Project name: 5T73

Chain sequence(s)	A: AVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.1994
• Maximal score value: 1.4233
• Average score: -0.9497
• Total score value: -317.1901

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	A	A	-0.5290
3	V	A	-0.8922
4	K	A	-1.1410
5	V	A	0.0000
6	A	A	0.0000
7	I	A	0.0000
8	N	A	0.0000
9	G	A	0.0000
10	F	A	0.0000
11	G	A	-0.4262
12	R	A	-0.6442
13	I	A	-0.0444
14	G	A	0.0000
15	R	A	-0.4385
16	L	A	0.0000
17	A	A	0.0000
18	F	A	0.0000
19	R	A	-0.9365
20	R	A	-1.1018
21	I	A	0.0000
22	Q	A	-2.1462
23	E	A	-2.4917
24	V	A	-1.7928
25	E	A	-2.3325
26	G	A	-1.3652
27	L	A	0.0000
28	E	A	-1.3494
29	V	A	0.0000
30	V	A	-0.9782
31	A	A	0.0000
32	V	A	0.0000
33	N	A	0.0000
34	D	A	-0.0779
35	L	A	0.6780
36	T	A	-0.5452
37	D	A	-2.0356
38	D	A	-2.1279
39	D	A	-2.4769
40	M	A	-1.1624
41	L	A	0.0000
42	A	A	0.0000
43	H	A	-1.0847
44	L	A	-0.4324
45	L	A	0.0000
46	K	A	-1.6294
47	Y	A	-0.5119
48	D	A	-0.6869
49	T	A	-0.1853
50	M	A	-0.0245
51	Q	A	-0.4884
52	G	A	-1.1351
53	R	A	-2.1715
54	F	A	0.0000
55	T	A	-1.4965
56	G	A	-2.1204
57	E	A	-3.4012
58	V	A	0.0000
59	E	A	-3.2179
60	V	A	-1.5802
61	V	A	-1.9147
62	D	A	-2.2766
63	G	A	-1.8722
64	G	A	0.0000
65	F	A	0.0000
66	R	A	-4.0310
67	V	A	0.0000
68	N	A	-2.9006
69	G	A	-2.5090
70	K	A	-2.5343
71	E	A	-3.2287
72	V	A	0.0000
73	K	A	-1.8592
74	S	A	-1.0116
75	F	A	-0.3421
76	S	A	-0.3289
77	E	A	-0.9551
78	P	A	-0.6863
79	D	A	-1.6386
80	A	A	0.0000
81	S	A	-1.9182
82	K	A	-2.4079
83	L	A	0.0000
84	P	A	-1.7730
85	W	A	0.0000
86	K	A	-3.4313
87	D	A	-2.9340
88	L	A	-2.1109
89	N	A	-2.6764
90	I	A	0.0000
91	D	A	-1.5996
92	V	A	0.0000
93	V	A	0.0000
94	L	A	0.0000
95	E	A	0.0000
96	C	A	0.2158
97	T	A	0.4008
98	G	A	0.4750
99	F	A	1.4233
100	Y	A	-0.1274
101	T	A	-0.5413
102	D	A	-1.9563
103	K	A	-2.7511
104	D	A	-3.3659
105	K	A	-2.6201
106	A	A	0.0000
107	Q	A	-1.8826
108	A	A	-1.8272
109	H	A	0.0000
110	I	A	-1.1305
111	E	A	-2.3459
112	A	A	-2.2478
113	G	A	-2.5278
114	A	A	0.0000
115	K	A	-1.9042
116	K	A	0.0000
117	V	A	0.0000
118	L	A	0.0000
119	I	A	0.0000
120	S	A	0.0000
121	A	A	-0.1934
122	P	A	-0.6072
123	A	A	-1.1940
124	T	A	-1.4833
125	G	A	-2.3512
126	D	A	-2.5662
127	L	A	0.0000
128	K	A	-1.4305
129	T	A	0.0000
130	I	A	0.0000
131	V	A	0.0000
132	F	A	-0.4148
133	N	A	-0.9536
134	T	A	0.0000
135	N	A	0.0000
136	H	A	-1.4411
137	Q	A	-2.2036
138	E	A	-2.4343
139	L	A	0.0000
140	D	A	-2.4691
141	G	A	-1.7125
142	S	A	-0.8239
143	E	A	0.0000
144	T	A	-0.3641
145	V	A	0.0000
146	V	A	0.0000
147	S	A	0.0000
148	G	A	0.0000
149	A	A	0.0000
150	S	A	-0.2242
152	T	A	-0.1279
153	T	A	0.0000
154	N	A	0.0000
155	S	A	0.0000
156	L	A	0.0000
157	A	A	0.0000
158	P	A	-0.2306
159	V	A	0.0000
160	A	A	0.0000
161	K	A	-1.5270
162	V	A	-1.6063
163	L	A	0.0000
164	N	A	-2.3270
165	D	A	-2.7683
166	D	A	-2.7800
167	F	A	0.0000
168	G	A	-2.3370
169	L	A	0.0000
170	V	A	-1.0280
171	E	A	-1.9312
172	G	A	-0.3911
173	L	A	0.3626
174	M	A	0.0000
175	T	A	-0.0895
176	T	A	0.0000
177	I	A	0.6151
178	H	A	0.3723
179	A	A	0.0000
180	Y	A	0.0813
181	T	A	-0.4975
182	G	A	-0.9617
183	D	A	-1.5641
184	Q	A	0.0000
185	N	A	-2.1405
186	T	A	-1.8467
187	Q	A	-2.7713
188	D	A	-3.3480
189	A	A	-2.1653
190	P	A	-2.1841
191	H	A	-3.0681
192	R	A	-3.1681
193	K	A	-3.3551
194	G	A	-2.7370
195	D	A	-2.7921
196	K	A	-3.1386
197	R	A	-2.2922
198	R	A	-2.7408
199	A	A	-3.3038
200	R	A	-3.2661
201	A	A	0.0000
202	A	A	0.0000
203	A	A	-0.8800
204	E	A	-1.7813
205	N	A	-0.4144
206	I	A	1.3048
207	I	A	0.0000
208	P	A	-0.0633
209	N	A	0.0000
210	S	A	-0.4778
211	T	A	-0.9011
212	G	A	-1.2236
213	A	A	0.0000
214	A	A	0.0000
215	K	A	-2.6714
216	A	A	-1.9083
217	I	A	0.0000
218	G	A	-2.3802
219	K	A	-2.0078
220	V	A	0.0000
221	I	A	0.0000
222	P	A	-2.1441
223	E	A	-2.8678
224	I	A	0.0000
225	D	A	-3.5131
226	G	A	-2.7817
227	K	A	-2.4060
228	L	A	0.0000
229	D	A	-1.6567
230	G	A	-0.6731
231	G	A	-0.5767
232	A	A	0.0000
233	Q	A	0.1612
234	R	A	0.3331
235	V	A	0.5934
236	P	A	0.0241
237	V	A	0.2493
238	A	A	0.2324
239	T	A	0.0000
240	G	A	0.0000
241	S	A	0.0000
242	L	A	0.3640
243	T	A	0.0000
244	E	A	-0.4798
245	L	A	0.0000
246	T	A	-0.0892
247	V	A	0.0000
248	V	A	-0.8920
249	L	A	-2.1521
250	E	A	-3.4298
251	K	A	-3.9597
252	Q	A	-4.1994
253	D	A	-3.7485
254	V	A	0.0000
255	T	A	-1.5410
256	V	A	-1.3200
257	E	A	-2.6456
258	Q	A	-2.5594
259	V	A	0.0000
260	N	A	-2.7533
261	E	A	-3.5126
262	A	A	-2.8182
263	M	A	0.0000
264	K	A	-2.9650
265	N	A	-2.6445
266	A	A	-1.6243
267	S	A	-1.8720
268	N	A	-1.8774
269	E	A	-1.9829
270	S	A	0.0000
271	F	A	0.0000
272	G	A	0.0000
273	Y	A	-1.3831
274	T	A	-1.8249
275	E	A	-3.1620
276	D	A	-3.2314
277	E	A	-2.6830
278	I	A	-0.9671
279	V	A	0.8085
280	S	A	0.4506
281	S	A	-0.3509
282	D	A	-1.1652
283	V	A	0.0000
284	V	A	-0.1367
285	G	A	-0.2512
286	M	A	0.0394
287	T	A	-0.0026
288	Y	A	0.0866
289	G	A	0.0000
290	S	A	0.0000
291	L	A	0.0000
292	F	A	0.0000
293	D	A	0.0000
294	A	A	0.0000
295	T	A	-1.6977
296	Q	A	-1.4901
297	T	A	0.0000
298	R	A	-1.3270
299	V	A	-0.3989
300	M	A	0.1465
301	S	A	-0.5979
302	V	A	0.5022
303	G	A	-1.0604
304	D	A	-3.0537
305	R	A	-3.1220
306	Q	A	-1.6894
307	L	A	0.2000
308	V	A	0.0000
309	K	A	-0.7176
310	V	A	0.0000
311	A	A	0.0000
312	A	A	0.0000
313	W	A	0.3642
314	Y	A	0.0000
315	D	A	0.0000
316	N	A	-0.1145
317	E	A	-0.2072
318	M	A	-0.0121
319	S	A	0.0000
320	Y	A	0.0000
321	T	A	0.0000
322	A	A	0.0000
323	Q	A	0.0000
324	L	A	0.0000
325	V	A	0.0000
326	R	A	-0.1327
327	T	A	0.0000
328	L	A	0.0000
329	A	A	-0.3740
330	Y	A	-0.6246
331	L	A	0.0000
332	A	A	-1.2788
333	E	A	-2.0729
334	L	A	-1.6281
335	S	A	-1.6474
336	K	A	-2.1521