CABS-dock: EGFR

Project name: EGFR

Status: done

submitted: 2026-04-03 05:35:51, status changed: 2026-04-03 12:51:48

Project settings

Protein sequence(s)	GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGSLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAAAAEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLI input pdb
Peptide sequence	KTKAQPAVTSK
Simulation mc cycles	50
Peptide secondary structure psipred	CCCCCCCCCCC

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Zoom/rotate predicted model of the complex using mouse. Click the "View" button on the right panel to load the appropriate model. View in JSmol (pure html5/js) if you got rendering problems.

Models are ranked and numbered according to their occurrence in docking trajectory (1 = most probable result).

Representative conformations

	model_1		Download
	model_2		Download
	model_3		Download
	model_4		Download
	model_5		Download
	model_6		Download
	model_7		Download
	model_8		Download
	model_9		Download
	model_10		Download

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Click the "View" button to load the contact map of appropriate model.

Representative conformations

Contact cutoff (Å)

	model_1	View
	model_2	View
	model_3	View
	model_4	View
	model_5	View
	model_6	View
	model_7	View
	model_8	View
	model_9	View
	model_10	View

Receptor residue	Peptide residue

Receptor residue	Peptide residue

Receptor residue	Peptide residue

Select trajectory from the right panel to display animation in JSmol. Note that it may hangs browser window for few minutes or ever.

Trajectories

	replica_1		Download
	replica_2		Download
	replica_3		Download
	replica_4		Download
	replica_5		Download
	replica_6		Download
	replica_7		Download
	replica_8		Download
	replica_9		Download
	replica_10		Download

Selected model: model_1.pdb (most representative model of the best cluster) download the model

Details about clusters

cluster name	cluster density	average rmsd	max rmsd	number of elements
cluster_1.pdb ( medoid)	31.7579	3.36924	17.6331	107
cluster_2.pdb ( medoid)	24.6349	6.37309	37.3503	157
cluster_3.pdb ( medoid)	19.4894	5.28493	22.3687	103
cluster_4.pdb ( medoid)	19.1791	6.51751	21.6925	125
cluster_5.pdb ( medoid)	18.2403	6.14024	12.9849	112
cluster_6.pdb ( medoid)	14.4981	9.79439	33.6062	142
cluster_7.pdb ( medoid)	11.0394	6.52212	18.5045	72
cluster_8.pdb ( medoid)	7.78581	10.6604	31.7792	83
cluster_9.pdb ( medoid)	6.94592	6.04672	18.9285	42
cluster_10.pdb ( medoid)	4.78005	11.9245	29.124	57