Project name: 796291bcc7d4038

Chain sequence(s)	A: DFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLELVSSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRASVTLGCAADVQPVQTGLDLLDILQQVKSQGEEAVGELPRGKLYSLGKGRWMLSLTKKMEEVKAIFTGYYG
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.9544
• Maximal score value: 1.2179
• Average score: -1.0552
• Total score value: -225.8072

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
163	D	A	-0.9412
164	F	A	0.7385
165	L	A	0.4483
166	P	A	0.0000
167	L	A	0.6466
168	Y	A	0.0000
169	F	A	0.0000
170	G	A	0.0000
171	W	A	0.0000
172	F	A	0.2897
173	L	A	0.0000
174	T	A	-1.3780
175	K	A	-2.5217
176	K	A	-2.8015
177	S	A	-2.1900
178	S	A	0.0000
179	E	A	-2.1266
180	T	A	-1.9382
181	L	A	0.0000
182	R	A	-2.0976
183	K	A	-2.1561
184	A	A	0.0000
185	G	A	0.0000
186	Q	A	-1.1588
187	V	A	-0.5075
188	F	A	0.0000
189	L	A	0.0000
190	E	A	-1.8700
191	E	A	-1.8117
192	L	A	0.0000
193	G	A	0.0000
194	N	A	-2.9656
195	H	A	-2.4639
196	K	A	-2.7444
197	A	A	-1.6989
198	F	A	0.0000
199	K	A	-3.4906
200	K	A	-3.0184
201	E	A	-2.5183
202	L	A	-2.6168
203	R	A	-3.2294
204	H	A	-2.2679
205	F	A	0.0000
206	I	A	-1.4022
207	S	A	-1.4196
208	G	A	-2.0317
209	D	A	-3.0386
210	E	A	-3.3461
211	P	A	-2.9801
212	K	A	-3.7676
213	E	A	-3.9544
214	K	A	-3.7741
215	L	A	-2.5382
216	E	A	-2.6720
217	L	A	0.0000
218	V	A	-0.8424
219	S	A	-0.6916
220	Y	A	-0.5253
221	F	A	0.0000
222	G	A	-1.1511
223	K	A	-2.3549
224	R	A	-2.4576
225	P	A	-1.2998
226	P	A	-0.8831
227	G	A	-0.7160
228	V	A	-0.0780
229	L	A	0.0000
230	H	A	0.1545
231	C	A	0.0000
232	T	A	0.3112
233	T	A	0.0000
234	K	A	0.0000
235	F	A	0.5774
236	C	A	0.0000
237	D	A	-0.7368
238	Y	A	-0.0324
239	G	A	-1.2479
240	K	A	-1.8333
241	A	A	-1.1720
242	A	A	-1.1422
243	G	A	-1.4714
244	A	A	0.0000
245	E	A	-3.0848
246	E	A	-3.2647
247	Y	A	0.0000
248	A	A	-2.4761
249	Q	A	-3.2849
250	Q	A	-3.4253
251	E	A	-3.2498
252	V	A	-2.2514
253	V	A	0.0000
254	K	A	-3.2593
255	R	A	-3.1853
256	S	A	0.0000
257	Y	A	-1.0247
258	G	A	-1.1487
259	K	A	-1.6875
260	A	A	-0.9629
261	F	A	-1.4697
262	K	A	-2.3606
263	L	A	0.0000
264	S	A	-1.5267
265	I	A	0.0000
266	S	A	-1.0342
267	A	A	0.0000
268	L	A	0.0000
269	F	A	0.0000
270	V	A	0.0000
271	T	A	0.0000
272	P	A	-0.8262
273	K	A	-1.5060
274	T	A	0.0000
275	A	A	0.0000
276	G	A	0.0000
277	A	A	0.0000
278	Q	A	-0.0416
279	V	A	0.0000
280	V	A	0.5497
281	L	A	-0.3866
282	T	A	-1.2888
283	D	A	-2.3873
284	Q	A	-2.2094
285	E	A	0.0000
286	L	A	-1.0578
287	Q	A	-1.7205
288	L	A	0.0000
289	W	A	-0.3939
290	P	A	-0.5278
291	S	A	-0.8610
292	D	A	-0.8742
293	L	A	0.1161
294	D	A	-1.8179
295	K	A	-2.1854
296	P	A	-1.3352
297	S	A	-1.4851
298	A	A	-1.3075
299	S	A	-1.7115
300	E	A	-2.4094
301	G	A	-1.6909
302	L	A	-1.2502
303	P	A	-0.7833
304	P	A	-0.8307
305	G	A	-0.2601
306	S	A	-0.3512
307	R	A	-0.5446
308	A	A	0.0000
309	S	A	-0.0438
310	V	A	0.0000
311	T	A	-0.2738
312	L	A	-1.0021
313	G	A	0.0000
314	C	A	0.0000
315	A	A	-1.4933
316	A	A	-1.3875
317	D	A	-2.2160
318	V	A	-1.5632
319	Q	A	-1.4941
320	P	A	-0.5741
321	V	A	1.0310
322	Q	A	-0.0163
323	T	A	0.0000
324	G	A	0.0707
325	L	A	0.2282
326	D	A	0.0000
327	L	A	0.0000
328	L	A	0.0000
329	D	A	-1.6733
330	I	A	0.0000
331	L	A	-1.1045
332	Q	A	-2.0654
333	Q	A	-2.0039
334	V	A	-1.6897
335	K	A	-2.3813
338	S	A	-1.4855
339	Q	A	-2.2560
340	G	A	-1.7880
341	E	A	-2.1986
342	A	A	-1.2630
343	V	A	-0.2026
344	G	A	-1.1739
345	E	A	-2.2292
346	L	A	-1.6664
347	P	A	-1.3566
348	R	A	-2.1083
349	G	A	0.0000
350	K	A	-2.0522
351	L	A	0.0000
352	Y	A	0.0000
353	S	A	-0.4301
354	L	A	-0.6162
355	G	A	-1.3230
356	K	A	-2.2233
357	G	A	0.0000
358	R	A	-1.0873
359	W	A	0.0000
360	M	A	0.0000
361	L	A	0.0000
362	S	A	-1.2625
363	L	A	0.0000
364	T	A	-1.8111
365	K	A	-2.9623
366	K	A	-2.9781
367	M	A	-2.2625
368	E	A	-3.0730
369	V	A	0.0000
370	K	A	-2.3475
371	A	A	0.0000
372	I	A	-0.2773
373	F	A	0.0000
374	T	A	-0.0170
375	G	A	0.8529
376	Y	A	1.2179
377	Y	A	1.0694
378	G	A	0.1387