Project name: 79b0daf3561db47

Chain sequence(s)	A: RMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLEIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.0596
• Maximal score value: 1.6536
• Average score: -0.8593
• Total score value: -181.3048

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1649	R	A	-2.0377
1650	M	A	-1.1371
1651	S	A	-0.9220
1652	M	A	0.0000
1653	V	A	0.0000
1654	V	A	0.0000
1655	S	A	0.0000
1656	G	A	-1.0581
1657	L	A	-0.5854
1658	T	A	-0.8275
1659	P	A	-0.9227
1660	E	A	-1.4979
1661	E	A	-0.8377
1662	F	A	-0.1855
1663	M	A	0.3272
1664	L	A	0.0936
1665	V	A	0.0000
1666	Y	A	-0.3375
1667	K	A	-1.6545
1668	F	A	0.0000
1669	A	A	0.0000
1670	R	A	-3.2658
1671	K	A	-3.2664
1672	H	A	-2.4410
1673	H	A	-2.3794
1674	I	A	0.0000
1675	T	A	-0.6824
1676	L	A	-0.1335
1677	T	A	-0.0123
1678	N	A	-0.4602
1679	L	A	0.9036
1680	I	A	0.0000
1681	T	A	-1.3207
1682	E	A	-2.7332
1683	E	A	-2.9784
1684	T	A	0.0000
1685	T	A	-1.1177
1686	H	A	0.0000
1687	V	A	0.0000
1688	V	A	0.0000
1689	M	A	0.0000
1690	K	A	-1.0593
1691	T	A	0.0000
1692	D	A	-1.2621
1693	A	A	-1.0728
1694	E	A	-2.5777
1695	F	A	-1.7308
1696	V	A	0.0000
1697	C	A	0.0000
1698	E	A	-1.4193
1699	R	A	-0.6375
1700	T	A	-0.8435
1701	L	A	-0.3569
1702	K	A	-0.0590
1703	Y	A	0.0000
1704	F	A	0.0000
1705	L	A	0.0000
1706	E	A	0.0000
1707	I	A	0.0000
1708	A	A	0.0000
1709	G	A	-0.8737
1710	G	A	-1.0609
1711	K	A	-0.8344
1712	W	A	-0.4161
1713	V	A	0.0000
1714	V	A	0.0000
1715	S	A	0.0000
1716	Y	A	0.0000
1717	F	A	0.0931
1718	W	A	0.0000
1719	V	A	0.0000
1720	T	A	-0.7940
1721	Q	A	-1.7518
1722	S	A	0.0000
1723	I	A	-2.3085
1724	K	A	-3.4481
1725	E	A	-4.0596
1726	R	A	-3.9053
1727	K	A	-3.3752
1728	M	A	-1.4543
1729	L	A	-1.6710
1730	N	A	-2.1991
1731	E	A	-1.8368
1732	H	A	-2.5055
1733	D	A	-2.6910
1734	F	A	0.0000
1735	E	A	-1.6790
1736	V	A	0.0000
1737	R	A	-2.9445
1738	G	A	0.0000
1739	D	A	0.0000
1740	V	A	1.3731
1741	V	A	1.6536
1742	N	A	0.1696
1743	G	A	-0.9023
1744	R	A	-2.5544
1745	N	A	-3.0148
1746	H	A	-2.0339
1747	Q	A	-2.2737
1748	G	A	0.0000
1749	P	A	0.0000
1750	K	A	-2.3766
1751	R	A	-2.2552
1752	A	A	0.0000
1753	R	A	-2.1877
1754	E	A	-3.2271
1755	S	A	-3.0258
1756	Q	A	-2.7889
1757	D	A	-3.5802
1758	R	A	-3.6768
1759	K	A	-2.9174
1760	I	A	-1.4962
1761	F	A	0.0000
1762	R	A	-2.7810
1763	G	A	-1.4912
1764	L	A	-0.9447
1765	E	A	-0.6073
1766	I	A	0.0000
1767	C	A	0.0000
1768	C	A	0.0000
1769	Y	A	-0.4325
1770	G	A	-0.1114
1771	P	A	-0.3605
1772	F	A	-0.5087
1773	T	A	-0.8829
1774	N	A	-1.2489
1775	M	A	0.0000
1776	P	A	-1.1447
1777	T	A	-1.2469
1778	D	A	-1.9730
1779	Q	A	-1.2498
1780	L	A	0.0000
1781	E	A	-1.2512
1782	W	A	-0.7002
1783	M	A	0.0000
1784	V	A	0.0000
1785	Q	A	-1.0076
1786	L	A	-0.7297
1787	C	A	0.0000
1788	G	A	0.0000
1789	A	A	0.0000
1790	S	A	-0.7362
1791	V	A	-0.7323
1792	V	A	0.0000
1793	K	A	-2.5214
1794	E	A	-2.6466
1795	L	A	0.0000
1796	S	A	-1.1201
1797	S	A	-0.9849
1798	F	A	-0.4639
1799	T	A	0.5389
1800	L	A	1.0441
1801	G	A	0.1588
1802	T	A	-0.1861
1803	G	A	-0.4022
1804	V	A	0.0206
1805	H	A	-0.4811
1806	P	A	-0.4374
1807	I	A	0.0000
1808	V	A	0.0000
1809	V	A	0.0000
1810	V	A	0.0000
1811	Q	A	0.0000
1812	P	A	-1.2392
1813	D	A	-1.7754
1814	A	A	-1.1030
1815	W	A	-1.4620
1816	T	A	-1.9270
1817	E	A	-2.7147
1818	D	A	-2.5633
1819	N	A	-2.3100
1820	G	A	-1.1951
1821	F	A	-0.3978
1822	H	A	-0.4469
1823	A	A	-0.2862
1824	I	A	0.0000
1825	G	A	-0.8682
1826	Q	A	-1.0483
1827	M	A	-0.3160
1828	C	A	0.0000
1829	E	A	-1.7718
1830	A	A	-1.1034
1831	P	A	-0.6233
1832	V	A	0.0000
1833	V	A	0.0000
1834	T	A	-0.4487
1835	R	A	-0.7355
1836	E	A	-1.2938
1837	W	A	0.0000
1838	V	A	0.0000
1839	L	A	0.0000
1840	D	A	-0.5428
1841	S	A	0.0000
1842	V	A	0.0000
1843	A	A	0.0000
1844	L	A	-0.7623
1845	Y	A	0.0000
1846	Q	A	-1.3514
1847	C	A	-0.9173
1848	Q	A	-1.5228
1849	E	A	-2.3091
1850	L	A	-1.2937
1851	D	A	-2.0053
1852	T	A	-1.0557
1853	Y	A	-0.6082
1854	L	A	-0.0141
1855	I	A	0.0000
1856	P	A	0.1436
1857	Q	A	0.1593
1858	I	A	1.1660
1859	P	A	0.1801