Project name: 15%_pro_2osl

Chain sequence(s)	A: QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6241
• Maximal score value: 1.7512
• Average score: -0.6479
• Total score value: -281.8172

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-0.9855
2	I	A	0.0784
3	V	A	1.1684
4	L	A	0.0000
5	S	A	-0.5540
6	Q	A	-0.7057
7	S	A	-0.4118
8	P	A	0.1751
9	A	A	0.3981
10	I	A	1.2370
11	L	A	0.4621
12	S	A	-0.4425
13	A	A	0.0000
14	S	A	-2.1615
15	P	A	-2.1814
16	G	A	-2.4173
17	E	A	-3.1170
18	K	A	-2.9499
19	V	A	-1.2986
20	T	A	-0.3526
21	M	A	0.0000
22	T	A	-0.6874
23	C	A	0.0000
24	R	A	-1.7246
25	A	A	0.0000
26	S	A	-0.1955
27	S	A	-0.4486
28	S	A	-0.6123
29	V	A	0.0000
30	S	A	-0.2094
31	Y	A	0.2293
32	I	A	0.0000
33	H	A	0.0000
34	W	A	0.0000
35	F	A	0.0000
36	Q	A	-0.6379
37	Q	A	-0.7098
38	K	A	0.0000
39	P	A	-0.8461
40	G	A	-0.5939
41	S	A	-0.6613
42	S	A	-0.4845
43	P	A	0.0000
44	K	A	-1.4662
45	P	A	0.0000
46	W	A	-0.4850
47	I	A	0.0000
48	Y	A	-0.0145
49	A	A	-0.1845
50	T	A	0.0000
51	S	A	-0.6693
52	N	A	-1.1012
53	L	A	-0.0183
54	A	A	0.0000
55	S	A	-0.6769
56	G	A	-0.2605
57	V	A	0.0000
58	P	A	0.6073
59	V	A	1.3360
60	R	A	-0.3874
61	F	A	0.0000
62	S	A	-0.1462
63	G	A	0.0000
64	S	A	-0.6418
65	G	A	-0.8262
66	S	A	-0.7455
67	G	A	-0.7384
68	T	A	-1.0060
69	S	A	-1.2169
70	Y	A	0.0000
71	S	A	-0.6111
72	L	A	0.0000
73	T	A	-0.6803
74	I	A	0.0000
75	S	A	-2.0450
76	R	A	-3.1183
77	V	A	0.0000
78	E	A	-2.3774
79	A	A	0.0000
80	E	A	-2.1187
81	D	A	0.0000
82	A	A	-1.5095
83	A	A	0.0000
84	T	A	-0.2733
85	Y	A	0.0000
86	Y	A	-0.1156
87	C	A	0.0000
88	Q	A	0.0000
89	Q	A	0.0000
90	W	A	-0.0284
91	T	A	-0.2520
92	S	A	-0.8950
93	N	A	-1.6445
94	P	A	-1.4781
95	P	A	0.0000
96	T	A	-0.0701
97	F	A	0.2906
98	G	A	0.0000
99	G	A	-0.7673
100	G	A	-0.3152
101	T	A	0.0000
102	K	A	-0.2253
103	L	A	0.0000
104	E	A	-1.1232
105	I	A	0.0000
106	K	A	-2.1028
107	R	A	-1.3054
108	T	A	-0.2580
109	V	A	0.0968
110	A	A	-0.1814
111	A	A	-0.1323
112	P	A	0.0000
113	S	A	-0.1349
114	V	A	0.0000
115	F	A	0.1024
116	I	A	0.0000
117	F	A	0.0000
118	P	A	-0.3318
119	P	A	0.0000
120	S	A	-1.1787
121	D	A	-2.3222
122	E	A	-1.7984
123	Q	A	0.0000
124	L	A	-1.4439
125	K	A	-1.7722
126	S	A	-1.2516
127	G	A	-1.0569
128	T	A	-0.8577
129	A	A	0.0000
130	S	A	0.0000
131	V	A	0.0000
132	V	A	0.0000
133	C	A	0.0000
134	L	A	0.0000
135	L	A	0.0000
136	N	A	0.0000
137	N	A	-0.8598
138	F	A	0.0000
139	Y	A	-1.2543
140	P	A	-1.8727
141	R	A	-2.9033
142	E	A	-3.2297
143	A	A	-2.3283
144	K	A	-2.4359
145	V	A	-1.0848
146	Q	A	-0.6625
147	W	A	0.0000
148	K	A	-0.6590
149	V	A	0.0000
150	D	A	-2.3634
151	N	A	-1.7579
152	A	A	-0.3456
153	L	A	0.6430
154	Q	A	-0.1171
155	S	A	-0.4898
156	G	A	-0.9648
157	N	A	-0.7769
158	S	A	-0.9748
159	Q	A	-2.0372
160	E	A	-2.1568
161	S	A	-1.0516
162	V	A	-0.7886
163	T	A	-0.9210
164	E	A	-1.9888
165	Q	A	0.0000
166	D	A	-2.3084
167	S	A	-2.3897
168	K	A	-2.8255
169	D	A	-2.1662
170	S	A	0.0000
171	T	A	0.0000
172	Y	A	0.0000
173	S	A	0.0000
174	L	A	0.0000
175	S	A	0.0000
176	S	A	0.0000
177	T	A	-0.2482
178	L	A	0.6299
179	T	A	0.2235
180	L	A	-0.1003
181	S	A	-1.0594
182	K	A	-1.9673
183	A	A	-1.6608
184	D	A	-2.2622
185	Y	A	0.0000
186	E	A	-3.6241
187	K	A	-3.5903
188	H	A	-3.0778
189	K	A	-3.4769
190	V	A	0.0000
191	Y	A	0.0000
192	A	A	0.0000
193	C	A	0.0000
194	E	A	-0.7120
195	V	A	0.0000
196	T	A	-1.2444
197	H	A	0.0000
198	Q	A	-1.7738
199	G	A	-0.4336
200	L	A	-0.2528
201	S	A	-0.4682
202	S	A	-0.4679
203	P	A	-0.6400
204	V	A	-0.0133
205	T	A	-0.3095
206	K	A	-0.3800
207	S	A	-0.4534
208	F	A	-1.0003
209	N	A	-1.9269
210	R	A	-2.4734
211	G	A	-2.2887
212	E	A	-2.4568
1	Q	A	-0.9966
2	V	A	-0.0334
3	Q	A	-1.2137
4	L	A	0.0000
5	Q	A	-1.9026
6	Q	A	-1.0984
7	P	A	-0.9416
8	G	A	-1.0503
9	A	A	-0.9753
10	E	A	-1.4840
11	L	A	-0.6358
12	V	A	0.0000
13	K	A	-1.8645
14	P	A	-1.2620
15	G	A	-1.1472
16	A	A	-0.9886
17	S	A	-1.2074
18	V	A	0.0000
19	K	A	-2.0486
20	M	A	0.0000
21	S	A	-0.8835
22	C	A	0.0000
23	K	A	-1.6392
24	A	A	0.0000
25	S	A	-0.8363
26	G	A	-0.5379
27	Y	A	-0.0650
28	T	A	-0.2584
29	F	A	0.0000
30	T	A	-0.6876
31	S	A	0.0478
32	Y	A	0.4713
33	N	A	-0.0816
34	M	A	0.0000
35	H	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	K	A	0.0000
39	Q	A	-0.6322
40	T	A	-1.1311
41	P	A	-0.9698
42	G	A	-1.5894
43	R	A	-2.3834
44	G	A	-1.3776
45	L	A	0.0000
46	E	A	-1.0520
47	W	A	0.0000
48	I	A	0.0000
49	G	A	0.0000
50	A	A	0.0000
51	I	A	0.0000
52	Y	A	-0.6268
53	P	A	0.0000
54	G	A	-1.4905
55	N	A	-2.0705
56	G	A	-2.1316
57	D	A	-2.3827
58	T	A	-1.1204
59	S	A	-0.8738
60	Y	A	-1.1741
61	N	A	0.0000
62	Q	A	-2.8338
63	K	A	-2.8922
64	F	A	0.0000
65	K	A	-2.8813
66	G	A	-1.9612
67	K	A	-1.6824
68	A	A	0.0000
69	T	A	-0.9122
70	L	A	0.0000
71	T	A	-0.6823
72	A	A	-1.3422
73	D	A	-1.9980
74	K	A	-2.4057
75	S	A	-1.3659
76	S	A	-1.2251
77	S	A	-1.3507
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.5849
81	M	A	0.0000
82	Q	A	-1.3248
83	L	A	0.0000
84	S	A	-0.9369
85	S	A	-0.9149
86	L	A	0.0000
87	T	A	-1.2049
88	S	A	-1.3412
89	E	A	-1.9343
90	D	A	0.0000
91	S	A	-0.6159
92	A	A	0.0000
93	V	A	0.4923
94	Y	A	0.0000
95	Y	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	S	A	0.0000
100	T	A	0.0000
101	Y	A	1.7512
102	Y	A	1.6233
103	G	A	0.3529
104	G	A	0.0210
105	D	A	0.4997
106	W	A	0.9694
107	Y	A	0.0000
108	F	A	0.0000
109	N	A	-0.3210
110	V	A	-0.2231
111	W	A	-0.3879
112	G	A	0.0000
113	A	A	-0.4398
114	G	A	-0.3015
115	T	A	0.0000
116	T	A	-0.1874
117	V	A	0.0000
118	T	A	-0.5476
119	V	A	-0.8221
120	S	A	-0.5070
121	A	A	-0.5819
122	A	A	-0.3874
123	S	A	-0.6331
124	T	A	-0.9486
125	K	A	-1.2548
126	G	A	-1.3779
127	P	A	-0.6332
128	S	A	-0.3672
129	V	A	0.0000
130	F	A	0.0000
131	P	A	0.0000
132	L	A	0.0000
133	A	A	-1.1596
134	P	A	0.0000
135	S	A	-1.2888
136	S	A	-1.1220
137	K	A	-1.1316
138	S	A	-0.6971
139	T	A	-0.6630
140	S	A	-0.6693
141	G	A	-0.7749
142	G	A	-0.7682
143	T	A	-0.5756
144	A	A	-0.3518
145	A	A	0.0000
146	L	A	0.0000
147	G	A	0.0000
148	C	A	0.0000
149	L	A	0.0000
150	V	A	0.0000
151	K	A	-0.1944
152	D	A	-0.5811
153	Y	A	0.0000
154	F	A	0.0000
155	P	A	0.0000
156	E	A	-0.5579
157	P	A	-0.7749
158	V	A	-0.4055
159	T	A	-0.3646
160	V	A	-0.1997
161	S	A	-0.3874
162	W	A	0.0000
163	N	A	-0.7047
164	S	A	-0.6598
165	G	A	-0.5310
166	A	A	-0.2661
167	L	A	0.0025
168	T	A	-0.1753
169	S	A	-0.1955
170	G	A	-0.1993
171	V	A	0.1909
172	H	A	-0.1057
173	T	A	-0.0016
174	F	A	0.0000
175	P	A	-0.4922
176	A	A	0.1836
177	V	A	0.4609
178	L	A	1.3369
179	Q	A	0.1492
180	S	A	-0.0909
181	S	A	-0.2538
182	G	A	0.0000
183	L	A	0.1246
184	Y	A	0.4186
185	S	A	0.2387
186	L	A	0.0000
187	S	A	-0.0592
188	S	A	0.0000
189	V	A	0.0000
190	V	A	0.0000
191	T	A	-0.1475
192	V	A	0.0000
193	P	A	-0.5099
194	S	A	-0.5593
195	S	A	-0.6079
196	S	A	0.0000
197	L	A	-0.7532
198	G	A	-1.0064
199	T	A	-0.8041
200	Q	A	-1.2030
201	T	A	-1.1308
202	Y	A	0.0000
203	I	A	-1.0876
204	C	A	0.0000
205	N	A	-1.4539
206	V	A	0.0000
207	N	A	-1.8908
208	H	A	0.0000
209	K	A	-2.8394
210	P	A	-1.7126
211	S	A	-1.8473
212	N	A	-2.5439
213	T	A	-2.0524
214	K	A	-2.6477
215	V	A	-1.4633
216	D	A	-2.4367
217	K	A	-1.8534
218	K	A	-2.1991
219	V	A	0.0000
220	E	A	-2.6673
221	P	A	-2.1097
222	K	A	-2.4513
223	S	A	-1.4641