Project name: 4ojf:L
Status: done
submitted: 2019-03-21 14:48:27, status changed: 2019-03-21 14:58:42
Settings
Chain sequence(s)
|
L: YVVMTQSPLSLPVTPGEPASISCKSSQSLLDSDGKTYLNWLLQKPGQSPQRLIYLVSKLDSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCWQGTHFPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.0054
-
Maximal score value
-
1.7103
-
Average score
-
-0.8836
-
Total score value
-
-193.498
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
Y |
L |
1.7103 |
|
2 |
V |
L |
0.0000 |
|
3 |
V |
L |
1.6447 |
|
4 |
M |
L |
0.0000 |
|
5 |
T |
L |
-0.2138 |
|
6 |
Q |
L |
0.0000 |
|
7 |
S |
L |
-0.2259 |
|
8 |
P |
L |
0.0806 |
|
9 |
L |
L |
0.4323 |
|
10 |
S |
L |
-0.2905 |
|
11 |
L |
L |
-0.4652 |
|
12 |
P |
L |
-0.9725 |
|
13 |
V |
L |
0.0000 |
|
14 |
T |
L |
-1.8486 |
|
15 |
P |
L |
-2.0935 |
|
16 |
G |
L |
-2.2134 |
|
17 |
E |
L |
-2.9982 |
|
18 |
P |
L |
-2.5546 |
|
19 |
A |
L |
0.0000 |
|
20 |
S |
L |
-0.9370 |
|
21 |
I |
L |
0.0000 |
|
22 |
S |
L |
-0.8630 |
|
23 |
C |
L |
0.0000 |
|
24 |
K |
L |
-1.7245 |
|
25 |
S |
L |
0.0000 |
|
26 |
S |
L |
-0.0972 |
|
27 |
Q |
L |
-0.2832 |
|
27A |
S |
L |
-0.3546 |
|
27B |
L |
L |
0.0000 |
|
27C |
L |
L |
0.3881 |
|
27D |
D |
L |
-0.9762 |
|
27E |
S |
L |
-1.2953 |
|
28 |
D |
L |
-2.3341 |
|
29 |
G |
L |
-1.6335 |
|
30 |
K |
L |
-1.3993 |
|
31 |
T |
L |
-0.3179 |
|
32 |
Y |
L |
0.1348 |
|
33 |
L |
L |
0.0000 |
|
34 |
N |
L |
-0.1287 |
|
35 |
W |
L |
0.0000 |
|
36 |
L |
L |
0.0000 |
|
37 |
L |
L |
0.0000 |
|
38 |
Q |
L |
-1.4898 |
|
39 |
K |
L |
-1.8514 |
|
40 |
P |
L |
-1.6990 |
|
41 |
G |
L |
-1.6281 |
|
42 |
Q |
L |
-1.8721 |
|
43 |
S |
L |
-1.3414 |
|
44 |
P |
L |
-1.5617 |
|
45 |
Q |
L |
-2.1168 |
|
46 |
R |
L |
-2.0922 |
|
47 |
L |
L |
0.0000 |
|
48 |
I |
L |
0.0000 |
|
49 |
Y |
L |
-0.1871 |
|
50 |
L |
L |
-0.0271 |
|
51 |
V |
L |
0.0000 |
|
52 |
S |
L |
-0.6393 |
|
53 |
K |
L |
-0.9508 |
|
54 |
L |
L |
-0.8781 |
|
55 |
D |
L |
-1.2303 |
|
56 |
S |
L |
-0.8233 |
|
57 |
G |
L |
-0.7486 |
|
58 |
V |
L |
-0.9442 |
|
59 |
P |
L |
-1.1385 |
|
60 |
D |
L |
-2.0472 |
|
61 |
R |
L |
-2.2811 |
|
62 |
F |
L |
0.0000 |
|
63 |
S |
L |
-1.5169 |
|
64 |
G |
L |
-0.8805 |
|
65 |
S |
L |
-1.0191 |
|
66 |
G |
L |
-1.0165 |
|
67 |
S |
L |
-0.6277 |
|
68 |
G |
L |
-0.4674 |
|
69 |
T |
L |
-1.1183 |
|
70 |
D |
L |
-1.9824 |
|
71 |
F |
L |
0.0000 |
|
72 |
T |
L |
-1.1747 |
|
73 |
L |
L |
0.0000 |
|
74 |
K |
L |
-2.2694 |
|
75 |
I |
L |
0.0000 |
|
76 |
S |
L |
-2.6599 |
|
77 |
R |
L |
-3.4496 |
|
78 |
V |
L |
0.0000 |
|
79 |
E |
L |
-2.9518 |
|
80 |
A |
L |
-2.5843 |
|
81 |
E |
L |
-2.9588 |
|
82 |
D |
L |
0.0000 |
|
83 |
V |
L |
0.0000 |
|
84 |
G |
L |
0.0000 |
|
85 |
V |
L |
-0.6971 |
|
86 |
Y |
L |
0.0000 |
|
87 |
Y |
L |
-0.2404 |
|
88 |
C |
L |
0.0000 |
|
89 |
W |
L |
0.2187 |
|
90 |
Q |
L |
0.0000 |
|
91 |
G |
L |
-0.3511 |
|
92 |
T |
L |
-0.3917 |
|
93 |
H |
L |
0.2816 |
|
94 |
F |
L |
1.2286 |
|
95 |
P |
L |
0.2212 |
|
96 |
R |
L |
-0.9054 |
|
97 |
T |
L |
0.2408 |
|
98 |
F |
L |
0.6284 |
|
99 |
G |
L |
0.0000 |
|
100 |
Q |
L |
-0.6623 |
|
101 |
G |
L |
0.0000 |
|
102 |
T |
L |
0.0000 |
|
103 |
K |
L |
-1.6123 |
|
104 |
V |
L |
0.0000 |
|
105 |
E |
L |
-1.4786 |
|
106 |
I |
L |
0.0000 |
|
107 |
K |
L |
-1.5331 |
|
108 |
R |
L |
-1.0395 |
|
109 |
T |
L |
-0.1590 |
|
110 |
V |
L |
0.1620 |
|
111 |
A |
L |
-0.1799 |
|
112 |
A |
L |
-0.2432 |
|
113 |
P |
L |
0.0000 |
|
114 |
S |
L |
-0.1205 |
|
115 |
V |
L |
0.0000 |
|
116 |
F |
L |
1.2686 |
|
117 |
I |
L |
1.2779 |
|
118 |
F |
L |
1.5055 |
|
119 |
P |
L |
-0.0663 |
|
120 |
P |
L |
-0.5265 |
|
121 |
S |
L |
-1.5940 |
|
122 |
D |
L |
-3.0551 |
|
123 |
E |
L |
-3.3134 |
|
124 |
Q |
L |
-2.3381 |
|
125 |
L |
L |
-2.2703 |
|
126 |
K |
L |
-2.9826 |
|
127 |
S |
L |
-2.0215 |
|
128 |
G |
L |
-1.5725 |
|
129 |
T |
L |
-1.3391 |
|
130 |
A |
L |
0.0000 |
|
131 |
S |
L |
0.0477 |
|
132 |
V |
L |
0.0000 |
|
133 |
V |
L |
0.7180 |
|
134 |
C |
L |
0.0000 |
|
135 |
L |
L |
0.6495 |
|
136 |
L |
L |
0.0000 |
|
137 |
N |
L |
-0.5989 |
|
138 |
N |
L |
-1.2509 |
|
139 |
F |
L |
0.0000 |
|
140 |
Y |
L |
0.0000 |
|
141 |
P |
L |
-1.7535 |
|
142 |
R |
L |
-2.9235 |
|
143 |
E |
L |
-3.0725 |
|
144 |
A |
L |
-2.0925 |
|
145 |
K |
L |
-1.8933 |
|
146 |
V |
L |
-0.7773 |
|
147 |
Q |
L |
-0.5091 |
|
148 |
W |
L |
0.0000 |
|
149 |
K |
L |
-0.5771 |
|
150 |
V |
L |
0.0000 |
|
151 |
D |
L |
-1.6080 |
|
152 |
N |
L |
-1.2253 |
|
153 |
A |
L |
-0.2424 |
|
154 |
L |
L |
0.6019 |
|
155 |
Q |
L |
-0.4375 |
|
156 |
S |
L |
-0.8914 |
|
157 |
G |
L |
-1.4591 |
|
158 |
N |
L |
-1.9066 |
|
159 |
S |
L |
-1.9159 |
|
160 |
Q |
L |
-2.5177 |
|
161 |
E |
L |
-2.3344 |
|
162 |
S |
L |
-1.3781 |
|
163 |
V |
L |
-0.7999 |
|
164 |
T |
L |
-1.3182 |
|
165 |
E |
L |
-2.3613 |
|
166 |
Q |
L |
0.0000 |
|
167 |
D |
L |
-2.5430 |
|
168 |
S |
L |
-2.6502 |
|
169 |
K |
L |
-2.9119 |
|
170 |
D |
L |
-2.0521 |
|
171 |
S |
L |
0.0000 |
|
172 |
T |
L |
0.0000 |
|
173 |
Y |
L |
0.0000 |
|
174 |
S |
L |
-0.9961 |
|
175 |
L |
L |
0.0000 |
|
176 |
S |
L |
-0.4827 |
|
177 |
S |
L |
0.0000 |
|
178 |
T |
L |
-0.7995 |
|
179 |
L |
L |
0.0000 |
|
180 |
T |
L |
-0.6667 |
|
181 |
L |
L |
-0.9911 |
|
182 |
S |
L |
-1.6177 |
|
183 |
K |
L |
-2.7119 |
|
184 |
A |
L |
-2.2840 |
|
185 |
D |
L |
-2.7845 |
|
186 |
Y |
L |
0.0000 |
|
187 |
E |
L |
-4.0054 |
|
188 |
K |
L |
-3.6934 |
|
189 |
H |
L |
-3.2037 |
|
190 |
K |
L |
-3.3793 |
|
191 |
V |
L |
-1.8912 |
|
192 |
Y |
L |
0.0000 |
|
193 |
A |
L |
-0.8650 |
|
194 |
C |
L |
0.0000 |
|
195 |
E |
L |
-0.5596 |
|
196 |
V |
L |
0.0000 |
|
197 |
T |
L |
-0.9986 |
|
198 |
H |
L |
0.0000 |
|
199 |
Q |
L |
-1.6990 |
|
200 |
G |
L |
-0.4607 |
|
201 |
L |
L |
-0.1774 |
|
202 |
S |
L |
-0.4078 |
|
203 |
S |
L |
-0.4026 |
|
204 |
P |
L |
-0.4198 |
|
205 |
V |
L |
0.0054 |
|
206 |
T |
L |
-0.3819 |
|
207 |
K |
L |
-0.4669 |
|
208 |
S |
L |
-0.4791 |
|
209 |
F |
L |
-1.2199 |
|
210 |
N |
L |
-2.7938 |
|
211 |
R |
L |
-3.3494 |
|
212 |
G |
L |
-2.3367 |
|
213 |
E |
L |
-2.4455 |
|
214 |
C |
L |
-0.8325 |
|