Project name: 5y9j:L

Chain sequence(s)	L: SELTQDPAVSVALGQTVRVTCQGDSLRSYYASWYQQKPGQAPVLVIYGKNNRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCSSRDSSGNHWVFGGGTELTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1841
• Maximal score value: 1.7565
• Average score: -0.8275
• Total score value: -173.7818

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	S	L	-1.2932
3	E	L	-1.9388
4	L	L	0.0000
5	T	L	-1.0549
6	Q	L	-1.3395
7	D	L	-2.2840
8	P	L	-1.6314
9	A	L	-1.1767
10	V	L	-0.6653
11	S	L	-0.0446
12	V	L	0.0000
13	A	L	0.1421
14	L	L	0.2092
15	G	L	-0.7607
16	Q	L	-1.1785
17	T	L	-1.1797
18	V	L	0.0000
19	R	L	-1.8609
20	V	L	0.0000
21	T	L	-1.0870
22	C	L	0.0000
23	Q	L	-1.7962
24	G	L	-1.8724
25	D	L	-2.0456
26	S	L	0.0000
27	L	L	0.0000
28	R	L	-2.3478
29	S	L	-1.1971
30	Y	L	-0.4033
31	Y	L	0.3606
32	A	L	0.0000
33	S	L	0.0000
34	W	L	0.0000
35	Y	L	0.8460
36	Q	L	-0.2215
37	Q	L	-1.0556
38	K	L	-1.8897
39	P	L	-1.4869
40	G	L	-1.4703
41	Q	L	-1.6036
42	A	L	-0.5851
43	P	L	0.0065
44	V	L	1.3638
45	L	L	1.1527
46	V	L	0.0000
47	I	L	0.0000
48	Y	L	-0.2653
49	G	L	-0.8818
50	K	L	-2.2778
51	N	L	-2.4462
52	N	L	-2.0901
53	R	L	-2.1018
54	P	L	-0.6528
55	S	L	-0.9380
56	G	L	-0.9111
57	I	L	-0.7473
58	P	L	-1.3594
59	D	L	-2.2599
60	R	L	-1.2875
61	F	L	0.0000
62	S	L	-1.5947
63	G	L	-1.3056
64	S	L	-0.8545
65	S	L	-1.0601
66	S	L	-1.0926
67	G	L	-1.6651
68	N	L	-1.8204
69	T	L	-1.1633
70	A	L	0.0000
71	S	L	-0.9100
72	L	L	0.0000
73	T	L	-0.9460
74	I	L	0.0000
75	T	L	-1.1502
76	G	L	-0.8064
77	A	L	0.0000
78	Q	L	-1.1506
79	A	L	-1.2023
80	E	L	-2.4025
81	D	L	0.0000
82	E	L	-1.3902
83	A	L	0.0000
84	D	L	-1.7115
85	Y	L	0.0000
86	Y	L	0.2417
87	C	L	0.0000
88	S	L	0.0000
89	S	L	0.0000
90	R	L	-1.5769
91	D	L	-1.7738
92	S	L	-1.6880
93	S	L	-1.2097
94	G	L	-1.4042
95	N	L	-2.0254
96	H	L	-1.5730
97	W	L	0.1582
98	V	L	0.2238
99	F	L	1.3334
100	G	L	0.0000
101	G	L	-0.8254
102	G	L	-0.9111
103	T	L	0.0000
104	E	L	-2.2030
105	L	L	0.0000
106	T	L	-0.1707
107	V	L	0.0000
108	L	L	0.8818
109	G	L	-0.0709
110	Q	L	-0.4652
111	P	L	-1.1247
112	K	L	-2.1533
113	A	L	-1.2428
114	A	L	-0.7668
115	P	L	0.0000
116	S	L	-0.3847
117	V	L	0.0000
118	T	L	0.2148
119	L	L	0.7616
120	F	L	1.7565
121	P	L	0.7422
122	P	L	0.0000
123	S	L	-1.0569
124	S	L	-1.8347
125	E	L	-2.8610
126	E	L	-2.4868
127	L	L	-2.4650
128	Q	L	-2.6453
129	A	L	-2.2246
130	N	L	-2.9575
131	K	L	-3.0904
132	A	L	0.0000
133	T	L	-0.1142
134	L	L	0.0000
135	V	L	1.1609
136	C	L	0.0000
137	L	L	0.9153
138	I	L	0.0000
139	S	L	-0.3805
140	D	L	-1.0592
141	F	L	0.0000
142	Y	L	-1.0061
143	P	L	-0.9101
144	G	L	-0.6185
145	A	L	-0.1997
146	V	L	-0.0986
147	T	L	-0.1197
148	V	L	-0.0443
149	A	L	-0.4694
150	W	L	0.0000
151	K	L	-0.9732
152	A	L	0.0000
153	D	L	-1.7421
154	S	L	-1.0797
155	S	L	-0.6875
156	P	L	-0.8769
157	V	L	-0.9188
158	K	L	-1.8669
159	A	L	-1.0600
160	G	L	-0.9924
161	V	L	-1.0802
162	E	L	-1.8412
163	T	L	-0.7461
164	T	L	-0.4678
165	T	L	-0.1366
166	P	L	-0.2671
167	S	L	-0.6116
168	K	L	-1.1335
169	Q	L	-1.2717
170	S	L	-1.5433
171	N	L	-2.0733
172	N	L	-1.7359
173	K	L	-1.4882
174	Y	L	-0.6945
175	A	L	-0.2939
176	A	L	-0.0197
177	S	L	0.0615
178	S	L	0.0000
179	Y	L	0.2530
180	L	L	0.0000
181	S	L	-0.7008
182	L	L	-1.1821
183	T	L	-1.9083
184	P	L	-2.5947
185	E	L	-3.1841
186	Q	L	-2.3034
187	W	L	0.0000
188	K	L	-3.0858
189	S	L	-2.4669
190	H	L	-2.4552
191	R	L	-2.5991
192	S	L	0.0000
193	Y	L	0.0000
194	S	L	0.0000
195	C	L	0.0000
196	Q	L	-0.9796
197	V	L	0.0000
198	T	L	-0.6898
199	H	L	0.0000
200	E	L	-2.2734
201	G	L	-1.4479
202	S	L	-0.8943
203	T	L	-0.7470
204	V	L	-0.7040
205	E	L	-1.8963
206	K	L	-1.4242
207	T	L	-0.7159
208	V	L	-0.0561
209	A	L	-0.8777
210	P	L	-1.0459
211	T	L	-0.6054