Project name: C4mod

Chain sequence(s)	H: QVQLVQSGAEVKKPGASVKVSCKASGSTFGSYAISWVRQAPGQGLEWMGVIIPLDGKTTYAEKFQGRVTITADTSTNTVYMEMSSLRSEDTAMYYCARHRRHYSGTLGYLKFWGQGALVTVSS; L: EIELTQSPATLSLSPGETATLSCRASQSVGINLAWYQQKPGQPPKLLVHSAIFRAAGIPDRFSGRGSGTEFTLTITSLEPEDVGLYYCQQYHDWNSFGQGTKVEIKR
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2141
• Maximal score value: 1.9685
• Average score: -0.6737
• Total score value: -154.9605

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	L	-3.2141
2	I	L	0.0000
3	E	L	-2.9943
4	L	L	0.0000
5	T	L	-1.6690
6	Q	L	0.0000
7	S	L	-0.8572
8	P	L	-0.4017
9	A	L	-0.5277
10	T	L	-0.6259
11	L	L	-0.5224
12	S	L	-1.1467
13	L	L	-1.1221
14	S	L	-1.5400
15	P	L	-1.5276
16	G	L	-1.3748
17	E	L	-1.4137
18	T	L	-0.8440
19	A	L	0.0000
20	T	L	-0.2315
21	L	L	0.0000
22	S	L	-1.2134
23	C	L	0.0000
24	R	L	-3.0824
25	A	L	0.0000
26	S	L	-2.2190
27	Q	L	-2.6234
28	S	L	-1.7982
29	V	L	0.0000
30	G	L	-0.3048
31	I	L	0.3338
32	N	L	-0.0961
33	L	L	0.0000
34	A	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	0.0000
39	K	L	-1.3239
40	P	L	-1.0886
41	G	L	-1.3562
42	Q	L	-1.8725
43	P	L	-1.2404
44	P	L	0.0000
45	K	L	-1.1302
46	L	L	0.0000
47	L	L	0.0000
48	V	L	0.0000
49	H	L	0.8719
50	S	L	0.0000
51	A	L	0.0000
52	I	L	1.7433
53	F	L	1.9685
54	R	L	-0.0203
55	A	L	-0.0071
56	A	L	-0.1599
57	G	L	-0.7176
58	I	L	-0.8163
59	P	L	-1.1906
60	D	L	-2.1480
61	R	L	-1.4178
62	F	L	0.0000
63	S	L	-0.4806
64	G	L	0.0000
65	R	L	-1.3219
66	G	L	-1.2912
67	S	L	-0.8473
68	G	L	-1.1549
69	T	L	-1.9199
70	E	L	-2.9786
71	F	L	0.0000
72	T	L	-1.1982
73	L	L	0.0000
74	T	L	-0.4643
75	I	L	0.0000
76	T	L	-0.8862
77	S	L	-1.0363
78	L	L	0.0000
79	E	L	-2.0952
80	P	L	-1.6978
81	E	L	-2.2282
82	D	L	0.0000
83	V	L	-0.7634
84	G	L	0.0000
85	L	L	-0.5107
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	Q	L	0.0000
90	Q	L	0.0000
91	Y	L	0.0000
92	H	L	-1.9435
93	D	L	-2.7143
94	W	L	-1.4842
95	N	L	-1.1585
97	S	L	-1.2148
98	F	L	-0.5930
99	G	L	0.0000
100	Q	L	-1.6431
101	G	L	0.0000
102	T	L	0.0000
103	K	L	-1.2648
104	V	L	0.0000
105	E	L	-1.5110
106	I	L	-1.2924
107	K	L	-2.6207
108	R	L	-2.6770
1	Q	H	-1.4709
2	V	H	-1.0480
3	Q	H	-1.4726
4	L	H	0.0000
5	V	H	0.0373
6	Q	H	0.0000
7	S	H	-0.4526
8	G	H	-0.4118
9	A	H	0.3547
10	E	H	0.2705
11	V	H	1.0670
12	K	H	-0.9300
13	K	H	-2.1374
14	P	H	-2.1311
15	G	H	-1.4563
16	A	H	-1.1459
17	S	H	-1.2581
18	V	H	0.0000
19	K	H	-1.7719
20	V	H	0.0000
21	S	H	-0.5315
22	C	H	0.0000
23	K	H	-1.0953
24	A	H	0.0000
25	S	H	-1.0258
26	G	H	-1.0313
27	S	H	-0.7707
28	T	H	-0.4487
29	F	H	0.0000
30	G	H	-0.5776
31	S	H	0.0000
32	Y	H	0.0000
33	A	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.3210
39	Q	H	0.0000
40	A	H	-0.8958
41	P	H	-0.7571
42	G	H	-1.2328
43	Q	H	-1.8375
44	G	H	-1.2956
45	L	H	0.0000
46	E	H	-0.7327
47	W	H	0.0000
48	M	H	0.0000
49	G	H	0.0000
50	V	H	0.0000
51	I	H	0.0000
52	I	H	-0.8034
52A	P	H	-0.7832
53	L	H	-0.4469
54	D	H	-1.3480
55	G	H	-1.4748
56	K	H	-2.0070
57	T	H	-0.9917
58	T	H	-0.5698
59	Y	H	-0.8556
60	A	H	0.0000
61	E	H	-3.1162
62	K	H	-2.9432
63	F	H	0.0000
64	Q	H	-2.2740
65	G	H	-1.6646
66	R	H	-1.3510
67	V	H	0.0000
68	T	H	-0.7893
69	I	H	0.0000
70	T	H	-0.4976
71	A	H	-0.5428
72	D	H	-1.1508
73	T	H	-0.7235
74	S	H	-0.6548
75	T	H	-0.7826
76	N	H	-1.0950
77	T	H	0.0000
78	V	H	0.0000
79	Y	H	-0.5831
80	M	H	0.0000
81	E	H	-1.4813
82	M	H	0.0000
82A	S	H	-1.0800
82B	S	H	-1.0928
82C	L	H	0.0000
83	R	H	-2.7723
84	S	H	-2.2732
85	E	H	-2.4432
86	D	H	0.0000
87	T	H	-0.6941
88	A	H	0.0000
89	M	H	0.3102
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0000
95	H	H	0.0000
96	R	H	-0.8085
97	R	H	-1.1077
98	H	H	-0.5164
99	Y	H	0.5604
100	S	H	-0.1824
100A	G	H	-0.6708
100B	T	H	-0.5459
100C	L	H	-0.3026
100D	G	H	0.0000
100E	Y	H	0.0543
100F	L	H	0.0000
101	K	H	-0.4034
102	F	H	-0.4414
103	W	H	-0.4229
104	G	H	0.0000
105	Q	H	-1.2341
106	G	H	0.0000
107	A	H	0.0000
108	L	H	0.8820
109	V	H	0.0000
110	T	H	-0.0903
111	V	H	0.0000
112	S	H	-1.2959
113	S	H	-1.0349