Project name: 5l6y:L
Status: done
submitted: 2019-03-21 13:06:01, status changed: 2019-03-21 13:17:39
Settings
|
Chain sequence(s)
|
L: YVLTQPPSVSVAPGKTARITCGGNIIGSKLVHWYQQKPGQAPVLVIYDDGDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDTGSDPVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.2433
-
Maximal score value
-
1.8684
-
Average score
-
-0.7594
-
Total score value
-
-160.9984
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
Y |
L |
0.9701 |
|
| 3 |
V |
L |
1.7098 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
0.1973 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
P |
L |
-0.4261 |
|
| 8 |
P |
L |
-0.7237 |
|
| 9 |
S |
L |
-0.6335 |
|
| 11 |
V |
L |
-0.5244 |
|
| 12 |
S |
L |
-0.4035 |
|
| 13 |
V |
L |
0.0000 |
|
| 14 |
A |
L |
-1.1579 |
|
| 15 |
P |
L |
-1.7988 |
|
| 16 |
G |
L |
-2.3357 |
|
| 17 |
K |
L |
-2.9132 |
|
| 18 |
T |
L |
-2.1844 |
|
| 19 |
A |
L |
0.0000 |
|
| 20 |
R |
L |
-2.0464 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.5525 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
G |
L |
-0.3963 |
|
| 25 |
G |
L |
-0.2174 |
|
| 26 |
N |
L |
-0.5953 |
|
| 27 |
I |
L |
0.4806 |
|
| 28 |
I |
L |
0.0000 |
|
| 29 |
G |
L |
-0.4465 |
|
| 30 |
S |
L |
-0.0231 |
|
| 31 |
K |
L |
0.3619 |
|
| 32 |
L |
L |
0.7586 |
|
| 33 |
V |
L |
0.0000 |
|
| 34 |
H |
L |
-0.0110 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.7832 |
|
| 37 |
Q |
L |
-0.1724 |
|
| 38 |
Q |
L |
-0.9551 |
|
| 39 |
K |
L |
-1.4600 |
|
| 40 |
P |
L |
-1.3155 |
|
| 41 |
G |
L |
-1.3280 |
|
| 42 |
Q |
L |
-1.5641 |
|
| 43 |
A |
L |
-0.5131 |
|
| 44 |
P |
L |
0.0051 |
|
| 45 |
V |
L |
1.2501 |
|
| 46 |
L |
L |
1.1484 |
|
| 47 |
V |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.7965 |
|
| 50 |
D |
L |
-1.3832 |
|
| 51 |
D |
L |
-1.3352 |
|
| 52 |
G |
L |
-1.7085 |
|
| 53 |
D |
L |
-2.7405 |
|
| 54 |
R |
L |
-2.1605 |
|
| 55 |
P |
L |
-0.6783 |
|
| 56 |
S |
L |
-0.9590 |
|
| 57 |
G |
L |
-0.8205 |
|
| 58 |
I |
L |
-0.7234 |
|
| 59 |
P |
L |
-1.2779 |
|
| 60 |
E |
L |
-2.4008 |
|
| 61 |
R |
L |
-1.7849 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-1.4329 |
|
| 64 |
G |
L |
-1.2897 |
|
| 65 |
S |
L |
-0.9454 |
|
| 66 |
N |
L |
-0.7651 |
|
| 67 |
S |
L |
-0.8038 |
|
| 68 |
G |
L |
-0.9636 |
|
| 69 |
N |
L |
-1.4102 |
|
| 70 |
T |
L |
-0.9202 |
|
| 71 |
A |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7788 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.9716 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-2.3813 |
|
| 77 |
R |
L |
-3.0896 |
|
| 78 |
V |
L |
0.0000 |
|
| 79 |
E |
L |
-2.7502 |
|
| 80 |
A |
L |
-1.1764 |
|
| 81 |
G |
L |
-1.0607 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
E |
L |
-1.2230 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
D |
L |
-1.4574 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.2680 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
1.0923 |
|
| 90 |
V |
L |
0.0000 |
|
| 91 |
W |
L |
1.4310 |
|
| 92 |
D |
L |
0.2936 |
|
| 93 |
T |
L |
-0.3624 |
|
| 94 |
G |
L |
-0.8695 |
|
| 95 |
S |
L |
-1.1908 |
|
| 95A |
D |
L |
-1.2123 |
|
| 95B |
P |
L |
-0.4242 |
|
| 96 |
V |
L |
0.9487 |
|
| 97 |
V |
L |
0.0000 |
|
| 98 |
F |
L |
1.8684 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
G |
L |
-0.1351 |
|
| 101 |
G |
L |
-0.4890 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.3300 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
T |
L |
-0.4353 |
|
| 106 |
V |
L |
0.0000 |
|
| 107 |
L |
L |
-0.6587 |
|
| 109 |
G |
L |
-1.0029 |
|
| 110 |
Q |
L |
-1.2492 |
|
| 111 |
P |
L |
-1.2909 |
|
| 112 |
K |
L |
-2.2128 |
|
| 113 |
A |
L |
-1.3312 |
|
| 114 |
A |
L |
-0.7996 |
|
| 115 |
P |
L |
0.0000 |
|
| 116 |
S |
L |
-0.4770 |
|
| 117 |
V |
L |
0.0000 |
|
| 118 |
T |
L |
0.0771 |
|
| 119 |
L |
L |
0.0000 |
|
| 120 |
F |
L |
1.4604 |
|
| 121 |
P |
L |
0.5295 |
|
| 122 |
P |
L |
0.0000 |
|
| 123 |
S |
L |
-1.0245 |
|
| 124 |
S |
L |
-1.7529 |
|
| 125 |
E |
L |
-2.8921 |
|
| 126 |
E |
L |
-2.5505 |
|
| 127 |
L |
L |
-2.3881 |
|
| 128 |
Q |
L |
-2.6309 |
|
| 129 |
A |
L |
-2.2583 |
|
| 130 |
N |
L |
-2.9646 |
|
| 131 |
K |
L |
-3.1235 |
|
| 132 |
A |
L |
0.0000 |
|
| 133 |
T |
L |
-0.1385 |
|
| 134 |
L |
L |
0.0000 |
|
| 135 |
V |
L |
0.8846 |
|
| 136 |
C |
L |
0.0000 |
|
| 137 |
L |
L |
0.7921 |
|
| 138 |
I |
L |
0.0000 |
|
| 139 |
S |
L |
-0.5871 |
|
| 140 |
D |
L |
-1.4274 |
|
| 141 |
F |
L |
0.0000 |
|
| 142 |
Y |
L |
0.0000 |
|
| 143 |
P |
L |
0.0000 |
|
| 144 |
G |
L |
-0.8301 |
|
| 145 |
A |
L |
-0.1984 |
|
| 146 |
V |
L |
-0.0933 |
|
| 147 |
T |
L |
-0.1124 |
|
| 148 |
V |
L |
-0.0060 |
|
| 149 |
A |
L |
-0.4466 |
|
| 150 |
W |
L |
0.0000 |
|
| 151 |
K |
L |
-0.8897 |
|
| 152 |
A |
L |
0.0000 |
|
| 153 |
D |
L |
-1.2668 |
|
| 154 |
S |
L |
-0.8413 |
|
| 155 |
S |
L |
-0.7745 |
|
| 156 |
P |
L |
-0.8666 |
|
| 157 |
V |
L |
-0.8245 |
|
| 158 |
K |
L |
-1.8391 |
|
| 159 |
A |
L |
-1.0531 |
|
| 160 |
G |
L |
-0.9215 |
|
| 161 |
V |
L |
-0.8709 |
|
| 162 |
E |
L |
-1.6696 |
|
| 163 |
T |
L |
-0.6074 |
|
| 164 |
T |
L |
-0.4758 |
|
| 165 |
T |
L |
-0.2956 |
|
| 166 |
P |
L |
-0.5706 |
|
| 167 |
S |
L |
-1.2745 |
|
| 168 |
K |
L |
-2.6246 |
|
| 169 |
Q |
L |
-2.2395 |
|
| 170 |
S |
L |
-1.7853 |
|
| 171 |
N |
L |
-2.5337 |
|
| 172 |
N |
L |
-2.8102 |
|
| 173 |
K |
L |
-2.4171 |
|
| 174 |
Y |
L |
-1.5896 |
|
| 175 |
A |
L |
-0.8365 |
|
| 176 |
A |
L |
0.0000 |
|
| 177 |
S |
L |
0.0224 |
|
| 178 |
S |
L |
0.0000 |
|
| 179 |
Y |
L |
0.3689 |
|
| 180 |
L |
L |
0.0000 |
|
| 181 |
S |
L |
-0.6667 |
|
| 182 |
L |
L |
0.0000 |
|
| 183 |
T |
L |
-1.9410 |
|
| 184 |
P |
L |
0.0000 |
|
| 185 |
E |
L |
-3.2433 |
|
| 186 |
Q |
L |
-2.3828 |
|
| 187 |
W |
L |
0.0000 |
|
| 188 |
K |
L |
-3.1217 |
|
| 189 |
S |
L |
-2.4413 |
|
| 190 |
H |
L |
-2.3559 |
|
| 191 |
R |
L |
-2.6996 |
|
| 192 |
S |
L |
-1.6413 |
|
| 193 |
Y |
L |
0.0000 |
|
| 194 |
S |
L |
-0.9508 |
|
| 195 |
C |
L |
0.0000 |
|
| 196 |
Q |
L |
-0.9778 |
|
| 197 |
V |
L |
0.0000 |
|
| 198 |
T |
L |
-0.6822 |
|
| 199 |
H |
L |
0.0000 |
|
| 200 |
E |
L |
-2.3002 |
|
| 201 |
G |
L |
-1.4274 |
|
| 202 |
S |
L |
-0.8806 |
|
| 203 |
T |
L |
-0.7077 |
|
| 204 |
V |
L |
-0.6352 |
|
| 205 |
E |
L |
-1.7677 |
|
| 206 |
K |
L |
-1.4396 |
|
| 207 |
T |
L |
-0.7568 |
|
| 208 |
V |
L |
0.0000 |
|
| 209 |
A |
L |
-1.3032 |
|
| 210 |
P |
L |
-1.4552 |
|
| 211 |
T |
L |
-1.4739 |
|
| 212 |
E |
L |
-1.7121 |
|
| 213 |
C |
L |
-0.0754 |
|