Project name: arg_15%_6fxn

Chain sequence(s)	A: SELTQDPAVSVALGQTVRVTCQGDSLRSYYASWYQQKPGQAPVLVIYGKNNRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCSSRDSSGNHWVFGGGTELTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTVQLQQSGAEVKKPGSSVRVSCKASGGTFNNNAINWVRQAPGQGLEWMGGIIPMFGTAKYSQNFQGRVAITADESTGTASMELSSLRSEDTAVYYCARSRDLLLFPHHALSPWGRGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.473
• Maximal score value: 2.4005
• Average score: -0.7358
• Total score value: -317.1348

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	S	A	-1.6826
3	E	A	-2.4598
4	L	A	0.0000
5	T	A	-1.4581
6	Q	A	-1.3117
7	D	A	-1.9428
8	P	A	-1.5209
9	A	A	-1.1495
10	V	A	-0.6841
11	S	A	-0.2928
12	V	A	0.0000
13	A	A	0.0007
14	L	A	-0.1366
15	G	A	-0.7558
16	Q	A	-1.1920
17	T	A	-1.0949
18	V	A	-1.0706
19	R	A	-1.7763
20	V	A	0.0000
21	T	A	-1.0365
22	C	A	0.0000
23	Q	A	-2.2473
24	G	A	-2.7592
25	D	A	-3.4730
26	S	A	0.0000
27	L	A	0.0000
28	R	A	-3.0798
29	S	A	-1.5083
30	Y	A	-0.7570
31	Y	A	-0.2510
32	A	A	0.0000
33	S	A	0.0000
34	W	A	0.0000
35	Y	A	0.0000
36	Q	A	-0.3779
37	Q	A	0.0000
38	K	A	-1.4954
39	P	A	-1.4614
40	G	A	-1.3748
41	Q	A	-1.8243
42	A	A	-0.9449
43	P	A	0.0000
44	V	A	1.2072
45	L	A	0.0000
46	V	A	0.0000
47	I	A	0.0000
48	Y	A	-1.1565
49	G	A	0.0000
50	K	A	-2.5719
51	N	A	-2.4568
52	N	A	-2.3306
53	R	A	-2.0585
54	P	A	-0.7658
55	S	A	-0.7013
56	G	A	-0.8544
57	I	A	-0.7630
58	P	A	-1.3216
59	D	A	-2.1916
60	R	A	-1.3450
61	F	A	0.0000
62	S	A	-1.5936
63	G	A	-1.4281
64	S	A	-0.9067
65	S	A	-1.2549
66	S	A	-1.2836
67	G	A	-2.1636
68	N	A	-2.9034
69	T	A	-1.7901
70	A	A	0.0000
71	S	A	0.0000
72	L	A	0.0000
73	T	A	-0.9148
74	I	A	0.0000
75	T	A	-1.1761
76	G	A	-0.8522
77	A	A	0.0000
78	Q	A	-1.2034
79	A	A	0.0000
80	E	A	-2.1739
81	D	A	0.0000
82	E	A	-2.1170
83	A	A	-1.7699
84	D	A	-1.6989
85	Y	A	0.0000
86	Y	A	0.0000
87	C	A	0.0000
88	S	A	-0.2052
89	S	A	0.0000
90	R	A	-0.8226
91	D	A	-1.5397
92	S	A	-1.6584
93	S	A	-0.9270
94	G	A	-0.9480
95	N	A	-1.6661
96	H	A	-1.1550
97	W	A	0.0000
98	V	A	-0.4698
99	F	A	-0.3538
100	G	A	0.0000
101	G	A	-1.3110
102	G	A	0.0000
103	T	A	0.0000
104	E	A	-2.2287
105	L	A	0.0000
106	T	A	-0.6138
107	V	A	0.0000
108	L	A	0.5637
109	G	A	-0.1039
110	Q	A	0.0000
111	P	A	-0.9663
112	K	A	-2.2128
113	A	A	-1.3649
114	A	A	-0.8251
115	P	A	-0.4528
116	S	A	-0.4788
117	V	A	-0.4246
118	T	A	-0.2424
119	L	A	-0.2533
120	F	A	0.0000
121	P	A	-0.0092
122	P	A	-0.6450
123	S	A	-1.1744
124	S	A	-1.5017
125	E	A	-2.5575
126	E	A	0.0000
127	L	A	-2.1415
128	Q	A	-2.4597
129	A	A	-1.9903
130	N	A	-2.7074
131	K	A	-2.5206
132	A	A	0.0000
133	T	A	0.0000
134	L	A	0.0000
135	V	A	0.0000
136	C	A	0.0000
137	L	A	0.0000
138	I	A	0.0000
139	S	A	-0.6062
140	D	A	-1.3591
141	F	A	0.0000
142	Y	A	-1.2500
143	P	A	-1.0958
144	G	A	-0.9815
145	A	A	-0.3193
146	V	A	-0.1419
147	T	A	-0.1044
148	V	A	0.3115
149	A	A	-0.3746
150	W	A	0.0000
151	K	A	-0.9660
152	A	A	0.0000
153	D	A	-1.5724
154	S	A	-0.9291
155	S	A	-0.8327
156	P	A	-0.9172
157	V	A	-0.6167
158	K	A	-1.6063
159	A	A	-0.4572
160	G	A	0.0938
161	V	A	0.6182
162	E	A	0.4655
163	T	A	0.3770
164	T	A	0.1385
165	T	A	-0.1211
166	P	A	-0.2913
167	S	A	-0.5655
168	K	A	-1.1268
169	Q	A	-1.0792
170	S	A	-1.1677
171	N	A	-1.5892
172	N	A	-1.7421
173	K	A	-1.8121
174	Y	A	-0.8956
175	A	A	0.0000
176	A	A	0.0000
177	S	A	0.0000
178	S	A	0.0000
179	Y	A	0.0000
180	L	A	1.6021
181	S	A	0.3439
182	L	A	-0.5094
183	T	A	-1.7615
184	P	A	-2.3515
185	E	A	-3.1235
186	Q	A	-2.2374
187	W	A	0.0000
188	K	A	-3.0722
189	S	A	0.0000
190	H	A	-2.5164
191	R	A	-2.6469
192	S	A	-1.6668
193	Y	A	0.0000
194	S	A	-1.0458
195	C	A	0.0000
196	Q	A	-1.0598
197	V	A	0.0000
198	T	A	-0.7205
199	H	A	0.0000
200	E	A	-2.3397
201	G	A	-1.4470
202	S	A	-0.9192
203	T	A	-0.8048
204	V	A	-0.7873
205	E	A	-2.1624
206	K	A	-1.7467
207	T	A	-1.0390
208	V	A	0.0000
209	A	A	-0.9512
210	P	A	-0.9171
2	V	A	1.0701
3	Q	A	-0.8590
4	L	A	0.0000
5	Q	A	-1.5265
6	Q	A	-1.1527
7	S	A	-1.1791
8	G	A	-1.2393
9	A	A	-0.8056
10	E	A	-1.2004
11	V	A	-0.7404
12	K	A	-1.6398
13	K	A	-2.3565
14	P	A	-1.9618
15	G	A	-1.4534
16	S	A	-1.1671
17	S	A	-1.3881
18	V	A	-1.5551
19	R	A	-2.4318
20	V	A	0.0000
21	S	A	-1.0251
22	C	A	0.0000
23	K	A	-1.4836
24	A	A	0.0000
25	S	A	-0.6630
26	G	A	-0.6186
27	G	A	-1.0865
28	T	A	-1.4993
29	F	A	0.0000
30	N	A	-1.9365
31	N	A	-1.0199
32	N	A	-1.0613
33	A	A	-0.2187
34	I	A	0.0000
35	N	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	R	A	-0.5433
39	Q	A	-0.7830
40	A	A	-1.0733
41	P	A	-0.8905
42	G	A	-1.3024
43	Q	A	-1.8108
44	G	A	-1.3013
45	L	A	0.0000
46	E	A	-0.8248
47	W	A	0.0000
48	M	A	0.0000
49	G	A	0.0000
50	G	A	0.0000
51	I	A	0.4355
52	I	A	0.0740
53	P	A	-0.5247
54	M	A	0.3449
55	F	A	1.7885
56	G	A	0.5543
57	T	A	-0.0119
58	A	A	-0.2046
59	K	A	-1.2342
60	Y	A	-0.6423
61	S	A	-1.2510
62	Q	A	-2.2028
63	N	A	-2.2198
64	F	A	0.0000
65	Q	A	-2.1760
66	G	A	-1.5288
67	R	A	-1.3199
68	V	A	0.0000
69	A	A	-0.8282
70	I	A	0.0000
71	T	A	-0.7119
72	A	A	-1.3205
73	D	A	-2.7464
74	E	A	-2.6302
75	S	A	-1.6754
76	T	A	-1.3528
77	G	A	0.0000
78	T	A	-1.5222
79	A	A	0.0000
80	S	A	0.0000
81	M	A	0.0000
82	E	A	-2.0638
83	L	A	0.0000
84	S	A	-1.2390
85	S	A	-1.1488
86	L	A	0.0000
87	R	A	-2.6031
88	S	A	-2.1584
89	E	A	-2.4401
90	D	A	0.0000
91	T	A	-0.8761
92	A	A	0.0000
93	V	A	0.0595
94	Y	A	0.0000
95	Y	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	-0.3976
99	S	A	0.0000
100	R	A	-0.9603
101	D	A	0.2267
102	L	A	1.2113
103	L	A	2.4005
104	L	A	2.2287
105	F	A	1.1818
106	P	A	0.5762
107	H	A	-0.7655
108	H	A	-0.6593
109	A	A	0.0000
110	L	A	0.0000
111	S	A	0.0424
112	P	A	0.0077
113	W	A	-0.2975
114	G	A	0.0000
115	R	A	-2.2949
116	G	A	-1.2297
117	T	A	0.0000
118	M	A	-0.2650
119	V	A	0.0000
120	T	A	0.0000
121	V	A	0.0000
122	S	A	-1.1026
123	S	A	-1.0041
124	A	A	-0.6126
125	S	A	-0.6607
126	T	A	-0.5685
127	K	A	-0.8641
128	G	A	-1.1683
129	P	A	-0.5666
130	S	A	-0.2766
131	V	A	0.0000
132	F	A	0.0000
133	P	A	-1.3619
134	L	A	0.0000
135	A	A	-0.7493
136	P	A	-0.8257
137	S	A	-0.7279
138	S	A	-1.2264
139	K	A	-2.0485
140	S	A	-1.4586
141	T	A	-0.8949
142	S	A	-0.8074
143	G	A	-1.1048
144	G	A	-1.1415
145	T	A	-0.8732
146	A	A	0.0000
147	A	A	-0.0802
148	L	A	0.0000
149	G	A	0.0000
150	C	A	0.0000
151	L	A	0.0000
152	V	A	0.0000
153	K	A	0.0000
154	D	A	-0.2998
155	Y	A	0.0000
156	F	A	-0.1448
157	P	A	0.0000
158	E	A	-0.6118
159	P	A	-0.8320
160	V	A	0.0000
161	T	A	-0.5390
162	V	A	-0.1706
163	S	A	-0.4364
164	W	A	0.0000
165	N	A	-0.9095
166	S	A	-0.6876
167	G	A	-0.4654
168	A	A	-0.2232
169	L	A	-0.0023
170	T	A	-0.1592
171	S	A	-0.2820
172	G	A	-0.3468
173	V	A	0.1550
174	H	A	-0.1141
175	T	A	0.0281
176	F	A	0.0000
177	P	A	-0.0668
178	A	A	0.2318
179	V	A	0.0000
180	L	A	1.2500
181	Q	A	0.2742
182	S	A	-0.1651
183	S	A	-0.2824
184	G	A	-0.1405
185	L	A	0.1441
186	Y	A	0.3913
187	S	A	0.0000
188	L	A	0.0000
189	S	A	0.0000
190	S	A	0.0000
191	V	A	0.1773
192	V	A	0.0000
193	T	A	-0.1918
194	V	A	0.0000
195	P	A	-0.4354
196	S	A	-0.9078
197	S	A	-0.7396
198	S	A	-0.5354
199	L	A	-0.8517
200	G	A	-0.9895
201	T	A	-0.8097
202	Q	A	-1.4738
203	T	A	-1.3422
204	Y	A	0.0000
205	I	A	-1.5887
206	C	A	0.0000
207	N	A	-1.6434
208	V	A	0.0000
209	N	A	-1.7781
210	H	A	0.0000
211	K	A	-2.4884
212	P	A	-1.5209
213	S	A	-1.6712
214	N	A	-2.3453
215	T	A	-1.9890
216	K	A	-2.6298
217	V	A	-1.6692
218	D	A	-2.7460
219	K	A	-2.3710
220	K	A	-2.7672
221	V	A	0.0000
222	E	A	-2.5452
223	P	A	-1.2307