Project name: 74468d275de094b
Status: done
submitted: 2019-01-11 12:56:46, status changed: 2019-01-11 13:14:44
Settings
Chain sequence(s)
|
A: SKGEELFTGKVPILVEELDGDVNGHKFSVSSSGEGEGDATKGKLTLKFICTTGKLPVPWPTLVTTLVQCFSRYPDHMKRHDFFKSAMPEGYVQERTISFKDDGNYKTRRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSSHHNVYITADKQKNGIKANFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLKEFFVTAAGIT
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.2334
-
Maximal score value
-
0.3239
-
Average score
-
-1.0696
-
Total score value
-
-241.7329
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
2 |
S |
A |
-1.9652 |
|
3 |
K |
A |
-2.4282 |
|
4 |
G |
A |
0.0000 |
|
5 |
E |
A |
-1.9763 |
|
6 |
E |
A |
-2.3898 |
|
7 |
L |
A |
-1.1869 |
|
8 |
F |
A |
0.0000 |
|
9 |
T |
A |
-1.1591 |
|
10 |
G |
A |
-1.5013 |
|
11 |
K |
A |
-2.2651 |
|
12 |
V |
A |
0.0000 |
|
13 |
P |
A |
-1.4508 |
|
14 |
I |
A |
0.0000 |
|
15 |
L |
A |
-1.0601 |
|
16 |
V |
A |
0.0000 |
|
17 |
E |
A |
-2.0201 |
|
18 |
L |
A |
0.0000 |
|
19 |
D |
A |
-3.4826 |
|
20 |
G |
A |
0.0000 |
|
21 |
D |
A |
-3.0438 |
|
22 |
V |
A |
0.0000 |
|
23 |
N |
A |
-2.1037 |
|
24 |
G |
A |
-1.7524 |
|
25 |
H |
A |
-2.2611 |
|
26 |
K |
A |
-3.0589 |
|
27 |
F |
A |
0.0000 |
|
28 |
S |
A |
-1.7842 |
|
29 |
V |
A |
0.0000 |
|
30 |
S |
A |
-1.0531 |
|
31 |
G |
A |
0.0000 |
|
32 |
E |
A |
-2.1794 |
|
33 |
G |
A |
-1.7659 |
|
34 |
E |
A |
-1.8345 |
|
35 |
G |
A |
0.0000 |
|
36 |
D |
A |
0.0000 |
|
37 |
A |
A |
0.0000 |
|
38 |
T |
A |
-1.6082 |
|
39 |
K |
A |
-2.2176 |
|
40 |
G |
A |
0.0000 |
|
41 |
K |
A |
-1.6316 |
|
42 |
L |
A |
0.0000 |
|
43 |
T |
A |
-1.0826 |
|
44 |
L |
A |
0.0000 |
|
45 |
K |
A |
-1.3631 |
|
46 |
F |
A |
0.0000 |
|
47 |
I |
A |
-1.1255 |
|
48 |
C |
A |
0.0000 |
|
49 |
T |
A |
-0.7949 |
|
50 |
T |
A |
-1.1918 |
|
51 |
G |
A |
-1.7137 |
|
52 |
K |
A |
-2.3099 |
|
53 |
L |
A |
0.0000 |
|
54 |
P |
A |
-1.1992 |
|
55 |
V |
A |
0.0000 |
|
56 |
P |
A |
0.0000 |
|
57 |
W |
A |
0.0000 |
|
58 |
P |
A |
0.0000 |
|
59 |
T |
A |
0.0000 |
|
60 |
L |
A |
0.0000 |
|
61 |
V |
A |
0.0000 |
|
62 |
T |
A |
-0.0041 |
|
63 |
T |
A |
0.0000 |
|
64 |
L |
A |
0.0000 |
|
68 |
V |
A |
-0.0838 |
|
69 |
Q |
A |
-0.1867 |
|
70 |
C |
A |
0.0000 |
|
71 |
F |
A |
0.0000 |
|
72 |
S |
A |
0.0000 |
|
73 |
R |
A |
-1.7646 |
|
74 |
Y |
A |
0.0000 |
|
75 |
P |
A |
-1.8117 |
|
76 |
D |
A |
-2.8657 |
|
77 |
H |
A |
-2.3095 |
|
78 |
M |
A |
0.0000 |
|
79 |
K |
A |
-2.7614 |
|
80 |
R |
A |
-2.7562 |
|
81 |
H |
A |
-1.7254 |
|
82 |
D |
A |
0.0000 |
|
83 |
F |
A |
0.0000 |
|
84 |
F |
A |
0.0000 |
|
85 |
K |
A |
0.0000 |
|
86 |
S |
A |
-1.1498 |
|
87 |
A |
A |
0.0000 |
|
88 |
M |
A |
0.0000 |
|
89 |
P |
A |
-1.5094 |
|
90 |
E |
A |
-1.9616 |
|
91 |
G |
A |
0.0000 |
|
92 |
Y |
A |
0.0000 |
|
93 |
V |
A |
-0.8622 |
|
94 |
Q |
A |
0.0000 |
|
95 |
E |
A |
-1.9043 |
|
96 |
R |
A |
0.0000 |
|
97 |
T |
A |
-0.9887 |
|
98 |
I |
A |
0.0000 |
|
99 |
S |
A |
-1.0465 |
|
100 |
F |
A |
0.0000 |
|
101 |
K |
A |
-2.1272 |
|
102 |
D |
A |
-2.7995 |
|
103 |
D |
A |
-2.6120 |
|
104 |
G |
A |
0.0000 |
|
105 |
N |
A |
-1.4892 |
|
106 |
Y |
A |
0.0000 |
|
107 |
K |
A |
-2.4737 |
|
108 |
T |
A |
0.0000 |
|
109 |
R |
A |
-3.5209 |
|
110 |
A |
A |
0.0000 |
|
111 |
E |
A |
-2.1706 |
|
112 |
V |
A |
0.0000 |
|
113 |
K |
A |
-1.3513 |
|
114 |
F |
A |
-1.4127 |
|
115 |
E |
A |
-1.6417 |
|
116 |
G |
A |
-1.7092 |
|
117 |
D |
A |
-2.1173 |
|
118 |
T |
A |
-1.5289 |
|
119 |
L |
A |
0.0000 |
|
120 |
V |
A |
0.0000 |
|
121 |
N |
A |
0.0000 |
|
122 |
R |
A |
-2.4443 |
|
123 |
I |
A |
0.0000 |
|
124 |
E |
A |
-4.2334 |
|
125 |
L |
A |
0.0000 |
|
126 |
K |
A |
-3.4230 |
|
127 |
G |
A |
0.0000 |
|
128 |
I |
A |
-1.2041 |
|
129 |
D |
A |
-2.2197 |
|
130 |
F |
A |
0.0000 |
|
131 |
K |
A |
-3.8179 |
|
132 |
E |
A |
-3.8235 |
|
133 |
D |
A |
-3.3636 |
|
134 |
G |
A |
-2.6536 |
|
135 |
N |
A |
-2.0742 |
|
136 |
I |
A |
0.0000 |
|
137 |
L |
A |
-1.6815 |
|
138 |
G |
A |
-1.8626 |
|
139 |
H |
A |
-1.3973 |
|
140 |
K |
A |
-1.9796 |
|
141 |
L |
A |
-1.4869 |
|
142 |
E |
A |
-1.7552 |
|
143 |
Y |
A |
-0.4712 |
|
144 |
N |
A |
-0.5365 |
|
145 |
Y |
A |
-0.8067 |
|
146 |
N |
A |
-1.2166 |
|
147 |
S |
A |
-1.2983 |
|
148 |
H |
A |
-1.4900 |
|
149 |
N |
A |
-1.3542 |
|
150 |
V |
A |
0.0000 |
|
151 |
Y |
A |
0.3239 |
|
152 |
I |
A |
0.0000 |
|
153 |
T |
A |
-1.2562 |
|
154 |
A |
A |
-1.8806 |
|
155 |
D |
A |
-2.4868 |
|
156 |
K |
A |
-3.1364 |
|
157 |
Q |
A |
-3.1931 |
|
158 |
K |
A |
-3.4014 |
|
159 |
N |
A |
-2.4860 |
|
160 |
G |
A |
0.0000 |
|
161 |
I |
A |
0.0000 |
|
162 |
K |
A |
-1.2435 |
|
163 |
A |
A |
0.0000 |
|
164 |
N |
A |
-1.0912 |
|
165 |
F |
A |
0.0000 |
|
166 |
K |
A |
-2.0300 |
|
167 |
I |
A |
0.0000 |
|
168 |
R |
A |
-1.7455 |
|
169 |
H |
A |
0.0000 |
|
170 |
N |
A |
-1.4772 |
|
171 |
I |
A |
0.0000 |
|
172 |
E |
A |
-3.2106 |
|
173 |
D |
A |
-3.0178 |
|
174 |
G |
A |
-1.9396 |
|
175 |
S |
A |
-1.0886 |
|
176 |
V |
A |
-0.5234 |
|
177 |
Q |
A |
0.0000 |
|
178 |
L |
A |
-1.1806 |
|
179 |
A |
A |
0.0000 |
|
180 |
D |
A |
-1.1732 |
|
181 |
H |
A |
0.0000 |
|
182 |
Y |
A |
0.0201 |
|
183 |
Q |
A |
0.0000 |
|
184 |
Q |
A |
-1.4375 |
|
185 |
N |
A |
0.0000 |
|
186 |
T |
A |
-0.8703 |
|
187 |
P |
A |
-0.8619 |
|
188 |
I |
A |
-0.2555 |
|
189 |
G |
A |
-1.2176 |
|
190 |
D |
A |
-2.0908 |
|
191 |
G |
A |
-1.5002 |
|
192 |
P |
A |
-0.9799 |
|
193 |
V |
A |
-0.5515 |
|
194 |
L |
A |
-0.2697 |
|
195 |
L |
A |
-0.1729 |
|
196 |
P |
A |
0.0000 |
|
197 |
D |
A |
-2.4528 |
|
198 |
N |
A |
-1.7881 |
|
199 |
H |
A |
0.0000 |
|
200 |
Y |
A |
-0.0970 |
|
201 |
L |
A |
0.0000 |
|
202 |
S |
A |
-0.6838 |
|
203 |
T |
A |
-0.8605 |
|
204 |
Q |
A |
-1.4751 |
|
205 |
S |
A |
-0.9203 |
|
206 |
A |
A |
-0.5023 |
|
207 |
L |
A |
-0.4003 |
|
208 |
S |
A |
-0.9306 |
|
209 |
K |
A |
-1.8712 |
|
210 |
D |
A |
-2.1850 |
|
211 |
P |
A |
-1.8176 |
|
212 |
N |
A |
-2.4723 |
|
213 |
E |
A |
-2.6445 |
|
214 |
K |
A |
-3.1045 |
|
215 |
R |
A |
-3.2835 |
|
216 |
D |
A |
-2.2427 |
|
217 |
H |
A |
0.0000 |
|
218 |
M |
A |
0.0000 |
|
219 |
V |
A |
-0.8899 |
|
220 |
L |
A |
0.0000 |
|
221 |
K |
A |
-1.1860 |
|
222 |
E |
A |
-0.7034 |
|
223 |
F |
A |
-0.2979 |
|
224 |
V |
A |
0.0000 |
|
225 |
T |
A |
-0.8113 |
|
226 |
A |
A |
0.0000 |
|
227 |
A |
A |
-0.3384 |
|
228 |
G |
A |
-0.4945 |
|
229 |
I |
A |
-0.4833 |
|
230 |
T |
A |
-0.1703 |
|