Project name: Antibody1

Chain sequence(s)	G: SELTQDPAVSVALGQTVRVTCQGDSLRSYYASWYQQKPGQAPVLVIYGKNNRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCSSRDSSGNHWVFGGGTELTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT; F: VQLQQSGAEVKKPGSSVRVSCKASGGTFNNNAINWVRQAPGQGLEWMGGIIPMFGTAKYSQNFQGRVAITADESTGTASMELSSLRSEDTAVYYCARSRDLLLFPHHALSPWGRGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1393
• Maximal score value: 2.4557
• Average score: -0.7273
• Total score value: -314.9201

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	S	G	-1.4350
3	E	G	-2.3346
4	L	G	0.0000
5	T	G	-1.5257
6	Q	G	-1.4497
7	D	G	-2.3603
8	P	G	-1.6846
9	A	G	-1.3139
10	V	G	-1.0123
11	S	G	-0.3095
12	V	G	0.0000
13	A	G	-0.0100
14	L	G	-0.1434
15	G	G	-0.8363
16	Q	G	-1.0674
17	T	G	-1.1144
18	V	G	0.0000
19	R	G	-1.9003
20	V	G	0.0000
21	T	G	-1.1772
22	C	G	0.0000
23	Q	G	-2.4536
24	G	G	-2.4996
25	D	G	-2.8555
26	S	G	0.0000
27	L	G	0.0000
28	R	G	-2.9374
29	S	G	-1.4084
30	Y	G	-0.6978
31	Y	G	-0.5075
32	A	G	0.0000
33	S	G	0.0000
34	W	G	0.0000
35	Y	G	0.0000
36	Q	G	0.0000
37	Q	G	-0.9312
38	K	G	-1.7439
39	P	G	-1.4641
40	G	G	-1.4323
41	Q	G	-1.9326
42	A	G	-1.0416
43	P	G	0.0000
44	V	G	0.9819
45	L	G	0.0000
46	V	G	0.0000
47	I	G	0.0000
48	Y	G	-1.1943
49	G	G	0.0000
50	K	G	-2.6114
51	N	G	-2.4967
52	N	G	-2.3139
53	R	G	-2.3089
54	P	G	-0.7871
55	S	G	-0.7766
56	G	G	-0.8978
57	I	G	-0.7955
58	P	G	-1.3101
59	D	G	-2.2076
60	R	G	-1.3199
61	F	G	0.0000
62	S	G	-1.5909
63	G	G	-1.4566
64	S	G	-1.1660
65	S	G	-1.4063
66	S	G	-1.3576
67	G	G	-2.2347
68	N	G	-2.8843
69	T	G	-1.8555
70	A	G	0.0000
71	S	G	-0.8439
72	L	G	0.0000
73	T	G	-0.9320
74	I	G	0.0000
75	T	G	-1.1642
76	G	G	-1.1030
77	A	G	0.0000
78	Q	G	-1.1919
79	A	G	-1.1207
80	E	G	-1.8973
81	D	G	0.0000
82	E	G	-1.2573
83	A	G	-1.3448
84	D	G	-1.4565
85	Y	G	0.0000
86	Y	G	0.0000
87	C	G	0.0000
88	S	G	0.0000
89	S	G	0.0000
90	R	G	-0.5433
91	D	G	-1.1317
92	S	G	-1.3173
93	S	G	-0.6271
94	G	G	-0.5324
95	N	G	-0.7944
96	H	G	-0.6100
97	W	G	-0.2050
98	V	G	-0.4889
99	F	G	-0.4026
100	G	G	0.0000
101	G	G	-1.3549
102	G	G	0.0000
103	T	G	0.0000
104	E	G	-2.3444
105	L	G	0.0000
106	T	G	-0.3082
107	V	G	0.0000
108	L	G	0.6795
109	G	G	-0.1218
110	Q	G	0.0000
111	P	G	-0.9872
112	K	G	-2.1527
113	A	G	-1.2922
114	A	G	-0.8311
115	P	G	0.0000
116	S	G	-0.5090
117	V	G	0.0000
118	T	G	-0.4287
119	L	G	0.0000
120	F	G	0.0000
121	P	G	-0.1142
122	P	G	-0.3789
123	S	G	-0.8606
124	S	G	-1.3585
125	E	G	-1.4868
126	E	G	0.0000
127	L	G	-1.7900
128	Q	G	-2.0783
129	A	G	-1.7126
130	N	G	-2.5611
131	K	G	-2.4763
132	A	G	0.0000
133	T	G	0.0000
134	L	G	0.0000
135	V	G	0.0000
136	C	G	0.0000
137	L	G	0.0000
138	I	G	0.0000
139	S	G	-0.6116
140	D	G	-1.2622
141	F	G	0.0000
142	Y	G	-1.1028
143	P	G	-0.8957
144	G	G	-0.6266
145	A	G	-0.2170
146	V	G	-0.1448
147	T	G	-0.1657
148	V	G	0.0247
149	A	G	-0.4072
150	W	G	0.0000
151	K	G	-0.9552
152	A	G	0.0000
153	D	G	-1.3187
154	S	G	-0.8694
155	S	G	-0.8179
156	P	G	-0.9181
157	V	G	-0.8240
158	K	G	-1.5995
159	A	G	-0.7325
160	G	G	-0.4222
161	V	G	-0.1239
162	E	G	-0.1070
163	T	G	0.0801
164	T	G	0.0000
165	T	G	0.0514
166	P	G	-0.2176
167	S	G	-0.5525
168	K	G	-1.2289
169	Q	G	-1.2842
170	S	G	-1.2920
171	N	G	-1.9713
172	N	G	-1.7955
173	K	G	-1.8332
174	Y	G	-0.8249
175	A	G	0.0000
176	A	G	0.0000
177	S	G	0.0000
178	S	G	0.0000
179	Y	G	0.0000
180	L	G	0.0000
181	S	G	-0.5347
182	L	G	0.0000
183	T	G	-1.8237
184	P	G	-2.4669
185	E	G	-3.1393
186	Q	G	-2.3751
187	W	G	0.0000
188	K	G	-3.1012
189	S	G	-2.4125
190	H	G	-2.3846
191	R	G	-2.5363
192	S	G	-1.5121
193	Y	G	0.0000
194	S	G	0.0000
195	C	G	0.0000
196	Q	G	-1.0987
197	V	G	0.0000
198	T	G	-0.7461
199	H	G	0.0000
200	E	G	-2.3009
201	G	G	-1.4576
202	S	G	-0.9089
203	T	G	-0.7862
204	V	G	-0.7566
205	E	G	-2.0243
206	K	G	-1.6579
207	T	G	-0.9336
208	V	G	-0.3773
209	A	G	-0.8386
210	P	G	-0.9804
211	T	G	-0.6633
2	V	F	1.0786
3	Q	F	-1.0725
4	L	F	0.0000
5	Q	F	-2.3001
6	Q	F	-1.4794
7	S	F	-1.3447
8	G	F	-1.1204
9	A	F	0.0000
10	E	F	-1.2756
11	V	F	-0.7333
12	K	F	-1.6161
13	K	F	-2.3201
14	P	F	-1.9295
15	G	F	-1.3890
16	S	F	-1.1457
17	S	F	-1.2610
18	V	F	0.0000
19	R	F	-2.3791
20	V	F	0.0000
21	S	F	-1.1371
22	C	F	0.0000
23	K	F	-1.8517
24	A	F	-1.3017
25	S	F	-0.9255
26	G	F	-0.7442
27	G	F	-1.3137
28	T	F	-1.5284
29	F	F	0.0000
30	N	F	-1.6224
31	N	F	-0.5137
32	N	F	0.0000
33	A	F	0.0000
34	I	F	0.0000
35	N	F	0.0000
36	W	F	0.0000
37	V	F	0.0000
38	R	F	-0.6405
39	Q	F	-0.8362
40	A	F	-1.1040
41	P	F	-1.0848
42	G	F	-1.2496
43	Q	F	-1.8109
44	G	F	-1.2848
45	L	F	0.0000
46	E	F	-1.0035
47	W	F	0.0000
48	M	F	0.0000
49	G	F	0.0000
50	G	F	0.0000
51	I	F	0.4220
52	I	F	0.2176
53	P	F	-0.3925
54	M	F	0.4126
55	F	F	1.1782
56	G	F	0.2745
57	T	F	0.0685
58	A	F	0.0120
59	K	F	-0.4719
60	Y	F	-0.3682
61	S	F	-1.1563
62	Q	F	-2.0961
63	N	F	-2.2462
64	F	F	0.0000
65	Q	F	-2.1026
66	G	F	-1.5062
67	R	F	-1.1936
68	V	F	-1.0098
69	A	F	-0.6040
70	I	F	0.0000
71	T	F	-0.6030
72	A	F	-1.1405
73	D	F	-2.3071
74	E	F	-2.5410
75	S	F	-1.5290
76	T	F	-1.3811
77	G	F	0.0000
78	T	F	-1.5919
79	A	F	0.0000
80	S	F	0.0000
81	M	F	0.0000
82	E	F	-1.8081
83	L	F	0.0000
84	S	F	-1.1752
85	S	F	-1.0782
86	L	F	0.0000
87	R	F	-2.4343
88	S	F	-2.0888
89	E	F	-2.3968
90	D	F	0.0000
91	T	F	-0.8850
92	A	F	0.0000
93	V	F	0.0306
94	Y	F	0.0000
95	Y	F	0.0000
96	C	F	0.0000
97	A	F	0.0000
98	R	F	-0.3038
99	S	F	0.0000
100	R	F	-0.3339
101	D	F	0.7739
102	L	F	1.7111
103	L	F	2.4557
104	L	F	2.0340
105	F	F	1.1852
106	P	F	0.6151
107	H	F	-0.7677
108	H	F	-0.6997
109	A	F	0.0000
110	L	F	0.0000
111	S	F	0.0679
112	P	F	0.0390
113	W	F	-0.3536
114	G	F	0.0000
115	R	F	-2.3925
116	G	F	0.0000
117	T	F	0.0000
118	M	F	-0.0267
119	V	F	0.0000
120	T	F	-0.6371
121	V	F	0.0000
122	S	F	-1.0628
123	S	F	-0.9150
124	A	F	-0.5704
125	S	F	-0.6917
126	T	F	-0.7721
127	K	F	-1.0498
128	G	F	-1.3269
129	P	F	0.0000
130	S	F	-0.2880
131	V	F	0.0000
132	F	F	-0.3494
133	P	F	0.0000
134	L	F	0.0000
135	A	F	-1.1317
136	P	F	0.0000
137	S	F	-0.9869
138	S	F	-1.4137
139	K	F	-2.0533
140	S	F	-1.4260
141	T	F	-0.9087
142	S	F	-0.8958
143	G	F	-1.0274
144	G	F	-1.2001
145	T	F	-0.8773
146	A	F	0.0000
147	A	F	-0.0804
148	L	F	0.0000
149	G	F	0.0000
150	C	F	0.0000
151	L	F	0.0000
152	V	F	0.0000
153	K	F	-0.2448
154	D	F	-0.3494
155	Y	F	0.0000
156	F	F	-0.1680
157	P	F	0.0000
158	E	F	-0.3643
159	P	F	-0.6646
160	V	F	0.0000
161	T	F	-0.5194
162	V	F	-0.2707
163	S	F	-0.4592
164	W	F	0.0000
165	N	F	-0.8164
166	S	F	-0.7021
167	G	F	-0.5961
168	A	F	-0.2416
169	L	F	0.0551
170	T	F	-0.1602
171	S	F	-0.1947
172	G	F	-0.2265
173	V	F	0.2486
174	H	F	-0.0654
175	T	F	0.0270
176	F	F	0.0000
177	P	F	-0.1069
178	A	F	0.2617
179	V	F	0.0000
180	L	F	1.1650
181	Q	F	0.2991
182	S	F	-0.1692
183	S	F	-0.1778
184	G	F	0.0966
185	L	F	0.2788
186	Y	F	0.4676
187	S	F	0.0000
188	L	F	0.0000
189	S	F	0.0000
190	S	F	0.0000
191	V	F	0.1746
192	V	F	0.0000
193	T	F	-0.1666
194	V	F	0.0000
195	P	F	-0.6220
196	S	F	-1.0571
197	S	F	-0.7985
198	S	F	-0.6071
199	L	F	-0.9914
200	G	F	-1.0215
201	T	F	-0.8010
202	Q	F	-1.4213
203	T	F	-1.2171
204	Y	F	0.0000
205	I	F	-1.1981
206	C	F	0.0000
207	N	F	-1.4614
208	V	F	0.0000
209	N	F	-2.0822
210	H	F	0.0000
211	K	F	-2.9087
212	P	F	-1.7984
213	S	F	-1.8492
214	N	F	-2.6055
215	T	F	-2.1346
216	K	F	-2.6870
217	V	F	-1.4532
218	D	F	-2.4016
219	K	F	-1.9528
220	K	F	-2.4990
221	V	F	0.0000
222	E	F	-2.5356
223	P	F	-1.8311
224	K	F	-2.2175