Project name: 70045695085ce16

Chain sequence(s)	H: DILMTQSPSSMSVSLGDTVSITCHASQGISSNIGWLQQKPGKSFKGLIYYGTNLVDGVPSRFSGSGSGADYSLTISSLESEDFADYYCVQYAQLPYTFGGGTKLEIKEVQLQQSGAELVKPGASVKLSCTASGFNIKDTYVHWVKQRPEQGLEWIGRIDPANGYTKYDPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYYCVRPLYDYYAMDYWGQGTSVTVSS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9023
• Maximal score value: 1.5297
• Average score: -0.6072
• Total score value: -137.2321

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	H	-1.7558
2	I	H	0.0000
3	L	H	0.6717
4	M	H	0.1673
5	T	H	-0.2847
6	Q	H	0.0000
7	S	H	-0.6356
8	P	H	-0.5644
9	S	H	-0.7809
10	S	H	-1.1545
11	M	H	-0.7738
12	S	H	-0.8179
13	V	H	-0.3410
14	S	H	-0.2934
15	L	H	0.1832
16	G	H	-0.6581
17	D	H	-0.9119
18	T	H	-0.6872
19	V	H	0.0000
20	S	H	-0.2112
21	I	H	0.0000
22	T	H	-0.6873
23	C	H	0.0000
24	H	H	-1.4238
25	A	H	-0.9194
26	S	H	-0.9248
27	Q	H	-1.9412
28	G	H	-1.7674
29	I	H	0.0000
30	S	H	-0.8698
31	S	H	-0.4647
32	N	H	-0.2350
33	I	H	0.0000
34	G	H	0.0000
35	W	H	0.0000
36	L	H	0.0000
37	Q	H	0.0000
38	Q	H	0.0000
39	K	H	-1.9112
40	P	H	-1.6357
41	G	H	-1.5160
42	K	H	-2.5050
43	S	H	-1.6607
44	F	H	0.0000
45	K	H	-1.1319
46	G	H	0.0000
47	L	H	0.0000
48	I	H	0.0000
49	Y	H	0.6175
50	Y	H	0.8174
51	G	H	0.0000
52	T	H	-0.1341
53	N	H	-0.3073
54	L	H	-0.3081
55	V	H	0.0000
56	D	H	-1.7990
57	G	H	-1.4219
58	V	H	0.0000
59	P	H	-0.6775
60	S	H	-0.4847
61	R	H	-0.7816
62	F	H	0.0000
63	S	H	-0.4389
64	G	H	-0.2466
65	S	H	-0.7181
66	G	H	-1.3118
67	S	H	-1.3619
68	G	H	-1.7149
69	A	H	-2.0244
70	D	H	-2.6116
71	Y	H	0.0000
72	S	H	-0.7875
73	L	H	0.0000
74	T	H	-0.3114
75	I	H	0.0000
76	S	H	-0.9186
77	S	H	-0.9513
78	L	H	0.0000
79	E	H	-2.0837
80	S	H	-1.4757
81	E	H	-2.3887
82	D	H	0.0000
83	F	H	0.0000
84	A	H	0.0000
85	D	H	-1.2227
86	Y	H	0.0000
87	Y	H	0.0000
88	C	H	0.0000
89	V	H	0.0000
90	Q	H	0.0000
91	Y	H	0.0000
92	A	H	-0.7629
93	Q	H	-1.1175
94	L	H	-0.6720
95	P	H	-0.7583
96	Y	H	0.0000
97	T	H	-0.0563
98	F	H	0.0000
99	G	H	0.0000
100	G	H	-1.1687
101	G	H	-0.9569
102	T	H	0.0000
103	K	H	-2.0377
104	L	H	0.0000
105	E	H	-1.5753
106	I	H	0.0822
107	K	H	-1.1104
108	E	H	-1.9093
109	V	H	-1.1062
110	Q	H	-1.3715
111	L	H	0.0000
112	Q	H	-1.4262
113	Q	H	0.0000
114	S	H	-1.0301
115	G	H	-1.0348
116	A	H	-0.4475
117	E	H	-0.7850
118	L	H	0.6137
119	V	H	-0.3806
120	K	H	-1.6382
121	P	H	-1.3485
122	G	H	-1.0945
123	A	H	-0.7097
124	S	H	-0.9066
125	V	H	0.0000
126	K	H	-2.0973
127	L	H	0.0000
128	S	H	-0.6226
129	C	H	0.0000
130	T	H	-0.7617
131	A	H	0.0000
132	S	H	-1.1597
133	G	H	-1.2677
134	F	H	-1.5699
135	N	H	-2.3370
136	I	H	0.0000
137	K	H	-2.8456
138	D	H	-2.6641
139	T	H	-0.9254
140	Y	H	-0.0802
141	V	H	0.0000
142	H	H	0.0000
143	W	H	0.0000
144	V	H	0.0000
145	K	H	0.0000
146	Q	H	-0.7808
147	R	H	-1.6405
148	P	H	-1.6547
149	E	H	-2.9023
150	Q	H	-2.6583
151	G	H	0.0000
152	L	H	0.0000
153	E	H	-1.0126
154	W	H	0.0000
155	I	H	0.0000
156	G	H	0.0000
157	R	H	-0.4370
158	I	H	0.0000
159	D	H	-1.0290
160	P	H	0.0000
161	A	H	-1.5277
162	N	H	-1.2980
163	G	H	-0.6284
164	Y	H	0.4168
165	T	H	-0.3323
166	K	H	-1.2414
167	Y	H	-1.2852
168	D	H	0.0000
169	P	H	-1.7710
170	K	H	-2.2682
171	F	H	0.0000
172	Q	H	-2.1981
173	G	H	-1.4694
174	K	H	-1.3680
175	A	H	0.0000
176	T	H	-0.9256
177	I	H	0.0000
178	T	H	-0.1183
179	A	H	-0.6105
180	D	H	-0.9484
181	T	H	-1.4577
182	S	H	-0.8404
183	S	H	-0.7065
184	N	H	-1.1439
185	T	H	0.0000
186	A	H	0.0000
187	Y	H	-0.3502
188	L	H	0.0000
189	Q	H	-1.3324
190	L	H	0.0000
191	S	H	-0.8781
192	S	H	-0.8243
193	L	H	0.0000
194	T	H	-1.2709
195	S	H	-1.4572
196	E	H	-2.3529
197	D	H	0.0000
198	T	H	-0.4578
199	A	H	0.0000
200	V	H	0.1005
201	Y	H	0.0000
202	Y	H	0.0000
203	C	H	0.0000
204	V	H	0.0000
205	R	H	0.0825
206	P	H	0.0000
207	L	H	0.6573
208	Y	H	1.4325
209	D	H	1.0461
210	Y	H	1.5297
211	Y	H	0.0000
212	A	H	0.0000
213	M	H	0.0000
214	D	H	0.0000
215	Y	H	-0.2124
216	W	H	0.0000
217	G	H	0.0000
218	Q	H	-1.8885
219	G	H	-1.0504
220	T	H	0.0000
221	S	H	-0.2641
222	V	H	0.0000
223	T	H	-0.1948
224	V	H	0.0000
225	S	H	-0.5176
226	S	H	-0.6625