Project name: ltbhoma

Chain sequence(s)	H: APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN; E: APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN; D: APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN; G: APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN; F: APQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0532
• Maximal score value: 0.2963
• Average score: -0.8564
• Total score value: -440.1669

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	D	-0.5818
2	P	D	0.0000
3	Q	D	-1.1286
4	T	D	-0.9846
5	I	D	0.0000
6	T	D	-1.2231
7	E	D	-2.2491
8	L	D	0.0000
9	C	D	0.0000
10	S	D	-1.7865
11	E	D	-1.7880
12	Y	D	-1.7700
13	R	D	-2.8853
14	N	D	-2.8236
15	T	D	-1.8859
16	Q	D	-1.0533
17	I	D	0.1634
18	Y	D	0.0818
19	T	D	-0.2252
20	I	D	-0.8385
21	N	D	-1.7143
22	D	D	-2.3936
23	K	D	-2.9095
24	I	D	0.0000
25	L	D	-1.9414
26	S	D	-1.2649
27	Y	D	0.0000
28	T	D	0.0000
29	E	D	0.0000
30	S	D	0.0000
31	M	D	0.0000
32	A	D	0.0000
33	G	D	-1.3533
34	K	D	-1.9769
35	R	D	-1.3163
36	E	D	0.0000
37	M	D	0.0000
38	V	D	0.0000
39	I	D	0.0000
40	I	D	0.0000
41	T	D	-1.1265
42	F	D	0.0000
43	K	D	-2.4563
44	S	D	-1.5336
45	G	D	-1.5113
46	E	D	-1.4355
47	T	D	-0.9206
48	F	D	0.0000
49	Q	D	0.0000
50	V	D	0.0000
51	E	D	0.0000
52	V	D	-0.3088
53	P	D	-0.8191
54	G	D	-0.8076
55	S	D	-0.9161
56	Q	D	-1.3449
57	H	D	0.0000
58	I	D	-0.9625
59	D	D	-2.3779
60	S	D	-1.8595
61	Q	D	0.0000
62	K	D	-2.4040
63	K	D	-2.6438
64	A	D	-1.6406
65	I	D	0.0000
66	E	D	-1.3608
67	R	D	0.0000
68	M	D	0.0000
69	K	D	0.0000
70	D	D	-0.7255
71	T	D	0.0000
72	L	D	0.0000
73	R	D	-0.2135
74	I	D	0.1691
75	T	D	0.0000
76	Y	D	0.0000
77	L	D	-0.7825
78	T	D	-0.9395
79	E	D	-2.4871
80	T	D	-2.0424
81	K	D	-2.7449
82	I	D	0.0000
83	D	D	0.0000
84	K	D	-0.6506
85	L	D	0.0000
86	C	D	0.0000
87	V	D	0.0000
88	W	D	-1.5065
89	N	D	-2.1068
90	N	D	-2.3591
91	K	D	-1.5054
92	T	D	-0.8463
93	P	D	0.0000
94	N	D	-1.0798
95	S	D	0.0000
96	I	D	0.0000
97	A	D	0.0000
98	A	D	0.0000
99	I	D	0.0000
100	S	D	0.0000
101	M	D	0.0000
102	K	D	-1.9033
103	N	D	-2.1757
1	A	E	-0.4724
2	P	E	0.0000
3	Q	E	-1.0113
4	T	E	-0.8119
5	I	E	0.0000
6	T	E	-0.9708
7	E	E	-1.7833
8	L	E	0.0000
9	C	E	0.0000
10	S	E	-1.5873
11	E	E	-1.8383
12	Y	E	-1.7210
13	R	E	-2.8879
14	N	E	-2.9681
15	T	E	-1.8271
16	Q	E	-0.9130
17	I	E	0.2507
18	Y	E	0.0905
19	T	E	-0.3242
20	I	E	-1.0937
21	N	E	-2.0660
22	D	E	-2.2609
23	K	E	-2.4610
24	I	E	0.0000
25	L	E	-1.4393
26	S	E	-0.9534
27	Y	E	0.0000
28	T	E	0.0000
29	E	E	0.0000
30	S	E	0.0000
31	M	E	0.0000
32	A	E	0.0000
33	G	E	-1.3266
34	K	E	-2.0222
35	R	E	-1.3941
36	E	E	0.0000
37	M	E	0.0000
38	V	E	0.0000
39	I	E	0.0000
40	I	E	0.0000
41	T	E	-0.8985
42	F	E	0.0000
43	K	E	-2.0953
44	S	E	-1.3819
45	G	E	-1.3734
46	E	E	-1.1077
47	T	E	-0.7727
48	F	E	0.0000
49	Q	E	0.0000
50	V	E	0.0000
51	E	E	-0.4653
52	V	E	-0.4622
53	P	E	-0.8530
54	G	E	-0.9643
55	S	E	-0.9411
56	Q	E	-1.2435
57	H	E	-1.1508
58	I	E	-0.9987
59	D	E	-2.3566
60	S	E	-1.9464
61	Q	E	0.0000
62	K	E	-2.7595
63	K	E	-2.7994
64	A	E	-1.7368
65	I	E	0.0000
66	E	E	-1.5979
67	R	E	0.0000
68	M	E	0.0000
69	K	E	0.0000
70	D	E	-0.7116
71	T	E	0.0000
72	L	E	0.0000
73	R	E	-0.2187
74	I	E	0.1363
75	T	E	0.0000
76	Y	E	0.0000
77	L	E	-0.7664
78	T	E	-0.9334
79	E	E	-2.3687
80	T	E	-1.7602
81	K	E	-2.5188
82	I	E	0.0000
83	D	E	-1.6990
84	K	E	-0.8058
85	L	E	0.0000
86	C	E	0.0000
87	V	E	0.0000
88	W	E	-1.5748
89	N	E	-2.2917
90	N	E	-2.5842
91	K	E	-1.9642
92	T	E	-1.0807
93	P	E	0.0000
94	N	E	-1.2586
95	S	E	0.0000
96	I	E	0.0000
97	A	E	0.0000
98	A	E	0.0000
99	I	E	0.0000
100	S	E	0.0000
101	M	E	0.0000
102	K	E	-2.0462
1	A	F	-0.5392
2	P	F	0.0000
3	Q	F	-1.0554
4	T	F	-0.8167
5	I	F	0.0000
6	T	F	-1.0462
7	E	F	-1.8647
8	L	F	0.0000
9	C	F	0.0000
10	S	F	-1.6616
11	E	F	-1.9323
12	Y	F	-1.7936
13	R	F	-2.7579
14	N	F	-2.8978
15	T	F	-1.8041
16	Q	F	-1.0312
17	I	F	0.1818
18	Y	F	-0.0352
19	T	F	-0.4040
20	I	F	-1.2503
21	N	F	-2.1595
22	D	F	-2.3492
23	K	F	-2.5870
24	I	F	0.0000
25	L	F	-1.1510
26	S	F	-0.8236
27	Y	F	0.0000
28	T	F	0.0000
29	E	F	0.0000
30	S	F	0.0000
31	M	F	0.0000
32	A	F	0.0000
33	G	F	-1.3404
34	K	F	-2.0128
35	R	F	-1.3502
36	E	F	0.0000
37	M	F	0.0000
38	V	F	0.0000
39	I	F	0.0000
40	I	F	0.0000
41	T	F	-1.0109
42	F	F	0.0000
43	K	F	-2.1411
44	S	F	-1.4475
45	G	F	-1.4568
46	E	F	-1.2901
47	T	F	-0.8579
48	F	F	0.0000
49	Q	F	0.0000
50	V	F	0.0000
51	E	F	-0.4033
52	V	F	-0.5082
53	P	F	-1.1355
54	G	F	-1.3504
55	S	F	-1.0242
56	Q	F	-1.2790
57	H	F	-1.1850
58	I	F	-0.9215
59	D	F	-2.3920
60	S	F	-1.9276
61	Q	F	0.0000
62	K	F	-2.9211
63	K	F	-2.8372
64	A	F	-1.7660
65	I	F	0.0000
66	E	F	-1.5042
67	R	F	0.0000
68	M	F	0.0000
69	K	F	0.0000
70	D	F	-0.7040
71	T	F	0.0000
72	L	F	0.0000
73	R	F	-0.1835
74	I	F	0.2045
75	T	F	0.0000
76	Y	F	-0.7727
77	L	F	-0.4105
78	T	F	-0.9262
79	E	F	-2.2477
80	T	F	-2.0818
81	K	F	-2.9166
82	I	F	0.0000
83	D	F	-1.8822
84	K	F	-0.9121
85	L	F	0.0000
86	C	F	0.0000
87	V	F	0.0000
88	W	F	-1.5034
89	N	F	-2.2333
90	N	F	-2.3035
91	K	F	-1.6315
92	T	F	-0.9347
93	P	F	0.0000
94	N	F	-1.1887
95	S	F	0.0000
96	I	F	0.0000
97	A	F	0.0000
98	A	F	0.0000
99	I	F	0.0000
100	S	F	0.0000
101	M	F	0.0000
102	K	F	-2.2547
103	N	F	-2.5237
1	A	G	-0.4169
2	P	G	0.0000
3	Q	G	-0.9317
4	T	G	-0.7367
5	I	G	0.0000
6	T	G	-0.9131
7	E	G	-1.6428
8	L	G	0.0000
9	C	G	0.0000
10	S	G	-1.4783
11	E	G	-1.6282
12	Y	G	-1.6089
13	R	G	-2.8394
14	N	G	-2.9663
15	T	G	-1.8187
16	Q	G	-0.9504
17	I	G	0.1832
18	Y	G	0.0323
19	T	G	-0.3793
20	I	G	-1.1435
21	N	G	-2.2145
22	D	G	-2.4913
23	K	G	-2.5602
24	I	G	0.0000
25	L	G	-1.7561
26	S	G	-1.1431
27	Y	G	0.0000
28	T	G	0.0000
29	E	G	0.0000
30	S	G	0.0000
31	M	G	0.0000
32	A	G	0.0000
33	G	G	-1.3316
34	K	G	-1.9359
35	R	G	-1.3262
36	E	G	0.0000
37	M	G	0.0000
38	V	G	0.0000
39	I	G	0.0000
40	I	G	0.0000
41	T	G	-1.0275
42	F	G	0.0000
43	K	G	-2.3361
44	S	G	-1.4927
45	G	G	-1.4645
46	E	G	-1.3365
47	T	G	-0.8638
48	F	G	0.0000
49	Q	G	0.0000
50	V	G	0.0000
51	E	G	-0.2607
52	V	G	-0.2695
53	P	G	-0.8032
54	G	G	-0.7570
55	S	G	-0.9557
56	Q	G	-1.4467
57	H	G	-1.1813
58	I	G	-1.1370
59	D	G	-2.5651
60	S	G	-2.0276
61	Q	G	0.0000
62	K	G	-2.8967
63	K	G	-2.8502
64	A	G	-1.7851
65	I	G	0.0000
66	E	G	-1.5776
67	R	G	0.0000
68	M	G	0.0000
69	K	G	0.0000
70	D	G	-0.7598
71	T	G	0.0000
72	L	G	0.0000
73	R	G	-0.0708
74	I	G	0.1221
75	T	G	0.0000
76	Y	G	0.0000
77	L	G	-0.5837
78	T	G	-0.8856
79	E	G	-2.2920
80	T	G	-1.7732
81	K	G	-2.5641
82	I	G	0.0000
83	D	G	-1.7081
84	K	G	-0.7708
85	L	G	0.0000
86	C	G	0.0000
87	V	G	0.0000
88	W	G	-1.6132
89	N	G	-2.3290
90	N	G	-2.6397
91	K	G	-2.0566
92	T	G	-1.1266
93	P	G	0.0000
94	N	G	-1.2841
95	S	G	0.0000
96	I	G	0.0000
97	A	G	0.0000
98	A	G	0.0000
99	I	G	0.0000
100	S	G	0.0000
101	M	G	0.0000
102	K	G	-2.0217
103	N	G	-2.2846
1	A	H	-0.4266
2	P	H	0.0000
3	Q	H	-1.1093
4	T	H	-0.8388
5	I	H	0.0000
6	T	H	-1.0433
7	E	H	-1.9255
8	L	H	0.0000
9	C	H	0.0000
10	S	H	-1.7304
11	E	H	-2.2480
12	Y	H	-1.7147
13	R	H	-2.5438
14	N	H	-2.1008
15	T	H	-1.4055
16	Q	H	-0.6748
17	I	H	0.2963
18	Y	H	0.0943
19	T	H	-0.3456
20	I	H	-1.2060
21	N	H	-2.1405
22	D	H	-2.6197
23	K	H	-2.6261
24	I	H	0.0000
25	L	H	-1.4462
26	S	H	-0.8477
27	Y	H	0.0000
28	T	H	0.0000
29	E	H	0.0000
30	S	H	0.0000
31	M	H	0.0000
32	A	H	0.0000
33	G	H	-1.3758
34	K	H	-2.0428
35	R	H	-1.3164
36	E	H	0.0000
37	M	H	0.0000
38	V	H	0.0000
39	I	H	0.0000
40	I	H	0.0000
41	T	H	-0.9384
42	F	H	0.0000
43	K	H	-2.2227
44	S	H	-1.4812
45	G	H	-1.4214
46	E	H	-1.2599
47	T	H	-0.7997
48	F	H	0.0000
49	Q	H	0.0000
50	V	H	0.0000
51	E	H	0.0000
52	V	H	-0.2991
53	P	H	-1.0646
54	G	H	-1.1216
55	S	H	-1.0690
56	Q	H	-1.5275
57	H	H	-1.2409
58	I	H	-1.1751
59	D	H	-2.4250
60	S	H	-1.7640
61	Q	H	0.0000
62	K	H	-2.4208
63	K	H	-1.9485
64	A	H	-1.2997
65	I	H	0.0000
66	E	H	-1.2397
67	R	H	0.0000
68	M	H	0.0000
69	K	H	0.0000
70	D	H	-0.7391
71	T	H	0.0000
72	L	H	0.0000
73	R	H	-0.1910
74	I	H	0.1997
75	T	H	0.0000
76	Y	H	-0.7159
77	L	H	-0.5213
78	T	H	-0.8977
79	E	H	-2.2718
80	T	H	-2.1411
81	K	H	-3.0532
82	I	H	0.0000
83	D	H	-1.8402
84	K	H	-0.9240
85	L	H	0.0000
86	C	H	0.0000
87	V	H	0.0000
88	W	H	-1.2026
89	N	H	-1.8595
90	N	H	-2.1861
91	K	H	-1.4973
92	T	H	-0.8760
93	P	H	0.0000
94	N	H	-1.0774
95	S	H	0.0000
96	I	H	0.0000
97	A	H	0.0000
98	A	H	0.0000
99	I	H	0.0000
100	S	H	0.0000
101	M	H	0.0000
102	K	H	-2.4146
103	N	H	-2.6578