Project name: A1andG4

Chain sequence(s)	A: GQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSL; B: GNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLA
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.1328
• Maximal score value: 1.6761
• Average score: -0.3316
• Total score value: -71.6229

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	B	-0.6975
2	N	B	-1.3619
3	T	B	-0.1405
4	F	B	0.3093
5	R	B	-1.7246
6	P	B	0.0000
7	E	B	-0.9149
8	V	B	0.0000
9	H	B	0.0000
10	L	B	0.0000
11	L	B	0.0000
12	P	B	-0.0794
13	P	B	0.0000
14	P	B	-0.0630
15	S	B	-0.5420
16	E	B	-1.8579
17	E	B	0.0000
18	L	B	0.3348
19	A	B	0.1672
20	L	B	0.0585
21	N	B	-1.5567
22	E	B	-2.0079
23	L	B	-0.0668
24	V	B	0.0000
25	T	B	0.0000
26	L	B	0.0000
27	T	B	0.0000
28	C	B	0.0000
29	L	B	0.0000
30	A	B	0.0000
31	R	B	-0.2674
32	G	B	-0.1704
33	F	B	0.0000
34	S	B	0.0000
35	P	B	-0.3791
36	K	B	-2.0322
37	D	B	-2.0115
38	V	B	0.3899
39	L	B	1.6285
40	V	B	0.0000
41	R	B	-1.4587
42	W	B	0.0000
43	L	B	0.0000
44	Q	B	-0.2621
45	G	B	-0.5214
46	S	B	-0.5135
47	Q	B	-1.5715
48	E	B	-1.8280
49	L	B	0.8232
50	P	B	-0.0866
51	R	B	-0.6333
52	E	B	-2.0263
53	K	B	-1.1637
54	Y	B	0.1693
55	L	B	0.4208
56	T	B	0.0404
57	W	B	0.0000
58	A	B	0.0488
59	S	B	-0.1712
60	R	B	-0.8898
61	Q	B	-1.1203
62	E	B	0.0000
63	P	B	-0.3125
64	S	B	-0.4841
65	Q	B	-1.2638
66	G	B	-0.4019
67	T	B	-0.1044
68	T	B	-0.0501
69	T	B	0.0000
70	F	B	0.0000
71	A	B	0.0000
72	V	B	0.0000
73	T	B	0.0000
74	S	B	0.0000
75	I	B	0.0000
76	L	B	0.0000
77	R	B	0.0000
78	V	B	0.0000
79	A	B	0.0473
80	A	B	-0.3267
81	E	B	-1.9967
82	D	B	-0.8256
83	W	B	0.0000
84	K	B	-1.3196
85	K	B	-1.9099
86	G	B	-0.8094
87	D	B	-0.8992
88	T	B	-0.3351
89	F	B	0.0000
90	S	B	0.0000
91	C	B	0.0000
92	M	B	0.0731
93	V	B	0.0000
94	G	B	0.0000
95	H	B	0.0000
96	E	B	-1.8185
97	A	B	-0.5302
98	L	B	0.0000
99	P	B	0.0227
100	L	B	1.5094
101	A	B	0.5698
102	F	B	1.3594
103	T	B	0.1397
104	Q	B	-0.5684
105	K	B	-0.4975
106	T	B	-0.0901
107	I	B	0.0002
108	D	B	-1.4292
109	R	B	-0.9363
110	L	B	1.3713
111	A	B	0.3443
1	G	A	-0.6874
2	Q	A	-1.3048
3	P	A	-0.5330
4	R	A	-1.4172
5	E	A	-2.0238
6	P	A	0.0000
7	Q	A	-0.4476
8	V	A	0.0000
9	Y	A	0.0000
10	T	A	-0.0076
11	L	A	0.0000
12	P	A	-0.1929
13	P	A	-0.0640
14	S	A	0.0000
15	Q	A	-1.4738
16	E	A	-1.7410
17	E	A	0.0000
18	M	A	0.1710
19	T	A	-0.2220
20	K	A	-1.2531
21	N	A	-1.5614
22	Q	A	-1.0014
23	V	A	0.0000
24	S	A	0.0000
25	L	A	0.0000
26	T	A	0.0000
27	C	A	0.0000
28	L	A	0.0000
29	V	A	0.0000
30	K	A	0.0000
31	G	A	-0.0494
32	F	A	0.0000
33	Y	A	0.2276
34	P	A	0.0017
35	S	A	-0.4008
36	D	A	-1.7249
37	I	A	0.0807
38	A	A	0.1034
39	V	A	0.0000
40	E	A	-1.6919
41	W	A	0.0000
42	E	A	-0.5907
43	S	A	0.0000
44	N	A	-1.3562
45	G	A	-0.9130
46	Q	A	-1.3294
47	P	A	-0.5476
48	E	A	0.0000
49	N	A	-1.4512
50	N	A	-1.1688
51	Y	A	-0.0699
52	K	A	-0.5133
53	T	A	-0.1215
54	T	A	0.0000
55	P	A	-0.1800
56	P	A	0.0052
57	V	A	0.8038
58	L	A	1.6761
59	D	A	0.0000
60	S	A	-0.5325
61	D	A	-1.9098
62	G	A	-0.7826
63	S	A	0.0000
64	F	A	0.4402
65	F	A	0.0000
66	L	A	0.0000
67	Y	A	0.0000
68	S	A	0.0000
69	R	A	0.0000
70	L	A	0.0000
71	T	A	-0.0079
72	V	A	0.0000
73	D	A	-1.1831
74	K	A	-0.7025
75	S	A	-0.5315
76	R	A	-0.8439
77	W	A	0.0000
78	Q	A	-1.5475
79	E	A	-2.1328
80	G	A	-0.5867
81	N	A	-0.0643
82	V	A	1.5800
83	F	A	0.0000
84	S	A	0.0000
85	C	A	0.0000
86	S	A	0.0000
87	V	A	0.0000
88	M	A	0.3519
89	H	A	0.0000
90	E	A	-1.8186
91	A	A	-0.5050
92	L	A	-0.1406
93	H	A	-1.1880
94	N	A	-1.6278
95	H	A	-1.0700
96	Y	A	0.5442
97	T	A	0.0023
98	Q	A	-0.6843
99	K	A	-0.6830
100	S	A	-0.3131
101	L	A	0.0000
102	S	A	0.2450
103	L	A	0.5548
104	S	A	0.1763
105	L	A	1.5094