Project name: 4hix:L
Status: done
submitted: 2019-03-21 14:48:04, status changed: 2019-03-21 14:57:38
Settings
Chain sequence(s)
|
L: YVVMTQSPLSLPVTPGEPASISCKSSQSLLDSDGKTYLNWLLQKPGQSPQRLIYLVSKLDSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCWQGTHFPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4709
-
Maximal score value
-
1.6879
-
Average score
-
-0.8299
-
Total score value
-
-181.75
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
Y |
L |
1.6879 |
|
2 |
V |
L |
0.0000 |
|
3 |
V |
L |
1.5498 |
|
4 |
M |
L |
0.0000 |
|
5 |
T |
L |
-0.2980 |
|
6 |
Q |
L |
0.0000 |
|
7 |
S |
L |
-0.1274 |
|
8 |
P |
L |
0.3195 |
|
9 |
L |
L |
0.8885 |
|
10 |
S |
L |
0.1548 |
|
11 |
L |
L |
-0.1406 |
|
12 |
P |
L |
-0.7541 |
|
13 |
V |
L |
0.0000 |
|
14 |
T |
L |
-1.6923 |
|
15 |
P |
L |
-1.9542 |
|
16 |
G |
L |
-2.0228 |
|
17 |
E |
L |
-2.5752 |
|
18 |
P |
L |
-2.1800 |
|
19 |
A |
L |
0.0000 |
|
20 |
S |
L |
-0.6878 |
|
21 |
I |
L |
0.0000 |
|
22 |
S |
L |
-0.8722 |
|
23 |
C |
L |
0.0000 |
|
24 |
K |
L |
-2.0778 |
|
25 |
S |
L |
0.0000 |
|
26 |
S |
L |
-0.3235 |
|
27 |
Q |
L |
-0.6073 |
|
27A |
S |
L |
-0.6059 |
|
27B |
L |
L |
0.0000 |
|
27C |
L |
L |
0.2421 |
|
27D |
D |
L |
-1.2182 |
|
27E |
S |
L |
-1.4323 |
|
28 |
D |
L |
-2.4876 |
|
29 |
G |
L |
-1.8453 |
|
30 |
K |
L |
-1.7838 |
|
31 |
T |
L |
-0.4970 |
|
32 |
Y |
L |
0.0315 |
|
33 |
L |
L |
0.0000 |
|
34 |
N |
L |
-0.0987 |
|
35 |
W |
L |
0.0000 |
|
36 |
L |
L |
0.0000 |
|
37 |
L |
L |
0.0000 |
|
38 |
Q |
L |
-1.4239 |
|
39 |
K |
L |
-1.7257 |
|
40 |
P |
L |
-1.2819 |
|
41 |
G |
L |
-1.3920 |
|
42 |
Q |
L |
-1.9465 |
|
43 |
S |
L |
-1.5517 |
|
44 |
P |
L |
-1.6045 |
|
45 |
Q |
L |
-2.2198 |
|
46 |
R |
L |
-1.8315 |
|
47 |
L |
L |
0.0000 |
|
48 |
I |
L |
0.0000 |
|
49 |
Y |
L |
-0.1178 |
|
50 |
L |
L |
-0.0882 |
|
51 |
V |
L |
-0.2346 |
|
52 |
S |
L |
-0.7017 |
|
53 |
K |
L |
-1.2899 |
|
54 |
L |
L |
-1.0406 |
|
55 |
D |
L |
-1.0592 |
|
56 |
S |
L |
-0.8371 |
|
57 |
G |
L |
-0.9409 |
|
58 |
V |
L |
0.0000 |
|
59 |
P |
L |
-1.2114 |
|
60 |
D |
L |
-2.0454 |
|
61 |
R |
L |
-2.1347 |
|
62 |
F |
L |
0.0000 |
|
63 |
S |
L |
-1.2449 |
|
64 |
G |
L |
0.0000 |
|
65 |
S |
L |
-0.8161 |
|
66 |
G |
L |
-1.1292 |
|
67 |
S |
L |
-0.7722 |
|
68 |
G |
L |
-0.7604 |
|
69 |
T |
L |
-1.5418 |
|
70 |
D |
L |
-2.6325 |
|
71 |
F |
L |
0.0000 |
|
72 |
T |
L |
-1.0466 |
|
73 |
L |
L |
0.0000 |
|
74 |
K |
L |
-1.4702 |
|
75 |
I |
L |
0.0000 |
|
76 |
S |
L |
-2.3497 |
|
77 |
R |
L |
-3.1463 |
|
78 |
V |
L |
0.0000 |
|
79 |
E |
L |
-2.7023 |
|
80 |
A |
L |
-2.4137 |
|
81 |
E |
L |
-2.6562 |
|
82 |
D |
L |
0.0000 |
|
83 |
V |
L |
0.0000 |
|
84 |
G |
L |
0.0000 |
|
85 |
V |
L |
-0.2715 |
|
86 |
Y |
L |
0.0000 |
|
87 |
Y |
L |
-0.0876 |
|
88 |
C |
L |
0.0000 |
|
89 |
W |
L |
0.0000 |
|
90 |
Q |
L |
0.0000 |
|
91 |
G |
L |
-0.5208 |
|
92 |
T |
L |
-0.5246 |
|
93 |
H |
L |
0.2870 |
|
94 |
F |
L |
1.2572 |
|
95 |
P |
L |
0.2474 |
|
96 |
R |
L |
-0.9432 |
|
97 |
T |
L |
0.1846 |
|
98 |
F |
L |
0.5406 |
|
99 |
G |
L |
0.0000 |
|
100 |
Q |
L |
-0.5483 |
|
101 |
G |
L |
0.0000 |
|
102 |
T |
L |
0.0000 |
|
103 |
K |
L |
-0.6815 |
|
104 |
V |
L |
0.0000 |
|
105 |
E |
L |
-1.1626 |
|
106 |
I |
L |
0.0000 |
|
107 |
K |
L |
-1.5088 |
|
108 |
R |
L |
-1.1493 |
|
109 |
T |
L |
-0.2142 |
|
110 |
V |
L |
0.1078 |
|
111 |
A |
L |
-0.2318 |
|
112 |
A |
L |
-0.2701 |
|
113 |
P |
L |
0.0000 |
|
114 |
S |
L |
-0.1266 |
|
115 |
V |
L |
0.0000 |
|
116 |
F |
L |
1.1103 |
|
117 |
I |
L |
1.1162 |
|
118 |
F |
L |
1.4284 |
|
119 |
P |
L |
-0.0137 |
|
120 |
P |
L |
0.0000 |
|
121 |
S |
L |
-1.7469 |
|
122 |
D |
L |
-3.2447 |
|
123 |
E |
L |
-3.4709 |
|
124 |
Q |
L |
-2.5297 |
|
125 |
L |
L |
-2.4477 |
|
126 |
K |
L |
-3.1316 |
|
127 |
S |
L |
-2.0169 |
|
128 |
G |
L |
-1.5994 |
|
129 |
T |
L |
-1.3638 |
|
130 |
A |
L |
0.0000 |
|
131 |
S |
L |
0.0425 |
|
132 |
V |
L |
0.0000 |
|
133 |
V |
L |
0.6715 |
|
134 |
C |
L |
0.0000 |
|
135 |
L |
L |
0.4530 |
|
136 |
L |
L |
0.0000 |
|
137 |
N |
L |
-0.6740 |
|
138 |
N |
L |
-1.3467 |
|
139 |
F |
L |
0.0000 |
|
140 |
Y |
L |
0.0000 |
|
141 |
P |
L |
-1.7803 |
|
142 |
R |
L |
-2.9093 |
|
143 |
E |
L |
-3.2206 |
|
144 |
A |
L |
-2.3349 |
|
145 |
K |
L |
-2.5062 |
|
146 |
V |
L |
-1.1698 |
|
147 |
Q |
L |
-0.8575 |
|
148 |
W |
L |
0.0000 |
|
149 |
K |
L |
-0.8681 |
|
150 |
V |
L |
0.0000 |
|
151 |
D |
L |
-2.0639 |
|
152 |
N |
L |
-1.4712 |
|
153 |
A |
L |
-0.4562 |
|
154 |
L |
L |
0.3414 |
|
155 |
Q |
L |
-0.3238 |
|
156 |
S |
L |
-0.5064 |
|
157 |
G |
L |
-0.9866 |
|
158 |
N |
L |
-0.9283 |
|
159 |
S |
L |
-1.4493 |
|
160 |
Q |
L |
-2.3053 |
|
161 |
E |
L |
-2.3580 |
|
162 |
S |
L |
-1.2671 |
|
163 |
V |
L |
-0.5401 |
|
164 |
T |
L |
-0.8118 |
|
165 |
E |
L |
-1.3059 |
|
166 |
Q |
L |
0.0000 |
|
167 |
D |
L |
-2.2944 |
|
168 |
S |
L |
-2.3750 |
|
169 |
K |
L |
-2.8733 |
|
170 |
D |
L |
-2.1870 |
|
171 |
S |
L |
0.0000 |
|
172 |
T |
L |
0.0000 |
|
173 |
Y |
L |
0.0000 |
|
174 |
S |
L |
-0.8510 |
|
175 |
L |
L |
0.0000 |
|
176 |
S |
L |
-0.5381 |
|
177 |
S |
L |
0.0000 |
|
178 |
T |
L |
-0.6701 |
|
179 |
L |
L |
0.0000 |
|
180 |
T |
L |
-0.4584 |
|
181 |
L |
L |
-0.5751 |
|
182 |
S |
L |
-0.9196 |
|
183 |
K |
L |
-1.9304 |
|
184 |
A |
L |
-1.6345 |
|
185 |
D |
L |
-2.0945 |
|
186 |
Y |
L |
0.0000 |
|
187 |
E |
L |
-3.0176 |
|
188 |
K |
L |
-3.2939 |
|
189 |
H |
L |
-2.9577 |
|
190 |
K |
L |
-3.0157 |
|
191 |
V |
L |
-1.6882 |
|
192 |
Y |
L |
0.0000 |
|
193 |
A |
L |
0.0000 |
|
194 |
C |
L |
0.0000 |
|
195 |
E |
L |
-1.0464 |
|
196 |
V |
L |
0.0000 |
|
197 |
T |
L |
-1.2563 |
|
198 |
H |
L |
0.0000 |
|
199 |
Q |
L |
-1.7965 |
|
200 |
G |
L |
-0.4866 |
|
201 |
L |
L |
-0.2767 |
|
202 |
S |
L |
-0.4343 |
|
203 |
S |
L |
-0.4334 |
|
204 |
P |
L |
-0.5595 |
|
205 |
V |
L |
-0.0288 |
|
206 |
T |
L |
-0.4947 |
|
207 |
K |
L |
-0.5063 |
|
208 |
S |
L |
-0.4773 |
|
209 |
F |
L |
-0.8995 |
|
210 |
N |
L |
-2.2445 |
|
211 |
R |
L |
-2.5167 |
|
212 |
G |
L |
-2.1279 |
|
213 |
E |
L |
-2.1555 |
|
214 |
C |
L |
-1.4060 |
|