Project name: 34pro

Chain sequence(s)	A: MKVGIVGGGIVGLMSAYFLAKEGVSVTVYDPAPGKYSIHAAGLIEPYRFDRINTTSMIAKMLRFMRRGVTEVRQLNKMWVVELLSSLNKSPPQEAWDLMREMARLSLDTYAQMAEERNDFDYHNDGLLEVYTSEEELEKGEKEEKQSPFSPKFEVTEVPGFAGGIFFPELSRIATEKFVKRITRELTQLKVNFQGMEAQPNLKDYTLNGEKFDVVILANGVWITKSLKLPITAFKGYGAWVKGSSKIKNAFVTVDEGVAVSPLSDHVKITGGFSADYGSEWRTDILSKVTSLVKVEEVMERNMGFRPCSPDGFPIMGRLDNVVVATGACRLGWSYAPAMGYYASELALGKRSTLGYVSRYVDRLRSSE
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.3443
• Maximal score value: 1.8654
• Average score: -0.2563
• Total score value: -94.321

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.4543
2	K	A	-1.4783
3	V	A	0.0000
4	G	A	0.0000
5	I	A	0.0000
6	V	A	0.0000
7	G	A	0.0000
8	G	A	-0.0610
9	G	A	-0.0774
10	I	A	0.0000
11	V	A	0.2288
12	G	A	0.0000
13	L	A	0.0000
14	M	A	0.0000
15	S	A	0.0000
16	A	A	0.0000
17	Y	A	0.0000
18	F	A	0.4681
19	L	A	0.0000
20	A	A	0.0000
21	K	A	-1.9018
22	E	A	-1.5051
23	G	A	-0.6179
24	V	A	0.1153
25	S	A	-0.0617
26	V	A	0.0000
27	T	A	0.0000
28	V	A	0.0000
29	Y	A	0.0000
30	D	A	0.0000
31	P	A	0.0214
32	A	A	0.0888
33	P	A	-0.3152
34	G	A	-0.4268
35	K	A	-0.2319
36	Y	A	0.1207
37	S	A	0.0000
38	I	A	0.0336
39	H	A	-0.3008
40	A	A	-0.0540
41	A	A	0.0208
42	G	A	0.0000
43	L	A	0.0000
44	I	A	0.0000
45	E	A	0.0000
46	P	A	0.0000
47	Y	A	0.2048
48	R	A	0.0000
49	F	A	0.2544
50	D	A	0.0000
51	R	A	0.0000
52	I	A	1.4722
53	N	A	0.0545
54	T	A	0.0000
55	T	A	0.0000
56	S	A	0.0000
57	M	A	0.0000
58	I	A	0.0000
59	A	A	0.0000
60	K	A	-0.6802
61	M	A	0.0617
62	L	A	0.0496
63	R	A	-1.1236
64	F	A	0.0884
65	M	A	0.2707
66	R	A	-0.5323
67	R	A	-2.2273
68	G	A	-0.8526
69	V	A	0.1976
70	T	A	-0.2894
71	E	A	-1.4660
72	V	A	-0.2638
73	R	A	-1.4111
74	Q	A	-1.1432
75	L	A	0.0000
76	N	A	-1.2876
77	K	A	-0.8822
78	M	A	0.4544
79	W	A	0.0690
80	V	A	0.0000
81	V	A	0.4438
82	E	A	-0.5770
83	L	A	0.0000
84	L	A	0.3862
85	S	A	-0.2613
86	S	A	-0.2980
87	L	A	0.0000
88	N	A	-1.3708
89	K	A	-1.9285
90	S	A	-0.5770
91	P	A	-0.1992
92	P	A	0.0000
93	Q	A	-1.3461
94	E	A	-2.1234
95	A	A	0.0000
96	W	A	-0.2782
97	D	A	-1.1672
98	L	A	0.0000
99	M	A	0.0000
100	R	A	-0.4150
101	E	A	-0.3448
102	M	A	0.0000
103	A	A	0.0000
104	R	A	-0.4534
105	L	A	0.4976
106	S	A	0.0000
107	L	A	-0.0531
108	D	A	-1.2067
109	T	A	-0.2364
110	Y	A	0.0000
111	A	A	-0.1582
112	Q	A	-1.0198
113	M	A	0.0000
114	A	A	-0.3142
115	E	A	-1.9917
116	E	A	-1.4609
117	R	A	-1.1017
118	N	A	-0.9485
119	D	A	-1.8746
120	F	A	0.0000
121	D	A	-0.3466
122	Y	A	0.3138
123	H	A	-0.3293
124	N	A	-1.4619
125	D	A	-1.0844
126	G	A	0.0000
127	L	A	0.0000
128	L	A	0.0000
129	E	A	0.0000
130	V	A	0.0000
131	Y	A	0.0000
132	T	A	-0.0376
133	S	A	-0.4271
134	E	A	-2.1270
135	E	A	-2.3443
136	E	A	-0.5670
137	L	A	-0.2333
138	E	A	-1.7686
139	K	A	-0.7236
140	G	A	0.0000
141	E	A	-1.2805
142	K	A	-1.8921
143	E	A	-0.8719
144	E	A	-0.8918
145	K	A	-1.9542
146	Q	A	-1.2950
147	S	A	-0.0320
148	P	A	0.0904
149	F	A	1.6988
150	S	A	0.0000
151	P	A	-0.4075
152	K	A	-1.3052
153	F	A	0.7594
154	E	A	0.0000
155	V	A	1.7702
156	T	A	0.2687
157	E	A	-0.0548
158	V	A	0.6624
159	P	A	-0.2045
160	G	A	-0.4246
161	F	A	0.3975
162	A	A	0.0964
163	G	A	-0.0480
164	G	A	0.0000
165	I	A	0.0000
166	F	A	0.2993
167	F	A	0.2713
168	P	A	-0.5316
169	E	A	-1.8655
170	L	A	0.0000
171	S	A	0.0000
172	R	A	0.0000
173	I	A	0.0000
174	A	A	0.0000
175	T	A	0.0000
176	E	A	-1.0617
177	K	A	-0.7545
178	F	A	0.0000
179	V	A	0.0000
180	K	A	-0.9241
181	R	A	0.0000
182	I	A	0.0000
183	T	A	-0.2645
184	R	A	-1.4226
185	E	A	0.0000
186	L	A	0.0000
187	T	A	-0.2401
188	Q	A	-1.1318
189	L	A	-0.0435
190	K	A	-1.2655
191	V	A	-0.2331
192	N	A	-0.6447
193	F	A	0.4415
194	Q	A	-0.1162
195	G	A	0.0295
196	M	A	0.9854
197	E	A	-0.0136
198	A	A	-0.0254
199	Q	A	0.0000
200	P	A	-0.3847
201	N	A	-0.7219
202	L	A	-0.1506
203	K	A	-1.9168
204	D	A	-1.7163
205	Y	A	0.0000
206	T	A	-0.0709
207	L	A	0.0000
208	N	A	-1.3407
209	G	A	-0.7798
210	E	A	-1.1711
211	K	A	-1.1344
212	F	A	-0.1628
213	D	A	-0.8979
214	V	A	0.1999
215	V	A	0.0000
216	I	A	0.0000
217	L	A	0.0000
218	A	A	0.0000
219	N	A	0.0000
220	G	A	-0.0858
221	V	A	0.0000
222	W	A	0.6452
223	I	A	0.0000
224	T	A	-0.3624
225	K	A	-1.6237
226	S	A	-0.4500
227	L	A	-0.0682
228	K	A	-1.4781
229	L	A	0.0000
230	P	A	-0.0422
231	I	A	0.0000
232	T	A	-0.0545
233	A	A	0.0681
234	F	A	0.2149
235	K	A	-0.2951
236	G	A	0.0000
237	Y	A	0.0000
238	G	A	0.0000
239	A	A	0.0000
240	W	A	0.2107
241	V	A	0.0000
242	K	A	-1.0472
243	G	A	0.0000
244	S	A	-0.2515
245	S	A	-0.4739
246	K	A	-1.2088
247	I	A	0.0000
248	K	A	-0.7327
249	N	A	-0.3345
250	A	A	0.0000
251	F	A	0.0000
252	V	A	0.0000
253	T	A	0.0607
254	V	A	0.2832
255	D	A	-0.6810
256	E	A	-1.9140
257	G	A	-0.4408
258	V	A	0.0000
259	A	A	0.0000
260	V	A	0.0000
261	S	A	0.0000
262	P	A	0.0000
263	L	A	0.2252
264	S	A	-0.5066
265	D	A	-1.8302
266	H	A	0.0000
267	V	A	0.0000
268	K	A	-0.1336
269	I	A	0.0000
270	T	A	0.0000
271	G	A	-0.1019
272	G	A	0.0000
273	F	A	0.6354
274	S	A	0.0889
275	A	A	-0.3322
276	D	A	-1.5173
277	Y	A	0.9440
278	G	A	-0.0695
279	S	A	-0.5590
280	E	A	-1.8083
281	W	A	-0.0181
282	R	A	-0.2467
283	T	A	-0.5372
284	D	A	-1.2677
285	I	A	0.0000
286	L	A	0.1423
287	S	A	-0.3497
288	K	A	-0.4248
289	V	A	0.0000
290	T	A	-0.2479
291	S	A	-0.1853
292	L	A	0.1266
293	V	A	0.0000
294	K	A	-1.3808
295	V	A	1.3382
296	E	A	-0.4612
297	E	A	-0.4024
298	V	A	1.5955
299	M	A	0.7276
300	E	A	-0.9342
301	R	A	-2.0214
302	N	A	-0.6861
303	M	A	0.2420
304	G	A	0.0000
305	F	A	0.1832
306	R	A	-0.2507
307	P	A	0.0000
308	C	A	0.0989
309	S	A	0.0000
310	P	A	-0.0605
311	D	A	0.0000
312	G	A	-0.0749
313	F	A	0.0000
314	P	A	0.0000
315	I	A	0.0000
316	M	A	0.0000
317	G	A	0.0000
318	R	A	-0.6418
319	L	A	0.3243
320	D	A	-1.8015
321	N	A	-1.1610
322	V	A	0.1050
323	V	A	0.0000
324	V	A	0.0000
325	A	A	0.0000
326	T	A	0.0000
327	G	A	0.0000
328	A	A	0.0000
329	C	A	0.0244
330	R	A	-0.6228
331	L	A	0.0000
332	G	A	0.0000
333	W	A	0.0000
334	S	A	0.0000
335	Y	A	0.0000
336	A	A	0.0000
337	P	A	0.0000
338	A	A	0.0000
339	M	A	0.0000
340	G	A	0.0000
341	Y	A	1.0568
342	Y	A	0.0000
343	A	A	0.0000
344	S	A	0.0000
345	E	A	0.0000
346	L	A	0.1649
347	A	A	0.3410
348	L	A	1.4683
349	G	A	-0.3263
350	K	A	-1.2441
351	R	A	-1.9980
352	S	A	-0.3797
353	T	A	-0.0466
354	L	A	0.0684
355	G	A	-0.3345
356	Y	A	0.7972
357	V	A	1.8654
358	S	A	0.2798
359	R	A	0.0000
360	Y	A	0.4762
361	V	A	0.0000
362	D	A	-1.2768
363	R	A	-0.1704
364	L	A	1.5081
365	R	A	0.0000
366	S	A	-0.5468
367	S	A	-0.5822
368	E	A	-1.8915