| Chain sequence(s) |
A: NGTPQNITDLCAEYHNTQIHTLNDKIFSYTESLAGKREMAIITFKNGATFQVEVPGSQHIDSQKKAIERMKDTLRIAYLTEAKVEKLCVWNNKTPHAIAAISMANEAAAKKKEALAYECEARKLWEEAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEGPGPGGYLTAWAGPKLEKDIPYNLKSEAQGATGPGPGGSLNTCWSFSGMSTLEAYLKLKGYGTGPGPGLTGAQVISEELGYDLKEADLSMLGRASSVKVTKGPGPGVEEGIVAGGGTAFVSVIPAIGTLGPGPGKSMEKLSSGVRIKRAADDAAGLAISEGPGPGDVASEMVNLSKMNILVQASQSMLAQANQQPQGVLAAYSVTSGYAHYSTYFNKDETAYAAYMQFDRGFVSAYMVTDVDKMEAAAKGVFKGPDGFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGVFKGPNGFEYFAPANTDANNIEGQAILYQNEFLTLNGKKYYFGSDSKAVTGVFKGPNGFEYFAPANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIYYFGNNSKAVTEAAAKGVFSTEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFTAVVGVFDTSDGYKYFAPANTVNDNIYGQAVEYSGLVRVGEDVYYFGETYTIETGWIGVFNTPDGFKYFAHQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATHHHHHH |
| Distance of aggregation | 5 Å |
| Dynamic mode | No |
| Mutated residues | AA150C, GA197C |
| Energy difference between WT (input) and mutated protein (by FoldX) | 0.698426 kcal/mol
Changes in protein stability upon mutation are calculated using the FoldX forcefield. Computational prediction of protein stability is used with the intention of preventing the experimental characterization of proteins bearing mutations that significantly destabilize their structure. Mutations resulting in a predicted reduction in protein stability ≥ 1 kcal/mol are considered disruptive. |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | N | A | -1.3604 | |
| 2 | G | A | -0.7183 | |
| 3 | T | A | -0.1760 | |
| 4 | P | A | -0.4221 | |
| 5 | Q | A | -1.3293 | |
| 6 | N | A | -0.8224 | |
| 7 | I | A | 0.0000 | |
| 8 | T | A | -0.1729 | |
| 9 | D | A | -0.7511 | |
| 10 | L | A | 0.5219 | |
| 11 | C | A | 0.0000 | |
| 12 | A | A | -0.2743 | |
| 13 | E | A | -1.6617 | |
| 14 | Y | A | 0.2947 | |
| 15 | H | A | -1.0715 | |
| 16 | N | A | -1.4558 | |
| 17 | T | A | -0.3743 | |
| 18 | Q | A | -0.7844 | |
| 19 | I | A | 0.2759 | |
| 20 | H | A | -0.1278 | |
| 21 | T | A | -0.1076 | |
| 22 | L | A | -0.0558 | |
| 23 | N | A | -1.5206 | |
| 24 | D | A | -0.9627 | |
| 25 | K | A | -0.9402 | |
| 26 | I | A | 0.0000 | |
| 27 | F | A | 1.9306 | |
| 28 | S | A | 0.3300 | |
| 29 | Y | A | 0.1310 | |
| 30 | T | A | -0.1781 | |
| 31 | E | A | -0.8084 | |
| 32 | S | A | -0.1450 | |
| 33 | L | A | 0.2779 | |
| 34 | A | A | 0.0298 | |
| 35 | G | A | -0.7782 | |
| 36 | K | A | -2.1261 | |
| 37 | R | A | -2.2019 | |
| 38 | E | A | -0.5217 | |
| 39 | M | A | 0.0665 | |
| 40 | A | A | 0.0000 | |
| 41 | I | A | 0.3683 | |
| 42 | I | A | 0.0000 | |
| 43 | T | A | -0.0203 | |
| 44 | F | A | 0.0000 | |
| 45 | K | A | -1.9332 | |
| 46 | N | A | -1.6696 | |
| 47 | G | A | -0.6968 | |
| 48 | A | A | -0.0804 | |
| 49 | T | A | -0.0273 | |
| 50 | F | A | 0.0000 | |
| 51 | Q | A | -0.1025 | |
| 52 | V | A | 0.0000 | |
| 53 | E | A | -0.2423 | |
| 54 | V | A | 0.1905 | |
| 55 | P | A | -0.0047 | |
| 56 | G | A | -0.1211 | |
| 57 | S | A | -0.4466 | |
| 58 | Q | A | -1.2751 | |
| 59 | H | A | -0.0513 | |
| 60 | I | A | 1.5653 | |
| 61 | D | A | -1.5358 | |
| 62 | S | A | -0.6442 | |
| 63 | Q | A | -0.7839 | |
| 64 | K | A | -1.3151 | |
| 65 | K | A | -0.5613 | |
| 66 | A | A | 0.0000 | |
| 67 | I | A | 0.0000 | |
| 68 | E | A | -0.2839 | |
| 69 | R | A | -0.2296 | |
| 70 | M | A | 0.0000 | |
| 71 | K | A | 0.0000 | |
| 72 | D | A | -0.2957 | |
| 73 | T | A | 0.0000 | |
| 74 | L | A | 0.0000 | |
| 75 | R | A | -0.2438 | |
| 76 | I | A | 0.2281 | |
| 77 | A | A | 0.0000 | |
| 78 | Y | A | 0.4472 | |
| 79 | L | A | 1.1480 | |
| 80 | T | A | -0.0339 | |
| 81 | E | A | -1.2040 | |
| 82 | A | A | -0.5355 | |
| 83 | K | A | -1.8394 | |
| 84 | V | A | 0.0000 | |
| 85 | E | A | -1.7279 | |
| 86 | K | A | -0.5552 | |
| 87 | L | A | 0.0000 | |
| 88 | C | A | 0.0000 | |
| 89 | V | A | 0.0000 | |
| 90 | W | A | 0.1380 | |
| 91 | N | A | -1.0097 | |
| 92 | N | A | -1.6192 | |
| 93 | K | A | -1.2955 | |
| 94 | T | A | -0.2736 | |
| 95 | P | A | -0.1077 | |
| 96 | H | A | -0.1794 | |
| 97 | A | A | 0.0000 | |
| 98 | I | A | 0.0000 | |
| 99 | A | A | 0.0112 | |
| 100 | A | A | 0.0000 | |
| 101 | I | A | 0.0000 | |
| 102 | S | A | 0.0000 | |
| 103 | M | A | 0.4122 | |
| 104 | A | A | -0.1261 | |
| 105 | N | A | -1.3812 | |
| 106 | E | A | -0.8490 | |
| 107 | A | A | -0.0950 | |
| 108 | A | A | 0.0143 | |
| 109 | A | A | -0.1271 | |
| 110 | K | A | -1.0557 | |
| 111 | K | A | -2.0175 | |
| 112 | K | A | -1.2985 | |
| 113 | E | A | 0.0000 | |
| 114 | A | A | 0.1741 | |
| 115 | L | A | 0.9261 | |
| 116 | A | A | 0.0000 | |
| 117 | Y | A | -0.1878 | |
| 118 | E | A | -1.6828 | |
| 119 | C | A | 0.1255 | |
| 120 | E | A | -0.6247 | |
| 121 | A | A | 0.0000 | |
| 122 | R | A | -1.6520 | |
| 123 | K | A | -1.7014 | |
| 124 | L | A | -0.1538 | |
| 125 | W | A | -0.2559 | |
| 126 | E | A | -1.9602 | |
| 127 | E | A | -1.4436 | |
| 128 | A | A | 0.0000 | |
| 129 | E | A | -1.2178 | |
| 130 | K | A | -1.9082 | |
| 131 | Y | A | 0.0938 | |
| 132 | W | A | 0.1452 | |
| 133 | D | A | -1.8002 | |
| 134 | E | A | -0.7304 | |
| 135 | Y | A | 0.5062 | |
| 136 | S | A | -0.3571 | |
| 137 | K | A | -1.4854 | |
| 138 | Y | A | 0.8163 | |
| 139 | N | A | -0.5505 | |
| 140 | Y | A | 0.8202 | |
| 141 | K | A | -1.4617 | |
| 142 | G | A | 0.0000 | |
| 143 | I | A | 0.5252 | |
| 144 | E | A | -0.7660 | |
| 145 | Y | A | 0.1031 | |
| 146 | L | A | 0.1986 | |
| 147 | A | A | -0.0865 | |
| 148 | E | A | -0.2081 | |
| 149 | A | A | 0.0000 | |
| 150 | C | A | 0.1453 | mutated: AA150C |
| 151 | R | A | -0.1404 | |
| 152 | L | A | 0.0000 | |
| 153 | F | A | 0.0483 | |
| 154 | D | A | -1.7628 | |
| 155 | E | A | -0.5696 | |
| 156 | G | A | -0.0351 | |
| 157 | M | A | 0.0877 | |
| 158 | E | A | -0.2307 | |
| 159 | C | A | -0.2501 | |
| 160 | E | A | -1.6580 | |
| 161 | G | A | -0.7689 | |
| 162 | P | A | -0.1320 | |
| 163 | G | A | 0.0000 | |
| 164 | P | A | -0.1441 | |
| 165 | G | A | -0.2892 | |
| 166 | G | A | -0.0468 | |
| 167 | Y | A | 0.2769 | |
| 168 | L | A | 0.2208 | |
| 169 | T | A | -0.0317 | |
| 170 | A | A | 0.0593 | |
| 171 | W | A | 0.3006 | |
| 172 | A | A | 0.0822 | |
| 173 | G | A | 0.0000 | |
| 174 | P | A | -0.5420 | |
| 175 | K | A | -1.6087 | |
| 176 | L | A | 0.1936 | |
| 177 | E | A | 0.0000 | |
| 178 | K | A | -0.7688 | |
| 179 | D | A | -1.6891 | |
| 180 | I | A | 0.2237 | |
| 181 | P | A | 0.0000 | |
| 182 | Y | A | 0.5093 | |
| 183 | N | A | -1.0217 | |
| 184 | L | A | 0.1204 | |
| 185 | K | A | 0.0000 | |
| 186 | S | A | -0.3933 | |
| 187 | E | A | -1.8775 | |
| 188 | A | A | -0.3953 | |
| 189 | Q | A | -0.5045 | |
| 190 | G | A | -0.7226 | |
| 191 | A | A | -0.0389 | |
| 192 | T | A | -0.1291 | |
| 193 | G | A | -0.4116 | |
| 194 | P | A | -0.2952 | |
| 195 | G | A | -0.2321 | |
| 196 | P | A | -0.0746 | |
| 197 | C | A | -0.0155 | mutated: GA197C |
| 198 | G | A | -0.2996 | |
| 199 | S | A | 0.0000 | |
| 200 | L | A | 0.0600 | |
| 201 | N | A | -0.3457 | |
| 202 | T | A | -0.0855 | |
| 203 | C | A | 0.0000 | |
| 204 | W | A | 0.1395 | |
| 205 | S | A | 0.0000 | |
| 206 | F | A | 0.4569 | |
| 207 | S | A | -0.0358 | |
| 208 | G | A | 0.0000 | |
| 209 | M | A | 0.3262 | |
| 210 | S | A | -0.1448 | |
| 211 | T | A | 0.0000 | |
| 212 | L | A | 0.1726 | |
| 213 | E | A | 0.0000 | |
| 214 | A | A | 0.0000 | |
| 215 | Y | A | 0.0000 | |
| 216 | L | A | 0.0000 | |
| 217 | K | A | -0.2891 | |
| 218 | L | A | 0.0000 | |
| 219 | K | A | -1.2343 | |
| 220 | G | A | -0.4826 | |
| 221 | Y | A | 0.3170 | |
| 222 | G | A | -0.3819 | |
| 223 | T | A | -0.0982 | |
| 224 | G | A | 0.0000 | |
| 225 | P | A | 0.0000 | |
| 226 | G | A | 0.0000 | |
| 227 | P | A | 0.0000 | |
| 228 | G | A | 0.0000 | |
| 229 | L | A | 0.0000 | |
| 230 | T | A | -0.1265 | |
| 231 | G | A | -0.2972 | |
| 232 | A | A | -0.1231 | |
| 233 | Q | A | -0.8738 | |
| 234 | V | A | 0.0662 | |
| 235 | I | A | 0.0000 | |
| 236 | S | A | -0.0355 | |
| 237 | E | A | 0.0000 | |
| 238 | E | A | -0.2833 | |
| 239 | L | A | 0.0000 | |
| 240 | G | A | 0.0038 | |
| 241 | Y | A | 0.0403 | |
| 242 | D | A | -1.5523 | |
| 243 | L | A | 0.2608 | |
| 244 | K | A | -1.7238 | |
| 245 | E | A | -1.3327 | |
| 246 | A | A | -0.3355 | |
| 247 | D | A | -0.9435 | |
| 248 | L | A | 0.4986 | |
| 249 | S | A | 0.2415 | |
| 250 | M | A | 0.7973 | |
| 251 | L | A | 0.7022 | |
| 252 | G | A | -0.3430 | |
| 253 | R | A | -1.9482 | |
| 254 | A | A | -0.3676 | |
| 255 | S | A | -0.1820 | |
| 256 | S | A | -0.2392 | |
| 257 | V | A | 0.0000 | |
| 258 | K | A | -0.5264 | |
| 259 | V | A | 0.0000 | |
| 260 | T | A | -0.0206 | |
| 261 | K | A | 0.0000 | |
| 262 | G | A | 0.0000 | |
| 263 | P | A | -0.1703 | |
| 264 | G | A | -0.4838 | |
| 265 | P | A | -0.2619 | |
| 266 | G | A | 0.0000 | |
| 267 | V | A | 0.0000 | |
| 268 | E | A | -0.2633 | |
| 269 | E | A | -0.4470 | |
| 270 | G | A | 0.0000 | |
| 271 | I | A | 0.8746 | |
| 272 | V | A | 0.9525 | |
| 273 | A | A | 0.1226 | |
| 274 | G | A | -0.4947 | |
| 275 | G | A | -0.3116 | |
| 276 | G | A | -0.1635 | |
| 277 | T | A | 0.0000 | |
| 278 | A | A | 0.0000 | |
| 279 | F | A | 0.0000 | |
| 280 | V | A | 0.2172 | |
| 281 | S | A | 0.0000 | |
| 282 | V | A | 0.0000 | |
| 283 | I | A | 0.4431 | |
| 284 | P | A | 0.0234 | |
| 285 | A | A | 0.4153 | |
| 286 | I | A | 1.9961 | |
| 287 | G | A | 0.2302 | |
| 288 | T | A | -0.0350 | |
| 289 | L | A | 0.0000 | |
| 290 | G | A | 0.0000 | |
| 291 | P | A | 0.0000 | |
| 292 | G | A | 0.0000 | |
| 293 | P | A | -0.0277 | |
| 294 | G | A | 0.0000 | |
| 295 | K | A | -0.4144 | |
| 296 | S | A | 0.0000 | |
| 297 | M | A | -0.0871 | |
| 298 | E | A | -1.9189 | |
| 299 | K | A | -1.1705 | |
| 300 | L | A | 0.0000 | |
| 301 | S | A | -0.0538 | |
| 302 | S | A | -0.1835 | |
| 303 | G | A | -0.1641 | |
| 304 | V | A | -0.3328 | |
| 305 | R | A | -1.4452 | |
| 306 | I | A | 1.4524 | |
| 307 | K | A | -1.1697 | |
| 308 | R | A | -2.0581 | |
| 309 | A | A | -0.2703 | |
| 310 | A | A | -0.4170 | |
| 311 | D | A | -2.1069 | |
| 312 | D | A | -2.1114 | |
| 313 | A | A | -0.3039 | |
| 314 | A | A | -0.0148 | |
| 315 | G | A | -0.1205 | |
| 316 | L | A | 1.4803 | |
| 317 | A | A | 0.1229 | |
| 318 | I | A | 0.0000 | |
| 319 | S | A | -0.5483 | |
| 320 | E | A | -1.8660 | |
| 321 | G | A | -0.4023 | |
| 322 | P | A | -0.1081 | |
| 323 | G | A | -0.3701 | |
| 324 | P | A | -0.3231 | |
| 325 | G | A | -0.4273 | |
| 326 | D | A | -1.7992 | |
| 327 | V | A | 0.0000 | |
| 328 | A | A | -0.0253 | |
| 329 | S | A | -0.2579 | |
| 330 | E | A | -0.2984 | |
| 331 | M | A | 0.0000 | |
| 332 | V | A | 0.1511 | |
| 333 | N | A | -0.2275 | |
| 334 | L | A | 1.4016 | |
| 335 | S | A | -0.0981 | |
| 336 | K | A | -0.7660 | |
| 337 | M | A | 0.6466 | |
| 338 | N | A | -1.0397 | |
| 339 | I | A | 0.1801 | |
| 340 | L | A | 1.1393 | |
| 341 | V | A | 0.3265 | |
| 342 | Q | A | -1.1235 | |
| 343 | A | A | -0.1799 | |
| 344 | S | A | 0.0000 | |
| 345 | Q | A | -1.2196 | |
| 346 | S | A | -0.3176 | |
| 347 | M | A | 0.1155 | |
| 348 | L | A | 0.2093 | |
| 349 | A | A | 0.0000 | |
| 350 | Q | A | -0.1582 | |
| 351 | A | A | -0.0227 | |
| 352 | N | A | 0.0000 | |
| 353 | Q | A | -0.4565 | |
| 354 | Q | A | 0.0000 | |
| 355 | P | A | -0.2857 | |
| 356 | Q | A | -0.2334 | |
| 357 | G | A | -0.0495 | |
| 358 | V | A | 0.4005 | |
| 359 | L | A | 0.0000 | |
| 360 | A | A | 0.0000 | |
| 361 | A | A | 0.1097 | |
| 362 | Y | A | 0.2784 | |
| 363 | S | A | 0.1521 | |
| 364 | V | A | 0.7240 | |
| 365 | T | A | 0.0633 | |
| 366 | S | A | -0.2287 | |
| 367 | G | A | 0.1570 | |
| 368 | Y | A | 1.3162 | |
| 369 | A | A | 0.1964 | |
| 370 | H | A | -0.4344 | |
| 371 | Y | A | 0.3549 | |
| 372 | S | A | 0.0000 | |
| 373 | T | A | -0.0669 | |
| 374 | Y | A | 0.0000 | |
| 375 | F | A | 0.2772 | |
| 376 | N | A | 0.0000 | |
| 377 | K | A | -0.7207 | |
| 378 | D | A | -1.0079 | |
| 379 | E | A | -1.9167 | |
| 380 | T | A | 0.0000 | |
| 381 | A | A | 0.0000 | |
| 382 | Y | A | 1.1751 | |
| 383 | A | A | 0.0000 | |
| 384 | A | A | 0.0349 | |
| 385 | Y | A | 0.0000 | |
| 386 | M | A | 0.0000 | |
| 387 | Q | A | -0.4257 | |
| 388 | F | A | 0.1929 | |
| 389 | D | A | -0.6458 | |
| 390 | R | A | -2.0253 | |
| 391 | G | A | -0.5626 | |
| 392 | F | A | 1.1941 | |
| 393 | V | A | 0.0000 | |
| 394 | S | A | -0.2098 | |
| 395 | A | A | 0.2229 | |
| 396 | Y | A | 1.3722 | |
| 397 | M | A | 0.8629 | |
| 398 | V | A | 1.8238 | |
| 399 | T | A | 0.1949 | |
| 400 | D | A | -0.6778 | |
| 401 | V | A | 0.0000 | |
| 402 | D | A | 0.0000 | |
| 403 | K | A | -0.4920 | |
| 404 | M | A | -0.1982 | |
| 405 | E | A | -1.4992 | |
| 406 | A | A | 0.0000 | |
| 407 | A | A | 0.0365 | |
| 408 | A | A | -0.1770 | |
| 409 | K | A | -0.3844 | |
| 410 | G | A | 0.0000 | |
| 411 | V | A | 1.1383 | |
| 412 | F | A | 0.3767 | |
| 413 | K | A | -1.8620 | |
| 414 | G | A | 0.0000 | |
| 415 | P | A | -0.5103 | |
| 416 | D | A | -1.4916 | |
| 417 | G | A | -0.1794 | |
| 418 | F | A | 1.5463 | |
| 419 | E | A | -1.5919 | |
| 420 | Y | A | 0.6069 | |
| 421 | F | A | 2.1572 | |
| 422 | A | A | 0.3315 | |
| 423 | P | A | -0.2528 | |
| 424 | A | A | 0.0000 | |
| 425 | N | A | -1.2757 | |
| 426 | T | A | -0.3844 | |
| 427 | Q | A | -0.6315 | |
| 428 | N | A | -0.5331 | |
| 429 | N | A | -0.2588 | |
| 430 | N | A | -0.1995 | |
| 431 | I | A | 0.0742 | |
| 432 | E | A | -0.5858 | |
| 433 | G | A | 0.0000 | |
| 434 | Q | A | -0.5372 | |
| 435 | A | A | 0.0000 | |
| 436 | I | A | 2.2851 | |
| 437 | V | A | 2.0073 | |
| 438 | Y | A | 0.8215 | |
| 439 | Q | A | -1.0840 | |
| 440 | S | A | -0.7162 | |
| 441 | K | A | -1.4286 | |
| 442 | F | A | 1.4366 | |
| 443 | L | A | 1.0247 | |
| 444 | T | A | 0.1023 | |
| 445 | L | A | -0.0499 | |
| 446 | N | A | -1.2341 | |
| 447 | G | A | 0.0000 | |
| 448 | K | A | -0.7987 | |
| 449 | K | A | 0.0000 | |
| 450 | Y | A | 0.3091 | |
| 451 | Y | A | 0.5923 | |
| 452 | F | A | 0.0000 | |
| 453 | D | A | -1.9398 | |
| 454 | N | A | -1.4754 | |
| 455 | D | A | -1.9795 | |
| 456 | S | A | -0.7956 | |
| 457 | K | A | -1.3687 | |
| 458 | A | A | 0.0107 | |
| 459 | V | A | 1.3332 | |
| 460 | T | A | 0.0000 | |
| 461 | G | A | 0.0000 | |
| 462 | V | A | 0.0000 | |
| 463 | F | A | 0.9732 | |
| 464 | K | A | -1.4398 | |
| 465 | G | A | -0.5029 | |
| 466 | P | A | -0.5122 | |
| 467 | N | A | -1.3974 | |
| 468 | G | A | -0.6090 | |
| 469 | F | A | -0.1486 | |
| 470 | E | A | -0.1953 | |
| 471 | Y | A | 0.2129 | |
| 472 | F | A | 0.0000 | |
| 473 | A | A | -0.0136 | |
| 474 | P | A | -0.1208 | |
| 475 | A | A | -0.2474 | |
| 476 | N | A | -1.2725 | |
| 477 | T | A | -0.5884 | |
| 478 | D | A | -1.7850 | |
| 479 | A | A | -0.3543 | |
| 480 | N | A | -0.3218 | |
| 481 | N | A | -0.9619 | |
| 482 | I | A | 0.0000 | |
| 483 | E | A | -1.9528 | |
| 484 | G | A | 0.0000 | |
| 485 | Q | A | -0.4243 | |
| 486 | A | A | 0.0000 | |
| 487 | I | A | 0.0000 | |
| 488 | L | A | 0.2194 | |
| 489 | Y | A | 0.0000 | |
| 490 | Q | A | 0.0000 | |
| 491 | N | A | 0.0000 | |
| 492 | E | A | -0.5139 | |
| 493 | F | A | 1.1591 | |
| 494 | L | A | 0.8851 | |
| 495 | T | A | 0.1316 | |
| 496 | L | A | 0.2622 | |
| 497 | N | A | -1.1902 | |
| 498 | G | A | -0.2717 | |
| 499 | K | A | -0.4073 | |
| 500 | K | A | -0.2572 | |
| 501 | Y | A | 0.1321 | |
| 502 | Y | A | 0.0000 | |
| 503 | F | A | 0.0383 | |
| 504 | G | A | 0.0000 | |
| 505 | S | A | 0.0457 | |
| 506 | D | A | 0.0000 | |
| 507 | S | A | -0.3424 | |
| 508 | K | A | -1.1221 | |
| 509 | A | A | -0.0248 | |
| 510 | V | A | 0.5856 | |
| 511 | T | A | 0.0303 | |
| 512 | G | A | 0.0181 | |
| 513 | V | A | 0.5852 | |
| 514 | F | A | 0.0000 | |
| 515 | K | A | -1.1519 | |
| 516 | G | A | 0.0000 | |
| 517 | P | A | 0.0000 | |
| 518 | N | A | 0.0000 | |
| 519 | G | A | 0.0000 | |
| 520 | F | A | 0.2733 | |
| 521 | E | A | 0.0000 | |
| 522 | Y | A | 0.7767 | |
| 523 | F | A | 1.5556 | |
| 524 | A | A | 0.2417 | |
| 525 | P | A | -0.2486 | |
| 526 | A | A | -0.0152 | |
| 527 | N | A | 0.0000 | |
| 528 | T | A | -0.2337 | |
| 529 | H | A | -1.0227 | |
| 530 | N | A | -0.3279 | |
| 531 | N | A | 0.0000 | |
| 532 | N | A | -1.3285 | |
| 533 | I | A | -0.2541 | |
| 534 | E | A | -1.3479 | |
| 535 | G | A | -0.5434 | |
| 536 | Q | A | -1.2463 | |
| 537 | A | A | 0.0000 | |
| 538 | I | A | 1.3475 | |
| 539 | L | A | 0.0000 | |
| 540 | Y | A | 0.9557 | |
| 541 | Q | A | -0.1667 | |
| 542 | N | A | -0.6530 | |
| 543 | K | A | -0.6058 | |
| 544 | F | A | 0.0000 | |
| 545 | L | A | 0.7545 | |
| 546 | T | A | 0.2656 | |
| 547 | L | A | 0.5473 | |
| 548 | N | A | -1.2138 | |
| 549 | G | A | -1.0207 | |
| 550 | K | A | -1.9496 | |
| 551 | K | A | -1.0573 | |
| 552 | Y | A | 0.5260 | |
| 553 | Y | A | 0.3978 | |
| 554 | F | A | 0.2772 | |
| 555 | G | A | -0.4449 | |
| 556 | S | A | -0.6302 | |
| 557 | D | A | -1.8689 | |
| 558 | S | A | -0.8641 | |
| 559 | K | A | -1.7351 | |
| 560 | A | A | -0.2605 | |
| 561 | V | A | 0.1777 | |
| 562 | T | A | -0.0516 | |
| 563 | G | A | 0.0066 | |
| 564 | V | A | 0.8093 | |
| 565 | F | A | 0.7259 | |
| 566 | K | A | -1.5743 | |
| 567 | G | A | -0.8225 | |
| 568 | S | A | -0.3216 | |
| 569 | N | A | -0.1690 | |
| 570 | G | A | -0.0285 | |
| 571 | F | A | -0.0901 | |
| 572 | E | A | -0.5319 | |
| 573 | Y | A | 0.0163 | |
| 574 | F | A | 0.0000 | |
| 575 | A | A | 0.0000 | |
| 576 | P | A | -0.0497 | |
| 577 | A | A | -0.1376 | |
| 578 | N | A | -0.7351 | |
| 579 | T | A | 0.0000 | |
| 580 | D | A | -1.7787 | |
| 581 | A | A | -0.5062 | |
| 582 | N | A | -1.5059 | |
| 583 | N | A | -1.1432 | |
| 584 | I | A | 1.5199 | |
| 585 | E | A | -1.0307 | |
| 586 | G | A | -0.3851 | |
| 587 | Q | A | 0.0000 | |
| 588 | A | A | 0.0000 | |
| 589 | I | A | 0.0000 | |
| 590 | R | A | 0.0000 | |
| 591 | Y | A | 0.0000 | |
| 592 | Q | A | 0.0000 | |
| 593 | N | A | -0.7796 | |
| 594 | R | A | -1.7792 | |
| 595 | F | A | 0.4587 | |
| 596 | L | A | 0.0000 | |
| 597 | H | A | -0.1170 | |
| 598 | L | A | 0.0000 | |
| 599 | L | A | 1.4623 | |
| 600 | G | A | -0.4948 | |
| 601 | K | A | -1.5163 | |
| 602 | I | A | 1.1435 | |
| 603 | Y | A | 0.7726 | |
| 604 | Y | A | 1.3636 | |
| 605 | F | A | 0.0000 | |
| 606 | G | A | -0.2251 | |
| 607 | N | A | -0.6173 | |
| 608 | N | A | -0.4268 | |
| 609 | S | A | 0.0000 | |
| 610 | K | A | 0.0000 | |
| 611 | A | A | 0.3422 | |
| 612 | V | A | 1.7614 | |
| 613 | T | A | -0.0753 | |
| 614 | E | A | -1.8326 | |
| 615 | A | A | 0.0000 | |
| 616 | A | A | 0.0000 | |
| 617 | A | A | -0.2517 | |
| 618 | K | A | -1.4147 | |
| 619 | G | A | -0.4195 | |
| 620 | V | A | 0.4201 | |
| 621 | F | A | 1.0510 | |
| 622 | S | A | 0.0972 | |
| 623 | T | A | -0.3677 | |
| 624 | E | A | -2.1516 | |
| 625 | D | A | -2.1233 | |
| 626 | G | A | 0.0000 | |
| 627 | F | A | 0.0000 | |
| 628 | K | A | -0.2259 | |
| 629 | Y | A | 0.1301 | |
| 630 | F | A | 0.3071 | |
| 631 | A | A | 0.0000 | |
| 632 | P | A | -0.1039 | |
| 633 | A | A | -0.0606 | |
| 634 | N | A | -1.4897 | |
| 635 | T | A | 0.0081 | |
| 636 | L | A | 1.2072 | |
| 637 | D | A | -1.8437 | |
| 638 | E | A | -2.3072 | |
| 639 | N | A | 0.0000 | |
| 640 | L | A | 1.3398 | |
| 641 | E | A | -0.3093 | |
| 642 | G | A | -0.7777 | |
| 643 | E | A | -1.0839 | |
| 644 | A | A | -0.1424 | |
| 645 | I | A | 0.0000 | |
| 646 | D | A | -1.7530 | |
| 647 | F | A | -0.1463 | |
| 648 | T | A | -0.0197 | |
| 649 | G | A | -0.2054 | |
| 650 | K | A | -0.5517 | |
| 651 | L | A | 0.1704 | |
| 652 | I | A | 0.7040 | |
| 653 | I | A | 0.2697 | |
| 654 | D | A | -1.3374 | |
| 655 | E | A | -2.1415 | |
| 656 | N | A | -1.0169 | |
| 657 | I | A | 0.0000 | |
| 658 | Y | A | 0.0000 | |
| 659 | Y | A | 0.1519 | |
| 660 | F | A | 0.0000 | |
| 661 | D | A | -0.5499 | |
| 662 | D | A | -2.0613 | |
| 663 | N | A | -1.4287 | |
| 664 | Y | A | 0.6557 | |
| 665 | R | A | -0.1683 | |
| 666 | G | A | 0.0000 | |
| 667 | A | A | 0.0000 | |
| 668 | V | A | 0.4504 | |
| 669 | G | A | 0.0555 | |
| 670 | V | A | 0.5279 | |
| 671 | F | A | 0.6620 | |
| 672 | N | A | -1.1191 | |
| 673 | T | A | 0.0000 | |
| 674 | E | A | -2.1460 | |
| 675 | D | A | -2.1378 | |
| 676 | G | A | -0.2970 | |
| 677 | F | A | 0.5585 | |
| 678 | K | A | 0.0070 | |
| 679 | Y | A | 1.5092 | |
| 680 | F | A | 2.1661 | |
| 681 | A | A | 0.1867 | |
| 682 | H | A | -1.1738 | |
| 683 | H | A | -1.1751 | |
| 684 | N | A | 0.0000 | |
| 685 | E | A | -0.6190 | |
| 686 | D | A | 0.0000 | |
| 687 | L | A | 0.2228 | |
| 688 | G | A | 0.0000 | |
| 689 | N | A | 0.0000 | |
| 690 | E | A | -1.5243 | |
| 691 | E | A | -2.1250 | |
| 692 | G | A | -1.1415 | |
| 693 | E | A | -1.9077 | |
| 694 | E | A | 0.0000 | |
| 695 | I | A | 0.3899 | |
| 696 | S | A | 0.0000 | |
| 697 | Y | A | 0.0000 | |
| 698 | S | A | -0.1574 | |
| 699 | G | A | -0.1418 | |
| 700 | I | A | 0.5285 | |
| 701 | L | A | 0.2140 | |
| 702 | N | A | -1.1276 | |
| 703 | F | A | -0.0721 | |
| 704 | N | A | -1.4353 | |
| 705 | N | A | -1.5834 | |
| 706 | K | A | -0.6407 | |
| 707 | I | A | 0.0000 | |
| 708 | Y | A | 0.0000 | |
| 709 | Y | A | 0.3179 | |
| 710 | F | A | 0.0000 | |
| 711 | D | A | -1.2135 | |
| 712 | D | A | -1.9502 | |
| 713 | S | A | 0.0000 | |
| 714 | F | A | 0.0000 | |
| 715 | T | A | 0.0000 | |
| 716 | A | A | 0.0000 | |
| 717 | V | A | 0.0000 | |
| 718 | V | A | 0.2121 | |
| 719 | G | A | 0.2676 | |
| 720 | V | A | 1.5675 | |
| 721 | F | A | 0.0000 | |
| 722 | D | A | -0.8735 | |
| 723 | T | A | -0.2481 | |
| 724 | S | A | -0.5426 | |
| 725 | D | A | -1.8854 | |
| 726 | G | A | -0.3926 | |
| 727 | Y | A | 1.0598 | |
| 728 | K | A | 0.1524 | |
| 729 | Y | A | 0.7578 | |
| 730 | F | A | 0.4024 | |
| 731 | A | A | 0.0000 | |
| 732 | P | A | 0.0000 | |
| 733 | A | A | -0.2239 | |
| 734 | N | A | -1.2759 | |
| 735 | T | A | 0.0547 | |
| 736 | V | A | 1.7229 | |
| 737 | N | A | -0.2514 | |
| 738 | D | A | -2.0674 | |
| 739 | N | A | -1.4204 | |
| 740 | I | A | 1.1373 | |
| 741 | Y | A | 1.4357 | |
| 742 | G | A | -0.4452 | |
| 743 | Q | A | -1.2846 | |
| 744 | A | A | 0.0000 | |
| 745 | V | A | 0.0000 | |
| 746 | E | A | -0.3846 | |
| 747 | Y | A | 0.0000 | |
| 748 | S | A | -0.0729 | |
| 749 | G | A | -0.0130 | |
| 750 | L | A | 0.6383 | |
| 751 | V | A | 0.0000 | |
| 752 | R | A | -1.7507 | |
| 753 | V | A | -0.2118 | |
| 754 | G | A | -0.7623 | |
| 755 | E | A | -2.0669 | |
| 756 | D | A | -1.1257 | |
| 757 | V | A | 0.0976 | |
| 758 | Y | A | 0.0000 | |
| 759 | Y | A | 0.0000 | |
| 760 | F | A | 0.0000 | |
| 761 | G | A | -0.3775 | |
| 762 | E | A | -1.8411 | |
| 763 | T | A | -0.4010 | |
| 764 | Y | A | 0.0000 | |
| 765 | T | A | 0.0826 | |
| 766 | I | A | 0.7714 | |
| 767 | E | A | -0.1590 | |
| 768 | T | A | -0.1225 | |
| 769 | G | A | 0.0000 | |
| 770 | W | A | 0.2803 | |
| 771 | I | A | 0.0000 | |
| 772 | G | A | 0.1014 | |
| 773 | V | A | 1.2033 | |
| 774 | F | A | 2.0389 | |
| 775 | N | A | 0.0564 | |
| 776 | T | A | 0.0000 | |
| 777 | P | A | -0.5833 | |
| 778 | D | A | -1.8455 | |
| 779 | G | A | -0.2454 | |
| 780 | F | A | 0.2270 | |
| 781 | K | A | -0.2477 | |
| 782 | Y | A | 0.0000 | |
| 783 | F | A | 0.0000 | |
| 784 | A | A | 0.0000 | |
| 785 | H | A | -0.8657 | |
| 786 | Q | A | -1.6192 | |
| 787 | N | A | -1.1252 | |
| 788 | T | A | 0.0459 | |
| 789 | L | A | 1.2030 | |
| 790 | D | A | -1.8434 | |
| 791 | E | A | -2.2021 | |
| 792 | N | A | -0.3206 | |
| 793 | F | A | 1.1935 | |
| 794 | E | A | -1.1565 | |
| 795 | G | A | 0.0000 | |
| 796 | E | A | -0.7683 | |
| 797 | S | A | -0.0391 | |
| 798 | I | A | 0.5800 | |
| 799 | N | A | -1.0679 | |
| 800 | Y | A | 0.0096 | |
| 801 | T | A | -0.0423 | |
| 802 | G | A | 0.1023 | |
| 803 | W | A | 1.2709 | |
| 804 | L | A | 0.0000 | |
| 805 | D | A | -1.9696 | |
| 806 | L | A | -0.4826 | |
| 807 | D | A | -2.0863 | |
| 808 | E | A | -2.3782 | |
| 809 | K | A | -1.9506 | |
| 810 | R | A | -2.2646 | |
| 811 | Y | A | -0.0390 | |
| 812 | Y | A | 0.9936 | |
| 813 | F | A | 0.0000 | |
| 814 | T | A | -0.3480 | |
| 815 | D | A | -2.1238 | |
| 816 | E | A | -2.0179 | |
| 817 | Y | A | 0.4344 | |
| 818 | I | A | 0.4219 | |
| 819 | A | A | 0.0000 | |
| 820 | A | A | 0.0323 | |
| 821 | T | A | -0.2466 | |
| 822 | H | A | -1.1880 | |
| 823 | H | A | -1.3612 | |
| 824 | H | A | -1.3626 | |
| 825 | H | A | -1.3608 | |
| 826 | H | A | -1.3601 | |
| 827 | H | A | -1.1755 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine