Project name: 3i9g:L
Status: done
submitted: 2019-03-20 20:10:37, status changed: 2019-03-20 20:24:37
Settings
|
Chain sequence(s)
|
L: ETTVTQSPSFLSASVGDRVTITCITTTDIDDDMNWFQQEPGKAPKLLISEGNILRPGVPSRFSSSGYGTDFTLTISKLQPEDFATYYCLQSDNLPFTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4647
-
Maximal score value
-
2.1116
-
Average score
-
-0.6858
-
Total score value
-
-146.069
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
L |
-1.3553 |
|
| 2 |
T |
L |
0.0000 |
|
| 3 |
T |
L |
0.0235 |
|
| 4 |
V |
L |
0.0000 |
|
| 5 |
T |
L |
-0.0429 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.2070 |
|
| 8 |
P |
L |
-0.1588 |
|
| 9 |
S |
L |
-0.2061 |
|
| 10 |
F |
L |
0.6186 |
|
| 11 |
L |
L |
0.3240 |
|
| 12 |
S |
L |
-0.3212 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-1.0664 |
|
| 15 |
V |
L |
-0.6209 |
|
| 16 |
G |
L |
-1.4047 |
|
| 17 |
D |
L |
-2.2258 |
|
| 18 |
R |
L |
-2.7224 |
|
| 19 |
V |
L |
-1.2156 |
|
| 20 |
T |
L |
-0.4067 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.3005 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
I |
L |
-0.1476 |
|
| 25 |
T |
L |
0.0000 |
|
| 26 |
T |
L |
-0.7762 |
|
| 27 |
T |
L |
-1.3804 |
|
| 28 |
D |
L |
-2.3766 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
D |
L |
-2.2789 |
|
| 31 |
D |
L |
-2.2727 |
|
| 32 |
D |
L |
-2.0142 |
|
| 33 |
M |
L |
0.0000 |
|
| 34 |
N |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
F |
L |
0.1732 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.5916 |
|
| 39 |
E |
L |
-2.3033 |
|
| 40 |
P |
L |
-1.7540 |
|
| 41 |
G |
L |
-1.6915 |
|
| 42 |
K |
L |
-2.5612 |
|
| 43 |
A |
L |
-1.4848 |
|
| 44 |
P |
L |
-1.3860 |
|
| 45 |
K |
L |
-1.4559 |
|
| 46 |
L |
L |
-0.0874 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
S |
L |
-0.1990 |
|
| 50 |
E |
L |
-1.5016 |
|
| 51 |
G |
L |
-0.9099 |
|
| 52 |
N |
L |
-0.4861 |
|
| 53 |
I |
L |
1.1548 |
|
| 54 |
L |
L |
0.6446 |
|
| 55 |
R |
L |
-0.1126 |
|
| 56 |
P |
L |
-0.3536 |
|
| 57 |
G |
L |
-0.6407 |
|
| 58 |
V |
L |
-0.4131 |
|
| 59 |
P |
L |
-0.4180 |
|
| 60 |
S |
L |
-0.5040 |
|
| 61 |
R |
L |
-1.2009 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.1931 |
|
| 64 |
S |
L |
-0.1920 |
|
| 65 |
S |
L |
-0.4599 |
|
| 66 |
G |
L |
-0.6084 |
|
| 67 |
Y |
L |
-0.4203 |
|
| 68 |
G |
L |
0.0000 |
|
| 69 |
T |
L |
-1.3291 |
|
| 70 |
D |
L |
-1.6934 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.3911 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.7259 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-2.0460 |
|
| 77 |
K |
L |
-2.6709 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.4853 |
|
| 80 |
P |
L |
-1.2599 |
|
| 81 |
E |
L |
-2.1131 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-0.5547 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.2452 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
L |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
S |
L |
-0.0404 |
|
| 92 |
D |
L |
-1.2407 |
|
| 93 |
N |
L |
-0.0128 |
|
| 94 |
L |
L |
1.3219 |
|
| 95 |
P |
L |
1.1348 |
|
| 96 |
F |
L |
2.1116 |
|
| 97 |
T |
L |
1.3065 |
|
| 98 |
F |
L |
1.8916 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-0.8499 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-0.4879 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
E |
L |
0.0000 |
|
| 106 |
I |
L |
-0.6814 |
|
| 107 |
K |
L |
-1.3760 |
|
| 108 |
R |
L |
-0.7715 |
|
| 109 |
T |
L |
0.2214 |
|
| 110 |
V |
L |
1.1323 |
|
| 111 |
A |
L |
0.3396 |
|
| 112 |
A |
L |
-0.0475 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1230 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.3878 |
|
| 117 |
I |
L |
1.3714 |
|
| 118 |
F |
L |
1.5729 |
|
| 119 |
P |
L |
0.1307 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.7476 |
|
| 122 |
D |
L |
-3.2527 |
|
| 123 |
E |
L |
-3.4647 |
|
| 124 |
Q |
L |
-2.5121 |
|
| 125 |
L |
L |
-2.5999 |
|
| 126 |
K |
L |
-3.0976 |
|
| 127 |
S |
L |
-1.9368 |
|
| 128 |
G |
L |
-1.3561 |
|
| 129 |
T |
L |
-1.1734 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0320 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7652 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.6066 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5952 |
|
| 138 |
N |
L |
-1.2434 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-0.9701 |
|
| 142 |
R |
L |
-1.4445 |
|
| 143 |
E |
L |
-2.1721 |
|
| 144 |
A |
L |
-1.6517 |
|
| 145 |
K |
L |
-1.9396 |
|
| 146 |
V |
L |
-1.0061 |
|
| 147 |
Q |
L |
-0.8416 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-1.0481 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.7113 |
|
| 152 |
N |
L |
-1.5697 |
|
| 153 |
A |
L |
-0.4669 |
|
| 154 |
L |
L |
0.2965 |
|
| 155 |
Q |
L |
-0.3944 |
|
| 156 |
S |
L |
-0.5542 |
|
| 157 |
G |
L |
-1.1160 |
|
| 158 |
N |
L |
-1.0552 |
|
| 159 |
S |
L |
-1.5025 |
|
| 160 |
Q |
L |
-2.2492 |
|
| 161 |
E |
L |
-1.9096 |
|
| 162 |
S |
L |
-0.5400 |
|
| 163 |
V |
L |
0.4928 |
|
| 164 |
T |
L |
-0.6162 |
|
| 165 |
E |
L |
-1.9704 |
|
| 166 |
Q |
L |
-1.8573 |
|
| 167 |
D |
L |
-2.4235 |
|
| 168 |
S |
L |
-2.1426 |
|
| 169 |
K |
L |
-2.4057 |
|
| 170 |
D |
L |
-1.8973 |
|
| 171 |
S |
L |
-1.9529 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.5535 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.1314 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5976 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.5614 |
|
| 181 |
L |
L |
-0.7273 |
|
| 182 |
S |
L |
-1.0663 |
|
| 183 |
K |
L |
-2.1022 |
|
| 184 |
A |
L |
-1.7940 |
|
| 185 |
D |
L |
-2.3861 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.2254 |
|
| 188 |
K |
L |
-3.3012 |
|
| 189 |
H |
L |
-2.3217 |
|
| 190 |
K |
L |
-2.0921 |
|
| 191 |
V |
L |
-0.6790 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
-0.7942 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-1.1416 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.0827 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.3684 |
|
| 200 |
G |
L |
-0.1738 |
|
| 201 |
L |
L |
-0.0914 |
|
| 202 |
S |
L |
-0.4322 |
|
| 203 |
S |
L |
-0.4026 |
|
| 204 |
P |
L |
-0.5186 |
|
| 205 |
V |
L |
-0.0693 |
|
| 206 |
T |
L |
-0.4703 |
|
| 207 |
K |
L |
-0.2327 |
|
| 208 |
S |
L |
-0.2058 |
|
| 209 |
F |
L |
-0.4628 |
|
| 210 |
N |
L |
-1.3766 |
|
| 211 |
R |
L |
-2.0325 |
|
| 212 |
G |
L |
-1.9050 |
|
| 213 |
E |
L |
-2.3503 |
|