Project name: TGF

Chain sequence(s)	A: ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCSHHHHHH
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:13)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:14)

• Minimal score value: -3.6044
• Maximal score value: 3.0436
• Average score: -0.4798
• Total score value: -56.6202

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	0.4376
2	L	A	1.1287
3	D	A	-0.5963
4	T	A	-0.2005
5	N	A	-0.9453
6	Y	A	-0.3654
7	C	A	0.0000
8	F	A	1.2519
9	S	A	-0.0114
10	S	A	-0.6831
11	T	A	-1.2225
12	E	A	-2.1881
13	K	A	-2.5387
14	N	A	-1.3406
15	C	A	-0.0719
16	C	A	-0.0414
17	V	A	0.0000
18	R	A	0.0021
19	Q	A	-0.5044
20	L	A	0.3952
21	Y	A	0.4875
22	I	A	-0.5076
23	D	A	0.0000
24	F	A	0.0000
25	R	A	-3.6044
26	K	A	-3.4230
27	D	A	-2.1833
28	L	A	-1.1346
29	G	A	-1.7188
30	W	A	-1.5283
31	K	A	-2.1588
32	W	A	-0.1548
33	I	A	0.0000
34	H	A	-2.2455
35	E	A	-2.4020
36	P	A	-2.1728
37	K	A	-3.2101
38	G	A	0.0000
39	Y	A	0.0000
40	H	A	-0.4522
41	A	A	0.0000
42	N	A	0.0000
43	F	A	0.7319
44	C	A	0.7003
45	L	A	1.2864
46	G	A	-0.1929
47	P	A	-0.3400
48	C	A	0.6519
49	P	A	0.9334
50	Y	A	2.2014
51	I	A	3.0436
52	W	A	2.2805
53	S	A	0.0000
54	L	A	1.5514
55	D	A	-0.5221
56	T	A	-0.2145
57	Q	A	-0.3919
58	Y	A	0.9953
59	S	A	0.0000
60	K	A	1.0815
61	V	A	2.0323
62	L	A	1.2799
63	A	A	0.0000
64	L	A	1.5200
65	Y	A	1.1045
66	N	A	-0.3700
67	Q	A	-1.1188
68	H	A	-1.4578
69	N	A	-1.4193
70	P	A	-1.2825
71	G	A	-1.1450
72	A	A	-0.7069
73	S	A	-0.4343
74	A	A	-0.1403
75	A	A	0.0359
76	P	A	0.1295
77	C	A	0.6147
78	C	A	0.8215
79	V	A	0.4205
80	P	A	-0.4486
81	Q	A	-1.5559
82	A	A	-1.2406
83	L	A	-1.0329
84	E	A	-1.5266
85	P	A	-1.4232
86	L	A	0.0000
87	P	A	-0.9207
88	I	A	0.0000
89	V	A	-0.2882
90	Y	A	-0.1186
91	Y	A	0.7309
92	V	A	0.8797
93	G	A	-0.7317
94	R	A	-2.2654
95	K	A	-2.1260
96	P	A	-0.6817
97	K	A	-0.2555
98	V	A	0.6274
99	E	A	-0.8531
100	Q	A	-1.5542
101	L	A	-0.9651
102	S	A	-1.2397
103	N	A	-1.6021
104	M	A	-0.9311
105	I	A	-0.5832
106	V	A	0.0000
107	R	A	-2.2592
108	S	A	-1.2976
109	C	A	-0.4286
110	K	A	-0.0803
111	C	A	0.0000
112	S	A	-0.2243
113	H	A	-0.8123
114	H	A	-1.8221
115	H	A	-2.4544
116	H	A	-2.5702
117	H	A	-2.4299
118	H	A	-1.9125