| Chain sequence(s) |
A: QVQLQESGGGLVQPGGSLRLSCAASGFTLDYYYIGWFRQAPGKEREAVSCISGSSGSTYYPDSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCATIRSSSWGGCVHYGMDYWGKGTQVTVSS B: QVQLQESGGGLVQPGGSLRLSCAASGFTLDYYYIGWFRQAPGKEREAVSCISGSSGSTYYPDSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCATIRSSSWGGCVHYGMDYWGKGTQVTVSS |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | Q | A | -1.5260 | |
| 2 | V | A | -1.1392 | |
| 3 | Q | A | -1.5841 | |
| 4 | L | A | 0.0000 | |
| 5 | Q | A | -1.2326 | |
| 6 | E | A | 0.0000 | |
| 7 | S | A | -1.1108 | |
| 8 | G | A | -0.9721 | |
| 9 | G | A | -0.8429 | |
| 10 | G | A | -0.0272 | |
| 11 | L | A | 0.8956 | |
| 12 | V | A | 0.0000 | |
| 13 | Q | A | -1.4143 | |
| 14 | P | A | -1.6952 | |
| 15 | G | A | -1.4415 | |
| 16 | G | A | -0.9949 | |
| 17 | S | A | -1.4047 | |
| 18 | L | A | -1.1561 | |
| 19 | R | A | -2.2713 | |
| 20 | L | A | 0.0000 | |
| 21 | S | A | -0.9595 | |
| 22 | C | A | 0.0000 | |
| 23 | A | A | -0.8190 | |
| 24 | A | A | 0.0000 | |
| 25 | S | A | 0.0000 | |
| 26 | G | A | 0.0000 | |
| 27 | F | A | 0.0000 | |
| 28 | T | A | -0.5846 | |
| 29 | L | A | 0.0000 | |
| 30 | D | A | -1.1545 | |
| 31 | Y | A | 0.0333 | |
| 32 | Y | A | 0.0000 | |
| 33 | Y | A | -0.4380 | |
| 34 | I | A | 0.0000 | |
| 35 | G | A | 0.0000 | |
| 36 | W | A | 0.0000 | |
| 37 | F | A | 0.0000 | |
| 38 | R | A | 0.0000 | |
| 39 | Q | A | -1.7242 | |
| 40 | A | A | -1.5793 | |
| 41 | P | A | -1.2453 | |
| 42 | G | A | -1.3779 | |
| 43 | K | A | -2.0310 | |
| 44 | E | A | -2.7763 | |
| 45 | R | A | -2.2848 | |
| 46 | E | A | -1.5872 | |
| 47 | A | A | -0.4522 | |
| 48 | V | A | 0.0000 | |
| 49 | S | A | 0.0000 | |
| 50 | C | A | 0.0000 | |
| 51 | I | A | 0.0000 | |
| 52 | S | A | 0.0000 | |
| 52A | G | A | 0.0000 | |
| 53 | S | A | -0.7560 | |
| 54 | S | A | -0.6669 | |
| 55 | G | A | -0.7976 | |
| 56 | S | A | -0.2608 | |
| 57 | T | A | 0.1274 | |
| 58 | Y | A | 0.1676 | |
| 59 | Y | A | -0.6855 | |
| 60 | P | A | -1.3884 | |
| 61 | D | A | -2.4793 | |
| 62 | S | A | -1.6682 | |
| 63 | V | A | 0.0000 | |
| 64 | K | A | -2.6020 | |
| 65 | G | A | -1.8436 | |
| 66 | R | A | -1.5099 | |
| 67 | F | A | 0.0000 | |
| 68 | T | A | -1.0097 | |
| 69 | I | A | 0.0000 | |
| 70 | S | A | -0.6941 | |
| 71 | R | A | -1.2046 | |
| 72 | D | A | -1.2740 | |
| 73 | N | A | -1.6503 | |
| 74 | A | A | -0.9137 | |
| 75 | K | A | -1.2680 | |
| 76 | N | A | 0.0000 | |
| 77 | T | A | 0.0000 | |
| 78 | V | A | 0.0000 | |
| 79 | Y | A | -0.7386 | |
| 80 | L | A | 0.0000 | |
| 81 | Q | A | -1.7640 | |
| 82 | M | A | 0.0000 | |
| 82A | N | A | -1.5651 | |
| 82B | S | A | -1.2958 | |
| 82C | L | A | 0.0000 | |
| 83 | K | A | -2.5003 | |
| 84 | P | A | -1.9856 | |
| 85 | E | A | -2.3458 | |
| 86 | D | A | 0.0000 | |
| 87 | T | A | -0.9720 | |
| 88 | A | A | 0.0000 | |
| 89 | V | A | -0.6274 | |
| 90 | Y | A | 0.0000 | |
| 91 | Y | A | -0.5588 | |
| 92 | C | A | 0.0000 | |
| 93 | A | A | 0.0000 | |
| 94 | T | A | 0.0000 | |
| 95 | I | A | 0.0000 | |
| 96 | R | A | -2.0400 | |
| 97 | S | A | -0.9642 | |
| 98 | S | A | -0.7509 | |
| 99 | S | A | -1.1458 | |
| 100 | W | A | -0.7878 | |
| 100A | G | A | -0.4330 | |
| 100B | G | A | -0.0079 | |
| 100C | C | A | 0.2777 | |
| 100D | V | A | 0.2638 | |
| 100E | H | A | -0.4611 | |
| 100F | Y | A | 0.6638 | |
| 100G | G | A | -0.0337 | |
| 100H | M | A | -0.7346 | |
| 101 | D | A | -1.7344 | |
| 102 | Y | A | -0.8153 | |
| 103 | W | A | -0.6615 | |
| 104 | G | A | 0.0000 | |
| 105 | K | A | -1.8346 | |
| 106 | G | A | -1.1586 | |
| 107 | T | A | -1.1044 | |
| 108 | Q | A | -1.0659 | |
| 109 | V | A | 0.0000 | |
| 110 | T | A | -0.4275 | |
| 111 | V | A | 0.0000 | |
| 112 | S | A | -0.5230 | |
| 113 | S | A | -0.7097 | |
| 1 | Q | B | -1.5319 | |
| 2 | V | B | -1.1774 | |
| 3 | Q | B | -1.6597 | |
| 4 | L | B | 0.0000 | |
| 5 | Q | B | -1.5216 | |
| 6 | E | B | 0.0000 | |
| 7 | S | B | -1.1967 | |
| 8 | G | B | -1.1260 | |
| 9 | G | B | -0.8227 | |
| 10 | G | B | -0.1641 | |
| 11 | L | B | 0.9686 | |
| 12 | V | B | -0.1224 | |
| 13 | Q | B | -1.3440 | |
| 14 | P | B | -1.6479 | |
| 15 | G | B | -1.5181 | |
| 16 | G | B | -1.1112 | |
| 17 | S | B | -1.6716 | |
| 18 | L | B | -1.3574 | |
| 19 | R | B | -2.4928 | |
| 20 | L | B | 0.0000 | |
| 21 | S | B | -1.0556 | |
| 22 | C | B | 0.0000 | |
| 23 | A | B | -0.9619 | |
| 24 | A | B | 0.0000 | |
| 25 | S | B | -1.0902 | |
| 26 | G | B | 0.0000 | |
| 27 | F | B | 0.0000 | |
| 28 | T | B | 0.0000 | |
| 29 | L | B | 0.0000 | |
| 30 | D | B | -0.8957 | |
| 31 | Y | B | 0.1127 | |
| 32 | Y | B | 0.0000 | |
| 33 | Y | B | -0.1888 | |
| 34 | I | B | 0.0000 | |
| 35 | G | B | 0.0000 | |
| 36 | W | B | 0.0000 | |
| 37 | F | B | 0.0000 | |
| 38 | R | B | 0.0000 | |
| 39 | Q | B | -2.2258 | |
| 40 | A | B | -2.0797 | |
| 41 | P | B | -1.6435 | |
| 42 | G | B | -1.9844 | |
| 43 | K | B | -3.3447 | |
| 44 | E | B | -3.5180 | |
| 45 | R | B | -2.8301 | |
| 46 | E | B | -2.2790 | |
| 47 | A | B | -0.6526 | |
| 48 | V | B | 0.0000 | |
| 49 | S | B | 0.0000 | |
| 50 | C | B | 0.0000 | |
| 51 | I | B | 0.0000 | |
| 52 | S | B | 0.0000 | |
| 52A | G | B | 0.0000 | |
| 53 | S | B | -0.7128 | |
| 54 | S | B | -0.6499 | |
| 55 | G | B | -0.6033 | |
| 56 | S | B | -0.1610 | |
| 57 | T | B | 0.4635 | |
| 58 | Y | B | 0.8393 | |
| 59 | Y | B | -0.3877 | |
| 60 | P | B | -1.2638 | |
| 61 | D | B | -2.3822 | |
| 62 | S | B | -1.6674 | |
| 63 | V | B | 0.0000 | |
| 64 | K | B | -2.5013 | |
| 65 | G | B | -1.9621 | |
| 66 | R | B | -1.8117 | |
| 67 | F | B | 0.0000 | |
| 68 | T | B | -1.0922 | |
| 69 | I | B | 0.0000 | |
| 70 | S | B | -0.6807 | |
| 71 | R | B | -1.0208 | |
| 72 | D | B | -1.0995 | |
| 73 | N | B | -1.3573 | |
| 74 | A | B | -0.7570 | |
| 75 | K | B | -1.2401 | |
| 76 | N | B | 0.0000 | |
| 77 | T | B | 0.0000 | |
| 78 | V | B | 0.0000 | |
| 79 | Y | B | -0.8244 | |
| 80 | L | B | 0.0000 | |
| 81 | Q | B | -2.1115 | |
| 82 | M | B | 0.0000 | |
| 82A | N | B | -2.3246 | |
| 82B | S | B | -1.5414 | |
| 82C | L | B | 0.0000 | |
| 83 | K | B | -2.3496 | |
| 84 | P | B | -1.9501 | |
| 85 | E | B | -2.3400 | |
| 86 | D | B | 0.0000 | |
| 87 | T | B | -0.9580 | |
| 88 | A | B | 0.0000 | |
| 89 | V | B | -0.7072 | |
| 90 | Y | B | 0.0000 | |
| 91 | Y | B | -0.6774 | |
| 92 | C | B | 0.0000 | |
| 93 | A | B | 0.0000 | |
| 94 | T | B | 0.0000 | |
| 95 | I | B | 0.0000 | |
| 96 | R | B | -1.6404 | |
| 97 | S | B | -0.7126 | |
| 98 | S | B | -0.6189 | |
| 99 | S | B | -1.0170 | |
| 100 | W | B | -0.6268 | |
| 100A | G | B | -0.3687 | |
| 100B | G | B | 0.0606 | |
| 100C | C | B | 0.0000 | |
| 100D | V | B | 0.1132 | |
| 100E | H | B | -0.5497 | |
| 100F | Y | B | 0.6429 | |
| 100G | G | B | -0.1976 | |
| 100H | M | B | 0.0000 | |
| 101 | D | B | -1.6759 | |
| 102 | Y | B | -0.7606 | |
| 103 | W | B | -0.6841 | |
| 104 | G | B | 0.0000 | |
| 105 | K | B | -1.9120 | |
| 106 | G | B | -1.2394 | |
| 107 | T | B | 0.0000 | |
| 108 | Q | B | -1.0808 | |
| 109 | V | B | 0.0000 | |
| 110 | T | B | -0.3588 | |
| 111 | V | B | 0.0000 | |
| 112 | S | B | -0.5781 | |
| 113 | S | B | -0.4488 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine