Project name: d11badf653310c

Chain sequence(s)	H: VQLVESGGGLVEPGGSLRLSCAASGFTFSNSDMNWVRQAPGKGLEWVSGVSWNGSRTHYADSVKGRFIISRDNSRNFLYQQMNSLRPEDMAVYYCVKVVTTEWGQGTLVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:04)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:04)

• Minimal score value: -2.5708
• Maximal score value: 1.7532
• Average score: -0.5213
• Total score value: -58.9053

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
0	V	H	1.4884
1	Q	H	-0.0402
2	L	H	0.0000
3	V	H	0.5592
4	E	H	0.0857
5	S	H	-0.3971
6	G	H	-0.7487
7	G	H	-0.1729
8	G	H	0.4440
9	L	H	1.1181
10	V	H	0.0000
11	E	H	-1.9923
12	P	H	-1.8848
13	G	H	-1.5949
14	G	H	-1.3703
15	S	H	-1.4041
16	L	H	-1.2488
17	R	H	-2.0863
18	L	H	0.0000
19	S	H	-0.4714
20	C	H	0.0000
21	A	H	-0.1450
22	A	H	0.0753
23	S	H	0.2487
24	G	H	0.8171
25	F	H	1.7532
26	T	H	0.4248
27	F	H	0.0000
28	S	H	-1.1307
29	N	H	-1.1237
30	S	H	0.0000
31	D	H	-0.4340
32	M	H	0.0000
33	N	H	0.0712
34	W	H	0.0000
35	V	H	0.0000
36	R	H	0.0000
37	Q	H	-0.3830
38	A	H	-0.9805
39	P	H	-0.8177
40	G	H	-1.4311
41	K	H	-2.0990
42	G	H	-0.9889
43	L	H	0.5117
44	E	H	-0.1875
45	W	H	0.5177
46	V	H	0.0000
47	S	H	0.0000
48	G	H	0.0000
49	V	H	0.0000
50	S	H	-1.1941
51	W	H	-0.7605
52	N	H	-1.5423
53	G	H	-1.4463
54	S	H	-1.3624
55	R	H	-2.2881
56	T	H	-1.3909
57	H	H	-1.6299
58	Y	H	-1.1379
59	A	H	-1.5316
60	D	H	-2.5708
61	S	H	-1.7801
62	V	H	0.0000
63	K	H	-2.5569
64	G	H	-1.5676
65	R	H	-1.2923
66	F	H	0.0000
67	I	H	0.3601
68	I	H	0.0000
69	S	H	-0.5366
70	R	H	-1.2224
71	D	H	-1.9921
72	N	H	-1.9828
73	S	H	-1.7703
74	R	H	-2.5262
75	N	H	-1.4440
76	F	H	-0.8887
77	L	H	0.0000
78	Y	H	-0.4373
79	Q	H	0.0000
80	Q	H	-0.9996
81	M	H	0.0000
82	N	H	-1.6270
83	S	H	-1.4071
84	L	H	0.0000
85	R	H	-2.2194
86	P	H	-1.8791
87	E	H	-2.1744
88	D	H	0.0000
89	M	H	-0.2520
90	A	H	0.0000
91	V	H	0.7223
92	Y	H	0.0000
93	Y	H	0.4071
94	C	H	0.0000
95	V	H	0.0000
96	K	H	0.0000
97	V	H	0.5588
98	V	H	1.5931
99	T	H	0.5708
100	T	H	0.5767
101	E	H	0.2738
102	W	H	0.2757
103	G	H	-0.2006
104	Q	H	-1.0208
105	G	H	-0.1544
106	T	H	0.2250
107	L	H	1.1430
108	V	H	0.0000
109	T	H	0.1447
110	V	H	0.0000
111	S	H	-1.0757
112	S	H	-0.8764