Chain sequence(s) |
A: MKINDDIKELILEYMSRYFKFENDFYKLPGIKFTDANWQKFKNGGTDIEKMGAARVNAMLDCLFDDFELAMIGKAQTNYYNDNSLKMNMPFYTYYDMFKKQQLLKWLKNNRDDVIGGTGRMYTASGNYIANAYLEVALESSSLGSGSYMLQMRFKDYSKGQEPIPSGRQNRLEWIENNLENIR B: MKINDDIKELILEYMSRYFKFENDFYKLPGIKFTDANWQKFKNGGTDIEKMGAARVNAMLDCLFDDFELAMIGKAQTNYYNDNSLKMNMPFYTYYDMFKKQQLLKWLKNNRDDVIGGTGRMYTASGNYIANAYLEVALESSSLGSGSYMLQMRFKDYSKGQEPIPSGRQNRLEWIENNLENIR |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
1 | M | A | -0.9964 | |
2 | K | A | -2.2320 | |
3 | I | A | 0.0000 | |
4 | N | A | -2.6687 | |
5 | D | A | -3.1194 | |
6 | D | A | -2.0643 | |
7 | I | A | 0.0000 | |
8 | K | A | 0.0000 | |
9 | E | A | -2.1989 | |
10 | L | A | 0.0000 | |
11 | I | A | 0.0000 | |
12 | L | A | -0.9664 | |
13 | E | A | -0.9532 | |
14 | Y | A | 0.0000 | |
15 | M | A | 0.0000 | |
16 | S | A | -0.6918 | |
17 | R | A | -0.9566 | |
18 | Y | A | 0.0000 | |
19 | F | A | 0.0000 | |
20 | K | A | -1.2135 | |
21 | F | A | 0.1665 | |
22 | E | A | -1.2905 | |
23 | N | A | -2.0094 | |
24 | D | A | -1.2923 | |
25 | F | A | 0.0000 | |
26 | Y | A | 0.0000 | |
27 | K | A | -2.7064 | |
28 | L | A | -1.2930 | |
29 | P | A | -1.2078 | |
30 | G | A | -1.4926 | |
31 | I | A | 0.0000 | |
32 | K | A | -2.5608 | |
33 | F | A | -2.1562 | |
34 | T | A | -2.3103 | |
35 | D | A | -3.1554 | |
36 | A | A | -2.2363 | |
37 | N | A | -3.0417 | |
38 | W | A | 0.0000 | |
39 | Q | A | -3.5431 | |
40 | K | A | -3.9603 | |
41 | F | A | 0.0000 | |
42 | K | A | -2.9090 | |
43 | N | A | -2.9954 | |
44 | G | A | -2.8938 | |
45 | G | A | -2.5390 | |
46 | T | A | -2.6912 | |
47 | D | A | -3.3455 | |
48 | I | A | 0.0000 | |
49 | E | A | -3.3980 | |
50 | K | A | -3.1072 | |
51 | M | A | -2.0790 | |
52 | G | A | -1.8032 | |
53 | A | A | 0.0000 | |
54 | A | A | -1.4958 | |
55 | R | A | -1.7418 | |
56 | V | A | 0.0000 | |
57 | N | A | 0.0000 | |
58 | A | A | -1.0833 | |
59 | M | A | 0.0000 | |
60 | L | A | 0.0000 | |
61 | D | A | -1.4047 | |
62 | C | A | -0.3091 | |
63 | L | A | 0.0000 | |
64 | F | A | 0.0000 | |
65 | D | A | -0.5656 | |
66 | D | A | -0.4223 | |
67 | F | A | 0.0000 | |
68 | E | A | 0.0000 | |
69 | L | A | -0.0496 | |
70 | A | A | 0.0000 | |
71 | M | A | 0.0000 | |
72 | I | A | 0.0000 | |
73 | G | A | 0.0000 | |
74 | K | A | -0.3253 | |
75 | A | A | 0.0000 | |
76 | Q | A | 0.0000 | |
77 | T | A | -1.0848 | |
78 | N | A | -1.5589 | |
79 | Y | A | 0.0000 | |
80 | Y | A | -1.3513 | |
81 | N | A | -2.6845 | |
82 | D | A | -3.0994 | |
83 | N | A | -2.7168 | |
84 | S | A | -1.4820 | |
85 | L | A | -1.2733 | |
86 | K | A | -1.5157 | |
87 | M | A | -0.4486 | |
88 | N | A | -1.0330 | |
89 | M | A | -0.2977 | |
90 | P | A | -0.4379 | |
91 | F | A | 0.0000 | |
92 | Y | A | -0.1341 | |
93 | T | A | 0.0528 | |
94 | Y | A | 0.0000 | |
95 | Y | A | 0.0000 | |
96 | D | A | -0.4085 | |
97 | M | A | 0.2489 | |
98 | F | A | 0.0310 | |
99 | K | A | 0.0000 | |
100 | K | A | -0.9545 | |
101 | Q | A | -0.9821 | |
102 | Q | A | -0.9248 | |
103 | L | A | 0.0000 | |
104 | L | A | -1.2646 | |
105 | K | A | -2.5317 | |
106 | W | A | 0.0000 | |
107 | L | A | 0.0000 | |
108 | K | A | -3.3739 | |
109 | N | A | -3.6749 | |
110 | N | A | -4.0169 | |
111 | R | A | -4.1784 | |
112 | D | A | -3.7419 | |
113 | D | A | -2.7068 | |
114 | V | A | 0.0000 | |
115 | I | A | -1.2312 | |
116 | G | A | -0.7528 | |
117 | G | A | -0.8456 | |
118 | T | A | -0.9968 | |
119 | G | A | 0.0000 | |
120 | R | A | -1.5953 | |
121 | M | A | 0.0000 | |
122 | Y | A | 0.9360 | |
123 | T | A | 0.0000 | |
124 | A | A | -0.9337 | |
125 | S | A | -0.8462 | |
126 | G | A | -0.6914 | |
127 | N | A | -0.6587 | |
128 | Y | A | 0.3581 | |
129 | I | A | -0.1896 | |
130 | A | A | -0.8009 | |
131 | N | A | -1.6151 | |
132 | A | A | 0.0000 | |
133 | Y | A | -1.0024 | |
134 | L | A | 0.0000 | |
135 | E | A | -0.8365 | |
136 | V | A | 0.0000 | |
137 | A | A | 0.0000 | |
138 | L | A | -1.2518 | |
139 | E | A | -1.7261 | |
140 | S | A | -1.2390 | |
141 | S | A | -0.6719 | |
142 | S | A | -0.6447 | |
143 | L | A | -0.3347 | |
144 | G | A | -0.7180 | |
145 | S | A | -0.7475 | |
146 | G | A | -0.6483 | |
147 | S | A | -0.5179 | |
148 | Y | A | -0.3751 | |
149 | M | A | 0.0000 | |
150 | L | A | 0.0000 | |
151 | Q | A | -0.4777 | |
152 | M | A | 0.0000 | |
153 | R | A | -0.7477 | |
154 | F | A | 0.0000 | |
155 | K | A | -1.3750 | |
156 | D | A | -1.5942 | |
157 | Y | A | -1.0463 | |
158 | S | A | -2.0097 | |
159 | K | A | -2.4876 | |
160 | G | A | -2.3865 | |
161 | Q | A | -2.7897 | |
162 | E | A | -2.8435 | |
163 | P | A | -1.3496 | |
164 | I | A | -0.7309 | |
165 | P | A | -1.2614 | |
166 | S | A | -1.2036 | |
167 | G | A | -2.0063 | |
168 | R | A | -2.8051 | |
169 | Q | A | -3.0461 | |
170 | N | A | -2.7397 | |
171 | R | A | -2.2519 | |
172 | L | A | -2.8246 | |
173 | E | A | -3.4756 | |
174 | W | A | -2.2637 | |
175 | I | A | 0.0000 | |
176 | E | A | -3.0814 | |
177 | N | A | -2.9007 | |
178 | N | A | -2.2577 | |
179 | L | A | -2.1980 | |
180 | E | A | -2.8697 | |
181 | N | A | -2.3568 | |
182 | I | A | 0.0000 | |
183 | R | A | -2.5208 | |
1 | M | B | -1.0208 | |
2 | K | B | -2.1583 | |
3 | I | B | 0.0000 | |
4 | N | B | -2.5081 | |
5 | D | B | -3.0285 | |
6 | D | B | -2.0463 | |
7 | I | B | 0.0000 | |
8 | K | B | 0.0000 | |
9 | E | B | -2.0023 | |
10 | L | B | 0.0000 | |
11 | I | B | 0.0000 | |
12 | L | B | -0.6307 | |
13 | E | B | -0.6736 | |
14 | Y | B | 0.0000 | |
15 | M | B | 0.0000 | |
16 | S | B | -0.5168 | |
17 | R | B | -0.8749 | |
18 | Y | B | 0.0000 | |
19 | F | B | 0.0000 | |
20 | K | B | -1.1402 | |
21 | F | B | 0.3028 | |
22 | E | B | -1.0030 | |
23 | N | B | -1.9737 | |
24 | D | B | -1.2800 | |
25 | F | B | 0.0000 | |
26 | Y | B | 0.0000 | |
27 | K | B | -2.8388 | |
28 | L | B | 0.0000 | |
29 | P | B | -1.2906 | |
30 | G | B | -1.5628 | |
31 | I | B | 0.0000 | |
32 | K | B | -2.6185 | |
33 | F | B | -2.0716 | |
34 | T | B | -2.1475 | |
35 | D | B | -3.0103 | |
36 | A | B | -1.9656 | |
37 | N | B | -2.3112 | |
38 | W | B | 0.0000 | |
39 | Q | B | -3.2676 | |
40 | K | B | -3.6683 | |
41 | F | B | 0.0000 | |
42 | K | B | -2.5413 | |
43 | N | B | -2.7235 | |
44 | G | B | -2.8187 | |
45 | G | B | -2.4195 | |
46 | T | B | -2.4818 | |
47 | D | B | -3.2043 | |
48 | I | B | 0.0000 | |
49 | E | B | -2.8801 | |
50 | K | B | -2.8710 | |
51 | M | B | -1.8403 | |
52 | G | B | -1.8590 | |
53 | A | B | 0.0000 | |
54 | A | B | -1.7651 | |
55 | R | B | -1.7553 | |
56 | V | B | 0.0000 | |
57 | N | B | -1.0198 | |
58 | A | B | -1.0926 | |
59 | M | B | 0.0000 | |
60 | L | B | 0.0000 | |
61 | D | B | -1.2217 | |
62 | C | B | -0.2732 | |
63 | L | B | 0.0000 | |
64 | F | B | 0.0000 | |
65 | D | B | -0.3592 | |
66 | D | B | 0.0000 | |
67 | F | B | 0.0000 | |
68 | E | B | 0.0000 | |
69 | L | B | 0.0420 | |
70 | A | B | 0.0000 | |
71 | M | B | 0.0000 | |
72 | I | B | 0.0000 | |
73 | G | B | 0.0000 | |
74 | K | B | -0.4595 | |
75 | A | B | 0.0000 | |
76 | Q | B | 0.0000 | |
77 | T | B | -1.0862 | |
78 | N | B | -1.9290 | |
79 | Y | B | 0.0000 | |
80 | Y | B | -1.5751 | |
81 | N | B | -2.8720 | |
82 | D | B | -3.2459 | |
83 | N | B | -2.7554 | |
84 | S | B | -1.7028 | |
85 | L | B | -1.5971 | |
86 | K | B | -1.7454 | |
87 | M | B | -0.5480 | |
88 | N | B | -1.1521 | |
89 | M | B | -0.3503 | |
90 | P | B | -0.4553 | |
91 | F | B | 0.0000 | |
92 | Y | B | -0.0372 | |
93 | T | B | 0.0980 | |
94 | Y | B | 0.2090 | |
95 | Y | B | 0.0000 | |
96 | D | B | -0.3889 | |
97 | M | B | 0.1041 | |
98 | F | B | -0.0320 | |
99 | K | B | 0.0000 | |
100 | K | B | -1.2689 | |
101 | Q | B | -1.0785 | |
102 | Q | B | -0.9549 | |
103 | L | B | 0.0000 | |
104 | L | B | -1.4361 | |
105 | K | B | -2.5309 | |
106 | W | B | 0.0000 | |
107 | L | B | 0.0000 | |
108 | K | B | -3.6149 | |
109 | N | B | -3.6717 | |
110 | N | B | -4.0583 | |
111 | R | B | -4.2755 | |
112 | D | B | -3.7570 | |
113 | D | B | -2.7562 | |
114 | V | B | 0.0000 | |
115 | I | B | -1.3586 | |
116 | G | B | -0.7895 | |
117 | G | B | -0.8994 | |
118 | T | B | -1.0201 | |
119 | G | B | 0.0000 | |
120 | R | B | -1.5022 | |
121 | M | B | 0.0000 | |
122 | Y | B | 1.0970 | |
123 | T | B | 0.0000 | |
124 | A | B | -0.9673 | |
125 | S | B | -0.8229 | |
126 | G | B | -0.6435 | |
127 | N | B | -0.5017 | |
128 | Y | B | 0.7209 | |
129 | I | B | -0.0434 | |
130 | A | B | -0.7173 | |
131 | N | B | -1.6170 | |
132 | A | B | 0.0000 | |
133 | Y | B | -1.0809 | |
134 | L | B | 0.0000 | |
135 | E | B | -0.6714 | |
136 | V | B | 0.0000 | |
137 | A | B | 0.0000 | |
138 | L | B | -1.1178 | |
139 | E | B | -1.4717 | |
140 | S | B | -1.1511 | |
141 | S | B | -0.6696 | |
142 | S | B | -0.4327 | |
143 | L | B | -0.4131 | |
144 | G | B | -0.5530 | |
145 | S | B | -0.5111 | |
146 | G | B | -0.6033 | |
147 | S | B | -0.4610 | |
148 | Y | B | -0.1052 | |
149 | M | B | 0.0000 | |
150 | L | B | 0.0000 | |
151 | Q | B | 0.0000 | |
152 | M | B | 0.0000 | |
153 | R | B | -0.6721 | |
154 | F | B | 0.0000 | |
155 | K | B | -1.4515 | |
156 | D | B | -1.7580 | |
157 | Y | B | -1.1993 | |
158 | S | B | -2.0805 | |
159 | K | B | -2.4980 | |
160 | G | B | -2.3910 | |
161 | Q | B | -2.7908 | |
162 | E | B | -2.8415 | |
163 | P | B | -1.6479 | |
164 | I | B | -0.8199 | |
165 | P | B | -1.3750 | |
166 | S | B | -1.4052 | |
167 | G | B | -2.2197 | |
168 | R | B | -3.4081 | |
169 | Q | B | -3.3181 | |
170 | N | B | -3.2552 | |
171 | R | B | -2.7249 | |
172 | L | B | -3.0421 | |
173 | E | B | -3.6120 | |
174 | W | B | -2.3598 | |
175 | I | B | 0.0000 | |
176 | E | B | -2.8273 | |
177 | N | B | -2.7992 | |
178 | N | B | -2.1882 | |
179 | L | B | -2.1332 | |
180 | E | B | -2.8226 | |
181 | N | B | -2.3164 | |
182 | I | B | 0.0000 | |
183 | R | B | -2.5526 |