| Chain sequence(s) |
A: GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFTYTDANKNKGITWKEETLMEYLENPKKYIPGTKMIFAGIKKKTEREDLIAYLKKATNEE B: GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFTYTDANKNKGITWKEETLMEYLENPKKYIPGTKMIFAGIKKKTEREDLIAYLKKATNE |
| Distance of aggregation | 5 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | G | A | -0.7921 | |
| 2 | D | A | -1.8108 | |
| 3 | V | A | -0.3077 | |
| 4 | E | A | -1.9684 | |
| 5 | K | A | -1.5133 | |
| 6 | G | A | 0.0000 | |
| 7 | K | A | -1.7664 | |
| 8 | K | A | -1.6140 | |
| 9 | I | A | 0.0000 | |
| 10 | F | A | 0.0000 | |
| 11 | V | A | 0.6248 | |
| 12 | Q | A | -1.1781 | |
| 13 | K | A | -1.2713 | |
| 14 | C | A | -0.1138 | |
| 15 | A | A | -0.0853 | |
| 16 | Q | A | -1.1737 | |
| 17 | C | A | -0.1119 | |
| 18 | H | A | 0.0000 | |
| 19 | T | A | -0.0245 | |
| 20 | V | A | 0.0000 | |
| 21 | E | A | -2.1554 | |
| 22 | K | A | -2.1335 | |
| 23 | G | A | -0.7994 | |
| 24 | G | A | -0.6972 | |
| 25 | K | A | -1.7828 | |
| 26 | H | A | -0.8189 | |
| 27 | K | A | -0.9011 | |
| 28 | T | A | -0.2129 | |
| 29 | G | A | -0.0494 | |
| 30 | P | A | -0.1079 | |
| 31 | N | A | -0.1010 | |
| 32 | L | A | 0.1287 | |
| 33 | H | A | -0.1677 | |
| 34 | G | A | -0.2226 | |
| 35 | L | A | 0.0000 | |
| 36 | F | A | 0.1638 | |
| 37 | G | A | -0.4802 | |
| 38 | R | A | -0.6088 | |
| 39 | K | A | -1.1689 | |
| 40 | T | A | 0.0000 | |
| 41 | G | A | -0.4830 | |
| 42 | Q | A | -1.1760 | |
| 43 | A | A | 0.0000 | |
| 44 | P | A | -0.3457 | |
| 45 | G | A | -0.4611 | |
| 46 | F | A | 0.1948 | |
| 47 | T | A | 0.0188 | |
| 48 | Y | A | 0.1787 | |
| 49 | T | A | -0.2878 | |
| 50 | D | A | -1.9564 | |
| 51 | A | A | -0.3222 | |
| 52 | N | A | -0.4422 | |
| 53 | K | A | -2.0869 | |
| 54 | N | A | -1.7312 | |
| 55 | K | A | -0.9777 | |
| 56 | G | A | -0.4872 | |
| 57 | I | A | 0.3322 | |
| 58 | T | A | -0.0933 | |
| 59 | W | A | 0.0000 | |
| 60 | K | A | -0.9458 | |
| 61 | E | A | -1.3041 | |
| 62 | E | A | -1.9700 | |
| 63 | T | A | -0.3549 | |
| 64 | L | A | 0.0000 | |
| 65 | M | A | -0.1928 | |
| 66 | E | A | -1.7688 | |
| 67 | Y | A | -0.1982 | |
| 68 | L | A | 0.0000 | |
| 69 | E | A | -1.1375 | |
| 70 | N | A | -0.5068 | |
| 71 | P | A | 0.0000 | |
| 72 | K | A | -2.0513 | |
| 73 | K | A | -2.0244 | |
| 74 | Y | A | 0.0000 | |
| 75 | I | A | 0.0000 | |
| 76 | P | A | -0.5198 | |
| 77 | G | A | -0.5147 | |
| 78 | T | A | -0.3836 | |
| 79 | K | A | -1.5134 | |
| 80 | M | A | 0.3291 | |
| 81 | I | A | 2.1281 | |
| 82 | F | A | 0.7686 | |
| 83 | A | A | 0.1300 | |
| 84 | G | A | 0.0000 | |
| 85 | I | A | 0.0000 | |
| 86 | K | A | -2.0034 | |
| 87 | K | A | -2.2862 | |
| 88 | K | A | -1.8571 | |
| 89 | T | A | -0.5896 | |
| 90 | E | A | -0.5752 | |
| 91 | R | A | 0.0000 | |
| 92 | E | A | -1.3586 | |
| 93 | D | A | 0.0000 | |
| 94 | L | A | 0.0000 | |
| 95 | I | A | 0.0000 | |
| 96 | A | A | 0.0091 | |
| 97 | Y | A | 0.0000 | |
| 98 | L | A | 0.0000 | |
| 99 | K | A | -1.1533 | |
| 100 | K | A | -1.4177 | |
| 101 | A | A | -0.2166 | |
| 102 | T | A | 0.0000 | |
| 103 | N | A | -1.4523 | |
| 104 | E | A | -2.0229 | |
| 1 | G | B | -0.8927 | |
| 2 | D | B | -1.7633 | |
| 3 | V | B | -0.0263 | |
| 4 | E | B | -2.1742 | |
| 5 | K | B | -2.0463 | |
| 6 | G | B | 0.0000 | |
| 7 | K | B | -1.5636 | |
| 8 | K | B | -1.7393 | |
| 9 | I | B | -0.0697 | |
| 10 | F | B | 0.0000 | |
| 11 | V | B | 1.5444 | |
| 12 | Q | B | -1.0461 | |
| 13 | K | B | -1.2273 | |
| 14 | C | B | -0.1146 | |
| 15 | A | B | 0.0080 | |
| 16 | Q | B | -1.1733 | |
| 17 | C | B | -0.1351 | |
| 18 | H | B | -0.1070 | |
| 19 | T | B | -0.0130 | |
| 20 | V | B | -0.1566 | |
| 21 | E | B | -2.0978 | |
| 22 | K | B | -2.1266 | |
| 23 | G | B | -0.8002 | |
| 24 | G | B | -0.4831 | |
| 25 | K | B | -1.7759 | |
| 26 | H | B | -0.9136 | |
| 27 | K | B | -1.4586 | |
| 28 | T | B | -0.3108 | |
| 29 | G | B | 0.0000 | |
| 30 | P | B | -0.0998 | |
| 31 | N | B | -0.1709 | |
| 32 | L | B | 0.1095 | |
| 33 | H | B | -0.2790 | |
| 34 | G | B | -0.3908 | |
| 35 | L | B | 0.1597 | |
| 36 | F | B | 0.2884 | |
| 37 | G | B | -0.7224 | |
| 38 | R | B | -2.1985 | |
| 39 | K | B | -1.7885 | |
| 40 | T | B | 0.0000 | |
| 41 | G | B | 0.0000 | |
| 42 | Q | B | -0.5640 | |
| 43 | A | B | -0.1390 | |
| 44 | P | B | -0.3381 | |
| 45 | G | B | -0.4452 | |
| 46 | F | B | 0.2719 | |
| 47 | T | B | 0.0775 | |
| 48 | Y | B | 0.1372 | |
| 49 | T | B | -0.3271 | |
| 50 | D | B | -2.0067 | |
| 51 | A | B | -0.4554 | |
| 52 | N | B | 0.0000 | |
| 53 | K | B | -2.1664 | |
| 54 | N | B | -1.6990 | |
| 55 | K | B | -0.9219 | |
| 56 | G | B | -0.5049 | |
| 57 | I | B | 0.1609 | |
| 58 | T | B | -0.1949 | |
| 59 | W | B | 0.0000 | |
| 60 | K | B | -1.1675 | |
| 61 | E | B | -1.5127 | |
| 62 | E | B | -1.9864 | |
| 63 | T | B | -0.3560 | |
| 64 | L | B | 0.0000 | |
| 65 | M | B | -0.3908 | |
| 66 | E | B | -1.7720 | |
| 67 | Y | B | -0.2106 | |
| 68 | L | B | 0.0000 | |
| 69 | E | B | -1.7083 | |
| 70 | N | B | -0.7654 | |
| 71 | P | B | 0.0000 | |
| 72 | K | B | -2.0397 | |
| 73 | K | B | -1.9779 | |
| 74 | Y | B | -0.1496 | |
| 75 | I | B | 0.0000 | |
| 76 | P | B | -0.5516 | |
| 77 | G | B | -0.5155 | |
| 78 | T | B | -0.3311 | |
| 79 | K | B | -1.2446 | |
| 80 | M | B | 0.3525 | |
| 81 | I | B | 2.1250 | |
| 82 | F | B | 0.7740 | |
| 83 | A | B | 0.1213 | |
| 84 | G | B | -0.3259 | |
| 85 | I | B | 0.0000 | |
| 86 | K | B | -2.0761 | |
| 87 | K | B | -1.8913 | |
| 88 | K | B | -1.9426 | |
| 89 | T | B | -0.5992 | |
| 90 | E | B | -0.6484 | |
| 91 | R | B | 0.0000 | |
| 92 | E | B | -0.8991 | |
| 93 | D | B | 0.0000 | |
| 94 | L | B | 0.0000 | |
| 95 | I | B | 0.0000 | |
| 96 | A | B | 0.0390 | |
| 97 | Y | B | 0.2551 | |
| 98 | L | B | 0.0000 | |
| 99 | K | B | -1.2886 | |
| 100 | K | B | -1.7207 | |
| 101 | A | B | -0.2788 | |
| 102 | T | B | 0.0000 | |
| 103 | N | B | -1.6054 | |
| 104 | E | B | -2.0524 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine