Project name: 2x04_modified_chains-AC.pdb_stat_DIBS

Chain sequence(s)	A: GPLGSLTASSMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESSLRSSKVDEAVAVLQA; C: WPPEFHPGVPWKGLQ
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3317
• Maximal score value: 1.0116
• Average score: -0.8111
• Total score value: -74.6238

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
540	G	A	-0.2768
541	P	A	0.1021
542	L	A	0.9797
543	G	A	0.0778
544	S	A	-0.0241
545	L	A	0.0415
546	T	A	0.0271
547	A	A	-0.0752
548	S	A	-0.0047
549	M	A	0.2857
550	L	A	0.0000
551	A	A	-0.2397
552	S	A	-0.3061
553	A	A	-0.6360
554	P	A	-1.1181
555	P	A	-1.2524
556	Q	A	-1.9904
557	E	A	-1.8900
558	Q	A	-1.0671
559	K	A	-1.4878
560	Q	A	-1.3092
561	M	A	-0.3945
562	L	A	0.0000
563	G	A	0.0000
564	E	A	-0.2936
565	R	A	0.0182
566	L	A	0.0000
567	F	A	0.0000
568	P	A	-0.1682
569	L	A	0.2628
570	I	A	0.0000
571	Q	A	-0.6113
572	A	A	-0.1295
573	M	A	-0.4776
574	H	A	-0.4505
575	P	A	-0.5536
576	T	A	-0.4271
577	L	A	-0.5062
578	A	A	0.0000
579	G	A	-1.6309
580	K	A	-1.4229
581	I	A	0.0000
582	T	A	0.0000
583	G	A	0.0000
584	M	A	-0.8067
585	L	A	0.0000
586	L	A	0.0000
587	E	A	-1.9920
588	I	A	-1.6755
589	D	A	-2.5550
590	N	A	-1.9085
591	S	A	-1.5564
592	E	A	-2.3466
593	L	A	0.0000
594	L	A	0.0000
595	H	A	-1.9468
596	M	A	0.0000
597	L	A	-1.2559
598	E	A	-2.4026
599	S	A	-2.0323
600	P	A	-2.0913
601	E	A	-2.8897
602	S	A	-2.2732
603	L	A	0.0000
604	R	A	-3.3317
605	S	A	-2.7563
606	K	A	-2.3743
607	V	A	0.0000
608	D	A	-2.9127
609	E	A	-2.6334
610	A	A	0.0000
611	V	A	-0.7491
612	A	A	-0.3992
613	V	A	1.0116
614	L	A	0.2577
615	Q	A	-0.5179
616	A	A	0.2156
1385	W	C	0.4913
1386	P	C	-0.5176
1387	P	C	-1.4355
1388	E	C	-2.5140
1389	F	C	0.0000
1390	H	C	-1.7741
1391	P	C	-0.7809
1392	G	C	-0.5331
1393	V	C	-0.2204
1394	P	C	-1.0930
1395	W	C	0.0000
1396	K	C	-2.3369
1397	G	C	-1.6462
1398	L	C	-1.4255
1399	Q	C	-1.9671