Project name: 3iu3:H

Chain sequence(s)	H: QLQQSGTVLARPGASVKMSCKASGYSFTRYWMHWIKQRPGQGLEWIGAIYPGNSDTSYNQKFEGKAKLTAVTSASTAYMELSSLTHEDSAVYYCSRDYGYYFDFWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2239
• Maximal score value: 2.4852
• Average score: -0.525
• Total score value: -112.8735

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.3461
2	L	H	0.0000
3	Q	H	-2.0418
4	Q	H	0.0000
5	S	H	-1.0032
6	G	H	-0.6477
7	T	H	-0.0505
8	V	H	0.3939
9	L	H	0.5614
10	A	H	-0.6406
11	R	H	-2.0743
12	P	H	-1.6850
13	G	H	-1.2261
14	A	H	-0.9131
15	S	H	-1.1572
16	V	H	-1.0462
17	K	H	-2.1228
18	M	H	0.0000
19	S	H	-0.8946
20	C	H	0.0000
21	K	H	-1.2891
22	A	H	0.0000
23	S	H	-1.1212
24	G	H	-0.7919
25	Y	H	-0.5812
26	S	H	-0.7944
27	F	H	0.0000
28	T	H	-1.0310
29	R	H	-1.8216
30	Y	H	-0.3718
31	W	H	0.0467
32	M	H	0.0000
33	H	H	0.2508
34	W	H	0.0000
35	I	H	0.0000
36	K	H	0.0000
37	Q	H	-0.6736
38	R	H	-1.5147
39	P	H	-1.3704
40	G	H	-1.3042
41	Q	H	-1.7732
42	G	H	-0.8741
43	L	H	0.4593
44	E	H	-0.6695
45	W	H	0.0150
46	I	H	0.0000
47	G	H	0.0000
48	A	H	0.0000
49	I	H	0.0000
50	Y	H	-0.9222
51	P	H	0.0000
52	G	H	-1.6054
53	N	H	-2.2058
54	S	H	-1.5579
55	D	H	-2.2186
56	T	H	-1.2040
57	S	H	-0.7926
58	Y	H	-1.2052
59	N	H	-1.7460
60	Q	H	-2.6304
61	K	H	-2.9942
62	F	H	0.0000
63	E	H	-3.2239
64	G	H	-2.2459
65	K	H	-1.9505
66	A	H	0.0000
67	K	H	-2.4267
68	L	H	0.0000
69	T	H	-0.5988
70	A	H	0.3292
71	V	H	0.9623
72	T	H	0.1481
73	S	H	0.1090
74	A	H	0.0828
75	S	H	-0.0636
76	T	H	0.0000
77	A	H	0.0000
78	Y	H	-0.5254
79	M	H	0.0000
80	E	H	-2.0827
81	L	H	0.0000
82	S	H	-1.1474
83	S	H	-0.8437
84	L	H	0.0000
85	T	H	-1.5566
86	H	H	-2.1403
87	E	H	-2.3818
88	D	H	0.0000
89	S	H	-0.9096
90	A	H	0.0000
91	V	H	0.0188
92	Y	H	0.0000
93	Y	H	0.2322
94	C	H	0.0000
95	S	H	0.0000
96	R	H	0.0000
97	D	H	1.0989
98	Y	H	1.7053
99	G	H	1.1065
100	Y	H	2.0068
101	Y	H	2.2936
102	F	H	1.7472
103	D	H	1.1384
104	F	H	1.1848
105	W	H	0.4499
106	G	H	-0.7253
107	Q	H	-1.2626
108	G	H	-0.7327
109	T	H	0.0000
110	T	H	-0.1728
111	L	H	0.0000
112	T	H	-0.4328
113	V	H	0.0000
114	S	H	-1.1647
115	S	H	-1.0202
116	A	H	-0.5792
117	S	H	-0.6152
118	T	H	-0.5689
119	K	H	-1.1294
120	G	H	-1.4104
121	P	H	0.0000
122	S	H	-0.0783
123	V	H	0.0000
124	F	H	0.9787
125	P	H	0.0058
126	L	H	0.3422
127	A	H	-0.6242
128	P	H	0.0000
129	S	H	-1.0644
130	S	H	-1.2581
131	K	H	-1.9193
132	S	H	-1.0709
133	T	H	-1.0605
134	S	H	-0.9507
135	G	H	-0.9292
136	G	H	-0.9284
137	T	H	-0.6530
138	A	H	0.0000
139	A	H	-0.2283
140	L	H	0.0000
141	G	H	0.0000
142	C	H	0.0000
143	L	H	0.7827
144	V	H	0.0000
145	K	H	-0.2919
146	D	H	-0.6781
147	Y	H	0.0000
148	F	H	0.0000
149	P	H	0.0000
150	E	H	-1.1197
151	P	H	-1.1151
152	V	H	-0.6775
153	T	H	-0.7359
154	V	H	-0.3014
155	S	H	-0.4128
156	W	H	0.0000
157	N	H	-0.8767
158	S	H	-0.6916
159	G	H	-0.5925
160	A	H	-0.2668
161	L	H	-0.0785
162	T	H	-0.3072
163	S	H	-0.3968
164	G	H	-0.5105
165	V	H	-0.0452
166	H	H	-0.5140
167	T	H	0.2221
168	F	H	1.0884
169	P	H	0.7668
170	A	H	1.1873
171	V	H	2.4852
172	L	H	1.9885
173	Q	H	0.6338
174	S	H	0.0873
175	S	H	-0.2340
176	G	H	-0.0220
177	L	H	0.1425
178	Y	H	0.0000
179	S	H	0.6737
180	L	H	0.9931
181	S	H	0.7267
182	S	H	0.0000
183	V	H	0.4102
184	V	H	0.0000
185	T	H	-0.3407
186	V	H	0.0000
187	P	H	-0.5900
188	S	H	-0.6384
189	S	H	-0.6286
190	S	H	-0.5456
191	L	H	-0.6373
192	G	H	-0.7021
193	T	H	-0.6505
194	Q	H	-0.8859
195	T	H	-1.0595
196	Y	H	0.0000
197	I	H	-1.4904
198	C	H	0.0000
199	N	H	-1.5875
200	V	H	0.0000
201	N	H	-2.0246
202	H	H	0.0000
203	K	H	-2.7590
204	P	H	-1.6786
205	S	H	-1.7905
206	N	H	-2.4875
207	T	H	-2.0688
208	K	H	-2.6885
209	V	H	-1.5005
210	D	H	-2.7052
211	K	H	-2.1876
212	R	H	-2.8256
213	V	H	0.0000
214	E	H	-2.4358
215	P	H	-1.3627