Project name: 5%_pg_2osl

Chain sequence(s)	A: QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.7616
• Maximal score value: 1.9212
• Average score: -0.6087
• Total score value: -264.7985

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.1264
2	I	A	0.0000
3	V	A	1.0024
4	L	A	0.0000
5	S	A	-0.6934
6	Q	A	-0.7633
7	S	A	-0.3236
8	P	A	0.3901
9	A	A	0.7260
10	I	A	1.9212
11	L	A	0.9988
12	S	A	0.0290
13	A	A	0.0000
14	S	A	-1.7538
15	P	A	-2.1411
16	G	A	-2.2876
17	E	A	-2.8075
18	K	A	-2.9428
19	V	A	0.0000
20	T	A	-0.4384
21	M	A	0.0000
22	T	A	-0.6830
23	C	A	0.0000
24	R	A	-1.9544
25	A	A	-0.7510
26	S	A	-0.4096
27	S	A	-0.5300
28	S	A	-0.7030
29	V	A	0.0000
30	S	A	-0.1756
31	Y	A	0.2524
32	I	A	0.0000
33	H	A	0.0000
34	W	A	0.0000
35	F	A	0.0000
36	Q	A	0.0000
37	Q	A	-0.6143
38	K	A	0.0000
39	P	A	-0.6966
40	G	A	-0.5805
41	S	A	-0.5870
42	S	A	-0.4474
43	P	A	0.0000
44	K	A	-1.3458
45	P	A	-0.6094
46	W	A	-0.3993
47	I	A	0.0000
48	Y	A	0.0213
49	A	A	-0.2054
50	T	A	-0.2852
51	S	A	-0.6276
52	N	A	-0.9757
53	L	A	0.0774
54	A	A	-0.4149
55	S	A	-0.4965
56	G	A	-0.1974
57	V	A	0.0000
58	P	A	0.6757
59	V	A	1.4076
60	R	A	-0.2982
61	F	A	0.0000
62	S	A	-0.0985
63	G	A	0.0000
64	S	A	-0.5733
65	G	A	-0.7259
66	S	A	-0.6978
67	G	A	-0.6934
68	T	A	-1.0121
69	S	A	-1.2807
70	Y	A	0.0000
71	S	A	-0.6043
72	L	A	0.0000
73	T	A	-0.7451
74	I	A	0.0000
75	S	A	-2.0055
76	R	A	-3.0318
77	V	A	0.0000
78	E	A	-2.7115
79	A	A	0.0000
80	E	A	-2.9388
81	D	A	0.0000
82	A	A	0.0000
83	A	A	0.0000
84	T	A	0.0266
85	Y	A	0.0000
86	Y	A	-0.0734
87	C	A	0.0000
88	Q	A	0.0000
89	Q	A	0.0000
90	W	A	-0.1215
91	T	A	-0.3011
92	S	A	-1.0223
93	N	A	-1.5784
94	P	A	-1.4355
95	P	A	0.0000
96	T	A	0.0000
97	F	A	0.3032
98	G	A	0.0000
99	G	A	-0.6264
100	G	A	-0.1638
101	T	A	0.0000
102	K	A	0.3510
103	L	A	0.0000
104	E	A	-0.5512
105	I	A	0.0000
106	K	A	-1.1710
107	R	A	-0.7215
108	T	A	0.3073
109	V	A	1.2475
110	A	A	0.4294
111	A	A	0.0014
112	P	A	0.0000
113	S	A	-0.1924
114	V	A	0.0000
115	F	A	0.1091
116	I	A	0.0000
117	F	A	0.0000
118	P	A	-0.4442
119	P	A	0.0000
120	S	A	-1.1601
121	D	A	-2.3140
122	E	A	-1.7934
123	Q	A	0.0000
124	L	A	-1.2798
125	K	A	-1.5551
126	S	A	-1.0856
127	G	A	-0.8143
128	T	A	-0.9346
129	A	A	0.0000
130	S	A	0.0000
131	V	A	0.0000
132	V	A	0.0000
133	C	A	0.0000
134	L	A	0.0000
135	L	A	0.0000
136	N	A	0.0000
137	N	A	-0.9071
138	F	A	0.0000
139	Y	A	0.0000
140	P	A	0.0000
141	R	A	-3.0071
142	E	A	-3.2892
143	A	A	-2.5132
144	K	A	-2.5595
145	V	A	0.0000
146	Q	A	-1.0867
147	W	A	0.0000
148	K	A	-0.9355
149	V	A	0.0000
150	D	A	-2.5515
151	N	A	-1.9133
152	A	A	-0.6030
153	L	A	0.1245
154	Q	A	-0.6359
155	S	A	-0.8735
156	G	A	-1.2975
157	N	A	-1.4383
158	S	A	-1.1667
159	Q	A	-1.8194
160	E	A	-1.8210
161	S	A	-0.8390
162	V	A	-0.6131
163	T	A	-0.7899
164	E	A	-1.1626
165	Q	A	0.0000
166	D	A	-2.1595
167	S	A	-2.5613
168	K	A	-2.8917
169	D	A	-2.1250
170	S	A	0.0000
171	T	A	0.0000
172	Y	A	0.0000
173	S	A	0.0000
174	L	A	0.0000
175	S	A	0.0000
176	S	A	0.0000
177	T	A	-0.2005
178	L	A	0.6069
179	T	A	0.1949
180	L	A	-0.2665
181	S	A	-1.1840
182	K	A	-2.0146
183	A	A	-1.8429
184	D	A	-2.6027
185	Y	A	0.0000
186	E	A	-3.7616
187	K	A	-3.7235
188	H	A	-3.3425
189	K	A	-3.6109
190	V	A	0.0000
191	Y	A	0.0000
192	A	A	0.0000
193	C	A	0.0000
194	E	A	-0.9494
195	V	A	0.0000
196	T	A	-1.3269
197	H	A	0.0000
198	Q	A	-1.4492
199	G	A	-0.1791
200	L	A	-0.1321
201	S	A	-0.4376
202	S	A	-0.4493
203	P	A	-0.6300
204	V	A	-0.0129
205	T	A	-0.3526
206	K	A	-0.3804
207	S	A	-0.4883
208	F	A	-1.0735
209	N	A	-2.2093
210	R	A	-2.6106
211	G	A	-2.3349
212	E	A	-2.5356
1	Q	A	-0.9992
2	V	A	0.0255
3	Q	A	-0.9565
4	L	A	0.0000
5	Q	A	-1.9305
6	Q	A	-1.2263
7	P	A	-0.9026
8	G	A	-0.7868
9	A	A	-0.7329
10	E	A	-0.8803
11	L	A	-0.3049
12	V	A	0.0000
13	K	A	-1.9023
14	P	A	-1.3622
15	G	A	-1.2015
16	A	A	-0.9755
17	S	A	-1.0782
18	V	A	-1.1496
19	K	A	-1.9466
20	M	A	0.0000
21	S	A	-0.9583
22	C	A	0.0000
23	K	A	-1.8566
24	A	A	0.0000
25	S	A	-0.9071
26	G	A	-0.5594
27	Y	A	-0.1075
28	T	A	-0.0420
29	F	A	0.0000
30	T	A	-0.6415
31	S	A	-0.2018
32	Y	A	0.4074
33	N	A	-0.0695
34	M	A	0.0000
35	H	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	K	A	0.0000
39	Q	A	-0.4525
40	T	A	0.0000
41	P	A	-0.9567
42	G	A	-1.4167
43	R	A	-2.1748
44	G	A	-1.2189
45	L	A	0.0000
46	E	A	-0.7554
47	W	A	0.0000
48	I	A	0.0000
49	G	A	0.0000
50	A	A	0.0000
51	I	A	0.0000
52	Y	A	-0.6838
53	P	A	0.0000
54	G	A	-1.3613
55	N	A	-2.0437
56	G	A	-1.9727
57	D	A	-2.3377
58	T	A	-1.1099
59	S	A	-0.8519
60	Y	A	-1.0326
61	N	A	0.0000
62	Q	A	-2.6128
63	K	A	-2.7731
64	F	A	0.0000
65	K	A	-2.5802
66	G	A	-1.8108
67	K	A	-1.6075
68	A	A	0.0000
69	T	A	-0.8377
70	L	A	0.0000
71	T	A	-0.4328
72	A	A	-0.8866
73	D	A	-1.4821
74	K	A	-1.8160
75	S	A	-1.0762
76	S	A	-1.0805
77	S	A	-1.1568
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.5712
81	M	A	0.0000
82	Q	A	-1.3797
83	L	A	0.0000
84	S	A	-0.8983
85	S	A	-0.8477
86	L	A	0.0000
87	T	A	-1.2501
88	S	A	-1.4411
89	E	A	-2.1162
90	D	A	0.0000
91	S	A	-0.6447
92	A	A	0.0000
93	V	A	0.3142
94	Y	A	0.0000
95	Y	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	S	A	0.0000
100	T	A	0.0000
101	Y	A	1.7710
102	Y	A	1.6480
103	G	A	0.3718
104	G	A	0.0998
105	D	A	0.3964
106	W	A	0.9989
107	Y	A	0.6535
108	F	A	0.0000
109	N	A	-0.3283
110	V	A	-0.0880
111	W	A	-0.2855
112	G	A	0.0000
113	A	A	-0.5254
114	G	A	-0.3243
115	T	A	0.0000
116	T	A	-0.1743
117	V	A	0.0000
118	T	A	-0.5282
119	V	A	0.0000
120	S	A	-0.7099
121	A	A	-0.6828
122	A	A	-0.4150
123	S	A	-0.5694
124	T	A	-0.8171
125	K	A	-1.1245
126	G	A	-1.2919
127	P	A	-0.5504
128	S	A	-0.3398
129	V	A	0.0000
130	F	A	-0.5162
131	P	A	-0.8975
132	L	A	0.0000
133	A	A	-0.9868
134	P	A	0.0000
135	S	A	-1.0864
136	S	A	-1.0946
137	K	A	-1.0829
138	S	A	-0.6974
139	T	A	-0.7003
140	S	A	-0.7676
141	G	A	-0.9126
142	G	A	-0.8253
143	T	A	-0.5820
144	A	A	-0.3808
145	A	A	0.0000
146	L	A	0.0000
147	G	A	0.0000
148	C	A	0.0000
149	L	A	0.0000
150	V	A	0.0000
151	K	A	0.0000
152	D	A	-0.5192
153	Y	A	0.0000
154	F	A	0.0000
155	P	A	0.0000
156	E	A	-0.6846
157	P	A	-0.7118
158	V	A	-0.3663
159	T	A	-0.4993
160	V	A	-0.1361
161	S	A	-0.3342
162	W	A	0.0000
163	N	A	-0.5571
164	S	A	-0.6179
165	G	A	-0.5608
166	A	A	-0.2360
167	L	A	0.0403
168	T	A	-0.1701
169	S	A	-0.2026
170	G	A	-0.2733
171	V	A	0.0913
172	H	A	-0.1848
173	T	A	0.0175
174	F	A	0.0000
175	P	A	-0.3081
176	A	A	0.3841
177	V	A	0.7705
178	L	A	1.4018
179	Q	A	0.1543
180	S	A	-0.1845
181	S	A	-0.3393
182	G	A	-0.1963
183	L	A	0.1174
184	Y	A	0.5370
185	S	A	0.0000
186	L	A	0.4011
187	S	A	0.0000
188	S	A	0.0000
189	V	A	0.0000
190	V	A	0.0000
191	T	A	-0.2686
192	V	A	0.0000
193	P	A	-0.4911
194	S	A	-0.5708
195	S	A	-0.6253
196	S	A	-0.6073
197	L	A	-0.8022
198	G	A	-0.9165
199	T	A	-0.8106
200	Q	A	-1.1881
201	T	A	-1.0955
202	Y	A	0.0000
203	I	A	-1.0292
204	C	A	0.0000
205	N	A	-1.4680
206	V	A	0.0000
207	N	A	-1.7766
208	H	A	0.0000
209	K	A	-2.7050
210	P	A	-1.6172
211	S	A	-1.7766
212	N	A	-2.5173
213	T	A	-2.0429
214	K	A	-2.7288
215	V	A	-1.7902
216	D	A	-2.6096
217	K	A	-2.2550
218	K	A	-2.3040
219	V	A	0.0000
220	E	A	-2.5489
221	P	A	-1.8178
222	K	A	-1.9384
223	S	A	-1.1988