Project name: 225dd99161e65c2

Chain sequence(s)	L: CFYQCKKHC
Selected Chain(s)	L
Distance of aggregation	5 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with L chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:09)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:10)

• Minimal score value: -2.0626
• Maximal score value: 2.3912
• Average score: 0.084
• Total score value: 0.7556

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
446	C	L	0.9756
447	F	L	2.3912
448	Y	L	1.4492
449	Q	L	-0.8309
450	C	L	0.5499
451	K	L	-1.1048
452	K	L	-2.0626
453	H	L	-1.1656
454	C	L	0.5536