| Chain sequence(s) |
A: NGTPQNITDLCAEYHNTQIHTLNDKIFSYTESLAGKREMAIITFKNGATFQVEVPGSQHIDSQKKAIERMKDTLRIAYLTEAKVEKLCVWNNKTPHAIAAISMANEAAAKKKEALAYECEARKLWEEAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEGPGPGGYLTAWAGPKLEKDIPYNLKSEAQGATGPGPGGSLNTCWSFSGMSTLEAYLKLKGYGTGPGPGLTGAQVISEELGYDLKEADLSMLGRASSVKVTKGPGPGVEEGIVAGGGTAFVSVIPAIGTLGPGPGKSMEKLSSGVRIKRAADDAAGLAISEGPGPGDVASEMVNLSKMNILVQASQSMLAQANQQPQGVLAAYSVTSGYAHYSTYFNKDETAYAAYMQFDRGFVSAYMVTDVDKMEAAAKGVFKGPDGFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGVFKGPNGFEYFAPANTDANNIEGQAILYQNEFLTLNGKKYYFGSDSKAVTGVFKGPNGFEYFAPANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIYYFGNNSKAVTEAAAKGVFSTEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFTAVVGVFDTSDGYKYFAPANTVNDNIYGQAVEYSGLVRVGEDVYYFGETYTIETGWIGVFNTPDGFKYFAHQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATHHHHHH |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
| Mutated residues | AA150C, GA197C |
| Energy difference between WT (input) and mutated protein (by FoldX) | 0.698426 kcal/mol
Changes in protein stability upon mutation are calculated using the FoldX forcefield. Computational prediction of protein stability is used with the intention of preventing the experimental characterization of proteins bearing mutations that significantly destabilize their structure. Mutations resulting in a predicted reduction in protein stability ≥ 1 kcal/mol are considered disruptive. |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | N | A | -1.5290 | |
| 2 | G | A | -1.4111 | |
| 3 | T | A | -1.0623 | |
| 4 | P | A | -1.4777 | |
| 5 | Q | A | -1.9048 | |
| 6 | N | A | -1.8062 | |
| 7 | I | A | 0.0000 | |
| 8 | T | A | -1.0455 | |
| 9 | D | A | -1.3543 | |
| 10 | L | A | -0.5070 | |
| 11 | C | A | 0.0000 | |
| 12 | A | A | -1.0859 | |
| 13 | E | A | -1.7837 | |
| 14 | Y | A | -0.8930 | |
| 15 | H | A | -1.9448 | |
| 16 | N | A | -2.3835 | |
| 17 | T | A | -1.6892 | |
| 18 | Q | A | -1.1009 | |
| 19 | I | A | -0.1512 | |
| 20 | H | A | -0.6254 | |
| 21 | T | A | -0.9436 | |
| 22 | L | A | -1.8846 | |
| 23 | N | A | -2.6410 | |
| 24 | D | A | -2.4825 | |
| 25 | K | A | -1.8687 | |
| 26 | I | A | 0.0000 | |
| 27 | F | A | 0.8933 | |
| 28 | S | A | 0.7582 | |
| 29 | Y | A | 0.6187 | |
| 30 | T | A | -0.2688 | |
| 31 | E | A | -0.9265 | |
| 32 | S | A | -0.9336 | |
| 33 | L | A | -0.7186 | |
| 34 | A | A | -1.1266 | |
| 35 | G | A | -1.7992 | |
| 36 | K | A | -2.7895 | |
| 37 | R | A | -2.8995 | |
| 38 | E | A | -1.6008 | |
| 39 | M | A | -0.9719 | |
| 40 | A | A | 0.0000 | |
| 41 | I | A | 0.0359 | |
| 42 | I | A | 0.0000 | |
| 43 | T | A | -0.1219 | |
| 44 | F | A | 0.0000 | |
| 45 | K | A | -2.0199 | |
| 46 | N | A | -2.0523 | |
| 47 | G | A | -1.3843 | |
| 48 | A | A | -1.0457 | |
| 49 | T | A | -0.5379 | |
| 50 | F | A | 0.0000 | |
| 51 | Q | A | -0.2092 | |
| 52 | V | A | 0.0000 | |
| 53 | E | A | -0.7308 | |
| 54 | V | A | -1.0345 | |
| 55 | P | A | -1.2379 | |
| 56 | G | A | -1.0174 | |
| 57 | S | A | -0.9068 | |
| 58 | Q | A | -1.3824 | |
| 59 | H | A | -0.9024 | |
| 60 | I | A | 0.0890 | |
| 61 | D | A | -1.9210 | |
| 62 | S | A | -1.8551 | |
| 63 | Q | A | -1.8593 | |
| 64 | K | A | -2.0904 | |
| 65 | K | A | -1.9456 | |
| 66 | A | A | 0.0000 | |
| 67 | I | A | 0.0000 | |
| 68 | E | A | -0.9491 | |
| 69 | R | A | -0.8198 | |
| 70 | M | A | 0.0000 | |
| 71 | K | A | 0.0000 | |
| 72 | D | A | -0.4085 | |
| 73 | T | A | 0.0000 | |
| 74 | L | A | 0.0000 | |
| 75 | R | A | -0.1038 | |
| 76 | I | A | 0.2924 | |
| 77 | A | A | 0.0000 | |
| 78 | Y | A | 0.3831 | |
| 79 | L | A | 0.6653 | |
| 80 | T | A | -0.4661 | |
| 81 | E | A | -1.3054 | |
| 82 | A | A | -1.6583 | |
| 83 | K | A | -3.0233 | |
| 84 | V | A | 0.0000 | |
| 85 | E | A | -2.6627 | |
| 86 | K | A | -1.4244 | |
| 87 | L | A | 0.0000 | |
| 88 | C | A | 0.0000 | |
| 89 | V | A | 0.0000 | |
| 90 | W | A | -1.3029 | |
| 91 | N | A | -2.4082 | |
| 92 | N | A | -2.5065 | |
| 93 | K | A | -2.0163 | |
| 94 | T | A | -1.0786 | |
| 95 | P | A | -0.7729 | |
| 96 | H | A | -1.0611 | |
| 97 | A | A | 0.0000 | |
| 98 | I | A | 0.0000 | |
| 99 | A | A | -0.0250 | |
| 100 | A | A | 0.0000 | |
| 101 | I | A | 0.0000 | |
| 102 | S | A | 0.0000 | |
| 103 | M | A | -0.9835 | |
| 104 | A | A | -0.9289 | |
| 105 | N | A | -1.8076 | |
| 106 | E | A | -1.3263 | |
| 107 | A | A | -1.0111 | |
| 108 | A | A | -1.1942 | |
| 109 | A | A | -1.8146 | |
| 110 | K | A | -2.5496 | |
| 111 | K | A | -2.4417 | |
| 112 | K | A | -1.9888 | |
| 113 | E | A | 0.0000 | |
| 114 | A | A | -0.7544 | |
| 115 | L | A | -0.5561 | |
| 116 | A | A | 0.0000 | |
| 117 | Y | A | -0.8212 | |
| 118 | E | A | -2.1892 | |
| 119 | C | A | -1.1477 | |
| 120 | E | A | -1.8980 | |
| 121 | A | A | 0.0000 | |
| 122 | R | A | -3.2251 | |
| 123 | K | A | -3.3413 | |
| 124 | L | A | -2.7045 | |
| 125 | W | A | -2.4768 | |
| 126 | E | A | -3.7040 | |
| 127 | E | A | -3.3958 | |
| 128 | A | A | 0.0000 | |
| 129 | E | A | -2.7986 | |
| 130 | K | A | -3.2712 | |
| 131 | Y | A | -1.5309 | |
| 132 | W | A | -1.6279 | |
| 133 | D | A | -2.4644 | |
| 134 | E | A | -1.8612 | |
| 135 | Y | A | -0.8494 | |
| 136 | S | A | -1.1369 | |
| 137 | K | A | -1.4696 | |
| 138 | Y | A | -0.0846 | |
| 139 | N | A | -0.5710 | |
| 140 | Y | A | -0.0323 | |
| 141 | K | A | -1.1368 | |
| 142 | G | A | 0.0000 | |
| 143 | I | A | -0.2044 | |
| 144 | E | A | -0.7684 | |
| 145 | Y | A | -0.1777 | |
| 146 | L | A | -0.8624 | |
| 147 | A | A | -0.3080 | |
| 148 | E | A | -0.1680 | |
| 149 | A | A | 0.0000 | |
| 150 | C | A | -0.8029 | mutated: AA150C |
| 151 | R | A | -0.6521 | |
| 152 | L | A | 0.0000 | |
| 153 | F | A | -1.1383 | |
| 154 | D | A | -2.1580 | |
| 155 | E | A | -0.9640 | |
| 156 | G | A | -0.7507 | |
| 157 | M | A | -0.5480 | |
| 158 | E | A | -1.1264 | |
| 159 | C | A | -0.8611 | |
| 160 | E | A | -1.9292 | |
| 161 | G | A | -1.2935 | |
| 162 | P | A | -0.7902 | |
| 163 | G | A | 0.0000 | |
| 164 | P | A | 0.1784 | |
| 165 | G | A | -0.1240 | |
| 166 | G | A | -0.0331 | |
| 167 | Y | A | -0.1721 | |
| 168 | L | A | -0.0641 | |
| 169 | T | A | -0.2801 | |
| 170 | A | A | -0.3354 | |
| 171 | W | A | 0.1240 | |
| 172 | A | A | -0.3880 | |
| 173 | G | A | 0.0000 | |
| 174 | P | A | -1.0441 | |
| 175 | K | A | -1.9427 | |
| 176 | L | A | -0.7965 | |
| 177 | E | A | 0.0000 | |
| 178 | K | A | -1.8377 | |
| 179 | D | A | -2.1593 | |
| 180 | I | A | -0.5674 | |
| 181 | P | A | 0.0000 | |
| 182 | Y | A | -0.5787 | |
| 183 | N | A | -1.4143 | |
| 184 | L | A | -0.6802 | |
| 185 | K | A | 0.0000 | |
| 186 | S | A | -1.3271 | |
| 187 | E | A | -2.2745 | |
| 188 | A | A | -1.6919 | |
| 189 | Q | A | -1.7877 | |
| 190 | G | A | -1.4899 | |
| 191 | A | A | -1.0189 | |
| 192 | T | A | -1.0417 | |
| 193 | G | A | -0.8461 | |
| 194 | P | A | -0.8308 | |
| 195 | G | A | -0.5559 | |
| 196 | P | A | -0.3197 | |
| 197 | C | A | -0.6785 | mutated: GA197C |
| 198 | G | A | -0.8491 | |
| 199 | S | A | 0.0000 | |
| 200 | L | A | -0.6748 | |
| 201 | N | A | -0.6425 | |
| 202 | T | A | -0.6196 | |
| 203 | C | A | 0.0000 | |
| 204 | W | A | 0.2037 | |
| 205 | S | A | 0.0000 | |
| 206 | F | A | 0.4440 | |
| 207 | S | A | 0.0115 | |
| 208 | G | A | 0.0000 | |
| 209 | M | A | 0.2057 | |
| 210 | S | A | 0.0418 | |
| 211 | T | A | 0.0000 | |
| 212 | L | A | 0.1449 | |
| 213 | E | A | 0.0000 | |
| 214 | A | A | 0.0000 | |
| 215 | Y | A | 0.0000 | |
| 216 | L | A | 0.0000 | |
| 217 | K | A | -0.9123 | |
| 218 | L | A | 0.0000 | |
| 219 | K | A | -1.6246 | |
| 220 | G | A | -0.9463 | |
| 221 | Y | A | -0.3791 | |
| 222 | G | A | -0.6741 | |
| 223 | T | A | -0.4267 | |
| 224 | G | A | 0.0000 | |
| 225 | P | A | 0.0000 | |
| 226 | G | A | 0.0000 | |
| 227 | P | A | 0.0000 | |
| 228 | G | A | 0.0000 | |
| 229 | L | A | 0.0000 | |
| 230 | T | A | -0.4464 | |
| 231 | G | A | -0.6352 | |
| 232 | A | A | -0.8424 | |
| 233 | Q | A | -1.1549 | |
| 234 | V | A | -0.5626 | |
| 235 | I | A | 0.0000 | |
| 236 | S | A | 0.1443 | |
| 237 | E | A | 0.0000 | |
| 238 | E | A | -0.9969 | |
| 239 | L | A | 0.0000 | |
| 240 | G | A | -1.1998 | |
| 241 | Y | A | -0.6541 | |
| 242 | D | A | -2.0241 | |
| 243 | L | A | -1.3860 | |
| 244 | K | A | -2.6927 | |
| 245 | E | A | -2.2468 | |
| 246 | A | A | -1.5312 | |
| 247 | D | A | -1.5069 | |
| 248 | L | A | 0.0113 | |
| 249 | S | A | 0.2056 | |
| 250 | M | A | 0.6539 | |
| 251 | L | A | 0.0770 | |
| 252 | G | A | -0.6366 | |
| 253 | R | A | -1.6798 | |
| 254 | A | A | -0.7524 | |
| 255 | S | A | -0.3361 | |
| 256 | S | A | -0.1548 | |
| 257 | V | A | 0.0000 | |
| 258 | K | A | -0.7028 | |
| 259 | V | A | 0.0000 | |
| 260 | T | A | -0.3011 | |
| 261 | K | A | 0.0000 | |
| 262 | G | A | 0.0000 | |
| 263 | P | A | -0.6067 | |
| 264 | G | A | -0.5284 | |
| 265 | P | A | -0.3164 | |
| 266 | G | A | 0.0000 | |
| 267 | V | A | 0.0000 | |
| 268 | E | A | -0.4610 | |
| 269 | E | A | -0.4538 | |
| 270 | G | A | 0.0000 | |
| 271 | I | A | 0.4621 | |
| 272 | V | A | 0.4974 | |
| 273 | A | A | 0.3314 | |
| 274 | G | A | -0.3006 | |
| 275 | G | A | -0.7388 | |
| 276 | G | A | -0.6468 | |
| 277 | T | A | 0.0000 | |
| 278 | A | A | 0.0000 | |
| 279 | F | A | 0.0000 | |
| 280 | V | A | 0.0162 | |
| 281 | S | A | 0.0000 | |
| 282 | V | A | 0.0000 | |
| 283 | I | A | 0.8159 | |
| 284 | P | A | 0.4730 | |
| 285 | A | A | 1.0327 | |
| 286 | I | A | 1.9709 | |
| 287 | G | A | 0.8953 | |
| 288 | T | A | 0.5014 | |
| 289 | L | A | 0.0000 | |
| 290 | G | A | 0.0000 | |
| 291 | P | A | 0.0000 | |
| 292 | G | A | 0.0000 | |
| 293 | P | A | -0.6870 | |
| 294 | G | A | 0.0000 | |
| 295 | K | A | -1.2351 | |
| 296 | S | A | 0.0000 | |
| 297 | M | A | -1.3181 | |
| 298 | E | A | -2.3410 | |
| 299 | K | A | -1.9605 | |
| 300 | L | A | 0.0000 | |
| 301 | S | A | -1.3314 | |
| 302 | S | A | -1.2348 | |
| 303 | G | A | -1.1469 | |
| 304 | V | A | -1.5522 | |
| 305 | R | A | -1.8375 | |
| 306 | I | A | -0.2861 | |
| 307 | K | A | -2.2052 | |
| 308 | R | A | -2.6093 | |
| 309 | A | A | -1.3713 | |
| 310 | A | A | -1.9040 | |
| 311 | D | A | -2.7067 | |
| 312 | D | A | -2.5149 | |
| 313 | A | A | -0.9173 | |
| 314 | A | A | -0.1077 | |
| 315 | G | A | -0.0308 | |
| 316 | L | A | 0.7734 | |
| 317 | A | A | 0.1025 | |
| 318 | I | A | 0.0000 | |
| 319 | S | A | -1.0361 | |
| 320 | E | A | -1.7434 | |
| 321 | G | A | -1.2429 | |
| 322 | P | A | -1.3283 | |
| 323 | G | A | -1.7060 | |
| 324 | P | A | -1.6078 | |
| 325 | G | A | -1.7154 | |
| 326 | D | A | -2.1371 | |
| 327 | V | A | 0.0000 | |
| 328 | A | A | -0.8465 | |
| 329 | S | A | -0.7971 | |
| 330 | E | A | -0.8574 | |
| 331 | M | A | 0.0000 | |
| 332 | V | A | 0.4951 | |
| 333 | N | A | 0.3117 | |
| 334 | L | A | 1.3710 | |
| 335 | S | A | 0.2372 | |
| 336 | K | A | -0.2059 | |
| 337 | M | A | 0.5965 | |
| 338 | N | A | -0.5213 | |
| 339 | I | A | 0.3768 | |
| 340 | L | A | 1.0954 | |
| 341 | V | A | 0.7329 | |
| 342 | Q | A | -0.5800 | |
| 343 | A | A | -0.9905 | |
| 344 | S | A | 0.0000 | |
| 345 | Q | A | -1.2491 | |
| 346 | S | A | -0.3511 | |
| 347 | M | A | 0.0820 | |
| 348 | L | A | 0.2264 | |
| 349 | A | A | 0.0000 | |
| 350 | Q | A | -0.1303 | |
| 351 | A | A | -0.2171 | |
| 352 | N | A | 0.0000 | |
| 353 | Q | A | -1.0153 | |
| 354 | Q | A | 0.0000 | |
| 355 | P | A | -0.6343 | |
| 356 | Q | A | -0.8536 | |
| 357 | G | A | -0.1044 | |
| 358 | V | A | 0.0161 | |
| 359 | L | A | 0.0000 | |
| 360 | A | A | 0.0000 | |
| 361 | A | A | 0.1924 | |
| 362 | Y | A | 0.5419 | |
| 363 | S | A | 0.5688 | |
| 364 | V | A | 0.6030 | |
| 365 | T | A | 0.2120 | |
| 366 | S | A | 0.0441 | |
| 367 | G | A | 0.0296 | |
| 368 | Y | A | 0.6744 | |
| 369 | A | A | 0.3410 | |
| 370 | H | A | -0.1364 | |
| 371 | Y | A | -0.1181 | |
| 372 | S | A | 0.0000 | |
| 373 | T | A | -0.1852 | |
| 374 | Y | A | 0.0000 | |
| 375 | F | A | 0.4276 | |
| 376 | N | A | 0.0000 | |
| 377 | K | A | -1.0028 | |
| 378 | D | A | -1.7249 | |
| 379 | E | A | -2.3559 | |
| 380 | T | A | 0.0000 | |
| 381 | A | A | 0.0000 | |
| 382 | Y | A | 1.0078 | |
| 383 | A | A | 0.0000 | |
| 384 | A | A | 0.2727 | |
| 385 | Y | A | 0.0000 | |
| 386 | M | A | 0.0000 | |
| 387 | Q | A | -0.8450 | |
| 388 | F | A | -0.7507 | |
| 389 | D | A | -1.3532 | |
| 390 | R | A | -1.9404 | |
| 391 | G | A | -0.9093 | |
| 392 | F | A | 0.5897 | |
| 393 | V | A | 0.0000 | |
| 394 | S | A | 0.5189 | |
| 395 | A | A | 1.2519 | |
| 396 | Y | A | 2.1941 | |
| 397 | M | A | 2.1764 | |
| 398 | V | A | 1.9334 | |
| 399 | T | A | 0.7969 | |
| 400 | D | A | -0.5488 | |
| 401 | V | A | 0.0000 | |
| 402 | D | A | 0.0000 | |
| 403 | K | A | -1.1351 | |
| 404 | M | A | -1.1333 | |
| 405 | E | A | -1.7147 | |
| 406 | A | A | 0.0000 | |
| 407 | A | A | 0.0187 | |
| 408 | A | A | -0.1963 | |
| 409 | K | A | -0.5412 | |
| 410 | G | A | 0.0000 | |
| 411 | V | A | 0.9248 | |
| 412 | F | A | 0.4863 | |
| 413 | K | A | -1.1283 | |
| 414 | G | A | 0.0000 | |
| 415 | P | A | -1.1168 | |
| 416 | D | A | -1.8217 | |
| 417 | G | A | -0.8827 | |
| 418 | F | A | 0.1185 | |
| 419 | E | A | -0.8075 | |
| 420 | Y | A | 1.0190 | |
| 421 | F | A | 1.9357 | |
| 422 | A | A | 0.7550 | |
| 423 | P | A | -0.4154 | |
| 424 | A | A | 0.0000 | |
| 425 | N | A | -2.0857 | |
| 426 | T | A | -1.4333 | |
| 427 | Q | A | -1.2185 | |
| 428 | N | A | -0.9158 | |
| 429 | N | A | -0.4432 | |
| 430 | N | A | -0.1857 | |
| 431 | I | A | -0.4626 | |
| 432 | E | A | -0.3794 | |
| 433 | G | A | 0.0000 | |
| 434 | Q | A | 0.2040 | |
| 435 | A | A | 0.0000 | |
| 436 | I | A | 1.9545 | |
| 437 | V | A | 1.9502 | |
| 438 | Y | A | 1.2947 | |
| 439 | Q | A | -0.3606 | |
| 440 | S | A | -0.8272 | |
| 441 | K | A | -1.3221 | |
| 442 | F | A | 0.6689 | |
| 443 | L | A | 0.7709 | |
| 444 | T | A | 0.1870 | |
| 445 | L | A | -0.5910 | |
| 446 | N | A | -1.7249 | |
| 447 | G | A | 0.0000 | |
| 448 | K | A | -1.2943 | |
| 449 | K | A | 0.0000 | |
| 450 | Y | A | -0.2857 | |
| 451 | Y | A | -0.7175 | |
| 452 | F | A | 0.0000 | |
| 453 | D | A | -2.5865 | |
| 454 | N | A | -2.9053 | |
| 455 | D | A | -2.8313 | |
| 456 | S | A | -1.8429 | |
| 457 | K | A | -2.0239 | |
| 458 | A | A | -0.7574 | |
| 459 | V | A | 0.4279 | |
| 460 | T | A | 0.0000 | |
| 461 | G | A | 0.0000 | |
| 462 | V | A | 0.0000 | |
| 463 | F | A | 0.1229 | |
| 464 | K | A | -1.5573 | |
| 465 | G | A | -1.3519 | |
| 466 | P | A | -1.4119 | |
| 467 | N | A | -1.9027 | |
| 468 | G | A | -1.3591 | |
| 469 | F | A | -0.9325 | |
| 470 | E | A | -0.8263 | |
| 471 | Y | A | 0.0753 | |
| 472 | F | A | 0.0000 | |
| 473 | A | A | -0.0636 | |
| 474 | P | A | 0.0149 | |
| 475 | A | A | -0.1794 | |
| 476 | N | A | -1.0398 | |
| 477 | T | A | -0.5482 | |
| 478 | D | A | -1.6868 | |
| 479 | A | A | -1.3059 | |
| 480 | N | A | -1.2762 | |
| 481 | N | A | -2.2430 | |
| 482 | I | A | 0.0000 | |
| 483 | E | A | -3.1223 | |
| 484 | G | A | 0.0000 | |
| 485 | Q | A | -1.4994 | |
| 486 | A | A | 0.0000 | |
| 487 | I | A | 0.0000 | |
| 488 | L | A | 0.3189 | |
| 489 | Y | A | 0.0000 | |
| 490 | Q | A | 0.0000 | |
| 491 | N | A | 0.0000 | |
| 492 | E | A | -0.2447 | |
| 493 | F | A | 1.1685 | |
| 494 | L | A | 1.1164 | |
| 495 | T | A | 0.3576 | |
| 496 | L | A | 0.0656 | |
| 497 | N | A | -0.8968 | |
| 498 | G | A | -0.0572 | |
| 499 | K | A | -0.0834 | |
| 500 | K | A | 0.0189 | |
| 501 | Y | A | 0.2186 | |
| 502 | Y | A | 0.0000 | |
| 503 | F | A | 0.1587 | |
| 504 | G | A | 0.0000 | |
| 505 | S | A | 0.1141 | |
| 506 | D | A | 0.0000 | |
| 507 | S | A | -0.4645 | |
| 508 | K | A | -1.0935 | |
| 509 | A | A | -0.2319 | |
| 510 | V | A | -0.0527 | |
| 511 | T | A | -0.2035 | |
| 512 | G | A | -0.2458 | |
| 513 | V | A | 0.3712 | |
| 514 | F | A | 0.0000 | |
| 515 | K | A | -0.6791 | |
| 516 | G | A | 0.0000 | |
| 517 | P | A | 0.0000 | |
| 518 | N | A | 0.0000 | |
| 519 | G | A | 0.0000 | |
| 520 | F | A | 0.6974 | |
| 521 | E | A | 0.0000 | |
| 522 | Y | A | 0.8700 | |
| 523 | F | A | 1.6051 | |
| 524 | A | A | 0.7053 | |
| 525 | P | A | -0.1199 | |
| 526 | A | A | -0.5893 | |
| 527 | N | A | 0.0000 | |
| 528 | T | A | -0.3510 | |
| 529 | H | A | -1.5447 | |
| 530 | N | A | -1.6485 | |
| 531 | N | A | 0.0000 | |
| 532 | N | A | -2.2505 | |
| 533 | I | A | -1.6800 | |
| 534 | E | A | -2.2071 | |
| 535 | G | A | -1.4081 | |
| 536 | Q | A | -1.6304 | |
| 537 | A | A | 0.0000 | |
| 538 | I | A | 0.8701 | |
| 539 | L | A | 0.0000 | |
| 540 | Y | A | 1.0079 | |
| 541 | Q | A | 0.3221 | |
| 542 | N | A | -0.2014 | |
| 543 | K | A | -0.0973 | |
| 544 | F | A | 0.0000 | |
| 545 | L | A | 0.4861 | |
| 546 | T | A | -0.2126 | |
| 547 | L | A | -0.4104 | |
| 548 | N | A | -1.6145 | |
| 549 | G | A | -1.9045 | |
| 550 | K | A | -2.4674 | |
| 551 | K | A | -1.5710 | |
| 552 | Y | A | -0.2795 | |
| 553 | Y | A | 0.0486 | |
| 554 | F | A | -0.2996 | |
| 555 | G | A | -1.1592 | |
| 556 | S | A | -1.6533 | |
| 557 | D | A | -2.4079 | |
| 558 | S | A | -2.0195 | |
| 559 | K | A | -2.0569 | |
| 560 | A | A | -0.8379 | |
| 561 | V | A | 0.1955 | |
| 562 | T | A | 0.0438 | |
| 563 | G | A | 0.4658 | |
| 564 | V | A | 0.8505 | |
| 565 | F | A | 0.1883 | |
| 566 | K | A | -1.4590 | |
| 567 | G | A | -1.5674 | |
| 568 | S | A | -1.4487 | |
| 569 | N | A | -1.4524 | |
| 570 | G | A | -0.7846 | |
| 571 | F | A | -0.3148 | |
| 572 | E | A | -0.6429 | |
| 573 | Y | A | -0.0859 | |
| 574 | F | A | 0.0000 | |
| 575 | A | A | 0.0000 | |
| 576 | P | A | -0.6232 | |
| 577 | A | A | -1.0323 | |
| 578 | N | A | -1.8621 | |
| 579 | T | A | 0.0000 | |
| 580 | D | A | -2.3534 | |
| 581 | A | A | -1.6558 | |
| 582 | N | A | -2.2581 | |
| 583 | N | A | -1.6723 | |
| 584 | I | A | 0.3168 | |
| 585 | E | A | -1.1207 | |
| 586 | G | A | -0.8848 | |
| 587 | Q | A | 0.0000 | |
| 588 | A | A | 0.0000 | |
| 589 | I | A | 0.0000 | |
| 590 | R | A | 0.0000 | |
| 591 | Y | A | 0.0000 | |
| 592 | Q | A | 0.0000 | |
| 593 | N | A | -0.6576 | |
| 594 | R | A | -1.3186 | |
| 595 | F | A | 0.2177 | |
| 596 | L | A | 0.0000 | |
| 597 | H | A | -0.5093 | |
| 598 | L | A | 0.0000 | |
| 599 | L | A | 1.0828 | |
| 600 | G | A | -0.4326 | |
| 601 | K | A | -0.7500 | |
| 602 | I | A | 1.0085 | |
| 603 | Y | A | 1.1753 | |
| 604 | Y | A | 1.1430 | |
| 605 | F | A | 0.0000 | |
| 606 | G | A | -1.2097 | |
| 607 | N | A | -1.0918 | |
| 608 | N | A | -0.9405 | |
| 609 | S | A | 0.0000 | |
| 610 | K | A | 0.0000 | |
| 611 | A | A | 0.2872 | |
| 612 | V | A | 1.1519 | |
| 613 | T | A | -0.1812 | |
| 614 | E | A | -1.7467 | |
| 615 | A | A | 0.0000 | |
| 616 | A | A | 0.0000 | |
| 617 | A | A | -1.3673 | |
| 618 | K | A | -1.2787 | |
| 619 | G | A | -0.7816 | |
| 620 | V | A | 0.0709 | |
| 621 | F | A | 0.4007 | |
| 622 | S | A | -1.1538 | |
| 623 | T | A | -1.6424 | |
| 624 | E | A | -2.7935 | |
| 625 | D | A | -2.8065 | |
| 626 | G | A | 0.0000 | |
| 627 | F | A | 0.0000 | |
| 628 | K | A | -0.7372 | |
| 629 | Y | A | 0.0621 | |
| 630 | F | A | -0.3386 | |
| 631 | A | A | 0.0000 | |
| 632 | P | A | -1.0388 | |
| 633 | A | A | -1.1523 | |
| 634 | N | A | -1.9379 | |
| 635 | T | A | -0.7540 | |
| 636 | L | A | -0.2418 | |
| 637 | D | A | -2.3309 | |
| 638 | E | A | -2.6559 | |
| 639 | N | A | 0.0000 | |
| 640 | L | A | -0.0968 | |
| 641 | E | A | -1.0658 | |
| 642 | G | A | -1.0228 | |
| 643 | E | A | -1.2517 | |
| 644 | A | A | -0.8225 | |
| 645 | I | A | 0.0000 | |
| 646 | D | A | -1.7097 | |
| 647 | F | A | -0.8767 | |
| 648 | T | A | -0.6924 | |
| 649 | G | A | -0.5047 | |
| 650 | K | A | -0.5148 | |
| 651 | L | A | -0.1484 | |
| 652 | I | A | -0.3907 | |
| 653 | I | A | -0.8326 | |
| 654 | D | A | -2.0519 | |
| 655 | E | A | -2.6079 | |
| 656 | N | A | -1.6989 | |
| 657 | I | A | 0.0000 | |
| 658 | Y | A | 0.0000 | |
| 659 | Y | A | -0.0028 | |
| 660 | F | A | 0.0000 | |
| 661 | D | A | -1.2179 | |
| 662 | D | A | -2.2549 | |
| 663 | N | A | -2.1170 | |
| 664 | Y | A | -1.0696 | |
| 665 | R | A | -1.3632 | |
| 666 | G | A | 0.0000 | |
| 667 | A | A | 0.0000 | |
| 668 | V | A | -0.4818 | |
| 669 | G | A | -0.1261 | |
| 670 | V | A | 0.3582 | |
| 671 | F | A | 0.2175 | |
| 672 | N | A | -1.6365 | |
| 673 | T | A | 0.0000 | |
| 674 | E | A | -2.9367 | |
| 675 | D | A | -2.9124 | |
| 676 | G | A | -1.7913 | |
| 677 | F | A | -0.1884 | |
| 678 | K | A | 0.0140 | |
| 679 | Y | A | 1.4307 | |
| 680 | F | A | 1.4593 | |
| 681 | A | A | -0.2620 | |
| 682 | H | A | -0.8079 | |
| 683 | H | A | -0.8347 | |
| 684 | N | A | 0.0000 | |
| 685 | E | A | -1.5065 | |
| 686 | D | A | 0.0000 | |
| 687 | L | A | -0.0549 | |
| 688 | G | A | 0.0000 | |
| 689 | N | A | 0.0000 | |
| 690 | E | A | -2.4036 | |
| 691 | E | A | -2.9156 | |
| 692 | G | A | -2.5635 | |
| 693 | E | A | -2.4125 | |
| 694 | E | A | 0.0000 | |
| 695 | I | A | -1.1087 | |
| 696 | S | A | 0.0000 | |
| 697 | Y | A | 0.0000 | |
| 698 | S | A | -1.0140 | |
| 699 | G | A | -0.6210 | |
| 700 | I | A | 0.2225 | |
| 701 | L | A | -0.1363 | |
| 702 | N | A | -1.5454 | |
| 703 | F | A | -1.1996 | |
| 704 | N | A | -2.0686 | |
| 705 | N | A | -2.2027 | |
| 706 | K | A | -1.5452 | |
| 707 | I | A | 0.0000 | |
| 708 | Y | A | 0.0000 | |
| 709 | Y | A | -0.0238 | |
| 710 | F | A | 0.0000 | |
| 711 | D | A | -1.2627 | |
| 712 | D | A | -2.1753 | |
| 713 | S | A | 0.0000 | |
| 714 | F | A | 0.0000 | |
| 715 | T | A | 0.0000 | |
| 716 | A | A | 0.0000 | |
| 717 | V | A | 0.0000 | |
| 718 | V | A | 0.5998 | |
| 719 | G | A | 1.0281 | |
| 720 | V | A | 1.8541 | |
| 721 | F | A | 0.0000 | |
| 722 | D | A | -0.7819 | |
| 723 | T | A | -0.4887 | |
| 724 | S | A | -1.2403 | |
| 725 | D | A | -2.0667 | |
| 726 | G | A | -1.0087 | |
| 727 | Y | A | 0.6213 | |
| 728 | K | A | 0.7812 | |
| 729 | Y | A | 1.1502 | |
| 730 | F | A | 1.0444 | |
| 731 | A | A | 0.0000 | |
| 732 | P | A | 0.0000 | |
| 733 | A | A | -0.5527 | |
| 734 | N | A | -1.3418 | |
| 735 | T | A | -0.7051 | |
| 736 | V | A | 0.4617 | |
| 737 | N | A | -0.9149 | |
| 738 | D | A | -1.9157 | |
| 739 | N | A | -1.6094 | |
| 740 | I | A | 0.2454 | |
| 741 | Y | A | 0.8612 | |
| 742 | G | A | -0.2356 | |
| 743 | Q | A | -1.0974 | |
| 744 | A | A | 0.0000 | |
| 745 | V | A | 0.0000 | |
| 746 | E | A | -0.9120 | |
| 747 | Y | A | 0.0000 | |
| 748 | S | A | -0.9583 | |
| 749 | G | A | -0.3624 | |
| 750 | L | A | -0.0367 | |
| 751 | V | A | 0.0000 | |
| 752 | R | A | -2.2745 | |
| 753 | V | A | -1.3454 | |
| 754 | G | A | -1.8917 | |
| 755 | E | A | -2.8351 | |
| 756 | D | A | -2.0428 | |
| 757 | V | A | -0.9808 | |
| 758 | Y | A | 0.0000 | |
| 759 | Y | A | 0.0000 | |
| 760 | F | A | 0.0000 | |
| 761 | G | A | -0.6264 | |
| 762 | E | A | -1.5259 | |
| 763 | T | A | -0.8676 | |
| 764 | Y | A | 0.0000 | |
| 765 | T | A | -0.3885 | |
| 766 | I | A | 0.3915 | |
| 767 | E | A | -0.1484 | |
| 768 | T | A | -0.2218 | |
| 769 | G | A | 0.0000 | |
| 770 | W | A | -0.1968 | |
| 771 | I | A | 0.0000 | |
| 772 | G | A | 0.6855 | |
| 773 | V | A | 1.3255 | |
| 774 | F | A | 1.6828 | |
| 775 | N | A | 0.2247 | |
| 776 | T | A | 0.0000 | |
| 777 | P | A | -0.5288 | |
| 778 | D | A | -1.4754 | |
| 779 | G | A | -0.3889 | |
| 780 | F | A | 0.4166 | |
| 781 | K | A | -0.1852 | |
| 782 | Y | A | 0.0000 | |
| 783 | F | A | 0.0000 | |
| 784 | A | A | 0.0000 | |
| 785 | H | A | -1.5688 | |
| 786 | Q | A | -2.5706 | |
| 787 | N | A | -2.2168 | |
| 788 | T | A | -0.9711 | |
| 789 | L | A | -0.3752 | |
| 790 | D | A | -2.3427 | |
| 791 | E | A | -2.6376 | |
| 792 | N | A | -1.7756 | |
| 793 | F | A | -0.8512 | |
| 794 | E | A | -1.8293 | |
| 795 | G | A | 0.0000 | |
| 796 | E | A | -1.2157 | |
| 797 | S | A | -0.4455 | |
| 798 | I | A | 0.1190 | |
| 799 | N | A | -1.0832 | |
| 800 | Y | A | -0.1360 | |
| 801 | T | A | -0.2576 | |
| 802 | G | A | 0.4557 | |
| 803 | W | A | 0.6810 | |
| 804 | L | A | 0.0000 | |
| 805 | D | A | -3.0840 | |
| 806 | L | A | -2.7679 | |
| 807 | D | A | -3.6939 | |
| 808 | E | A | -4.2546 | |
| 809 | K | A | -4.2819 | |
| 810 | R | A | -3.3336 | |
| 811 | Y | A | -0.6412 | |
| 812 | Y | A | 0.6664 | |
| 813 | F | A | 0.0000 | |
| 814 | T | A | -0.8316 | |
| 815 | D | A | -2.4565 | |
| 816 | E | A | -2.4168 | |
| 817 | Y | A | -0.9626 | |
| 818 | I | A | -0.6028 | |
| 819 | A | A | 0.0000 | |
| 820 | A | A | -0.2759 | |
| 821 | T | A | -0.5904 | |
| 822 | H | A | -1.8555 | |
| 823 | H | A | -2.2917 | |
| 824 | H | A | -2.5838 | |
| 825 | H | A | -2.5228 | |
| 826 | H | A | -2.9600 | |
| 827 | H | A | -2.2304 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine