Project name: 448c4f372341d8

Chain sequence(s)	A: MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.7825
• Maximal score value: 0.6326
• Average score: -1.1797
• Total score value: -123.8651

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	-0.1570
2	V	A	0.0000
3	K	A	-1.8991
4	Q	A	-2.3011
5	I	A	0.0000
6	E	A	-2.9494
7	S	A	-2.4711
8	K	A	-2.4118
9	T	A	-1.5898
10	A	A	-2.0068
11	F	A	0.0000
12	Q	A	-2.7494
13	E	A	-3.0778
14	A	A	-2.0361
15	L	A	-2.5776
16	D	A	-3.3885
17	A	A	-1.9622
18	A	A	0.0000
19	G	A	-2.2829
20	D	A	-2.8974
21	K	A	-1.5948
22	L	A	0.0000
23	V	A	0.0000
24	V	A	0.0000
25	V	A	0.0000
26	D	A	0.0000
27	F	A	0.0000
28	S	A	-0.5361
29	A	A	0.0000
30	T	A	-0.2399
31	W	A	0.6326
32	C	A	0.2124
33	G	A	-0.5232
34	P	A	-0.6254
35	C	A	0.0000
36	K	A	-1.4954
37	M	A	-0.2887
38	I	A	0.0000
39	K	A	-1.0394
40	P	A	-0.6029
41	F	A	-0.3019
42	F	A	0.0000
43	H	A	-1.0167
44	S	A	-1.1249
45	L	A	0.0000
46	S	A	0.0000
47	E	A	-2.5838
48	K	A	-2.6515
49	Y	A	-1.4813
50	S	A	-1.4013
51	N	A	-1.6347
52	V	A	0.0000
53	I	A	0.0688
54	F	A	0.0000
55	L	A	0.0000
56	E	A	-1.3997
57	V	A	0.0000
58	D	A	-2.2565
59	V	A	0.0000
60	D	A	-3.2396
61	D	A	-3.7825
62	C	A	0.0000
63	Q	A	-3.5276
64	D	A	-3.6032
65	V	A	0.0000
66	A	A	0.0000
67	S	A	-2.8488
68	E	A	-3.1629
69	C	A	-2.3948
70	E	A	-2.9655
71	V	A	0.0000
72	K	A	-1.8162
73	C	A	-0.2599
74	M	A	0.0826
75	P	A	0.0000
76	T	A	0.0000
77	F	A	0.0000
78	Q	A	0.0000
79	F	A	0.0000
80	F	A	0.0000
81	K	A	-2.3969
82	K	A	-3.5621
83	G	A	-2.9589
84	Q	A	-2.4014
85	K	A	-2.0195
86	V	A	-0.7576
87	G	A	-0.8850
88	E	A	-1.5158
89	F	A	-0.7916
90	S	A	-0.5677
91	G	A	-0.5387
92	A	A	-1.2532
93	N	A	-2.3295
94	K	A	-2.5343
95	E	A	-3.1194
96	K	A	-2.7004
97	L	A	0.0000
98	E	A	-2.0432
99	A	A	-1.9923
100	T	A	0.0000
101	I	A	0.0000
102	N	A	-1.6983
103	E	A	-1.8815
104	L	A	-0.2161
105	V	A	0.4590