| Chain sequence(s) |
A: PVDDMSNLFYKTLLDDFSRSLEMQPLVFDDHGTCNMIIDNNTFALTLSCDYARERLLLIGLLEPHKDIPQQCCLLAGALNPLLNAGPGLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLEWMRGWREA B: LKANGQLEVDGKRYEIRAADDGTISVLRPEQQSKAKSFFKGASQLIGGSSQRAQIAQALNEKVASARTVLH |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| -2 | P | A | -0.3446 | |
| -1 | V | A | -0.2531 | |
| 0 | D | A | -1.0795 | |
| 1 | M | A | 0.1954 | |
| 2 | S | A | 0.0703 | |
| 3 | N | A | 0.0000 | |
| 4 | L | A | 0.2689 | |
| 5 | F | A | 0.7097 | |
| 6 | Y | A | 0.0000 | |
| 7 | K | A | -0.1714 | |
| 8 | T | A | -0.3385 | |
| 9 | L | A | 0.0000 | |
| 10 | L | A | 0.0000 | |
| 11 | D | A | -1.4658 | |
| 12 | D | A | -2.8650 | |
| 13 | F | A | 0.0000 | |
| 14 | S | A | 0.0000 | |
| 15 | R | A | -3.4387 | |
| 16 | S | A | -2.4327 | |
| 17 | L | A | 0.0000 | |
| 18 | E | A | -2.9572 | |
| 19 | M | A | 0.0000 | |
| 20 | Q | A | -1.1519 | |
| 21 | P | A | -0.9043 | |
| 22 | L | A | 0.0000 | |
| 23 | V | A | 1.1170 | |
| 24 | F | A | 0.0000 | |
| 25 | D | A | -1.3018 | |
| 26 | D | A | -2.0016 | |
| 27 | H | A | -1.7794 | |
| 28 | G | A | 0.0000 | |
| 29 | T | A | 0.0000 | |
| 30 | C | A | 0.0000 | |
| 31 | N | A | -0.6869 | |
| 32 | M | A | 0.0000 | |
| 33 | I | A | 0.0000 | |
| 34 | I | A | 0.0000 | |
| 35 | D | A | -1.6689 | |
| 36 | N | A | -1.0285 | |
| 37 | T | A | -0.8676 | |
| 38 | F | A | 0.0000 | |
| 39 | A | A | 0.0000 | |
| 40 | L | A | 0.0000 | |
| 41 | T | A | 0.0000 | |
| 42 | L | A | 0.0000 | |
| 43 | S | A | 0.0000 | |
| 44 | C | A | 0.0000 | |
| 45 | D | A | 0.0000 | |
| 46 | Y | A | 0.0000 | |
| 47 | A | A | -1.3477 | |
| 48 | R | A | -2.5061 | |
| 49 | E | A | -2.5009 | |
| 50 | R | A | -2.1920 | |
| 51 | L | A | 0.0000 | |
| 52 | L | A | 0.0529 | |
| 53 | L | A | 0.0000 | |
| 54 | I | A | 0.0000 | |
| 55 | G | A | 0.0000 | |
| 56 | L | A | 0.0000 | |
| 57 | L | A | 0.0000 | |
| 58 | E | A | -1.7989 | |
| 59 | P | A | -2.0328 | |
| 60 | H | A | -2.7599 | |
| 61 | K | A | -3.1102 | |
| 62 | D | A | -2.9468 | |
| 63 | I | A | -1.7837 | |
| 64 | P | A | -1.4443 | |
| 65 | Q | A | -1.2521 | |
| 66 | Q | A | -0.8720 | |
| 67 | C | A | -0.0457 | |
| 68 | L | A | 0.0000 | |
| 69 | L | A | 1.1768 | |
| 70 | A | A | 0.7572 | |
| 71 | G | A | 0.7668 | |
| 72 | A | A | 1.3252 | |
| 73 | L | A | 1.9180 | |
| 74 | N | A | 1.1881 | |
| 75 | P | A | 1.0687 | |
| 76 | L | A | 2.1608 | |
| 77 | L | A | 1.8484 | |
| 78 | N | A | 0.0074 | |
| 79 | A | A | 0.2893 | |
| 80 | G | A | 0.1151 | |
| 81 | P | A | 0.0846 | |
| 82 | G | A | 0.0000 | |
| 83 | L | A | 0.0000 | |
| 84 | G | A | 0.3404 | |
| 85 | L | A | -0.1076 | |
| 86 | D | A | -1.3049 | |
| 87 | E | A | -2.6901 | |
| 88 | K | A | -2.7336 | |
| 89 | S | A | -2.0482 | |
| 90 | G | A | -1.6315 | |
| 91 | L | A | 0.0000 | |
| 92 | Y | A | -0.1594 | |
| 93 | H | A | 0.1024 | |
| 94 | A | A | 0.0000 | |
| 95 | Y | A | 0.5677 | |
| 96 | Q | A | 0.0000 | |
| 97 | S | A | -0.1277 | |
| 98 | I | A | 0.0000 | |
| 99 | P | A | -2.1164 | |
| 100 | R | A | -2.3569 | |
| 101 | E | A | -3.0138 | |
| 102 | K | A | -2.7256 | |
| 103 | L | A | -1.3523 | |
| 104 | S | A | -1.0739 | |
| 105 | V | A | -0.6449 | |
| 106 | P | A | -0.8454 | |
| 107 | T | A | -1.0417 | |
| 108 | L | A | 0.0000 | |
| 109 | K | A | -1.5996 | |
| 110 | R | A | -2.3114 | |
| 111 | E | A | -1.2942 | |
| 112 | M | A | 0.0000 | |
| 113 | A | A | 0.0000 | |
| 114 | G | A | -1.1429 | |
| 115 | L | A | 0.0000 | |
| 116 | L | A | 0.0000 | |
| 117 | E | A | -0.9308 | |
| 118 | W | A | -0.4790 | |
| 119 | M | A | 0.0000 | |
| 120 | R | A | -1.7241 | |
| 121 | G | A | -1.5485 | |
| 122 | W | A | -1.3480 | |
| 123 | R | A | -1.9778 | |
| 124 | E | A | -2.4923 | |
| 125 | A | A | -1.3138 | |
| 24 | L | B | 0.4901 | |
| 25 | K | B | -1.0314 | |
| 26 | A | B | -0.9402 | |
| 27 | N | B | -1.3554 | |
| 28 | G | B | 0.0000 | |
| 29 | Q | B | -2.2221 | |
| 30 | L | B | 0.0000 | |
| 31 | E | B | -3.6621 | |
| 32 | V | B | -2.9698 | |
| 33 | D | B | -3.1823 | |
| 34 | G | B | -2.5544 | |
| 35 | K | B | -3.2082 | |
| 36 | R | B | -3.6943 | |
| 37 | Y | B | 0.0000 | |
| 38 | E | B | -1.9105 | |
| 39 | I | B | 0.0000 | |
| 40 | R | B | -1.2352 | |
| 41 | A | B | -0.7848 | |
| 42 | A | B | -1.6514 | |
| 43 | D | B | -2.9649 | |
| 44 | D | B | -2.8158 | |
| 45 | G | B | -1.5189 | |
| 46 | T | B | -0.9400 | |
| 47 | I | B | 0.0000 | |
| 48 | S | B | -0.7633 | |
| 49 | V | B | 0.6987 | |
| 50 | L | B | 0.0000 | |
| 51 | R | B | -2.3799 | |
| 52 | P | B | -1.9729 | |
| 53 | E | B | -2.9589 | |
| 54 | Q | B | -2.4668 | |
| 55 | Q | B | -2.0576 | |
| 56 | S | B | -2.1243 | |
| 57 | K | B | -2.6712 | |
| 58 | A | B | 0.0000 | |
| 59 | K | B | -2.8316 | |
| 60 | S | B | -2.0074 | |
| 61 | F | B | 0.0000 | |
| 62 | F | B | 0.0000 | |
| 63 | K | B | -2.3886 | |
| 64 | G | B | -1.5597 | |
| 65 | A | B | 0.0000 | |
| 66 | S | B | -0.9906 | |
| 67 | Q | B | -1.1376 | |
| 68 | L | B | -0.4441 | |
| 69 | I | B | -0.0915 | |
| 70 | G | B | -0.6862 | |
| 71 | G | B | -0.8880 | |
| 72 | S | B | -1.0394 | |
| 73 | S | B | -1.3292 | |
| 74 | Q | B | -1.7527 | |
| 75 | R | B | 0.0000 | |
| 76 | A | B | -1.7253 | |
| 77 | Q | B | -1.8488 | |
| 78 | I | B | -0.9367 | |
| 79 | A | B | 0.0000 | |
| 80 | Q | B | -2.2642 | |
| 81 | A | B | -1.5430 | |
| 82 | L | B | 0.0000 | |
| 83 | N | B | -1.8210 | |
| 84 | E | B | -2.6182 | |
| 85 | K | B | -1.8526 | |
| 86 | V | B | -1.3494 | |
| 87 | A | B | -1.3135 | |
| 88 | S | B | -0.8470 | |
| 89 | A | B | -0.5159 | |
| 90 | R | B | -1.1069 | |
| 91 | T | B | -0.0319 | |
| 92 | V | B | 1.5769 | |
| 93 | L | B | 1.2996 | |
| 94 | H | B | -0.1382 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine