CABS-dock: raf_mek

Project name: raf_mek_monomer-11

Status: done

submitted: 2026-01-16 18:24:04, status changed: 2026-01-17 12:33:37

Project settings

Protein sequence(s)	LKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAEERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIDWEIPDGQITVGQRIGGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARRQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLP input pdb
Peptide sequence	VLRKTRHVNILLFMG
Simulation mc cycles	50
Peptide secondary structure psipred	CCCCCCEEEEEEEEC

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Zoom/rotate predicted model of the complex using mouse. Click the "View" button on the right panel to load the appropriate model. View in JSmol (pure html5/js) if you got rendering problems.

Models are ranked and numbered according to their occurrence in docking trajectory (1 = most probable result).

Representative conformations

	model_1		Download
	model_2		Download
	model_3		Download
	model_4		Download
	model_5		Download
	model_6		Download
	model_7		Download
	model_8		Download
	model_9		Download
	model_10		Download

Download all files

Click the "View" button to load the contact map of appropriate model.

Representative conformations

Contact cutoff (Å)

	model_1	View
	model_2	View
	model_3	View
	model_4	View
	model_5	View
	model_6	View
	model_7	View
	model_8	View
	model_9	View
	model_10	View

Receptor residue	Peptide residue

Receptor residue	Peptide residue

Receptor residue	Peptide residue

Select trajectory from the right panel to display animation in JSmol. Note that it may hangs browser window for few minutes or ever.

Trajectories

	replica_1		Download
	replica_2		Download
	replica_3		Download
	replica_4		Download
	replica_5		Download
	replica_6		Download
	replica_7		Download
	replica_8		Download
	replica_9		Download
	replica_10		Download

Selected model: model_1.pdb (most representative model of the best cluster) download the model

Details about clusters

cluster name	cluster density	average rmsd	max rmsd	number of elements
cluster_1.pdb ( medoid)	94.8623	1.05416	3.26264	100
cluster_2.pdb ( medoid)	22.9113	5.36853	19.3791	123
cluster_3.pdb ( medoid)	20.3393	8.65322	45.5027	176
cluster_4.pdb ( medoid)	20.2377	4.6448	31.9306	94
cluster_5.pdb ( medoid)	16.2639	4.7959	9.28059	78
cluster_6.pdb ( medoid)	14.7775	5.75198	14.167	85
cluster_7.pdb ( medoid)	12.7249	7.93719	18.6719	101
cluster_8.pdb ( medoid)	11.2161	5.17112	32.1236	58
cluster_9.pdb ( medoid)	4.89904	13.0638	27.0979	64
cluster_10.pdb ( medoid)	3.26566	18.9854	46.6963	62