Project name: beacb18f69293a9

Chain sequence(s)	A: IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYRKGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQV
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.4082
• Maximal score value: 1.6502
• Average score: -0.9898
• Total score value: -234.5753

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
16	I	A	0.0000
17	V	A	0.0000
18	G	A	-1.6660
19	G	A	-1.1497
20	T	A	-0.4168
21	A	A	0.2273
22	S	A	0.0000
23	V	A	0.6140
24	R	A	-1.4908
25	G	A	-1.7871
26	E	A	-0.9882
27	W	A	0.0000
28	P	A	-1.5756
29	W	A	0.0000
30	Q	A	0.0000
31	V	A	0.0000
32	T	A	0.0000
33	L	A	0.0000
34	H	A	0.0000
35	T	A	0.0000
36	T	A	-1.0053
37	S	A	-0.7387
37A	P	A	-0.6529
37B	T	A	-0.7937
37C	Q	A	-1.2727
37D	R	A	-1.3507
38	H	A	-0.5847
39	L	A	-0.1065
40	C	A	0.0000
41	G	A	0.0000
42	G	A	0.0000
43	S	A	0.0000
44	I	A	0.0000
45	I	A	-0.0670
46	G	A	-0.5625
47	N	A	-1.3259
48	Q	A	-1.4214
51	W	A	-1.0009
52	I	A	0.0000
53	L	A	0.0000
54	T	A	0.0000
55	A	A	0.0000
56	A	A	0.0000
57	H	A	-0.0421
58	C	A	0.0000
59	F	A	0.0000
59A	Y	A	0.8694
59B	G	A	-0.1861
59C	V	A	-0.6203
60	E	A	-1.8934
61	S	A	-1.7935
62	P	A	-1.9925
63	K	A	-2.5150
64	I	A	0.0000
65	L	A	0.0000
66	R	A	-0.9429
67	V	A	0.0000
68	Y	A	0.0000
69	S	A	-0.1268
70	G	A	-0.7549
71	I	A	-0.4039
72	L	A	-0.4368
73	N	A	-0.8985
74	Q	A	-1.1550
75	S	A	-1.3219
76	E	A	-1.8573
77	I	A	-1.9007
78	K	A	-3.4623
79	E	A	-3.6187
80	D	A	-3.1775
81	T	A	-2.0814
81A	S	A	-0.8203
82	F	A	0.3244
83	F	A	-0.3803
84	G	A	-1.5256
85	V	A	0.0000
86	Q	A	-3.0154
87	E	A	-2.4677
88	I	A	-0.4430
89	I	A	-0.2678
90	I	A	-0.1427
91	H	A	-1.1078
92	D	A	-2.3825
93	Q	A	-2.2502
94	Y	A	-1.5755
95	K	A	-2.1715
96	M	A	-1.1110
97	A	A	0.0000
98	E	A	-2.2042
99	S	A	-1.7239
100	G	A	0.0000
101	Y	A	-0.8666
102	D	A	0.0000
103	I	A	0.0000
104	A	A	0.0000
105	L	A	0.0000
106	L	A	0.0000
107	K	A	-2.0555
108	L	A	0.0000
109	E	A	-2.6523
110	T	A	-1.3748
111	T	A	-1.0958
112	V	A	0.0000
113	N	A	-1.4543
114	Y	A	-1.1466
115	T	A	-1.5087
116	D	A	-2.5838
117	S	A	-2.0159
118	Q	A	-1.8112
119	R	A	-2.3257
121	P	A	-0.6831
122	I	A	0.0000
123	C	A	0.5865
124	L	A	0.3711
125	P	A	0.0000
126	S	A	-1.8312
127	K	A	-3.1470
128	G	A	-2.4633
129	D	A	-2.5642
130	R	A	-3.2682
131	N	A	-1.9553
132	V	A	-0.0094
132A	I	A	1.6502
133	Y	A	0.0000
134	T	A	0.0501
135	D	A	-0.5914
136	C	A	0.0000
137	W	A	-0.4281
138	V	A	0.0000
139	T	A	0.0000
140	G	A	0.0000
141	W	A	0.0000
142	G	A	0.0000
143	Y	A	-2.5603
144	R	A	-3.4960
145	K	A	-3.4140
146	L	A	-2.1732
147	R	A	-2.9510
148	D	A	-2.9815
149	K	A	-2.8543
151	I	A	-1.5576
152	Q	A	-1.2249
153	N	A	-1.2104
154	T	A	-0.5434
155	L	A	0.0000
156	Q	A	-0.4745
157	K	A	-0.4906
158	A	A	0.0000
159	K	A	-1.1326
160	I	A	0.0000
161	P	A	-0.3758
162	L	A	0.5905
163	V	A	-0.1018
164	T	A	-0.8909
165	N	A	-1.9760
166	E	A	-2.9603
167	E	A	-2.4689
168	C	A	0.0000
169	Q	A	-3.3276
170	K	A	-3.6748
171	R	A	-3.2419
172	Y	A	0.0000
173	R	A	-3.3263
173A	G	A	-2.3205
174	H	A	-2.8067
175	K	A	-2.8947
176	I	A	0.0000
177	T	A	-1.5431
178	H	A	-1.9717
179	K	A	-1.1434
180	M	A	0.0000
181	I	A	-0.1575
182	C	A	0.0000
183	A	A	0.0000
184	G	A	0.0000
184A	Y	A	-2.3034
185	R	A	-3.8096
186	K	A	-4.0377
187	G	A	-3.3357
188	G	A	-2.0369
188A	K	A	-2.0822
189	D	A	0.0000
190	A	A	-1.0145
191	C	A	0.0000
192	K	A	-2.5443
193	G	A	-1.1487
194	D	A	0.0000
195	S	A	-0.3560
196	G	A	0.0000
197	G	A	0.0000
198	P	A	0.0000
198A	L	A	0.0000
198B	S	A	0.0000
201	C	A	0.0000
202	K	A	-1.4398
202A	H	A	-1.8352
202B	N	A	-2.2018
202C	E	A	-2.2750
202D	V	A	-0.5311
203	W	A	-0.2626
204	H	A	-0.0247
209	L	A	0.0000
210	V	A	0.0000
211	G	A	0.0000
212	I	A	0.0000
213	T	A	0.0000
214	S	A	0.0000
215	W	A	-0.7012
216	G	A	-1.1990
217	E	A	-1.5743
218	G	A	-1.3006
219	C	A	-1.7943
220	A	A	-2.5656
221	Q	A	-3.2507
222	R	A	-4.4082
223	E	A	-4.1465
224	R	A	-3.1832
225	P	A	0.0000
226	G	A	0.0000
227	V	A	0.0000
228	Y	A	0.0000
229	T	A	0.0000
230	N	A	-0.7797
231	V	A	0.0000
232	V	A	0.0000
233	E	A	-1.6233
234	Y	A	0.0000
235	V	A	0.0000
236	D	A	-1.7161
237	W	A	-1.0808
238	I	A	0.0000
239	L	A	-0.2733
240	E	A	-2.0189
241	K	A	-1.6064
242	T	A	-0.8568
243	Q	A	-0.7413
244	V	A	1.0072