Project name: 8f047139587eaf1 [mutate: FB19D, WB23D]
Status: done
submitted: 2018-04-17 07:14:35, status changed: 2018-04-17 17:23:13
Settings
Chain sequence(s)
|
B: LSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGP
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Mutated residues
|
FB19D, WB23D
|
Energy difference between WT (input) and mutated protein (by FoldX)
|
0.654785 kcal/mol
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.3639
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Maximal score value
-
1.8919
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Average score
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-0.9431
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Total score value
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-44.3263
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
14 |
L |
B |
0.8202 |
|
15 |
S |
B |
-0.6768 |
|
16 |
Q |
B |
-2.2372 |
|
17 |
E |
B |
-2.8039 |
|
18 |
T |
B |
-2.5808 |
|
19 |
D |
B |
-3.3450 |
mutated: FB19D
|
20 |
S |
B |
-2.6825 |
|
21 |
D |
B |
-3.0214 |
|
22 |
L |
B |
-1.1147 |
|
23 |
D |
B |
-1.8825 |
mutated: WB23D
|
24 |
K |
B |
-1.9755 |
|
25 |
L |
B |
0.5867 |
|
26 |
L |
B |
0.5367 |
|
27 |
P |
B |
-0.5542 |
|
28 |
E |
B |
-1.9145 |
|
29 |
N |
B |
-1.7346 |
|
30 |
N |
B |
-1.3614 |
|
31 |
V |
B |
0.8476 |
|
32 |
L |
B |
1.5765 |
|
33 |
S |
B |
0.7897 |
|
34 |
P |
B |
1.0768 |
|
35 |
L |
B |
1.8919 |
|
36 |
P |
B |
0.3060 |
|
37 |
S |
B |
-0.2263 |
|
38 |
Q |
B |
-1.1445 |
|
39 |
A |
B |
-0.5694 |
|
40 |
M |
B |
0.3266 |
|
41 |
D |
B |
-1.2005 |
|
42 |
D |
B |
-0.5692 |
|
43 |
L |
B |
0.9048 |
|
44 |
M |
B |
1.4231 |
|
45 |
L |
B |
0.3833 |
|
46 |
S |
B |
-0.9099 |
|
47 |
P |
B |
-2.1586 |
|
48 |
D |
B |
-3.3639 |
|
49 |
D |
B |
-3.0110 |
|
50 |
I |
B |
0.0000 |
|
51 |
E |
B |
-2.8148 |
|
52 |
Q |
B |
-2.2713 |
|
53 |
W |
B |
0.0556 |
|
54 |
F |
B |
0.7776 |
|
55 |
T |
B |
-0.9023 |
|
56 |
E |
B |
-2.6758 |
|
57 |
D |
B |
-2.9949 |
|
58 |
P |
B |
-1.7268 |
|
59 |
G |
B |
-1.3968 |
|
60 |
P |
B |
-0.8084 |
|