Project name: 4cy2_modified_chains-AC.pdb_stat_DIBS

Chain sequence(s)	A: VKPNYALKFTLAGHTKAVSSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC; C: SDDLDVVGD
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9624
• Maximal score value: 0.7559
• Average score: -0.6012
• Total score value: -188.1871

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
31	V	A	0.7559
32	K	A	-1.3131
33	P	A	0.0000
34	N	A	-2.0811
35	Y	A	0.0000
36	A	A	-0.7055
37	L	A	-0.1301
38	K	A	-1.0349
39	F	A	-0.1569
40	T	A	-0.1851
41	L	A	0.0000
42	A	A	0.1200
43	G	A	-0.2051
44	H	A	0.0000
45	T	A	-0.9839
46	K	A	-1.8028
47	A	A	-1.4211
48	V	A	0.0000
49	S	A	-0.2737
50	S	A	0.0000
51	V	A	0.0000
52	K	A	-0.2265
53	F	A	0.0000
54	S	A	0.0000
55	P	A	-1.6437
56	N	A	-2.3624
57	G	A	0.0000
58	E	A	-2.0358
59	W	A	-1.0648
60	L	A	0.0000
61	A	A	0.0000
62	S	A	0.0000
63	S	A	0.0000
64	S	A	0.0000
65	A	A	-0.8036
66	D	A	-1.0061
67	K	A	-1.4612
68	L	A	-0.5806
69	I	A	0.0000
70	K	A	0.0000
71	I	A	0.0000
72	W	A	0.0000
73	G	A	-0.9037
74	A	A	0.0000
75	Y	A	-0.2915
76	D	A	-0.8700
77	G	A	0.0000
78	K	A	-1.1764
79	F	A	0.1718
80	E	A	-1.1437
81	K	A	-0.8600
82	T	A	-0.2793
83	I	A	0.0000
84	S	A	-0.9859
85	G	A	-1.2340
86	H	A	0.0000
87	K	A	-2.0605
88	L	A	-0.9990
89	G	A	-0.8989
90	I	A	0.0000
91	S	A	-0.0505
92	D	A	0.0000
93	V	A	0.0000
94	A	A	0.0000
95	W	A	0.0000
96	S	A	0.0000
97	S	A	-1.7006
98	D	A	-2.5339
99	S	A	0.0000
100	N	A	-1.6387
101	L	A	-0.7926
102	L	A	0.0000
103	V	A	0.0000
104	S	A	0.0000
105	A	A	0.0000
106	S	A	0.0000
107	D	A	-1.1345
108	D	A	-1.5943
109	K	A	-1.7736
110	T	A	0.0000
111	L	A	0.0000
112	K	A	-0.7632
113	I	A	0.0000
114	W	A	0.0000
115	D	A	-1.0329
116	V	A	0.0000
117	S	A	-0.8901
118	S	A	-1.0650
119	G	A	-1.2026
120	K	A	-1.8752
121	C	A	-0.8685
122	L	A	-0.6146
123	K	A	-1.4657
124	T	A	-1.0727
125	L	A	0.0000
126	K	A	-2.4504
127	G	A	-1.5886
128	H	A	0.0000
129	S	A	-1.0161
130	N	A	-0.8533
131	Y	A	-0.2839
132	V	A	0.0000
133	F	A	0.2616
134	C	A	0.0000
135	C	A	0.0000
136	N	A	-0.3357
137	F	A	0.0000
138	N	A	0.0000
139	P	A	-1.8413
140	Q	A	-2.1087
141	S	A	-1.4341
142	N	A	-1.4229
143	L	A	-0.6354
144	I	A	0.0000
145	V	A	0.0000
146	S	A	0.0000
147	G	A	0.0000
148	S	A	0.0000
149	F	A	-0.3271
150	D	A	-0.9969
151	E	A	-1.5280
152	S	A	0.0000
153	V	A	0.0000
154	R	A	-0.3675
155	I	A	0.0000
156	W	A	0.0000
157	D	A	-1.2006
158	V	A	0.0000
159	K	A	-2.2600
160	T	A	-1.5512
161	G	A	-1.7255
162	K	A	-2.1632
163	C	A	-0.7158
164	L	A	0.3203
165	K	A	-0.3668
166	T	A	-0.2567
167	L	A	0.0000
168	P	A	-0.6189
169	A	A	0.0000
170	H	A	0.0000
171	S	A	-1.0055
172	D	A	-1.3088
173	P	A	-0.6790
174	V	A	0.0000
175	S	A	0.0000
176	A	A	0.0000
177	V	A	0.0000
178	H	A	-0.5379
179	F	A	0.0000
180	N	A	0.0000
181	R	A	-2.8524
182	D	A	-2.5321
183	G	A	0.0000
184	S	A	-0.9081
185	L	A	-0.5496
186	I	A	0.0000
187	V	A	0.0000
188	S	A	0.0000
189	S	A	0.0000
190	S	A	0.0000
191	Y	A	-0.2805
192	D	A	-0.7948
193	G	A	0.0000
194	L	A	0.1546
195	C	A	0.0000
196	R	A	0.0286
197	I	A	0.0000
198	W	A	0.0000
199	D	A	-0.5537
200	T	A	-0.4327
201	A	A	-0.4008
202	S	A	-0.6777
203	G	A	-0.7778
204	Q	A	-0.9810
205	C	A	-0.0948
206	L	A	0.4306
207	K	A	0.0564
208	T	A	0.3671
209	L	A	0.0000
210	I	A	0.4550
211	D	A	-1.7052
212	D	A	-2.7597
213	D	A	-2.9054
214	N	A	-1.8118
215	P	A	-1.4055
216	P	A	-0.7059
217	V	A	0.0000
218	S	A	0.0000
219	F	A	0.0000
220	V	A	0.0000
221	K	A	-0.3738
222	F	A	0.0000
223	S	A	0.0000
224	P	A	-0.3849
225	N	A	0.0000
226	G	A	-1.1117
227	K	A	-1.6002
228	Y	A	0.0000
229	I	A	0.0000
230	L	A	0.0000
231	A	A	0.0000
232	A	A	0.0000
233	T	A	0.0000
234	L	A	-1.3114
235	D	A	-1.8918
236	N	A	-1.6537
237	T	A	-0.8620
238	L	A	0.0000
239	K	A	-0.2015
240	L	A	0.0000
241	W	A	0.0000
242	D	A	0.0000
243	Y	A	-1.0995
244	S	A	-1.4738
245	K	A	-2.3467
246	G	A	-1.4508
247	K	A	-1.7108
248	C	A	-0.4748
249	L	A	-0.2575
250	K	A	0.0000
251	T	A	-0.3673
252	Y	A	0.0000
253	T	A	-0.9063
254	G	A	-0.8084
255	H	A	0.0000
256	K	A	-1.9819
257	N	A	0.0000
258	E	A	-2.2766
259	K	A	-2.1262
260	Y	A	-0.4515
261	C	A	0.0450
262	I	A	0.0000
263	F	A	0.2800
264	A	A	0.0000
265	N	A	0.0000
266	F	A	0.3731
267	S	A	0.0000
268	V	A	0.4850
269	T	A	-0.2862
270	G	A	-0.8130
271	G	A	-0.5162
272	K	A	-0.4967
273	W	A	0.0000
274	I	A	0.0000
275	V	A	0.0000
276	S	A	0.0000
277	G	A	0.0000
278	S	A	0.0000
279	E	A	0.0000
280	D	A	-1.2585
281	N	A	-1.2892
282	L	A	-1.0920
283	V	A	0.0000
284	Y	A	0.0000
285	I	A	0.0000
286	W	A	0.0000
287	N	A	-1.0130
288	L	A	0.0000
289	Q	A	-1.8805
290	T	A	-1.5066
291	K	A	-1.5833
292	E	A	-1.7139
293	I	A	-0.6237
294	V	A	0.0000
295	Q	A	-1.2617
296	K	A	-1.3346
297	L	A	0.0000
298	Q	A	-1.6296
299	G	A	-0.9453
300	H	A	0.0000
301	T	A	-1.1465
302	D	A	-1.2711
303	V	A	0.0000
304	V	A	0.0000
305	I	A	0.0000
306	S	A	0.0000
307	T	A	0.0000
308	A	A	0.0000
309	C	A	-0.0055
310	H	A	0.0000
311	P	A	-0.8267
312	T	A	-0.7962
313	E	A	-1.2376
314	N	A	-1.2330
315	I	A	0.0000
316	I	A	0.0000
317	A	A	0.0000
318	S	A	0.0000
319	A	A	0.0000
320	A	A	0.0000
321	L	A	-1.2213
322	E	A	-2.2519
323	N	A	-2.2223
324	D	A	-1.6515
325	K	A	-1.4281
326	T	A	-0.7070
327	I	A	0.0000
328	K	A	0.0000
329	L	A	0.0000
330	W	A	0.0000
331	K	A	-1.1433
332	S	A	-1.9101
333	D	A	-2.4569
334	C	A	-1.2939
408	S	C	-1.6411
409	D	C	-2.8217
410	D	C	-2.9624
411	L	C	-1.6421
412	D	C	-2.0140
413	V	C	0.0000
414	V	C	0.4954
415	G	C	-0.8219
416	D	C	-1.9549