Project name: 5hys:L
Status: done
submitted: 2019-03-21 13:17:17, status changed: 2019-03-21 13:28:46
Settings
Chain sequence(s)
|
L: DIQLTQSPSSLSASVGDRVTITCRASQSVDYDGDSYMNWYQQKPGKAPKLLIYAASYLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSHEDPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6267
-
Maximal score value
-
1.5504
-
Average score
-
-0.8715
-
Total score value
-
-189.114
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
L |
-2.8052 |
|
2 |
I |
L |
0.0000 |
|
3 |
Q |
L |
-1.8062 |
|
4 |
L |
L |
0.0000 |
|
5 |
T |
L |
-0.8482 |
|
6 |
Q |
L |
0.0000 |
|
7 |
S |
L |
-0.8085 |
|
8 |
P |
L |
-0.5894 |
|
9 |
S |
L |
-0.9763 |
|
10 |
S |
L |
-1.0898 |
|
11 |
L |
L |
-0.7732 |
|
12 |
S |
L |
-0.9929 |
|
13 |
A |
L |
-1.2123 |
|
14 |
S |
L |
-1.1375 |
|
15 |
V |
L |
-0.2905 |
|
16 |
G |
L |
-1.2454 |
|
17 |
D |
L |
-2.5099 |
|
18 |
R |
L |
-2.7349 |
|
19 |
V |
L |
0.0000 |
|
20 |
T |
L |
-0.6772 |
|
21 |
I |
L |
0.0000 |
|
22 |
T |
L |
-0.6762 |
|
23 |
C |
L |
0.0000 |
|
24 |
R |
L |
-1.9940 |
|
25 |
A |
L |
-1.7052 |
|
26 |
S |
L |
-1.8316 |
|
27 |
Q |
L |
-2.2451 |
|
28 |
S |
L |
-1.3594 |
|
29 |
V |
L |
0.0000 |
|
30 |
D |
L |
-1.4149 |
|
31 |
Y |
L |
-0.4587 |
|
32 |
D |
L |
-1.8078 |
|
33 |
G |
L |
-1.4784 |
|
34 |
D |
L |
-1.2815 |
|
35 |
S |
L |
0.0000 |
|
36 |
Y |
L |
-0.1250 |
|
37 |
M |
L |
0.0000 |
|
38 |
N |
L |
0.8527 |
|
39 |
W |
L |
0.0000 |
|
40 |
Y |
L |
0.0542 |
|
41 |
Q |
L |
0.0000 |
|
42 |
Q |
L |
-1.5396 |
|
43 |
K |
L |
-1.9725 |
|
44 |
P |
L |
-1.6795 |
|
45 |
G |
L |
-1.7010 |
|
46 |
K |
L |
-2.3869 |
|
47 |
A |
L |
-1.4416 |
|
48 |
P |
L |
-1.3478 |
|
49 |
K |
L |
-1.6790 |
|
50 |
L |
L |
-0.2317 |
|
51 |
L |
L |
0.0000 |
|
52 |
I |
L |
0.0000 |
|
53 |
Y |
L |
1.3136 |
|
54 |
A |
L |
0.5058 |
|
55 |
A |
L |
0.0000 |
|
56 |
S |
L |
0.3551 |
|
57 |
Y |
L |
1.2070 |
|
58 |
L |
L |
0.8057 |
|
59 |
E |
L |
-0.2470 |
|
60 |
S |
L |
-0.4823 |
|
61 |
G |
L |
-0.6905 |
|
62 |
V |
L |
0.0000 |
|
63 |
P |
L |
-0.4577 |
|
64 |
S |
L |
-0.5263 |
|
65 |
R |
L |
-0.8521 |
|
66 |
F |
L |
0.0000 |
|
67 |
S |
L |
-0.1664 |
|
68 |
G |
L |
0.0266 |
|
69 |
S |
L |
-0.5849 |
|
70 |
G |
L |
-1.0524 |
|
71 |
S |
L |
-1.3307 |
|
72 |
G |
L |
-1.2928 |
|
73 |
T |
L |
-1.6997 |
|
74 |
D |
L |
-1.9692 |
|
75 |
F |
L |
0.0000 |
|
76 |
T |
L |
-0.6894 |
|
77 |
L |
L |
0.0000 |
|
78 |
T |
L |
-0.6605 |
|
79 |
I |
L |
0.0000 |
|
80 |
S |
L |
-1.6584 |
|
81 |
S |
L |
-1.4827 |
|
82 |
L |
L |
0.0000 |
|
83 |
Q |
L |
-0.9484 |
|
84 |
P |
L |
-1.5937 |
|
85 |
E |
L |
-1.7868 |
|
86 |
D |
L |
0.0000 |
|
87 |
F |
L |
-1.5327 |
|
88 |
A |
L |
0.0000 |
|
89 |
T |
L |
-1.1445 |
|
90 |
Y |
L |
0.0000 |
|
91 |
Y |
L |
-0.0496 |
|
92 |
C |
L |
0.0000 |
|
93 |
Q |
L |
0.0000 |
|
94 |
Q |
L |
0.0000 |
|
95 |
S |
L |
-0.2284 |
|
96 |
H |
L |
-1.1747 |
|
97 |
E |
L |
-2.7261 |
|
98 |
D |
L |
-2.7224 |
|
99 |
P |
L |
-1.4568 |
|
100 |
Y |
L |
-0.0319 |
|
101 |
T |
L |
0.0841 |
|
102 |
F |
L |
1.3724 |
|
103 |
G |
L |
0.0000 |
|
104 |
Q |
L |
-1.1329 |
|
105 |
G |
L |
0.0000 |
|
106 |
T |
L |
0.0000 |
|
107 |
K |
L |
-2.1536 |
|
108 |
V |
L |
0.0000 |
|
109 |
E |
L |
-1.6390 |
|
110 |
I |
L |
0.0000 |
|
111 |
K |
L |
-1.1484 |
|
112 |
R |
L |
-0.7299 |
|
113 |
T |
L |
-0.0592 |
|
114 |
V |
L |
0.2801 |
|
115 |
A |
L |
-0.1684 |
|
116 |
A |
L |
-0.2189 |
|
117 |
P |
L |
0.0000 |
|
118 |
S |
L |
-0.0448 |
|
119 |
V |
L |
0.4057 |
|
120 |
F |
L |
1.3486 |
|
121 |
I |
L |
1.3600 |
|
122 |
F |
L |
1.5504 |
|
123 |
P |
L |
-0.1760 |
|
124 |
P |
L |
-0.7248 |
|
125 |
S |
L |
-1.7695 |
|
126 |
D |
L |
-3.1683 |
|
127 |
E |
L |
-3.3627 |
|
128 |
Q |
L |
-2.4411 |
|
129 |
L |
L |
-2.5351 |
|
130 |
K |
L |
-2.9585 |
|
131 |
S |
L |
-1.8721 |
|
132 |
G |
L |
-1.3803 |
|
133 |
T |
L |
-1.1792 |
|
134 |
A |
L |
0.0000 |
|
135 |
S |
L |
0.0273 |
|
136 |
V |
L |
0.0000 |
|
137 |
V |
L |
0.7578 |
|
138 |
C |
L |
0.0000 |
|
139 |
L |
L |
0.5929 |
|
140 |
L |
L |
0.0000 |
|
141 |
N |
L |
-0.5555 |
|
142 |
N |
L |
-1.3081 |
|
143 |
F |
L |
0.0000 |
|
144 |
Y |
L |
0.0000 |
|
145 |
P |
L |
-1.7692 |
|
146 |
R |
L |
-2.9746 |
|
147 |
E |
L |
-3.1737 |
|
148 |
A |
L |
-2.1447 |
|
149 |
K |
L |
-1.8455 |
|
150 |
V |
L |
-0.9712 |
|
151 |
Q |
L |
-0.5985 |
|
152 |
W |
L |
0.0000 |
|
153 |
K |
L |
-0.5441 |
|
154 |
V |
L |
0.0000 |
|
155 |
D |
L |
-1.7236 |
|
156 |
N |
L |
-1.4706 |
|
157 |
A |
L |
-0.2282 |
|
158 |
L |
L |
0.7152 |
|
159 |
Q |
L |
-0.2840 |
|
160 |
S |
L |
-0.8216 |
|
161 |
G |
L |
-1.3710 |
|
162 |
N |
L |
-1.7103 |
|
163 |
S |
L |
-1.7934 |
|
164 |
Q |
L |
-2.4778 |
|
165 |
E |
L |
-2.3257 |
|
166 |
S |
L |
-1.2823 |
|
167 |
V |
L |
-0.7105 |
|
168 |
T |
L |
-1.2690 |
|
169 |
E |
L |
-2.4246 |
|
170 |
Q |
L |
0.0000 |
|
171 |
D |
L |
-2.5758 |
|
172 |
S |
L |
-2.4295 |
|
173 |
K |
L |
-2.7219 |
|
174 |
D |
L |
-2.0921 |
|
175 |
S |
L |
0.0000 |
|
176 |
T |
L |
0.0000 |
|
177 |
Y |
L |
0.0000 |
|
178 |
S |
L |
-1.0331 |
|
179 |
L |
L |
0.0000 |
|
180 |
S |
L |
-0.4269 |
|
181 |
S |
L |
0.0000 |
|
182 |
T |
L |
-0.7186 |
|
183 |
L |
L |
0.0000 |
|
184 |
T |
L |
-0.6554 |
|
185 |
L |
L |
-0.8522 |
|
186 |
S |
L |
-1.3165 |
|
187 |
K |
L |
-2.3399 |
|
188 |
A |
L |
-1.9670 |
|
189 |
D |
L |
-2.5431 |
|
190 |
Y |
L |
0.0000 |
|
191 |
E |
L |
-3.5792 |
|
192 |
K |
L |
-3.6267 |
|
193 |
H |
L |
-3.1229 |
|
194 |
K |
L |
-3.5098 |
|
195 |
V |
L |
-1.7645 |
|
196 |
Y |
L |
0.0000 |
|
197 |
A |
L |
0.0000 |
|
198 |
C |
L |
0.0000 |
|
199 |
E |
L |
-0.8635 |
|
200 |
V |
L |
0.0000 |
|
201 |
T |
L |
-1.0289 |
|
202 |
H |
L |
0.0000 |
|
203 |
Q |
L |
-1.7185 |
|
204 |
G |
L |
-0.4639 |
|
205 |
L |
L |
-0.2404 |
|
206 |
S |
L |
-0.4484 |
|
207 |
S |
L |
-0.3922 |
|
208 |
P |
L |
-0.4734 |
|
209 |
V |
L |
-0.0501 |
|
210 |
T |
L |
-0.4035 |
|
211 |
K |
L |
-0.3506 |
|
212 |
S |
L |
-0.4344 |
|
213 |
F |
L |
-1.1196 |
|
214 |
N |
L |
-2.5163 |
|
215 |
R |
L |
-3.0965 |
|
216 |
G |
L |
-2.3973 |
|
217 |
E |
L |
-2.7224 |
|