CABS-dock: raf_mek

Project name: raf_mek_monomer-6

Status: done

submitted: 2026-01-16 18:21:11, status changed: 2026-01-17 12:06:19

Project settings

Protein sequence(s)	LKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAEERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIDWEIPDGQITVGQRIGGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARRQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLP input pdb
Peptide sequence	TRHVNILLFM
Simulation mc cycles	50
Peptide secondary structure psipred	CCEEEEEEEC

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Zoom/rotate predicted model of the complex using mouse. Click the "View" button on the right panel to load the appropriate model. View in JSmol (pure html5/js) if you got rendering problems.

Models are ranked and numbered according to their occurrence in docking trajectory (1 = most probable result).

Representative conformations

	model_1		Download
	model_2		Download
	model_3		Download
	model_4		Download
	model_5		Download
	model_6		Download
	model_7		Download
	model_8		Download
	model_9		Download
	model_10		Download

Download all files

Click the "View" button to load the contact map of appropriate model.

Representative conformations

Contact cutoff (Å)

	model_1	View
	model_2	View
	model_3	View
	model_4	View
	model_5	View
	model_6	View
	model_7	View
	model_8	View
	model_9	View
	model_10	View

Receptor residue	Peptide residue

Receptor residue	Peptide residue

Receptor residue	Peptide residue

Select trajectory from the right panel to display animation in JSmol. Note that it may hangs browser window for few minutes or ever.

Trajectories

	replica_1		Download
	replica_2		Download
	replica_3		Download
	replica_4		Download
	replica_5		Download
	replica_6		Download
	replica_7		Download
	replica_8		Download
	replica_9		Download
	replica_10		Download

Selected model: model_1.pdb (most representative model of the best cluster) download the model

Details about clusters

cluster name	cluster density	average rmsd	max rmsd	number of elements
cluster_1.pdb ( medoid)	42.9602	2.37429	26.5532	102
cluster_2.pdb ( medoid)	28.2658	3.75012	32.9031	106
cluster_3.pdb ( medoid)	20.0751	5.42962	32.4951	109
cluster_4.pdb ( medoid)	19.2763	5.34335	10.6488	103
cluster_5.pdb ( medoid)	18.1707	5.83357	34.3852	106
cluster_6.pdb ( medoid)	13.6817	7.89375	27.8705	108
cluster_7.pdb ( medoid)	12.6974	9.13572	21.1888	116
cluster_8.pdb ( medoid)	12.3519	5.42428	26.1381	67
cluster_9.pdb ( medoid)	4.07351	12.2744	29.1616	50
cluster_10.pdb ( medoid)	2.55741	12.9037	32.359	33