Project name: mab9

Chain sequence(s)	H: EVQLVQTGAEVKKPGSSVKVSCKASGGTFSTYGISWVRQAPGQGLEWIGGIIPIFDTGNSAQSFQGRVTITADESTSTAYMEVSSLRSQQTAVYYCASSSRIYDANRQAVPYYDMQVWGQGTMVTVS; L: AVLTQPSSVSTPPGQMVTISCSGSSSQIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAWVFGGGTKLTVLRT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1259
• Maximal score value: 1.8568
• Average score: -0.584
• Total score value: -138.9849

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.3533
2	V	H	0.2422
3	Q	H	-1.0087
4	L	H	0.0000
5	V	H	-0.3833
6	Q	H	0.0000
7	T	H	-0.7212
8	G	H	-0.6331
9	A	H	0.0188
10	E	H	-0.1795
11	V	H	0.8522
12	K	H	-0.9667
13	K	H	-2.1195
14	P	H	-1.9866
15	G	H	-1.5963
16	S	H	-1.2691
17	S	H	-1.5962
18	V	H	0.0000
19	K	H	-2.1133
20	V	H	0.0000
21	S	H	-0.7475
22	C	H	0.0000
23	K	H	-1.7207
24	A	H	0.0000
25	S	H	-0.9855
26	G	H	-1.0773
27	G	H	-1.0125
28	T	H	-0.8225
29	F	H	0.0000
30	S	H	0.0467
31	T	H	1.1377
32	Y	H	1.0013
33	G	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.4154
39	Q	H	-0.7334
40	A	H	0.0000
41	P	H	-1.0320
42	G	H	-1.2402
43	Q	H	-1.7660
44	G	H	-1.1797
45	L	H	0.0000
46	E	H	-0.6894
47	W	H	0.0000
48	I	H	0.0000
49	G	H	0.0000
50	G	H	-0.2698
51	I	H	0.0000
52	I	H	0.0000
52A	P	H	-0.2792
53	I	H	0.8805
54	F	H	0.9061
55	D	H	-1.2072
56	T	H	-0.6052
57	G	H	-0.7877
58	N	H	-0.9991
59	S	H	-1.2214
60	A	H	-1.0363
61	Q	H	-1.7332
62	S	H	-1.4311
63	F	H	0.0000
64	Q	H	-2.5278
65	G	H	-2.1335
66	R	H	-2.6351
67	V	H	-1.6970
68	T	H	-1.1441
69	I	H	-0.4716
70	T	H	-0.6304
71	A	H	-0.9561
72	D	H	-1.5831
73	E	H	-1.5317
74	S	H	-0.9970
75	T	H	-1.1410
76	S	H	0.0000
77	T	H	-1.1333
78	A	H	0.0000
79	Y	H	-0.5942
80	M	H	0.0000
81	E	H	-1.8418
82	V	H	0.0000
82A	S	H	-1.6313
82B	S	H	-1.4977
82C	L	H	0.0000
83	R	H	-2.8003
84	S	H	-2.0449
85	Q	H	-1.9288
86	Q	H	0.0000
87	T	H	-0.5740
88	A	H	0.0000
89	V	H	0.2268
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	S	H	0.0000
95	S	H	-0.0372
96	S	H	0.4966
97	R	H	0.0000
98	I	H	1.8568
99	Y	H	1.4491
100	D	H	-1.0779
100A	A	H	-1.0171
100B	N	H	-2.4595
100C	R	H	-3.1259
100D	Q	H	-2.4192
100E	A	H	-1.1946
100F	V	H	-0.7855
100G	P	H	0.0000
100H	Y	H	0.1226
100I	Y	H	0.3920
100J	D	H	0.0000
100K	M	H	0.0000
101	Q	H	-0.6137
102	V	H	-0.0470
103	W	H	-0.2341
104	G	H	0.0000
105	Q	H	-1.1136
106	G	H	-0.4796
107	T	H	0.0000
108	M	H	0.3592
109	V	H	0.0000
110	T	H	-0.1741
111	V	H	0.0000
112	S	H	-1.0674
2	A	L	0.0123
3	V	L	0.5356
4	L	L	0.0000
5	T	L	-0.2096
6	Q	L	-0.5797
7	P	L	-0.6471
8	S	L	-0.8784
10	S	L	-0.9685
11	V	L	-0.3547
12	S	L	-0.2441
13	T	L	0.0000
14	P	L	-0.7922
15	P	L	-1.2319
16	G	L	-1.2487
17	Q	L	-1.2069
18	M	L	0.0027
19	V	L	0.0000
20	T	L	0.0637
21	I	L	0.0000
22	S	L	-0.3717
23	C	L	0.0000
24	S	L	-0.3898
25	G	L	-0.3936
26	S	L	-0.6109
27	S	L	-0.9103
28	S	L	-0.6747
29	Q	L	-0.4603
30	I	L	0.0000
30A	G	L	-1.1985
30B	N	L	-1.4121
31	N	L	0.0000
32	Y	L	0.0803
33	V	L	0.0000
34	S	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	0.0000
39	L	L	-0.0263
40	P	L	-0.3136
41	G	L	-0.3651
42	T	L	-0.4659
43	A	L	-0.4838
44	P	L	0.0000
45	K	L	-1.1708
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-0.7329
50	D	L	-1.2119
51	N	L	-1.6241
52	N	L	-2.5846
53	K	L	-2.7395
54	R	L	-2.1988
55	P	L	0.0000
56	S	L	-0.6803
57	G	L	-0.8301
58	I	L	-1.0620
59	P	L	-1.3258
60	D	L	-2.1968
61	R	L	-1.2987
62	F	L	0.0000
63	S	L	-1.6072
64	G	L	-1.4364
65	S	L	-1.4048
66	K	L	-1.1883
67	S	L	-0.8681
68	G	L	-1.0791
69	T	L	-0.9579
70	S	L	-0.7228
71	A	L	0.0000
72	T	L	-0.6238
73	L	L	0.0000
74	G	L	-0.0904
75	I	L	0.0000
76	T	L	-0.7487
77	G	L	-1.0973
78	L	L	0.0000
79	Q	L	-1.9159
80	T	L	-1.3639
81	G	L	-1.1647
82	D	L	0.0000
83	E	L	-1.7806
84	A	L	0.0000
85	D	L	-1.1384
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	G	L	0.0000
90	T	L	0.0000
91	W	L	-0.0038
92	D	L	0.0000
93	S	L	-0.7628
94	S	L	-0.1693
95	L	L	0.1896
95A	S	L	-0.4798
95B	A	L	0.0000
96	W	L	0.0000
97	V	L	0.0000
98	F	L	0.0000
99	G	L	0.0000
100	G	L	-0.5752
101	G	L	-0.9927
102	T	L	0.0000
103	K	L	-2.1291
104	L	L	0.0000
105	T	L	-0.8536
106	V	L	0.0000
107	L	L	-0.0789
108	R	L	-1.4748
109	T	L	-0.7945