	A	-1.6710
52	D	A	-2.7406
53	S	A	-1.8327
54	K	A	-2.2780
55	D	A	0.0000
56	N	A	-1.5342
57	M	A	0.0000
58	K	A	-1.0819
59	M	A	0.0000
60	P	A	-0.4708
61	V	A	0.0000
62	V	A	0.0000
63	L	A	0.0188
64	V	A	0.0000
65	T	A	-0.3183
66	S	A	-0.2870
67	L	A	0.2564
68	A	A	-0.2754
69	N	A	-1.2753
70	G	A	-0.8002
71	D	A	-0.7543
72	L	A	0.0000
73	G	A	-0.4700
74	L	A	0.0000
75	K	A	-1.3809
76	F	A	0.0000
77	G	A	0.0000
78	Y	A	0.0000
79	P	A	-1.7939
80	T	A	-1.4605
81	L	A	-0.4818
82	D	A	-2.0230
83	G	A	-2.0038
84	R	A	-2.4762
85	C	A	-1.7491
86	Q	A	-1.8160
87	K	A	-2.4167
88	M	A	-1.8036
89	D	A	-2.2702
90	M	A	-1.0524
91	T	A	-0.5619
92	F	A	0.0000
93	T	A	-0.8745
94	K	A	-1.5260
95	G	A	-1.0198
96	A	A	-0.6295
97	T	A	-0.9574
98	E	A	-1.6867
99	G	A	0.0000
100	Q	A	-1.0780
101	F	A	0.0000
102	S	A	-0.8526
103	N	A	0.0000
104	P	A	-0.4896
105	A	A	0.0227
106	M	A	-0.0788
107	A	A	-1.1143
108	Q	A	-2.0268
109	T	A	0.0000
110	D	A	-1.0009
111	I	A	0.0000
112	R	A	-0.4738
113	V	A	0.0000
114	A	A	0.0000
115	F	A	0.6556
116	T	A	0.0000
117	D	A	-1.4172
118	Y	A	-1.3263
119	Q	A	-1.7415
120	H	A	-0.9454
121	F	A	-0.2630
122	A	A	0.0000
123	L	A	0.0000
124	L	A	0.0000
125	Y	A	0.0000
126	F	A	0.0000
127	K	A	-0.9330
128	T	A	0.0000
129	Q	A	-2.3964
130	K	A	-2.5766
131	G	A	-2.0616
132	D	A	-1.9253
133	V	A	-0.4463
134	Q	A	-1.1759
135	N	A	0.0000
136	I	A	0.0000
137	W	A	0.0000
138	L	A	0.0000
139	Q	A	0.0000
140	L	A	0.0000
141	Y	A	0.0000
142	A	A	0.0000
143	R	A	-0.9658
144	A	A	-0.8507
145	P	A	-1.1915
146	E	A	-1.6072
147	L	A	-0.1749
148	F	A	0.6746
149	P	A	-0.8492
150	E	A	-2.0110
151	G	A	-1.1394
152	A	A	-1.0795
153	Q	A	-2.0678
154	K	A	-1.5591
155	M	A	0.0000
156	Q	A	-1.3602
157	L	A	-0.2567
158	L	A	0.0000
159	A	A	0.0000
160	S	A	-0.1908
161	Q	A	-0.0256
162	V	A	0.0000
163	G	A	0.2709
164	L	A	0.0000
165	S	A	-0.6075
166	P	A	-0.6246
167	S	A	-0.7552
168	Q	A	-1.2071
169	G	A	-0.5022
170	A	A	-0.0342
171	L	A	0.8806
172	L	A	-0.4451
173	P	A	-1.3206
174	K	A	-2.1286
175	S	A	-1.5546
176	G	A	-1.8957
177	K	A	-2.4990
178	G	A	-1.8423
179	C	A	0.0000
180	P	A	-0.6373
181	P	A	-0.6468
182	S	A	-0.7608
183	A	A	-0.0987
184	L	A	0.6844
185	Q	A	-0.5363
186	A	A	-0.1511
187	C	A	0.5060