Project name: b653d6bd68128e2

Chain sequence(s)	A: DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISRIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRY
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6673
• Maximal score value: 3.5976
• Average score: 0.1729
• Total score value: 34.7495

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	D	A	-1.1704
3	W	A	0.2917
4	G	A	0.5708
5	T	A	0.5294
6	L	A	0.9722
7	Q	A	0.3747
8	T	A	1.1063
9	I	A	2.0448
10	L	A	1.4212
11	G	A	0.5582
12	G	A	0.1364
13	V	A	-0.3970
14	N	A	-1.7323
15	K	A	-2.3549
16	H	A	-1.4807
17	S	A	-0.5878
18	T	A	0.0371
19	S	A	1.1944
20	I	A	2.5756
21	G	A	0.0000
22	K	A	1.7563
23	I	A	3.3321
24	W	A	3.1275
25	L	A	0.0000
26	T	A	2.4067
27	V	A	3.5976
28	L	A	2.9449
29	F	A	2.4131
30	I	A	2.7924
31	F	A	2.8014
32	R	A	0.0000
33	I	A	2.1147
34	M	A	2.2072
35	I	A	2.0092
36	L	A	0.0000
37	V	A	1.0594
38	V	A	1.0966
39	A	A	0.0000
40	A	A	-1.1739
41	K	A	-2.3685
42	E	A	-2.4803
43	V	A	0.0000
44	W	A	0.0000
45	G	A	-2.2928
46	D	A	-2.8388
47	E	A	0.0000
48	Q	A	-2.3878
49	A	A	-1.6531
50	D	A	-2.2776
51	F	A	0.0000
52	V	A	0.1087
53	C	A	-0.5241
54	N	A	-0.8704
55	T	A	-0.2349
56	L	A	0.7060
57	Q	A	-0.4808
58	P	A	-0.5560
59	G	A	-0.4986
60	C	A	0.0000
61	K	A	-1.5599
62	N	A	-2.0285
63	V	A	-1.1515
64	C	A	0.0000
65	Y	A	0.0000
66	D	A	-2.4239
67	H	A	-1.7746
68	Y	A	-1.2534
69	F	A	0.0000
70	P	A	-0.2948
71	I	A	0.5857
72	S	A	-0.2610
73	R	A	0.0000
74	I	A	0.0000
75	R	A	-1.3003
76	L	A	0.0000
77	W	A	0.0000
78	A	A	0.2273
79	L	A	1.0384
80	Q	A	0.0000
81	L	A	0.0000
82	I	A	2.2779
83	F	A	2.0884
84	V	A	0.0000
85	S	A	1.1055
86	T	A	1.2826
87	P	A	0.0000
88	A	A	0.6463
89	L	A	0.8149
90	L	A	1.4272
91	V	A	0.0000
92	A	A	0.0000
93	M	A	0.9672
94	H	A	0.3233
95	V	A	0.0000
96	A	A	-0.1543
97	Y	A	-0.3037
98	R	A	-1.9925
99	R	A	-2.9400
100	H	A	-3.1869
101	E	A	-3.6673
102	K	A	-2.9752
103	K	A	-3.3754
104	R	A	-3.5143
105	K	A	-2.6016
106	F	A	0.1587
107	I	A	0.4513
108	K	A	-1.2998
109	G	A	-0.6615
125	K	A	-2.0468
126	V	A	-0.5765
127	R	A	-2.2972
128	I	A	0.0000
129	E	A	-2.0851
130	G	A	-1.2676
131	S	A	-0.8306
132	L	A	0.0000
133	W	A	-0.1589
134	W	A	0.6984
135	T	A	0.7590
136	Y	A	0.8202
137	T	A	1.3219
138	S	A	1.0358
139	S	A	0.0000
140	I	A	0.0000
141	F	A	2.3243
142	F	A	2.2417
143	R	A	0.0000
144	V	A	2.1271
145	I	A	2.2662
146	F	A	2.0058
147	E	A	0.0000
148	A	A	1.2711
149	A	A	1.3735
150	F	A	1.7907
151	M	A	1.7851
152	Y	A	2.5726
153	V	A	2.2811
154	F	A	0.0000
155	Y	A	2.6808
156	V	A	2.6375
157	M	A	1.6212
158	Y	A	0.0000
159	D	A	-1.0366
160	G	A	0.1589
161	F	A	2.0542
162	S	A	0.6046
163	M	A	-1.0407
164	Q	A	-2.2360
165	R	A	-2.3173
166	L	A	-0.7645
167	V	A	-1.0014
168	K	A	-1.8450
169	C	A	0.0000
170	N	A	-1.7891
171	A	A	0.0000
172	W	A	0.5675
173	P	A	-0.2780
174	C	A	0.0000
175	P	A	-0.8416
176	N	A	-1.5342
177	T	A	-1.5438
178	V	A	0.0000
179	D	A	-1.2252
180	C	A	0.0000
181	F	A	-0.5625
182	V	A	0.0000
183	S	A	0.0000
184	R	A	-2.9410
185	P	A	0.0000
186	T	A	-1.5307
187	E	A	-1.4600
188	K	A	0.0000
189	T	A	0.3688
190	V	A	0.8574
191	F	A	1.3134
192	T	A	0.0000
193	V	A	2.2347
194	F	A	2.3194
195	M	A	0.0000
196	I	A	1.7261
197	A	A	1.3061
198	V	A	0.0000
199	S	A	0.0000
200	G	A	1.1817
201	I	A	1.8245
202	C	A	0.0000
203	I	A	1.8930
204	L	A	2.4132
205	L	A	0.0000
206	N	A	0.0000
207	V	A	2.4308
208	T	A	1.5198
209	E	A	0.0000
210	L	A	2.2075
211	C	A	2.3092
212	Y	A	2.0971
213	L	A	2.3079
214	L	A	3.0033
215	I	A	2.7066
216	R	A	0.4689
217	Y	A	1.8710