CABS-dock: ASIC

Project name: ASIC_A-O

Status: done

submitted: 2025-12-31 20:20:06, status changed: 2026-01-01 10:15:22

Project settings

Protein sequence(s)

LCFLGSLAVLLCVCTERVQYYFHYHHVTKLDEVAASQLTFPAVTLCNLNEFRFSQVSKNDLYHAGELLALLNNRYEIPDTQMADEKQLEILQDKANFRSFKPKPFNMREFYDRAGHDIRDMLLSCHFRGEVCSAEDFKVVFTRYGKCYTFNSGRDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVACQEQRLIYLPPPWGTCKAVTMDSDLDFFDSYSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKECADPALDFLVEKDQEYCVCEMPCNLTRYGKELSMVKIPSKASAKYLAKKFNKSEQYIGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHKL input pdb

Peptide sequence

QIRPAFCYEDPPFFQKCGAFVDSYYFNRSR

Simulation mc cycles

Peptide secondary structure

CCCCHHHHCCCCCCCCCCCCEEEEEEECCC

Flexible regions

364:A - 364:A

287:A - 287:A

Contact information

287:A 20:PEP 5.0 0.8

364:A 13:PEP 5.0 1.2

Re-submit project

Zoom/rotate predicted model of the complex using mouse. Click the "View" button on the right panel to load the appropriate model. View in JSmol (pure html5/js) if you got rendering problems.

Models are ranked and numbered according to their occurrence in docking trajectory (1 = most probable result).

Representative conformations

	model_1		Download
	model_2		Download
	model_3		Download
	model_4		Download
	model_5		Download
	model_6		Download
	model_7		Download
	model_8		Download
	model_9		Download
	model_10		Download

Download all files

Click the "View" button to load the contact map of appropriate model.

Representative conformations

Contact cutoff (Å)

	model_1	View
	model_2	View
	model_3	View
	model_4	View
	model_5	View
	model_6	View
	model_7	View
	model_8	View
	model_9	View
	model_10	View

Receptor residue	Peptide residue

Receptor residue	Peptide residue

Receptor residue	Peptide residue

Select trajectory from the right panel to display animation in JSmol. Note that it may hangs browser window for few minutes or ever.

Trajectories

	replica_1		Download
	replica_2		Download
	replica_3		Download
	replica_4		Download
	replica_5		Download
	replica_6		Download
	replica_7		Download
	replica_8		Download
	replica_9		Download
	replica_10		Download

Selected model: model_1.pdb (most representative model of the best cluster) download the model

Details about clusters

cluster name	cluster density	average rmsd	max rmsd	number of elements
cluster_1.pdb ( medoid)	69.2449	0.852048	1.41762	59
cluster_2.pdb ( medoid)	24.033	0.70736	1.27965	17
cluster_3.pdb ( medoid)	23.0777	2.55658	8.449	59
cluster_4.pdb ( medoid)	18.8827	1.271	2.22547	24
cluster_5.pdb ( medoid)	17.3263	3.80924	11.7899	66
cluster_6.pdb ( medoid)	15.3046	2.22155	8.34383	34
cluster_7.pdb ( medoid)	13.7525	4.21741	6.35911	58
cluster_8.pdb ( medoid)	12.9072	3.17653	7.7759	41
cluster_9.pdb ( medoid)	7.94154	5.16273	8.68122	41
cluster_10.pdb ( medoid)	3.19882	7.19015	19.7372	23