Project name: 4cdc002233f6a85

Chain sequence(s)	H: QLVQSGAEVKKPGASVKVSCKASGYTFTNYWINWVRQAPGQRLEWMGNIYPSDTYINHNQKFKDRVTITRDTSASTAYMELSSLRSEDTAVYYCARSAYANYFDYWGQGTLVT; L: DIVMTQSPATLSVSPGERATLSCRASQNIGTSIHWYQQKPGQAPRLLIYYASESISGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQSDSWPTLTFGQGTKLEIK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.7156
• Maximal score value: 1.461
• Average score: -0.5809
• Total score value: -128.3772

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	L	-1.5909
2	I	L	0.0000
3	V	L	0.9460
4	M	L	0.0000
5	T	L	-0.0669
6	Q	L	0.0000
7	S	L	-0.4367
8	P	L	-0.3863
9	A	L	-0.4272
10	T	L	-0.6355
11	L	L	-0.3087
12	S	L	-0.3978
13	V	L	-0.6856
14	S	L	-1.0132
15	P	L	-1.4324
16	G	L	-1.7142
17	E	L	-2.3665
18	R	L	-2.5787
19	A	L	0.0000
20	T	L	-0.5856
21	L	L	0.0000
22	S	L	-0.7001
23	C	L	0.0000
24	R	L	-1.5700
25	A	L	0.0000
26	S	L	-0.9767
27	Q	L	-2.3598
28	N	L	-2.5869
29	I	L	0.0000
30	G	L	-1.2303
31	T	L	-0.5036
32	S	L	-0.3106
33	I	L	0.0000
34	H	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	0.0000
39	K	L	-1.9680
40	P	L	-1.3222
41	G	L	-1.5087
42	Q	L	-2.2101
43	A	L	-1.4091
44	P	L	0.0000
45	R	L	-1.6153
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	0.3721
50	Y	L	0.9013
51	A	L	0.0000
52	S	L	-0.4246
53	E	L	-0.6240
54	S	L	-0.5088
55	I	L	-0.3602
56	S	L	-0.4970
57	G	L	-0.5550
58	I	L	0.0000
59	P	L	-0.3711
60	A	L	-0.3113
61	R	L	-0.7464
62	F	L	0.0000
63	S	L	-0.5177
64	G	L	-0.3601
65	S	L	-0.6356
66	G	L	-0.9808
67	S	L	-1.0753
68	G	L	-1.7893
69	T	L	-2.1669
70	E	L	-2.5766
71	F	L	0.0000
72	T	L	-0.7306
73	L	L	0.0000
74	T	L	-0.5934
75	I	L	0.0000
76	S	L	-1.3949
77	S	L	-1.6048
78	L	L	0.0000
79	Q	L	-1.7370
80	S	L	-1.2243
81	E	L	-2.2723
82	D	L	0.0000
83	F	L	-0.7702
84	A	L	0.0000
85	V	L	-0.5124
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	Q	L	0.0000
90	Q	L	0.0000
91	S	L	-0.3007
92	D	L	-1.6105
93	S	L	-0.9075
94	W	L	-0.1391
95	P	L	-0.6218
95A	T	L	-0.7568
96	L	L	0.0000
97	T	L	0.0290
98	F	L	0.0541
99	G	L	0.0000
100	Q	L	-0.9497
101	G	L	0.0000
102	T	L	0.0000
103	K	L	-1.2524
104	L	L	0.0000
105	E	L	-0.5308
106	I	L	0.6414
107	K	L	-0.9303
3	Q	H	-1.1732
4	L	H	0.0000
5	V	H	-0.0837
6	Q	H	0.0000
7	S	H	-0.6471
8	G	H	-0.6022
9	A	H	-0.0049
10	E	H	-0.6038
11	V	H	0.6325
12	K	H	-1.2520
13	K	H	-2.1700
14	P	H	-2.0518
15	G	H	-1.5901
16	A	H	-1.1333
17	S	H	-1.4056
18	V	H	0.0000
19	K	H	-2.1632
20	V	H	0.0000
21	S	H	-0.7153
22	C	H	0.0000
23	K	H	-1.3535
24	A	H	0.0000
25	S	H	-0.9021
26	G	H	-0.7776
27	Y	H	-0.3905
28	T	H	-0.4256
29	F	H	0.0000
30	T	H	-0.9395
31	N	H	-1.2173
32	Y	H	0.1690
33	W	H	0.5548
34	I	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.6897
40	A	H	0.0000
41	P	H	-1.3852
42	G	H	-1.6552
43	Q	H	-2.0642
44	R	H	-2.0330
45	L	H	0.0000
46	E	H	0.0000
47	W	H	0.0000
48	M	H	0.0000
49	G	H	0.0000
50	N	H	0.1806
51	I	H	0.0000
52	Y	H	0.0161
52A	P	H	0.0000
53	S	H	-1.1534
54	D	H	-1.4404
55	T	H	-0.2942
56	Y	H	0.9056
57	I	H	0.7877
58	N	H	-0.4373
59	H	H	-1.8078
60	N	H	-2.1317
61	Q	H	-3.2161
62	K	H	-3.1648
63	F	H	0.0000
64	K	H	-3.7156
65	D	H	-3.3207
66	R	H	-2.1980
67	V	H	0.0000
68	T	H	-1.1166
69	I	H	0.0000
70	T	H	-0.1522
71	R	H	-1.0413
72	D	H	-1.2517
73	T	H	-1.0155
74	S	H	-0.5405
75	A	H	-0.6962
76	S	H	-0.8960
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	-0.7800
80	M	H	0.0000
81	E	H	-1.5490
82	L	H	0.0000
82A	S	H	-1.2395
82B	S	H	-1.3145
82C	L	H	0.0000
83	R	H	-2.6853
84	S	H	-2.1748
85	E	H	-2.5394
86	D	H	0.0000
87	T	H	-0.6301
88	A	H	0.0000
89	V	H	0.5728
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0000
95	S	H	0.8194
96	A	H	0.8537
97	Y	H	1.4610
98	A	H	0.9279
99	N	H	0.0000
100	Y	H	0.8627
100A	F	H	0.0000
101	D	H	0.3117
102	Y	H	0.6290
103	W	H	0.0452
104	G	H	0.0000
105	Q	H	-1.1137
106	G	H	-0.3570
107	T	H	0.0000
108	L	H	0.8738
109	V	H	0.0000
110	T	H	-0.2839