Project name: 1a0396013b33857
Status: done
submitted: 2018-01-12 16:01:51, status changed: 2018-01-12 16:09:02
Settings
Chain sequence(s)
|
A: KGEELFTGVVPILVELDGDVNGHKFSVSSSGEGEGDATYGKLTTLKFIICTTGKLPVPWPTLVTTLVQCFSRYPDHMKKQHDFFKSAMPEGYVQERTIFFKKDDGNYKKTRAEVKFEGDDTLVNRIEELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIKVNNFKIRHNIEEDGSVQLADHYQQQNTTPIGDDGPVLLPDDNHYLSTQSALSKDPNEKRDHMVLLEEFVTAAGIT
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.9638
-
Maximal score value
-
1.3222
-
Average score
-
-0.9391
-
Total score value
-
-211.2993
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
3 |
K |
A |
-2.6665 |
|
4 |
G |
A |
0.0000 |
|
5 |
E |
A |
-3.0833 |
|
6 |
E |
A |
-2.9198 |
|
7 |
L |
A |
-1.2572 |
|
8 |
F |
A |
0.0000 |
|
9 |
T |
A |
-0.4733 |
|
10 |
G |
A |
0.4727 |
|
11 |
V |
A |
1.3222 |
|
12 |
V |
A |
0.0000 |
|
13 |
P |
A |
-0.8590 |
|
14 |
I |
A |
0.0000 |
|
15 |
L |
A |
-1.0557 |
|
16 |
V |
A |
0.0000 |
|
17 |
E |
A |
-2.1111 |
|
18 |
L |
A |
0.0000 |
|
19 |
D |
A |
-3.4790 |
|
20 |
G |
A |
0.0000 |
|
21 |
D |
A |
-2.8487 |
|
22 |
V |
A |
0.0000 |
|
23 |
N |
A |
-2.1761 |
|
24 |
G |
A |
-1.7547 |
|
25 |
H |
A |
-2.1436 |
|
26 |
K |
A |
-2.9915 |
|
27 |
F |
A |
0.0000 |
|
28 |
S |
A |
-1.8171 |
|
29 |
V |
A |
0.0000 |
|
30 |
S |
A |
-1.0589 |
|
31 |
G |
A |
0.0000 |
|
32 |
E |
A |
-2.0841 |
|
33 |
G |
A |
-1.3901 |
|
34 |
E |
A |
-1.3778 |
|
35 |
G |
A |
0.0000 |
|
36 |
D |
A |
0.1035 |
|
37 |
A |
A |
0.0000 |
|
38 |
T |
A |
0.1985 |
|
39 |
Y |
A |
0.9029 |
|
40 |
G |
A |
0.0000 |
|
41 |
K |
A |
-0.3429 |
|
42 |
L |
A |
0.0000 |
|
43 |
T |
A |
-0.6234 |
|
44 |
L |
A |
0.0000 |
|
45 |
K |
A |
-0.9096 |
|
46 |
F |
A |
0.0000 |
|
47 |
I |
A |
-1.0942 |
|
48 |
C |
A |
0.0000 |
|
49 |
T |
A |
-0.9711 |
|
50 |
T |
A |
-1.3459 |
|
51 |
G |
A |
-1.6871 |
|
52 |
K |
A |
-2.2885 |
|
53 |
L |
A |
0.0000 |
|
54 |
P |
A |
-1.2241 |
|
55 |
V |
A |
0.0000 |
|
56 |
P |
A |
0.0000 |
|
57 |
W |
A |
0.0000 |
|
58 |
P |
A |
0.0000 |
|
59 |
T |
A |
0.0000 |
|
60 |
L |
A |
0.0000 |
|
61 |
V |
A |
0.0000 |
|
62 |
T |
A |
-0.0038 |
|
63 |
T |
A |
0.0000 |
|
64 |
L |
A |
0.0000 |
|
68 |
V |
A |
-0.0317 |
|
69 |
Q |
A |
-0.2291 |
|
70 |
C |
A |
0.0000 |
|
71 |
F |
A |
0.0000 |
|
72 |
S |
A |
0.0000 |
|
73 |
R |
A |
-1.3671 |
|
74 |
Y |
A |
-1.5292 |
|
75 |
P |
A |
-1.9179 |
|
76 |
D |
A |
-2.9712 |
|
77 |
H |
A |
-2.3552 |
|
78 |
M |
A |
0.0000 |
|
79 |
K |
A |
-2.9588 |
|
80 |
Q |
A |
-2.2496 |
|
81 |
H |
A |
-1.4757 |
|
82 |
D |
A |
0.0000 |
|
83 |
F |
A |
0.0000 |
|
84 |
F |
A |
0.0000 |
|
85 |
K |
A |
0.0000 |
|
86 |
S |
A |
-1.3274 |
|
87 |
A |
A |
0.0000 |
|
88 |
M |
A |
0.0000 |
|
89 |
P |
A |
-1.7557 |
|
90 |
E |
A |
-2.3131 |
|
91 |
G |
A |
0.0000 |
|
92 |
Y |
A |
0.0000 |
|
93 |
V |
A |
-0.7093 |
|
94 |
Q |
A |
0.0000 |
|
95 |
E |
A |
-1.8953 |
|
96 |
R |
A |
0.0000 |
|
97 |
T |
A |
-0.3453 |
|
98 |
I |
A |
0.0000 |
|
99 |
F |
A |
0.3086 |
|
100 |
F |
A |
0.0000 |
|
101 |
K |
A |
-1.7701 |
|
102 |
D |
A |
-2.8299 |
|
103 |
D |
A |
-2.4300 |
|
104 |
G |
A |
0.0000 |
|
105 |
N |
A |
-0.7928 |
|
106 |
Y |
A |
0.0000 |
|
107 |
K |
A |
-1.8276 |
|
108 |
T |
A |
0.0000 |
|
109 |
R |
A |
-2.8293 |
|
110 |
A |
A |
0.0000 |
|
111 |
E |
A |
-2.0624 |
|
112 |
V |
A |
0.0000 |
|
113 |
K |
A |
-1.5900 |
|
114 |
F |
A |
-1.7632 |
|
115 |
E |
A |
-2.5288 |
|
116 |
G |
A |
-2.1435 |
|
117 |
D |
A |
-2.3592 |
|
118 |
T |
A |
-1.6406 |
|
119 |
L |
A |
0.0000 |
|
120 |
V |
A |
0.0000 |
|
121 |
N |
A |
0.0000 |
|
122 |
R |
A |
-3.0940 |
|
123 |
I |
A |
0.0000 |
|
124 |
E |
A |
-3.9638 |
|
125 |
L |
A |
0.0000 |
|
126 |
K |
A |
-2.7844 |
|
127 |
G |
A |
0.0000 |
|
128 |
I |
A |
-1.2289 |
|
129 |
D |
A |
-2.5095 |
|
130 |
F |
A |
0.0000 |
|
131 |
K |
A |
-3.9138 |
|
132 |
E |
A |
-3.9229 |
|
133 |
D |
A |
-3.4739 |
|
134 |
G |
A |
-2.7208 |
|
135 |
N |
A |
-2.0541 |
|
136 |
I |
A |
0.0000 |
|
137 |
L |
A |
-1.8552 |
|
138 |
G |
A |
-2.0802 |
|
139 |
H |
A |
-1.7612 |
|
140 |
K |
A |
-2.1690 |
|
141 |
L |
A |
-1.4749 |
|
142 |
E |
A |
-1.5583 |
|
143 |
Y |
A |
-0.5321 |
|
144 |
N |
A |
-0.5626 |
|
145 |
Y |
A |
-0.8649 |
|
146 |
N |
A |
-1.2728 |
|
147 |
S |
A |
-1.2733 |
|
148 |
H |
A |
0.0000 |
|
149 |
N |
A |
-1.2184 |
|
150 |
V |
A |
0.0000 |
|
151 |
Y |
A |
0.5686 |
|
152 |
I |
A |
0.0000 |
|
153 |
M |
A |
-0.7683 |
|
154 |
A |
A |
-1.4695 |
|
155 |
D |
A |
0.0000 |
|
156 |
K |
A |
-2.9231 |
|
157 |
Q |
A |
-2.8592 |
|
158 |
K |
A |
-2.8612 |
|
159 |
N |
A |
-2.4527 |
|
160 |
G |
A |
0.0000 |
|
161 |
I |
A |
0.0000 |
|
162 |
K |
A |
-1.0508 |
|
163 |
V |
A |
0.0000 |
|
164 |
N |
A |
-0.2574 |
|
165 |
F |
A |
0.0000 |
|
166 |
K |
A |
-1.8295 |
|
167 |
I |
A |
0.0000 |
|
168 |
R |
A |
-1.6157 |
|
169 |
H |
A |
0.0000 |
|
170 |
N |
A |
-1.4518 |
|
171 |
I |
A |
0.0000 |
|
172 |
E |
A |
-3.1816 |
|
173 |
D |
A |
-3.0044 |
|
174 |
G |
A |
-1.8971 |
|
175 |
S |
A |
-1.0102 |
|
176 |
V |
A |
-0.3097 |
|
177 |
Q |
A |
0.0000 |
|
178 |
L |
A |
-0.9723 |
|
179 |
A |
A |
0.0000 |
|
180 |
D |
A |
0.0000 |
|
181 |
H |
A |
0.0000 |
|
182 |
Y |
A |
0.5970 |
|
183 |
Q |
A |
0.0000 |
|
184 |
Q |
A |
-0.8700 |
|
185 |
N |
A |
0.0000 |
|
186 |
T |
A |
-0.9361 |
|
187 |
P |
A |
-0.8127 |
|
188 |
I |
A |
-0.3629 |
|
189 |
G |
A |
-1.3412 |
|
190 |
D |
A |
-2.1863 |
|
191 |
G |
A |
-1.5057 |
|
192 |
P |
A |
-0.6748 |
|
193 |
V |
A |
-0.1818 |
|
194 |
L |
A |
-0.0246 |
|
195 |
L |
A |
-0.4505 |
|
196 |
P |
A |
0.0000 |
|
197 |
D |
A |
-2.3053 |
|
198 |
N |
A |
-1.7626 |
|
199 |
H |
A |
0.0000 |
|
200 |
Y |
A |
0.0105 |
|
201 |
L |
A |
0.0000 |
|
202 |
S |
A |
-0.6262 |
|
203 |
T |
A |
-0.8678 |
|
204 |
Q |
A |
-1.3369 |
|
205 |
S |
A |
-0.5504 |
|
206 |
A |
A |
-0.0005 |
|
207 |
L |
A |
-0.0012 |
|
208 |
S |
A |
-0.6819 |
|
209 |
K |
A |
-1.9468 |
|
210 |
D |
A |
-2.1374 |
|
211 |
P |
A |
-1.8420 |
|
212 |
N |
A |
-2.4801 |
|
213 |
E |
A |
-2.7202 |
|
214 |
K |
A |
-3.3060 |
|
215 |
R |
A |
-3.3854 |
|
216 |
D |
A |
-2.2790 |
|
217 |
H |
A |
0.0000 |
|
218 |
M |
A |
0.0000 |
|
219 |
V |
A |
-0.2619 |
|
220 |
L |
A |
0.0000 |
|
221 |
L |
A |
0.4483 |
|
222 |
E |
A |
-0.1320 |
|
223 |
F |
A |
0.0302 |
|
224 |
V |
A |
0.0000 |
|
225 |
T |
A |
-0.5034 |
|
226 |
A |
A |
0.0000 |
|
227 |
A |
A |
-0.4048 |
|
228 |
G |
A |
-0.4767 |
|
229 |
I |
A |
-0.4828 |
|
230 |
T |
A |
-0.1838 |
|