Project name: OspC-C08

Chain sequence(s)	A: MKKNTLSAILMTLFLFISCNNSGKDGNASANSADESVKGPNLTEISKKITESNAVVLAVKEVEALLSSIDELAKAIGKKIENNGLGADANHNGSLLAGAYAISTLITEKLNGLKNSEELKEKIEKAKKCSEEFTKKLKSEHADLGVQNATDDNAKKAILKTNADKDKGAKELKKLSESVESLSKAAQEMLANSVKELTSPVVAESPKKP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.3898
• Maximal score value: 1.9326
• Average score: -1.1226
• Total score value: -234.629

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	-0.6060
2	K	A	-1.2906
3	K	A	-1.5068
4	N	A	-0.5927
5	T	A	0.0000
6	L	A	0.0000
7	S	A	0.0000
8	A	A	0.0000
9	I	A	0.7966
10	L	A	0.9568
11	M	A	0.6577
12	T	A	0.0000
13	L	A	0.0000
14	F	A	1.9326
15	L	A	1.8490
16	F	A	1.7124
17	I	A	0.0000
18	S	A	0.0000
19	C	A	-0.3345
20	N	A	-1.7320
21	N	A	-0.9191
22	S	A	-0.1602
23	G	A	0.0000
24	K	A	-2.7929
25	D	A	-2.7069
26	G	A	-1.5730
27	N	A	-2.6618
28	A	A	-1.7398
29	S	A	-1.3623
30	A	A	-1.2767
31	N	A	-1.8433
32	S	A	-1.8067
33	A	A	-1.7889
34	D	A	-2.7715
35	E	A	-2.5659
36	S	A	-1.6480
37	V	A	-0.8949
38	K	A	-1.3265
39	G	A	-0.1499
40	P	A	-0.5087
41	N	A	-0.8577
42	L	A	-0.7329
43	T	A	-1.3308
44	E	A	-2.3169
45	I	A	0.0000
46	S	A	-1.5874
47	K	A	-2.7884
48	K	A	-2.3729
49	I	A	-1.5583
50	T	A	-1.3895
51	E	A	-2.1298
52	S	A	0.0000
53	N	A	-1.0955
54	A	A	-0.8628
55	V	A	0.0000
56	V	A	0.0000
57	L	A	0.2420
58	A	A	-0.0884
59	V	A	0.0000
60	K	A	0.0611
61	E	A	0.0000
62	V	A	0.0000
63	E	A	-0.6269
64	A	A	0.0000
65	L	A	0.0000
66	L	A	0.0000
67	S	A	-0.4157
68	S	A	0.0000
69	I	A	0.0000
70	D	A	-1.5937
71	E	A	-2.5008
72	L	A	-1.4055
73	A	A	0.0000
74	K	A	-2.3824
75	A	A	-1.1919
76	I	A	0.0000
77	G	A	-1.7401
78	K	A	-1.5080
79	K	A	-0.6965
80	I	A	0.9170
81	E	A	-0.8202
82	N	A	-1.7522
83	N	A	-1.6089
84	G	A	-0.4768
85	L	A	0.5543
86	G	A	-0.3021
87	A	A	-0.5353
88	D	A	-1.2558
89	A	A	-1.6308
90	N	A	-2.2529
91	H	A	-2.2029
92	N	A	0.0000
93	G	A	-0.8583
94	S	A	-0.4441
95	L	A	-0.2121
96	L	A	0.0000
97	A	A	0.1170
98	G	A	0.0461
99	A	A	0.0000
100	Y	A	-0.0714
101	A	A	0.2015
102	I	A	0.0000
103	S	A	0.0000
104	T	A	-0.6808
105	L	A	-0.7075
106	I	A	0.0000
107	T	A	-1.9367
108	E	A	-2.5228
109	K	A	-1.7990
110	L	A	0.0000
111	N	A	-2.9001
112	G	A	-2.1707
113	L	A	0.0000
114	K	A	-2.4632
115	N	A	-2.9285
116	S	A	-2.8510
117	E	A	-3.7809
118	E	A	-3.5651
119	L	A	0.0000
120	K	A	-4.3898
121	E	A	-4.1557
122	K	A	-3.2289
123	I	A	0.0000
124	E	A	-4.1731
125	K	A	-3.5617
126	A	A	0.0000
127	K	A	-3.4837
128	K	A	-3.2379
129	C	A	0.0000
130	S	A	0.0000
131	E	A	-2.4961
132	E	A	-2.4442
133	F	A	0.0000
134	T	A	-1.6971
135	K	A	-2.9068
136	K	A	-2.5778
137	L	A	0.0000
138	K	A	-2.5725
139	S	A	-1.9365
140	E	A	-2.0262
141	H	A	-1.6728
142	A	A	-0.7061
143	D	A	-1.1800
144	L	A	0.0000
145	G	A	-0.6176
146	V	A	0.3199
147	Q	A	-1.3410
148	N	A	-1.7974
149	A	A	0.0000
150	T	A	-1.6940
151	D	A	-2.0349
152	D	A	-2.4362
153	N	A	-2.0789
154	A	A	0.0000
155	K	A	-1.9409
156	K	A	-2.4455
157	A	A	0.0000
158	I	A	0.0000
159	L	A	-1.4855
160	K	A	-1.3648
161	T	A	-0.8873
162	N	A	-1.4408
163	A	A	-0.9897
164	D	A	-2.5459
165	K	A	-3.0746
166	D	A	-3.1645
167	K	A	-2.4036
168	G	A	0.0000
169	A	A	0.0000
170	K	A	-3.2176
171	E	A	0.0000
172	L	A	0.0000
173	K	A	-2.4316
174	K	A	-2.4034
175	L	A	0.0000
176	S	A	0.0000
177	E	A	-3.0409
178	S	A	0.0000
179	V	A	0.0000
180	E	A	-3.1516
181	S	A	-2.2946
182	L	A	0.0000
183	S	A	0.0000
184	K	A	-2.9255
185	A	A	-2.1779
186	A	A	0.0000
187	Q	A	-2.3962
188	E	A	-2.8160
189	M	A	-2.0991
190	L	A	-1.4659
191	A	A	-1.8166
192	N	A	-2.6464
193	S	A	0.0000
194	V	A	-1.7906
195	K	A	-2.6134
196	E	A	-1.9854
197	L	A	0.0000
198	T	A	-1.7256
199	S	A	-0.7113
200	P	A	0.0003
201	V	A	1.5669
202	V	A	1.5143
203	A	A	0.2953
204	E	A	-0.8454
205	S	A	-0.5770
206	P	A	-1.4893
207	K	A	-2.7407
208	K	A	-2.8074
209	P	A	-1.5479