Project name: FGF

Chain sequence(s)	A: PALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGPKTGPGQKAILFLPMSAKSHHHHHH
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:03:46)
[INFO]       Main:     Simulation completed successfully.                                          (00:03:47)

• Minimal score value: -3.6435
• Maximal score value: 1.4709
• Average score: -0.9927
• Total score value: -150.8961

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	P	A	0.1214
2	A	A	0.3757
3	L	A	0.7285
4	P	A	-0.9760
5	E	A	-2.6060
6	D	A	-2.9035
7	G	A	-2.2463
8	G	A	-1.5940
9	S	A	-0.6417
10	G	A	-0.1684
11	A	A	0.5015
12	F	A	1.4709
13	P	A	0.5447
14	P	A	0.0542
15	G	A	0.0000
16	H	A	-0.6280
17	F	A	0.2970
18	K	A	-1.4772
19	D	A	-1.3822
20	P	A	-1.2359
21	K	A	-1.0129
22	R	A	-0.9905
23	L	A	0.0000
24	Y	A	-0.2557
25	C	A	0.0000
26	K	A	-1.4796
27	N	A	0.0000
28	G	A	-1.6830
29	G	A	-1.1247
30	F	A	0.0000
31	F	A	0.0000
32	L	A	0.0000
33	R	A	-1.1723
34	I	A	0.0000
35	H	A	-1.7539
36	P	A	-1.9131
37	D	A	-2.6956
38	G	A	-2.2762
39	R	A	-2.6084
40	V	A	0.0000
41	D	A	-1.2361
42	G	A	-1.3989
43	V	A	-1.8608
44	R	A	-3.1743
45	E	A	-3.6435
46	K	A	-3.3321
47	S	A	-2.1114
48	D	A	-1.8920
49	P	A	-0.8468
50	H	A	-0.6745
51	I	A	0.0000
52	K	A	-1.0773
53	L	A	0.0000
54	Q	A	-0.8115
55	L	A	-0.6964
56	Q	A	-1.2455
57	A	A	-1.5406
58	E	A	-2.0159
59	E	A	-3.1285
60	R	A	-3.0120
61	G	A	-1.8291
62	V	A	0.0000
63	V	A	0.0000
64	S	A	0.0000
65	I	A	0.0000
66	K	A	-0.8208
67	G	A	0.0000
68	V	A	0.3000
69	C	A	0.3142
70	A	A	-1.0101
71	N	A	-1.4191
72	R	A	-1.4119
73	Y	A	-0.3878
74	L	A	0.0000
75	A	A	0.0000
76	M	A	0.0000
77	K	A	-2.8335
78	E	A	-3.3199
79	D	A	-2.7132
80	G	A	0.0000
81	R	A	-2.5903
82	L	A	0.0000
83	L	A	-1.0849
84	A	A	0.0000
85	S	A	-1.1023
86	K	A	-1.7957
87	C	A	0.1154
88	V	A	0.7855
89	T	A	0.0242
90	D	A	-1.1531
91	E	A	-1.3586
92	C	A	0.0000
93	F	A	-0.8044
94	F	A	0.0000
95	F	A	-1.0780
96	E	A	-0.9323
97	R	A	-0.7939
98	L	A	0.1734
99	E	A	-0.9816
100	S	A	-1.0398
101	N	A	-1.4124
102	N	A	-1.5079
103	Y	A	-0.8146
104	N	A	-0.4004
105	T	A	0.0000
106	Y	A	0.0000
107	R	A	-1.0904
108	S	A	0.0000
109	R	A	-1.4743
110	K	A	-2.2949
111	Y	A	-1.3708
112	S	A	-0.8772
113	S	A	-0.8268
114	W	A	-0.7325
115	Y	A	0.0000
116	V	A	0.0000
117	A	A	0.0000
118	L	A	0.0000
119	K	A	-2.5048
120	R	A	-2.8497
121	T	A	-1.7051
122	G	A	0.0000
123	Q	A	-1.8605
124	Y	A	-1.4865
125	K	A	-1.4667
126	L	A	-1.2952
127	G	A	0.0000
128	P	A	-1.3990
129	K	A	-1.6898
130	T	A	0.0000
131	G	A	-1.0099
132	P	A	-0.8509
133	G	A	-1.0413
134	Q	A	-1.4006
135	K	A	-1.9436
136	A	A	0.0000
137	I	A	0.0000
138	L	A	0.0000
139	F	A	0.0000
140	L	A	0.1022
141	P	A	-0.0227
142	M	A	-0.1973
143	S	A	-1.0818
144	A	A	-1.7697
145	K	A	-2.4920
146	S	A	-2.0318
147	H	A	-2.5278
148	H	A	-2.7336
149	H	A	-2.7130
150	H	A	-2.6702
151	H	A	-2.3911
152	H	A	-1.8846