Project name: FGF2

Chain sequence(s)	A: MAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:03:30)
[INFO]       Main:     Simulation completed successfully.                                          (00:03:31)

• Minimal score value: -3.6362
• Maximal score value: 1.9352
• Average score: -0.8212
• Total score value: -127.2866

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	1.0406
2	A	A	0.4472
3	A	A	0.3318
4	G	A	0.1417
5	S	A	0.5320
6	I	A	1.9352
7	T	A	1.1467
8	T	A	1.1343
9	L	A	1.8680
10	P	A	0.8715
11	A	A	0.7359
12	L	A	0.8356
13	P	A	-1.0481
14	E	A	-2.6168
15	D	A	-2.9369
16	G	A	-2.3509
17	G	A	-1.8058
18	S	A	-0.7803
19	G	A	-0.2387
20	A	A	0.5248
21	F	A	1.5050
22	P	A	0.3653
23	P	A	0.1349
24	G	A	-0.5312
25	H	A	-1.0369
26	F	A	-0.0176
27	K	A	-2.0829
28	D	A	-2.7540
29	P	A	-1.7037
30	K	A	-1.1095
31	R	A	-0.8367
32	L	A	0.0000
33	Y	A	-0.1865
34	C	A	0.0000
35	K	A	-1.0387
36	N	A	0.0000
37	G	A	-1.5413
38	G	A	-1.1802
39	F	A	0.0000
40	F	A	0.0000
41	L	A	0.0000
42	R	A	-1.0516
43	I	A	0.0000
44	H	A	-1.6104
45	P	A	-1.8788
46	D	A	-2.6592
47	G	A	0.0000
48	R	A	-2.4299
49	V	A	0.0000
50	D	A	-1.0722
51	G	A	-1.2817
52	V	A	-1.8330
53	R	A	-3.1626
54	E	A	-3.6362
55	K	A	-3.3016
56	S	A	-2.0722
57	D	A	-1.8962
58	P	A	-0.8362
59	H	A	-0.6588
60	I	A	0.0000
61	K	A	-1.0677
62	L	A	0.0000
63	Q	A	-1.0003
64	L	A	-0.8464
65	Q	A	-1.4001
66	A	A	-1.8765
67	E	A	-2.9227
68	E	A	-3.1200
69	R	A	-2.9610
70	G	A	-1.8695
71	V	A	0.0000
72	V	A	0.0000
73	S	A	0.0000
74	I	A	0.0000
75	K	A	-0.6327
76	G	A	0.0000
77	V	A	0.2567
78	C	A	0.2841
79	A	A	-1.2597
80	N	A	-1.4508
81	R	A	-1.5407
82	Y	A	-0.2869
83	L	A	0.0000
84	A	A	0.0000
85	M	A	0.0000
86	K	A	-2.5115
87	E	A	-3.3240
88	D	A	-2.9696
89	G	A	0.0000
90	R	A	-2.3804
91	L	A	0.0000
92	L	A	-0.9047
93	A	A	0.0000
94	S	A	-1.0358
95	K	A	-1.7552
96	C	A	0.2952
97	V	A	0.8554
98	T	A	-0.0627
99	D	A	-1.4970
100	E	A	-1.4458
101	C	A	0.0000
102	F	A	0.0000
103	F	A	0.0000
104	F	A	-1.1613
105	E	A	-1.0024
106	R	A	-0.8912
107	L	A	0.0696
108	E	A	-1.1649
109	S	A	-1.2867
110	N	A	-1.8531
111	N	A	-1.6949
112	Y	A	-0.8496
113	N	A	-0.4151
114	T	A	0.0000
115	Y	A	0.0000
116	R	A	-0.8793
117	S	A	0.0000
118	R	A	-1.5989
119	K	A	-2.4537
120	Y	A	-1.4918
121	T	A	-0.7176
122	S	A	-0.6962
123	W	A	-0.5832
124	Y	A	-0.3413
125	V	A	0.0000
126	A	A	0.0000
127	L	A	0.0000
128	K	A	-1.9982
129	R	A	-2.5845
130	T	A	-1.4452
131	G	A	0.0000
132	Q	A	-1.3817
133	Y	A	-1.2320
134	K	A	-1.3772
135	L	A	-1.3957
136	G	A	0.0000
137	S	A	-1.6855
138	K	A	-1.8107
139	T	A	-1.2038
140	G	A	-0.9284
141	P	A	-0.7652
142	G	A	-1.0033
143	Q	A	-1.3578
144	K	A	-1.7460
145	A	A	0.0000
146	I	A	0.0000
147	L	A	-0.5846
148	F	A	0.0000
149	L	A	0.3831
150	P	A	0.1669
151	M	A	-0.1406
152	S	A	-1.0533
153	A	A	-1.7909
154	K	A	-2.1516
155	S	A	-1.1317