Project name: 6arp:A
Status: done
submitted: 2019-03-21 14:52:42, status changed: 2019-03-21 15:02:32
Settings
Chain sequence(s)
|
A: DILLTQSPVILSSVSPGERVSSFSSCRASQSIGTNIHWYQQRTNGSPRLLIKYADESSIDGIPSRFSGSGSSGTDFTLSINSVESEDIIADYYCQQNNNNWPTTFGAGTKLELKRTVAAPSSVFIFPPSDEQLKSGTASVVCLLNNNFYPREAKVQWKVDNNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEEKHKVYACCEVTTHQGLSSPVTKSFNRGE
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5718
-
Maximal score value
-
1.8679
-
Average score
-
-0.8935
-
Total score value
-
-190.3098
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
A |
-1.4670 |
|
2 |
I |
A |
0.0000 |
|
3 |
L |
A |
0.9137 |
|
4 |
L |
A |
0.0000 |
|
5 |
T |
A |
0.0474 |
|
6 |
Q |
A |
0.2305 |
|
7 |
S |
A |
0.3077 |
|
8 |
P |
A |
0.8670 |
|
9 |
V |
A |
1.8679 |
|
10 |
I |
A |
1.4530 |
|
11 |
L |
A |
0.6249 |
|
12 |
S |
A |
-0.0386 |
|
13 |
V |
A |
-0.8755 |
|
14 |
S |
A |
-1.6187 |
|
15 |
P |
A |
-1.9190 |
|
16 |
G |
A |
-2.1285 |
|
17 |
E |
A |
-2.9596 |
|
18 |
R |
A |
-3.2687 |
|
19 |
V |
A |
0.0000 |
|
20 |
S |
A |
-0.9857 |
|
21 |
F |
A |
0.0000 |
|
22 |
S |
A |
-0.5994 |
|
23 |
C |
A |
0.0000 |
|
24 |
R |
A |
-1.7057 |
|
25 |
A |
A |
0.0000 |
|
26 |
S |
A |
-0.9419 |
|
27 |
Q |
A |
-1.8134 |
|
28 |
S |
A |
-1.5584 |
|
29 |
I |
A |
0.0000 |
|
30 |
G |
A |
-1.0240 |
|
31 |
T |
A |
-0.9292 |
|
32 |
N |
A |
-1.1156 |
|
33 |
I |
A |
0.0000 |
|
34 |
H |
A |
-0.4998 |
|
35 |
W |
A |
0.0000 |
|
36 |
Y |
A |
-0.1552 |
|
37 |
Q |
A |
0.0000 |
|
38 |
Q |
A |
-1.4274 |
|
39 |
R |
A |
-1.9850 |
|
40 |
T |
A |
-1.7194 |
|
41 |
N |
A |
-1.8563 |
|
42 |
G |
A |
-1.3973 |
|
43 |
S |
A |
-1.0138 |
|
44 |
P |
A |
-0.9891 |
|
45 |
R |
A |
-0.7494 |
|
46 |
L |
A |
-0.3082 |
|
47 |
L |
A |
0.0000 |
|
48 |
I |
A |
0.0000 |
|
49 |
K |
A |
-1.2346 |
|
50 |
Y |
A |
-0.5215 |
|
51 |
A |
A |
0.0000 |
|
52 |
D |
A |
-2.7353 |
|
53 |
E |
A |
-2.6995 |
|
54 |
S |
A |
-1.8446 |
|
55 |
I |
A |
-1.4207 |
|
56 |
D |
A |
-1.8150 |
|
57 |
G |
A |
-1.1582 |
|
58 |
I |
A |
-0.6217 |
|
59 |
P |
A |
-0.5223 |
|
60 |
S |
A |
-0.7864 |
|
61 |
R |
A |
-1.2666 |
|
62 |
F |
A |
0.0000 |
|
63 |
S |
A |
-1.4528 |
|
64 |
G |
A |
-1.3982 |
|
65 |
S |
A |
-1.3298 |
|
66 |
G |
A |
-1.2418 |
|
67 |
S |
A |
-1.0299 |
|
68 |
G |
A |
-1.2610 |
|
69 |
T |
A |
-1.7927 |
|
70 |
D |
A |
-2.5357 |
|
71 |
F |
A |
0.0000 |
|
72 |
T |
A |
-1.0298 |
|
73 |
L |
A |
0.0000 |
|
74 |
S |
A |
-1.0403 |
|
75 |
I |
A |
0.0000 |
|
76 |
N |
A |
-2.8051 |
|
77 |
S |
A |
-2.4431 |
|
78 |
V |
A |
0.0000 |
|
79 |
E |
A |
-2.2661 |
|
80 |
S |
A |
-2.2642 |
|
81 |
E |
A |
-2.3213 |
|
82 |
D |
A |
0.0000 |
|
83 |
I |
A |
-1.5705 |
|
84 |
A |
A |
0.0000 |
|
85 |
D |
A |
-1.0335 |
|
86 |
Y |
A |
0.0000 |
|
87 |
Y |
A |
0.0760 |
|
88 |
C |
A |
0.0000 |
|
89 |
Q |
A |
0.2978 |
|
90 |
Q |
A |
0.0000 |
|
91 |
N |
A |
-1.6193 |
|
92 |
N |
A |
-2.1569 |
|
93 |
N |
A |
-1.6700 |
|
94 |
W |
A |
-0.1400 |
|
95 |
P |
A |
-0.2652 |
|
96 |
T |
A |
-0.5839 |
|
97 |
T |
A |
0.2845 |
|
98 |
F |
A |
1.4899 |
|
99 |
G |
A |
0.8127 |
|
100 |
A |
A |
0.5562 |
|
101 |
G |
A |
0.2396 |
|
102 |
T |
A |
0.0000 |
|
103 |
K |
A |
-0.7721 |
|
104 |
L |
A |
0.0000 |
|
105 |
E |
A |
-0.7902 |
|
106 |
L |
A |
0.0000 |
|
107 |
K |
A |
-1.4505 |
|
108 |
R |
A |
-1.0847 |
|
109 |
T |
A |
-0.1621 |
|
110 |
V |
A |
0.1646 |
|
111 |
A |
A |
-0.2052 |
|
112 |
A |
A |
-0.2737 |
|
113 |
P |
A |
0.0000 |
|
114 |
S |
A |
-0.0910 |
|
115 |
V |
A |
0.0000 |
|
116 |
F |
A |
1.3863 |
|
117 |
I |
A |
1.2409 |
|
118 |
F |
A |
1.4292 |
|
119 |
P |
A |
0.0087 |
|
120 |
P |
A |
-0.7228 |
|
121 |
S |
A |
-1.8284 |
|
122 |
D |
A |
-3.2199 |
|
123 |
E |
A |
-3.4040 |
|
124 |
Q |
A |
-2.4731 |
|
125 |
L |
A |
-2.5329 |
|
126 |
K |
A |
-2.9925 |
|
127 |
S |
A |
-1.8712 |
|
128 |
G |
A |
-1.3230 |
|
129 |
T |
A |
-1.1622 |
|
130 |
A |
A |
0.0000 |
|
131 |
S |
A |
0.0209 |
|
132 |
V |
A |
0.0000 |
|
133 |
V |
A |
0.6680 |
|
134 |
C |
A |
0.0000 |
|
135 |
L |
A |
0.5498 |
|
136 |
L |
A |
0.0000 |
|
137 |
N |
A |
-0.5287 |
|
138 |
N |
A |
-1.2437 |
|
139 |
F |
A |
0.0000 |
|
140 |
Y |
A |
0.0000 |
|
141 |
P |
A |
-1.7707 |
|
142 |
R |
A |
-3.0544 |
|
143 |
E |
A |
-3.1294 |
|
144 |
A |
A |
-2.1651 |
|
145 |
K |
A |
-2.0740 |
|
146 |
V |
A |
-0.9530 |
|
147 |
Q |
A |
-0.7063 |
|
148 |
W |
A |
0.0000 |
|
149 |
K |
A |
-0.7560 |
|
150 |
V |
A |
0.0000 |
|
151 |
D |
A |
-1.8670 |
|
152 |
N |
A |
-1.5771 |
|
153 |
A |
A |
-0.4280 |
|
154 |
L |
A |
0.3077 |
|
155 |
Q |
A |
-0.5316 |
|
156 |
S |
A |
-0.7538 |
|
157 |
G |
A |
-1.4068 |
|
158 |
N |
A |
-1.7921 |
|
159 |
S |
A |
-1.8746 |
|
160 |
Q |
A |
-2.5048 |
|
161 |
E |
A |
-2.4006 |
|
162 |
S |
A |
-1.4408 |
|
163 |
V |
A |
-1.0795 |
|
164 |
T |
A |
-1.2396 |
|
165 |
E |
A |
-2.3129 |
|
166 |
Q |
A |
0.0000 |
|
167 |
D |
A |
-2.3337 |
|
168 |
S |
A |
-2.4837 |
|
169 |
K |
A |
-2.8124 |
|
170 |
D |
A |
-2.1339 |
|
171 |
S |
A |
0.0000 |
|
172 |
T |
A |
0.0000 |
|
173 |
Y |
A |
-1.5730 |
|
174 |
S |
A |
-0.9780 |
|
175 |
L |
A |
0.0000 |
|
176 |
S |
A |
-0.5442 |
|
177 |
S |
A |
0.0000 |
|
178 |
T |
A |
-0.7962 |
|
179 |
L |
A |
0.0000 |
|
180 |
T |
A |
-0.7618 |
|
181 |
L |
A |
-0.8784 |
|
182 |
S |
A |
-1.0883 |
|
183 |
K |
A |
-2.1252 |
|
184 |
A |
A |
-1.8999 |
|
185 |
D |
A |
-2.6184 |
|
186 |
Y |
A |
0.0000 |
|
187 |
E |
A |
-3.3675 |
|
188 |
K |
A |
-3.5718 |
|
189 |
H |
A |
-2.8936 |
|
190 |
K |
A |
-3.0088 |
|
191 |
V |
A |
-1.2204 |
|
192 |
Y |
A |
0.0000 |
|
193 |
A |
A |
0.0000 |
|
194 |
C |
A |
0.0000 |
|
195 |
E |
A |
-0.8230 |
|
196 |
V |
A |
0.0000 |
|
197 |
T |
A |
-1.0737 |
|
198 |
H |
A |
0.0000 |
|
199 |
Q |
A |
-1.7527 |
|
200 |
G |
A |
-0.4991 |
|
201 |
L |
A |
-0.2872 |
|
202 |
S |
A |
-0.4727 |
|
203 |
S |
A |
-0.4295 |
|
204 |
P |
A |
-0.4833 |
|
205 |
V |
A |
-0.0210 |
|
206 |
T |
A |
-0.3384 |
|
207 |
K |
A |
-0.2235 |
|
208 |
S |
A |
-0.2169 |
|
209 |
F |
A |
-0.6949 |
|
210 |
N |
A |
-1.8054 |
|
211 |
R |
A |
-2.4798 |
|
212 |
G |
A |
-2.0996 |
|
213 |
E |
A |
-2.4875 |
|